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My trajectory after a "vacation" and a new metastasis
My backgound briefly (full details in Profile): aggressive form, BRCA2 mutation, RP in 2017, then 39 sessions of radiation, and 3 yrs of Lupron. All at Smilow Cancer Hospital. As a result, my PSA was undetectable for 2.5 years, and in 9/21 I was put on a "vacation" from treatment. Then PSA started
My backgound briefly (full details in Profile): aggressive form, BRCA2 mutation, RP in 2017, then 39 sessions of radiation, and 3 yrs of Lupron. All at Smilow Cancer Hospital. As a result, my PSA was undetectable for 2.5 years, and in 9/21 I was put on a "vacation" from treatment. Then PSA started
Istomin
in
Advanced Prostate Cancer
8 months ago
Stage 4 OC with liver metastasis
Any guidance or anyone with Cancer metastasis to Liver? My mother has stage 4 Ovarian Cancer which even after chemo has spread to Liver. Her bilrubin levels are not coming under control infact are increasing and situation is not improving. She’s extremely weak and low on energy. Doctors saying nothing
Any guidance or anyone with Cancer metastasis to Liver? My mother has stage 4 Ovarian Cancer which even after chemo has spread to Liver. Her bilrubin levels are not coming under control infact are increasing and situation is not improving. She’s extremely weak and low on energy. Doctors saying nothing
akhilsalwan
in
SHARE Ovarian Cancer Support
4 months ago
Stage 4 OC with Liver Metastasis
Any guidance or anyone with Cancer metastasis to Liver? My mother has stage 4 Ovarian Cancer which even after chemo has spread to Liver. Her bilrubin levels are not coming under control infact are increasing and situation is not improving. She’s extremely weak and low on energy. Doctors saying nothing
Any guidance or anyone with Cancer metastasis to Liver? My mother has stage 4 Ovarian Cancer which even after chemo has spread to Liver. Her bilrubin levels are not coming under control infact are increasing and situation is not improving. She’s extremely weak and low on energy. Doctors saying nothing
akhilsalwan
in
My Ovacome
4 months ago
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Stage 4 OC with Liver Metastasis
Any guidance or anyone with Cancer metastasis to Liver? My mother has stage 4 Ovarian Cancer which even after chemo has spread to Liver. Her bilrubin levels are not coming under control infact are increasing and situation is not improving. She’s extremely weak and low on energy. Doctors saying nothing
Any guidance or anyone with Cancer metastasis to Liver? My mother has stage 4 Ovarian Cancer which even after chemo has spread to Liver. Her bilrubin levels are not coming under control infact are increasing and situation is not improving. She’s extremely weak and low on energy. Doctors saying nothing
akhilsalwan
in
OvaCare
4 months ago
T4 and integrin receptors
I've come across integrin receptors mentioned in a few papers recently where t4 seems to have some activity (generally its assumed t4 is not an active hormone), so was interested to read the following paper. This is yet another good reason for t3/t4 combination treatment. "Preliminary clinical evidence
I've come across integrin receptors mentioned in a few papers recently where t4 seems to have some activity (generally its assumed t4 is not an active hormone), so was interested to read the following paper. This is yet another good reason for t3/t4 combination treatment. "Preliminary clinical evidence
Forestgarden
in
Thyroid UK
6 months ago
Wondering if I should get a Partial Thyroidectomy?
I have a nodule on the left side of my thyroid which grew from 11 x 5 x 7 mm to 14 x 9 x 7 mm over the last 6 months. My endocrinologist and ENT believe it’s cancer. No impact on my lymph nodes. My surgery is in a few days and I’m just nervous I’m removing a part of my body that could be fine. Any
I have a nodule on the left side of my thyroid which grew from 11 x 5 x 7 mm to 14 x 9 x 7 mm over the last 6 months. My endocrinologist and ENT believe it’s cancer. No impact on my lymph nodes. My surgery is in a few days and I’m just nervous I’m removing a part of my body that could be fine. Any
happycamper143
in
Thyroid Cancer Support
6 months ago
More Evidence Linking ADT for PCa to Adverse Neurocognitive Effects -Meta-analysis shows increased risk of dementia, Parkinson's, depression
[i]As if we needed more reasons to dislike or avoid ADT, here is additional evidence of negative neurocognitive effects. This MedPage Today article will expecially be of special interest to those of us well into our "Golden Years" and on or considering ADT. [/i]
More Evidence Linking ADT for Prostate
[i]As if we needed more reasons to dislike or avoid ADT, here is additional evidence of negative neurocognitive effects. This MedPage Today article will expecially be of special interest to those of us well into our "Golden Years" and on or considering ADT. [/i]
More Evidence Linking ADT for Prostate
cujoe
in
Fight Prostate Cancer
6 months ago
Steroids and Radium 223
Hi Hopefully my husband will start Radium 223 in 4-6 weeks. He recently stopped abiraterone after 5 months as his PSA was doubling every month. While he was on abiraterone he was taking 2mgs of dexamethasone, although 1mg for the last month. He’s currently taking 6mgs of prednisilone but our question
Hi Hopefully my husband will start Radium 223 in 4-6 weeks. He recently stopped abiraterone after 5 months as his PSA was doubling every month. While he was on abiraterone he was taking 2mgs of dexamethasone, although 1mg for the last month. He’s currently taking 6mgs of prednisilone but our question
NLondon43
in
Advanced Prostate Cancer
8 months ago
Signatera tumor dna test
Has anyone heard of using the Signatera test from Natera to detect the presence of prostate cancer recurrence when PSA is rising but the PSMA PET scan is negative?
