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Sinemet
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Parkinson's wife
I have a feeling that the problem with Madopar and
Sinemet
is the decarboxylase inhibitor which blocks vit B6. This vitamin is vital to so may other functions in the body. Anyone else found the same ? Any advice appreciated.
I have a feeling that the problem with Madopar and
Sinemet
is the decarboxylase inhibitor which blocks vit B6. This vitamin is vital to so may other functions in the body. Anyone else found the same ? Any advice appreciated.
veronicacoath
in
Cure Parkinson's
11 months ago
Food and "off" times
I know about keeping proteins away from
sinemet
as they compete for the same receptors in the gut. I can time my dose of
sinemet
(a generic, 25/100, 3 x day) an hour before eating a meal, feeling just fine. Then like clockwork, about a half an hour later my symptoms return.
I know about keeping proteins away from
sinemet
as they compete for the same receptors in the gut. I can time my dose of
sinemet
(a generic, 25/100, 3 x day) an hour before eating a meal, feeling just fine. Then like clockwork, about a half an hour later my symptoms return.
PDFree
in
Cure Parkinson's
11 months ago
Has anybody found a way to reduce dyskinesia without Amantadine?
For many years,
sinemet
worked fine for me, but now I'm one of those people who gets dyskinesia from it. I've tried different combinations of amantadine and GoCovri (extended release). but it doesn't have much effect. So I take as little
Sinemet
as I can get away with. First dose at noon.
For many years,
sinemet
worked fine for me, but now I'm one of those people who gets dyskinesia from it. I've tried different combinations of amantadine and GoCovri (extended release). but it doesn't have much effect. So I take as little
Sinemet
as I can get away with. First dose at noon.
craigwharris
in
Cure Parkinson's
1 year ago
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Levodopa vs Other Parkinson medicines against Fatigue
My questions are: Although
Sinemet
is reduced significantlyand also no more Constant Release tablets in the new neuro's medication list, still the other medicine doses have been made high.
My questions are: Although
Sinemet
is reduced significantlyand also no more Constant Release tablets in the new neuro's medication list, still the other medicine doses have been made high.
gdineshnathan
in
Cure Parkinson's
1 year ago
K0706 Clinical Trial
I'm recently diagnosed and have not started any PD meds, though my neurologist says
Sinemet
would probably help my symptoms. I'm not having terrible or disruptive symptoms, just an annoying leg tremor, fatigue and stiffness. I see a PT and exercise, which really helps with the stiffness.
I'm recently diagnosed and have not started any PD meds, though my neurologist says
Sinemet
would probably help my symptoms. I'm not having terrible or disruptive symptoms, just an annoying leg tremor, fatigue and stiffness. I see a PT and exercise, which really helps with the stiffness.
Salted
in
Cure Parkinson's
11 months ago
IPX203 shows sustained safety, efficacy in RISE-PD extension trial
The aim is to enable the medication to stay at clinically relevant doses in the bloodstream longer, extending motor symptom control relative to standard, immediate-release CD/LD therapies such as
Sinemet
.
The aim is to enable the medication to stay at clinically relevant doses in the bloodstream longer, extending motor symptom control relative to standard, immediate-release CD/LD therapies such as
Sinemet
.
Farooqji
in
Cure Parkinson's
9 months ago
Practical suggestions for PWP.....Hedge against medication scarcity.
At times i have requested an extra dose of for example,
Sinemet
. Such as, I tell the Dr. I need to increase my dose by one. I do this until , at the very least, I have enough extras to titrate off safely.
At times i have requested an extra dose of for example,
Sinemet
. Such as, I tell the Dr. I need to increase my dose by one. I do this until , at the very least, I have enough extras to titrate off safely.
beehive23
in
Cure Parkinson's
11 months ago
Frightening Experience
I had started the day off with a later than usual dose of
Sinemet
(25/250) and had given enough time - about an hour for the most recent dose to kick in. Yet, after reaching home I couldn't get out of the car. I had just totally lost my will power!I was also intensely panicked and scared.
I had started the day off with a later than usual dose of
Sinemet
(25/250) and had given enough time - about an hour for the most recent dose to kick in. Yet, after reaching home I couldn't get out of the car. I had just totally lost my will power!I was also intensely panicked and scared.
pdpatient
in
Cure Parkinson's
9 months ago
Are there common side-effects to Rytary withdrawal?
Before that I had been on
Sinemet
for 4 years. I quit taking Rytary about a month ago. My only side effect seems to be insomnia. Maybe insomnia is the wrong word. Eventually I get tired and can sleep for a few hours. But I doubt it adds up to 8 hours over 24 hours.
Before that I had been on
Sinemet
for 4 years. I quit taking Rytary about a month ago. My only side effect seems to be insomnia. Maybe insomnia is the wrong word. Eventually I get tired and can sleep for a few hours. But I doubt it adds up to 8 hours over 24 hours.
kaypeeoh
in
Cure Parkinson's
1 year ago
Neurologist recommendation
Hello My husband has recently been diagnosed and has started on
Sinemet
but it is not helping his terrible leg spasms.
Hello My husband has recently been diagnosed and has started on
Sinemet
but it is not helping his terrible leg spasms.
markland
in
Cure Parkinson's
1 year ago
PD with Peripheral neuropathy ? (not diabetic) Taking Sinemet with Gabapentin...
