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deciding whether to do pluvicto with hemoglobin around 8
Metastatic prostate cancer to multiple lymph nodes, lungs, bone Mets to spine, ribs, pelvis, femur. PSA 22. Gleason 9. ADT for 7 years, failed zytiga after being on it for 3 years, failed 3 rounds of doxetaxol this past fall. Radiation treatments to pelvis in 2021 and spine, hip in 2023. Had BRCA mutations
Metastatic prostate cancer to multiple lymph nodes, lungs, bone Mets to spine, ribs, pelvis, femur. PSA 22. Gleason 9. ADT for 7 years, failed zytiga after being on it for 3 years, failed 3 rounds of doxetaxol this past fall. Radiation treatments to pelvis in 2021 and spine, hip in 2023. Had BRCA mutations
LJGD
in
Advanced Prostate Cancer
5 months ago
Low-T is associated with worse Prostate Cancer Specific Mortality probability after 6 months of ADT: Part III
Here are comparisons of the
Prostate Cancer Specific Mortality (PCSM) probability (%
) for two different testosterone levels (
Low-T and Normal-T
) and four different
Times After PSA Failure
from the Kaplan-Meier plot previously posted. (Atkins 2018). The median testosterone for
Here are comparisons of the
Prostate Cancer Specific Mortality (PCSM) probability (%
) for two different testosterone levels (
Low-T and Normal-T
) and four different
Times After PSA Failure
from the Kaplan-Meier plot previously posted. (Atkins 2018). The median testosterone for
janebob99
in
Prostate Cancer Network
5 months ago
Low-T is associated with worse Prostate Cancer Specific Mortality probability after 6 months of ADT: Part II
Here are comparisons of the Prostate Cancer Specific Mortality (PCSM) probability (%) for two different testosterone levels (Low-T and Normal-T)and three different Times After PSA Failure from Atkins (2018). he median testosterone for the Low-T group is T = 162 ng/dL [120-236], and I assumed an average
Here are comparisons of the Prostate Cancer Specific Mortality (PCSM) probability (%) for two different testosterone levels (Low-T and Normal-T)and three different Times After PSA Failure from Atkins (2018). he median testosterone for the Low-T group is T = 162 ng/dL [120-236], and I assumed an average
janebob99
in
Prostate Cancer Network
5 months ago
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bilateral oophorectomy at 34
Hi all, I am looking to hear from real people (you folks on this forum) about your experiences for a bilateral oophorectomy. I have been suffering with debilitating endometriosis symptoms for more than a decade and on Monday March 4th I saw a consultant about my treatment steps. She was the surgeon
Hi all, I am looking to hear from real people (you folks on this forum) about your experiences for a bilateral oophorectomy. I have been suffering with debilitating endometriosis symptoms for more than a decade and on Monday March 4th I saw a consultant about my treatment steps. She was the surgeon
HomebodyFig
in
Endometriosis UK
5 months ago
Treatment Resistant Depressant
I have had depression since my 20’s and likely in teens. I’m now 56 and my meds are no longer working like they once did. I’m going to be meeting with a clinic about other options ie: ECT etc. I’m very scared and anxious as this feels next level to me in my illness. Have you tried ECT and/or Esketamine
I have had depression since my 20’s and likely in teens. I’m now 56 and my meds are no longer working like they once did. I’m going to be meeting with a clinic about other options ie: ECT etc. I’m very scared and anxious as this feels next level to me in my illness. Have you tried ECT and/or Esketamine
Doubledog
in
Anxiety and Depression Support
7 months ago
Fears confirmed
I posted previously on this long and tortuous journey to ( almost) a diagnosis. Almost because my concierge PCP gave me a heads up on the biopsy report which hasn’t been posted on my digital chart and I haven’t yet heard from my Urologist/ Onocologist. It’s been 4 mos since my annual checkup said my
I posted previously on this long and tortuous journey to ( almost) a diagnosis. Almost because my concierge PCP gave me a heads up on the biopsy report which hasn’t been posted on my digital chart and I haven’t yet heard from my Urologist/ Onocologist. It’s been 4 mos since my annual checkup said my
Willie51
in
Prostate Cancer And Gay Men
5 months ago
Medicare Part D decision
So, I'm going on Medicare in April. I've enrolled in the Blue Cross Plan G Supplement plan and am now trying to decide which Part D plan to get for meds. At the moment my main concern is what it's going to cost for my new Abiraterone prescription. It looks like BCBS is going to be too expensive. Their
So, I'm going on Medicare in April. I've enrolled in the Blue Cross Plan G Supplement plan and am now trying to decide which Part D plan to get for meds. At the moment my main concern is what it's going to cost for my new Abiraterone prescription. It looks like BCBS is going to be too expensive. Their
fireandice123
in
Advanced Prostate Cancer
5 months ago
Relugolix/Orgovyx or Enzalutamide/Xtandi?