Has anyone heard of using the Signatera test from Natera to detect the presence of prostate cancer recurrence when PSA is rising but the PSMA PET scan is negative?
shihtzu124
in
Advanced Prostate Cancer
8 months ago
PSA Dropped after 22 days of Zytiga
On Nov 1, my cancer was diagnosed as castrate resistant. Abiraterone and Prednisone was added to Lupron. On November 3 I had a Lupron shot and started Abiraterone and Prednisone on November 10. Today I had a PSA test. My PSA dropped from 0.8 on November 1 to 0.44 today. I was not expecting such dramatic
On Nov 1, my cancer was diagnosed as castrate resistant. Abiraterone and Prednisone was added to Lupron. On November 3 I had a Lupron shot and started Abiraterone and Prednisone on November 10. Today I had a PSA test. My PSA dropped from 0.8 on November 1 to 0.44 today. I was not expecting such dramatic
dac500
in
Advanced Prostate Cancer
8 months ago
Here we go again
I was doing better, now the stomach pain is back worse than before. I guess its my own fault for eating McDonald's I was reading that unexplained weight loss could be colon cancer. I'm not sure it is unexplained as I have cut a lot of foods out. Processed foods . I'm just so scared to go to the
I was doing better, now the stomach pain is back worse than before. I guess its my own fault for eating McDonald's I was reading that unexplained weight loss could be colon cancer. I'm not sure it is unexplained as I have cut a lot of foods out. Processed foods . I'm just so scared to go to the
Ceasersalad
in
IBS Network
8 months ago
Lloyd Austin
"Washington CNN Defense Secretary Lloyd Austin is being treated for prostate cancer and suffered complications that led to him being taken to hospital on New Year’s Day where he is still being treated, according to a statement Tuesday from Walter Reed National Military Medical Center. The statement
"Washington CNN Defense Secretary Lloyd Austin is being treated for prostate cancer and suffered complications that led to him being taken to hospital on New Year’s Day where he is still being treated, according to a statement Tuesday from Walter Reed National Military Medical Center. The statement
Justfor_
in
Fight Prostate Cancer
6 months ago
Heterogeneous Metastases?
I was first diagnosed Stage3 in Aug. 2014, ER+PR+Her2-. Found metastases in bones and lymph nodes in Dec. 2023, bioposied one node, same biomarkers. I was put on Tamoxifen which shrank many lesions, except for one. After that, I went through Tamoxifen, Letrozole + Kisqali, Faslodex + Kisqali, have scan
I was first diagnosed Stage3 in Aug. 2014, ER+PR+Her2-. Found metastases in bones and lymph nodes in Dec. 2023, bioposied one node, same biomarkers. I was put on Tamoxifen which shrank many lesions, except for one. After that, I went through Tamoxifen, Letrozole + Kisqali, Faslodex + Kisqali, have scan
Faith999
in
SHARE Metastatic Breast Cancer
5 months ago
Atelectasis?
