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Early Results from Transdermal Estrogen PATCH trial
Here are some Early Results from the first year of the Transdermal Estrogen PATCH trial. References are available on their website at: http://patch.mrcctu.ucl.ac.uk. The cohort was men with High or Very High Risk prostate cancer. Stage T3 (73%) and Stage T4 (14%), baseline PSA = 35 ng/mL. The upper
Here are some Early Results from the first year of the Transdermal Estrogen PATCH trial. References are available on their website at: http://patch.mrcctu.ucl.ac.uk. The cohort was men with High or Very High Risk prostate cancer. Stage T3 (73%) and Stage T4 (14%), baseline PSA = 35 ng/mL. The upper
janebob99
in
Advanced Prostate Cancer
4 months ago
Early Results of Estrogen PATCH trial - 1
Here are some Early Results from the first year of the Transdermal Estrogen PATCH trial. References are available on their website at: http://patch.mrcctu.ucl.ac.uk. The cohort was men with High or Very High Risk prostate cancer. Stage T3 (73%) and Stage T4 (14%), baseline PSA = 35 ng/mL. The upper
Here are some Early Results from the first year of the Transdermal Estrogen PATCH trial. References are available on their website at: http://patch.mrcctu.ucl.ac.uk. The cohort was men with High or Very High Risk prostate cancer. Stage T3 (73%) and Stage T4 (14%), baseline PSA = 35 ng/mL. The upper
janebob99
in
Prostate Cancer Network
4 months ago
Results
Hi everyone I posted a couple of weeks ago and was advised to have bloods done. These are my results so hoping for further advice in supplementing or adjusting doseage. I currently take 50mcg Levothyroxine and 25mcg T3 daily. I also have B12 injections every 12wks. Latest B12 injection given day after
Hi everyone I posted a couple of weeks ago and was advised to have bloods done. These are my results so hoping for further advice in supplementing or adjusting doseage. I currently take 50mcg Levothyroxine and 25mcg T3 daily. I also have B12 injections every 12wks. Latest B12 injection given day after
Pixie50
in
Thyroid UK
4 months ago
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Medically induced menopause at 24
So I had surgery in July my pain ramped up post surgery and I'm not in excruciating pain daily some days bed bound I work and had 37 days of since km worried about my job they seem OK but its a worry still. I've exhausted alot of options eg. Pain relief and dienogest, doubling my pill for hormones ect
So I had surgery in July my pain ramped up post surgery and I'm not in excruciating pain daily some days bed bound I work and had 37 days of since km worried about my job they seem OK but its a worry still. I've exhausted alot of options eg. Pain relief and dienogest, doubling my pill for hormones ect
En89
in
Endometriosis UK
7 months ago
here again needing advice!!
Had a private blood test with medicheck a few weeks ago. Here are the results: TSH 1.23 mu/L Normal range 0.27-4.2 mu/L Thyroxine 16.9 pmol/L Normal FT4 levels 12-22 pmol/L Triiodothyronine 4.2 pmol:L Normal levels FT3 3.1-6.8 pmol/L I am still feeling really rubbish on 100 microgram levothyroxine
Had a private blood test with medicheck a few weeks ago. Here are the results: TSH 1.23 mu/L Normal range 0.27-4.2 mu/L Thyroxine 16.9 pmol/L Normal FT4 levels 12-22 pmol/L Triiodothyronine 4.2 pmol:L Normal levels FT3 3.1-6.8 pmol/L I am still feeling really rubbish on 100 microgram levothyroxine
Vorney
in
Thyroid UK
4 months ago
Day 7 in HRT protocol = equivalent to what day in Natural cycle?