These 2 drugs make me dizzy and spacy I can barely function as day goes on.Anyone out there have some advice? I'm at my wits end!!
These 2 drugs make me dizzy and spacy I can barely function as day goes on.Anyone out there have some advice? I'm at my wits end!!
Lyrics19
in
Cure Parkinson's
10 months ago
madopar vs sinemet
I’m planning to switch from
sinemet
125 mg (levodopa carbidopa combination) immediate release to madopar Controlled release 125 mg (levodopa benserazide). Based on your experience, do you think it’s safe n is a good idea?
I’m planning to switch from
sinemet
125 mg (levodopa carbidopa combination) immediate release to madopar Controlled release 125 mg (levodopa benserazide). Based on your experience, do you think it’s safe n is a good idea?
Divii
in
Cure Parkinson's
1 year ago
99% Mucuna worsening Tremor
Except for a brief honeymoon period shortly after dx,
Sinemet
also didn't help but after waiting 9 months I'm finally slated for an Ldopa challenge in a couple of weeks. Thoughts, experience, insight? Thanks and best to all.
Except for a brief honeymoon period shortly after dx,
Sinemet
also didn't help but after waiting 9 months I'm finally slated for an Ldopa challenge in a couple of weeks. Thoughts, experience, insight? Thanks and best to all.
Dabaa
in
Cure Parkinson's
2 months ago
Emotional toll
I only recently started taking
sinemet
(I was trying to go about this without medication and use only supplements and regular exercise). The
sinemet
has helped with my overall energy, bradykinesia, stiffness among other symptoms.
I only recently started taking
sinemet
(I was trying to go about this without medication and use only supplements and regular exercise). The
sinemet
has helped with my overall energy, bradykinesia, stiffness among other symptoms.
Fatherof5
in
Cure Parkinson's
1 year ago
Sinemet not working.
I was diagnosed in 2021 and have been taking this and doing well. I'm up to 1 1/2 tabs(25-100) 5 x a day. In the last few weeks, I get b anxious, lightheaded and weak about 15 minutes after taking my meds. It completely shuts me down . I'm waiting on my neurologist for directions. One was to switch
I was diagnosed in 2021 and have been taking this and doing well. I'm up to 1 1/2 tabs(25-100) 5 x a day. In the last few weeks, I get b anxious, lightheaded and weak about 15 minutes after taking my meds. It completely shuts me down . I'm waiting on my neurologist for directions. One was to switch
Gigi_12
in
Cure Parkinson's
1 year ago
When does Opicapone work?
I started 2 nights ago at 11pm after 400 mg di
Sinemet
during the day, but it is like to eat a candy: nothing happens 🫥
I started 2 nights ago at 11pm after 400 mg di
Sinemet
during the day, but it is like to eat a candy: nothing happens 🫥
michelagvolpe
in
Cure Parkinson's
1 year ago
Auditory hallucinations
She is also taking
Sinemet
25/100mg every 4 hours, with the controlled release version taken before bed. We will discuss the above with her neurologist at her next appointment, but in the meantime any ideas that may help her to cope will be most appreciated. Thank you
She is also taking
Sinemet
25/100mg every 4 hours, with the controlled release version taken before bed. We will discuss the above with her neurologist at her next appointment, but in the meantime any ideas that may help her to cope will be most appreciated. Thank you
NJCOL
in
Cure Parkinson's
1 year ago
any CARNIVORE DIETers out there?
I even forgot to take my afternoon dose of
Sinemet
until an hour after I usually take it and completely forgot to take my evening dose, because there were no symptoms when they usually remind me to take it, Still a little bradykinesia at this point. No brain fog.
I even forgot to take my afternoon dose of
Sinemet
until an hour after I usually take it and completely forgot to take my evening dose, because there were no symptoms when they usually remind me to take it, Still a little bradykinesia at this point. No brain fog.
bassofspades
in
Cure Parkinson's
10 months ago
UPDATE: Dad's Surgery on Broken Ankle Bone and Resulting PSYCHOSIS. QUESTION: How do you deal with Episodes of Hallucinations & Delusions?
We are monitoring closely his dosing of BOTH
SINEMET
& ZANDOPA, and have found a better strategy so far for keeping BOTH PHYSICAL MOTOR SYMPTOMS & MENTAL SYMPTOMS as good as possible without making one too much worse.
We are monitoring closely his dosing of BOTH
SINEMET
& ZANDOPA, and have found a better strategy so far for keeping BOTH PHYSICAL MOTOR SYMPTOMS & MENTAL SYMPTOMS as good as possible without making one too much worse.
rsacdoolittle
in
Cure Parkinson's
1 year ago
Does anyone else have a weird version of sciatica/neuropathy?
Somewhat alleviated by CL (
sinemet
) but only for about an hour. It feels like nerves in feet legs hip and shoulder are literally writhing and [u]vibrating[/u]. Hubby can actually see them moving under skin. There’s pain but not terrible. More like itching and nasty tickles.
Somewhat alleviated by CL (
sinemet
) but only for about an hour. It feels like nerves in feet legs hip and shoulder are literally writhing and [u]vibrating[/u]. Hubby can actually see them moving under skin. There’s pain but not terrible. More like itching and nasty tickles.
Gallowglass
in
Cure Parkinson's
4 months ago
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