I have seen several people refer to this here, but didn't know what it was. My PET/CT scan on Friday showed some mildly alarming things -- bone met in spine is shrinking, but a bunch of subcentimeter but metabolically active lymph nodes around the lungs (hila, paratrachea, mediastinal-pleural). Not
I have seen several people refer to this here, but didn't know what it was. My PET/CT scan on Friday showed some mildly alarming things -- bone met in spine is shrinking, but a bunch of subcentimeter but metabolically active lymph nodes around the lungs (hila, paratrachea, mediastinal-pleural). Not
TammyCross
in
SHARE Metastatic Breast Cancer
5 months ago
XTX-301: immunotherapy for cold tumors
It's being developed also for prostate cancer even if the article does not mention it: https://www.globenewswire.com/news-release/2024/01/08/2805332/0/en/Xilio-Therapeutics-Highlights-Recent-Advances-Across-Clinical-Pipeline-and-Encouraging-Preliminary-Phase-1-Safety-Data-for-XTX301-a-Tumor-Activated-IL
It's being developed also for prostate cancer even if the article does not mention it: https://www.globenewswire.com/news-release/2024/01/08/2805332/0/en/Xilio-Therapeutics-Highlights-Recent-Advances-Across-Clinical-Pipeline-and-Encouraging-Preliminary-Phase-1-Safety-Data-for-XTX301-a-Tumor-Activated-IL
Maxone73
in
Advanced Prostate Cancer
6 months ago
Reaction to Taxol (Paclitaxel) and alternatives?
Hi- I was diagnosed with primary peritoneal cancer in Jan 2024. I had my first chemo last week and reacted to the taxol (paclitaxel) so could only receive bev and carboplatin. I will be switched to taxotere for my next treatment. Wondering if anyone else has had a reaction to taxol and then received
Hi- I was diagnosed with primary peritoneal cancer in Jan 2024. I had my first chemo last week and reacted to the taxol (paclitaxel) so could only receive bev and carboplatin. I will be switched to taxotere for my next treatment. Wondering if anyone else has had a reaction to taxol and then received
ajtbq
in
SHARE Ovarian Cancer Support
5 months ago
Ranolazine (used for angina) could potentially be repurposed for PCa. Only mouse studies so far.
“Treatment of cancer patients with lipid metabolic inhibitors like ranolazine could potentially re-activate the immune cells to restore and enhance cellular-mediated antitumor immunity and tumor regression.” Targeting Fat Oxidation in Mouse Prostate Cancer Decreases Tumor Growth and Stimulates Anti-Cancer
“Treatment of cancer patients with lipid metabolic inhibitors like ranolazine could potentially re-activate the immune cells to restore and enhance cellular-mediated antitumor immunity and tumor regression.” Targeting Fat Oxidation in Mouse Prostate Cancer Decreases Tumor Growth and Stimulates Anti-Cancer
Graham49
in
Advanced Prostate Cancer
5 months ago
Result of Liver Biopsy - Any Insights?
This is the result of my liver biposy. Any insights on the comment? ----- CLINICAL HISTORY>>:: Prostate Ca with hepatic mets ?Small cell transformation versus other. FINAL DIAGNOSIS>>:: LIVER NODULE, CORE BIOPSY: - POORLY DIFFERENTIATED PROSTATIC ADENOCARCINOMA WITH SMALL CELL TRANSFORMATION
This is the result of my liver biposy. Any insights on the comment? ----- CLINICAL HISTORY>>:: Prostate Ca with hepatic mets ?Small cell transformation versus other. FINAL DIAGNOSIS>>:: LIVER NODULE, CORE BIOPSY: - POORLY DIFFERENTIATED PROSTATIC ADENOCARCINOMA WITH SMALL CELL TRANSFORMATION
skiingfiend
in
Advanced Prostate Cancer
5 months ago
Combine standard care with alternative care
The University of Maryland reported two cases of terminated PCs by combining standard care treatment with an alternative treatment. By reducing the PSAs to less than 3, the clioquinol + zinc killed more cancer than testosterone could renew, therefore termination. My PSA in three months went from 58
The University of Maryland reported two cases of terminated PCs by combining standard care treatment with an alternative treatment. By reducing the PSAs to less than 3, the clioquinol + zinc killed more cancer than testosterone could renew, therefore termination. My PSA in three months went from 58
agnut
in
Fight Prostate Cancer
8 months ago
brachytherapy
my hubbie has just had brachytherapy for stage 3 prostate and has been in great pain since Thursday. He’s been told it’s normal and to suck it up but he’s not sleeping and is struggling to wee without great pain (tears) . Any advice as to what has worked for you to manage post op brachytherapy please
my hubbie has just had brachytherapy for stage 3 prostate and has been in great pain since Thursday. He’s been told it’s normal and to suck it up but he’s not sleeping and is struggling to wee without great pain (tears) . Any advice as to what has worked for you to manage post op brachytherapy please
bikebabe
in
Prostate Cancer Network
5 months ago
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