Hello my dear warriors, My clinic in Spain has recommended to go for a natural cycle rather than a HRT one this time. However my immune medicine is prescribed by the reproductive immunologist and to his protocol he has written : start Clexane and Prednisolone on day 7 of HRT. The nurses in his clinic
Hello my dear warriors, My clinic in Spain has recommended to go for a natural cycle rather than a HRT one this time. However my immune medicine is prescribed by the reproductive immunologist and to his protocol he has written : start Clexane and Prednisolone on day 7 of HRT. The nurses in his clinic
ValaI
in
Fertility Network UK
4 months ago
Estrogen ADT vs Lupron ADT
Here's a chart showing % of men who have a given condition, comparing Estrogen ADT versus Lupron ADT. There's big reduction in hot flashes, and improvements in libido, when taking supplemental Estrogen. Estrogen increases gynecomastia (enlarged breasts), however. Bob
Here's a chart showing % of men who have a given condition, comparing Estrogen ADT versus Lupron ADT. There's big reduction in hot flashes, and improvements in libido, when taking supplemental Estrogen. Estrogen increases gynecomastia (enlarged breasts), however. Bob
janebob99
in
Prostate Cancer Network
4 months ago
Just started Eltroxin
Hi everyone and thanks for reading. After having to go private I have been prescribed T4 50 mg. my thyroid has been struggling almost 3 years and iv suffered a lot with no headway from GP and an Endo. My results have been fluctuating. Latest TSH 3.22 (0.27-4.20) FT3 4.1 (3.1-6.8) FT4 11.5 (
Hi everyone and thanks for reading. After having to go private I have been prescribed T4 50 mg. my thyroid has been struggling almost 3 years and iv suffered a lot with no headway from GP and an Endo. My results have been fluctuating. Latest TSH 3.22 (0.27-4.20) FT3 4.1 (3.1-6.8) FT4 11.5 (
FoxyTed
in
Thyroid UK
4 months ago
Silly Questions??
1) Why do some advanced prostate cancer patients get offered "vacations", from ADT and others don't? 2) Why do some advanced prostate cancer patients have NO Chemo, and go directly to ADT + Abiraterone+Prednisone, while others begin treatment with chemo and radiation? What are the deciding criteria
1) Why do some advanced prostate cancer patients get offered "vacations", from ADT and others don't? 2) Why do some advanced prostate cancer patients have NO Chemo, and go directly to ADT + Abiraterone+Prednisone, while others begin treatment with chemo and radiation? What are the deciding criteria
TommyCarz2
in
Advanced Prostate Cancer
4 months ago
Low cortisol, low T3 results-pls advise, terrified I’ll have to stop work as just exhausted
hi.. I’m on levo 100mg for at least a year now, been diagnosed hypothyroid for 2 years I think. . Had these tests done privately dec 2023. Previous test a year before saw lower TSH - seemed to have climbed up, and higher T3 than before. I haven’t shown to GP yet- partly cos just depressed and exhausted
hi.. I’m on levo 100mg for at least a year now, been diagnosed hypothyroid for 2 years I think. . Had these tests done privately dec 2023. Previous test a year before saw lower TSH - seemed to have climbed up, and higher T3 than before. I haven’t shown to GP yet- partly cos just depressed and exhausted
Midlake
in
Thyroid UK
4 months ago
Allergic reaction to Doxil, my first ever chemo infusion
Hi everyone, Has anyone experienced an allergic reaction to Doxil? Almost three years ago, I was diagnosed with stage 4 MBC. After being on hormone therapy for over two years, mostly IBrance and Letrozole, and then oral chemo for six months, my most recent petscan showed the cancer is still spreading
Hi everyone, Has anyone experienced an allergic reaction to Doxil? Almost three years ago, I was diagnosed with stage 4 MBC. After being on hormone therapy for over two years, mostly IBrance and Letrozole, and then oral chemo for six months, my most recent petscan showed the cancer is still spreading
penpen18
in
SHARE Metastatic Breast Cancer
4 months ago
Ectopics - one after the other. So scared
Hi everyone. I posted on this forum a few years ago and everyone was so helpful. I wonder if anyone could offer some advice/reassurance? Quick back sorry. I had an SVT around 2.5 years ago and ended up in hospital. Had all tests and nothing wrong. Was put on 1.25mg Bisoprolol which made me horribly
Hi everyone. I posted on this forum a few years ago and everyone was so helpful. I wonder if anyone could offer some advice/reassurance? Quick back sorry. I had an SVT around 2.5 years ago and ended up in hospital. Had all tests and nothing wrong. Was put on 1.25mg Bisoprolol which made me horribly
mummyofspot
in
British Heart Foundation
4 months ago
Any suggestions please.