Good morning, all. I have updated my profile with my husband's history. But, long story short, he has been on ADT vacation for 13 months following succesful treatment of metastatic disease with Triplet Therapy (six rounds of Docetaxel, Lupron, and first Abieraterone plus Prednisone and then he switched
Good morning, all. I have updated my profile with my husband's history. But, long story short, he has been on ADT vacation for 13 months following succesful treatment of metastatic disease with Triplet Therapy (six rounds of Docetaxel, Lupron, and first Abieraterone plus Prednisone and then he switched
FaithOverFear104
in
Advanced Prostate Cancer
5 months ago
Magnesium, zinc and calcium
Nearly a year after ADT and all clear with testosterone recovering well. Been advised by a fellow runner to try a supplement of magnesium, zinc and calcium. The Onco has no objections. Are there reasons no too? Thank you.
Nearly a year after ADT and all clear with testosterone recovering well. Been advised by a fellow runner to try a supplement of magnesium, zinc and calcium. The Onco has no objections. Are there reasons no too? Thank you.
Runner1957
in
Prostate Cancer Network
5 months ago
New Member
HI everyone. I have another scan next month, and I am not looking forward to what it will say. I found out in 2018 I have osteopenia. My doctor believes I am in stage 2/3 now. I fell 2 years ago on the ground next to my car. I rebroke my foot in the same spot as 4 years earlier from a head on collision
HI everyone. I have another scan next month, and I am not looking forward to what it will say. I found out in 2018 I have osteopenia. My doctor believes I am in stage 2/3 now. I fell 2 years ago on the ground next to my car. I rebroke my foot in the same spot as 4 years earlier from a head on collision
numbercruncherak
in
PMRGCAuk
11 months ago
Testosterone volatility
My testosterone was measured @ 490 in 2014 when I was DX with PCa Gleason 6, it was measured again in 2016 at 463. It was not measured again until after I started on ADT and it has been >7 ever since. Is there a way for me to extrapolate what it would have been in 2021 when I was DX with Gleason
My testosterone was measured @ 490 in 2014 when I was DX with PCa Gleason 6, it was measured again in 2016 at 463. It was not measured again until after I started on ADT and it has been >7 ever since. Is there a way for me to extrapolate what it would have been in 2021 when I was DX with Gleason
Scout4answers
in
Prostate Cancer Network
5 months ago
good evening....
I'm trying to stay positive and help everyone come up with ideas for journaling, artwork, ect....I try not to get carried away with my posts.....trying not to be too pushy....will you please let me know if i get too carried away
I'm trying to stay positive and help everyone come up with ideas for journaling, artwork, ect....I try not to get carried away with my posts.....trying not to be too pushy....will you please let me know if i get too carried away
mizzou7016
in
Anxiety and Depression Support
7 months ago
Low testosterone is associated with extremely poor survival metrics, post-ADT.
These companion plots compare: (A) median survival times, (B) PSA doubling times, and (C) Time to PSA Failure for two different levels of testosterone: Low and Normal. The low testosterone has a median value of 162 ng/dL [120-236] and the average normal T = 680 ng/dL. The cohort is 58 men with unfavorable
These companion plots compare: (A) median survival times, (B) PSA doubling times, and (C) Time to PSA Failure for two different levels of testosterone: Low and Normal. The low testosterone has a median value of 162 ng/dL [120-236] and the average normal T = 680 ng/dL. The cohort is 58 men with unfavorable
janebob99
in
Prostate Cancer Network
5 months ago
Low Testosterone reduces Survival by a huge amount.
This plot compares prostate cancer specific mortality probability versus time for two different levels of testosterone: Low and Normal. The low testosterone has a median value of 162 ng/dL [120-236] and the average normal T = 680 ng/dL. The cohort is 58 men with unfavorable intermediate risk who underwent
This plot compares prostate cancer specific mortality probability versus time for two different levels of testosterone: Low and Normal. The low testosterone has a median value of 162 ng/dL [120-236] and the average normal T = 680 ng/dL. The cohort is 58 men with unfavorable intermediate risk who underwent
janebob99
in
Prostate Cancer Network
5 months ago
My own PSA values over time: 70% drop in just 3 months on Dutasteride and no ADT
Here are my own PSA values versus time plot. You can see there is an exponential rise in PSA starting at around 6/1/23, and doubling from PSA = 5 to 10 in about 8 months. My MRI at PSA = 10 showed a T3a tumor about 1.3 cm long (PIRADS 5). A subsequent targeted biopsy showed Gleason 3+4 in 4 cores,
Here are my own PSA values versus time plot. You can see there is an exponential rise in PSA starting at around 6/1/23, and doubling from PSA = 5 to 10 in about 8 months. My MRI at PSA = 10 showed a T3a tumor about 1.3 cm long (PIRADS 5). A subsequent targeted biopsy showed Gleason 3+4 in 4 cores,
janebob99
in
Prostate Cancer Network
5 months ago
Doubling Times and PSA acceleration - Part II
This is a more realistic schematic plot of PSA levels increasing over time at an ever faster rate (acceleration). What could cause this? My theory is that as the tumor grows, the number of androgen receptors (ARs) increases proportionally. That makes sense...more PCa cells inside a tumor...more ARs
This is a more realistic schematic plot of PSA levels increasing over time at an ever faster rate (acceleration). What could cause this? My theory is that as the tumor grows, the number of androgen receptors (ARs) increases proportionally. That makes sense...more PCa cells inside a tumor...more ARs
janebob99
in
Prostate Cancer Network
5 months ago
Preparing For Fistula Removal Surgery: What You Need To Know?
Fistula elimination surgical procedure is an extensive medical process that calls for cautious education to make certain the great feasible final results. Whether you're facing an anal rectal or urinary fistula understanding the steps you need to take before the surgery can help alleviate anxiety and
Fistula elimination surgical procedure is an extensive medical process that calls for cautious education to make certain the great feasible final results. Whether you're facing an anal rectal or urinary fistula understanding the steps you need to take before the surgery can help alleviate anxiety and
Dr_sucheta
in
Finding a Living Donor: From Home
11 months ago
Treatment Resistant Depression
I have had depression since my 20’s and likely in teens. I’m now 56 and my meds are no longer working like they once did. I’m going to be meeting with a clinic about other options ie: ECT etc. I’m very scared and anxious as this feels next level to me in my illness. Have you tried ECT and/or Esketamine
I have had depression since my 20’s and likely in teens. I’m now 56 and my meds are no longer working like they once did. I’m going to be meeting with a clinic about other options ie: ECT etc. I’m very scared and anxious as this feels next level to me in my illness. Have you tried ECT and/or Esketamine
Doubledog
in
Major Depressive Disorder (MDD) Support
7 months ago
Non metastasis castrate resistant
When you are on ADT and become Non metastatic Castrate resistant and your testosterone levels are below zero, what is the cancer feeding off to cause the PSA to still rise? Hoping for your replies so as to give me some understanding. Thank you.
When you are on ADT and become Non metastatic Castrate resistant and your testosterone levels are below zero, what is the cancer feeding off to cause the PSA to still rise? Hoping for your replies so as to give me some understanding. Thank you.
Sailameme
in
Advanced Prostate Cancer
5 months ago
Vitamin and mineral deficiencies/Thyroid dysfunction.. Chicken or Egg?
Before I spend my hard earned money on going to a private ENDO because the NHS is failing me I wanted to ask what you all thought about the problem of iron deficiency and vitamin D deficiency and how this relates to underactive thyroid . I read a lot here about how these vitamins should be optimal for
Before I spend my hard earned money on going to a private ENDO because the NHS is failing me I wanted to ask what you all thought about the problem of iron deficiency and vitamin D deficiency and how this relates to underactive thyroid . I read a lot here about how these vitamins should be optimal for
doingitfordad
in
Thyroid UK
10 months ago
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