Hello. I wonder if you would be kind enough to give me your views on my latest results please. I currently take 100mcg thyroxine at bedtime. My GP withdrew my T3 ( 5mcg) around 5 years ago. Apparently it doesn't work and was too expensive. I feel dreadful. I'm underweight with a BMI of 18 and on top
Hello. I wonder if you would be kind enough to give me your views on my latest results please. I currently take 100mcg thyroxine at bedtime. My GP withdrew my T3 ( 5mcg) around 5 years ago. Apparently it doesn't work and was too expensive. I feel dreadful. I'm underweight with a BMI of 18 and on top
andreab
in
Thyroid UK
4 months ago
No Osteoporosis with Estrogen Patch Therapy
These plots compare results from the Phase-II randomized trial (PATCH) comparing estrogen patch therapy to Lupron ADT. These plots show that Lupron ADT causes bone loss, while estrogen patch therapy has either no bone loss or increased bone mineral density (BMD) over time. Bob
These plots compare results from the Phase-II randomized trial (PATCH) comparing estrogen patch therapy to Lupron ADT. These plots show that Lupron ADT causes bone loss, while estrogen patch therapy has either no bone loss or increased bone mineral density (BMD) over time. Bob
janebob99
in
Prostate Cancer Network
4 months ago
Castration by Estrogen Patch
This plot shows a dramatic decrease in testosterone and PSA after starting estrogen patch therapy, indicating that transdermal estrogen (TDE) therapy effectively castrates men, and with fewer side effects than Lupron ADT.
This plot shows a dramatic decrease in testosterone and PSA after starting estrogen patch therapy, indicating that transdermal estrogen (TDE) therapy effectively castrates men, and with fewer side effects than Lupron ADT.
janebob99
in
Prostate Cancer Network
4 months ago
Advanced prostate cancer
Hey there,I'm just seeing if I can get any insight on this from anyone living this now.My father is 70 and was recently diagnosed with prostate cancer and there was a spot on his rob as well from it.I don't know what stage it is but he is currently on hormone therapy and gets injections every 3 months
Hey there,I'm just seeing if I can get any insight on this from anyone living this now.My father is 70 and was recently diagnosed with prostate cancer and there was a spot on his rob as well from it.I don't know what stage it is but he is currently on hormone therapy and gets injections every 3 months
Catdog1111
in
Advanced Prostate Cancer
4 months ago
If PSA is Suppressed by Doublet ADT, Will Salvage IMRT Cause a PSA Rise?
Hello everyone, My husband is nearing completion of his extended pelvic salvage IMRT with boost to retrocaval lymph nodes. His radiation oncologist said it may take several months before the psa calms down, so he would like to see him in July. My question is that, since he is already undetectable due
Hello everyone, My husband is nearing completion of his extended pelvic salvage IMRT with boost to retrocaval lymph nodes. His radiation oncologist said it may take several months before the psa calms down, so he would like to see him in July. My question is that, since he is already undetectable due
103532
in
Advanced Prostate Cancer
3 months ago
Transdermal estrogen/estradiol as monotherapy for Prostate Cancer
Does anyone know of recent studies, clinical trials or Standard of Care (SoC) protocols using or studying estrogen gels, sprays, ointments or patches as hormone therapy for Prostate Cancer, particularly micrometastatic cancer that has not spread beyond the pelvic region? I am in discussions with my
Does anyone know of recent studies, clinical trials or Standard of Care (SoC) protocols using or studying estrogen gels, sprays, ointments or patches as hormone therapy for Prostate Cancer, particularly micrometastatic cancer that has not spread beyond the pelvic region? I am in discussions with my
Lost_Sheep
in
Prostate Cancer Network
4 months ago
The paradigm has shifted - castrate resistance.
It now appears that I’ve entered the land of castrate resistance and further ADT vacations are no longer in the plan. My T level recovered much more quickly during the last vacation than during previous vacations, and my PSA rose correspondingly. At 4 months my T level was 325 and my PSA was 4. Another
It now appears that I’ve entered the land of castrate resistance and further ADT vacations are no longer in the plan. My T level recovered much more quickly during the last vacation than during previous vacations, and my PSA rose correspondingly. At 4 months my T level was 325 and my PSA was 4. Another
fireandice123
in
Advanced Prostate Cancer
4 months ago
Life Expectancy
My father was diagnosed with advanced prostate cancer four years ago. Initially, he underwent radiation for a few spots on his ribs and immediately began ADT/Xtandi treatment for two years. His PSA dropped to 0.001, prompting his medical oncologist to recommend a medication vacation. For two years, he
My father was diagnosed with advanced prostate cancer four years ago. Initially, he underwent radiation for a few spots on his ribs and immediately began ADT/Xtandi treatment for two years. His PSA dropped to 0.001, prompting his medical oncologist to recommend a medication vacation. For two years, he
godhelpus
in
Advanced Prostate Cancer
4 months ago
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