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Rasagiline – Second-Generation MAO-B Inhibitor for the Treatment of Parkinson’s Disease
According to the below article, it slows down the disease progression https://www.clinicaltrialsarena.com/projects/
rasagiline
-parkinsons-disease/
According to the below article, it slows down the disease progression https://www.clinicaltrialsarena.com/projects/
rasagiline
-parkinsons-disease/
Farooqji
in
Cure Parkinson's
1 year ago
Rytary update
If I need it, I take 1/2-1 C/L IR to cover until 8 am. 8am 2x145 plus 1x95 plus
Rasagiline
1pm Same, plus 1/2 C/L IR, around 2:30. It does help with the slump.
If I need it, I take 1/2-1 C/L IR to cover until 8 am. 8am 2x145 plus 1x95 plus
Rasagiline
1pm Same, plus 1/2 C/L IR, around 2:30. It does help with the slump.
rebtar
in
Cure Parkinson's
1 year ago
Anyone have differerent effectiveness for same meds but manufacturer?
I've spent 3 months on one brand of foil packed
rasagiline
with modest improvements however a week ago I got a different brand that was just a bottle of pills. Since then I've noticed my symptoms getting worse.
I've spent 3 months on one brand of foil packed
rasagiline
with modest improvements however a week ago I got a different brand that was just a bottle of pills. Since then I've noticed my symptoms getting worse.
Jefferami
in
Cure Parkinson's
9 months ago
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Need Guidance Transitioning from Siment to Mununa
s 1) do I take out the
Rasagiline
now when I’m just starting replacing 1/2 dose each week will that affect the Siment? 2) is the doctors protocol correct? And what about dosage is it equivalent?
s 1) do I take out the
Rasagiline
now when I’m just starting replacing 1/2 dose each week will that affect the Siment? 2) is the doctors protocol correct? And what about dosage is it equivalent?
Joy_gitt
in
Cure Parkinson's
1 year ago
Rasagiline: The Neuroprotective Activities of the Novel Multi-Target Iron-Chelators in Models of Alzheimer’s Disease, ALS and Aging
(Azilect®) [125] (Figure 2) thus inheriting some of their neuroprotective/neurorestorative properties and have additional neurorestorative activity associated with the introduction of a propargylamine monoamine oxidase (MAO) inhibitor moiety of anti-Parkinson drug
rasagiline
(Azilect®).
(Azilect®) [125] (Figure 2) thus inheriting some of their neuroprotective/neurorestorative properties and have additional neurorestorative activity associated with the introduction of a propargylamine monoamine oxidase (MAO) inhibitor moiety of anti-Parkinson drug
rasagiline
(Azilect®).
Hidden
in
Cure Parkinson's
1 year ago
Pharma Two B to Present Additional Positive Results from P2B001 Phase 3 Trial at 2023 American Academy of Neurology Annual Meeting
Results showed P2B001, a once-daily fixed-dose combination of low dose pramipexole and low dose
rasagiline
, showed comparable efficacy to marketed optimally titrated pramipexole, with significantly reduced sleep-related and dopaminergic side effectsData analysis also confirmed patients treated with P2B001
Results showed P2B001, a once-daily fixed-dose combination of low dose pramipexole and low dose
rasagiline
, showed comparable efficacy to marketed optimally titrated pramipexole, with significantly reduced sleep-related and dopaminergic side effectsData analysis also confirmed patients treated with P2B001
Farooqji
in
Cure Parkinson's
1 year ago
Levodopa not helping
My HwP was diagnosed 7 years ago at age 62 - mild right-sided tremor, absent arm swing, problems with handwriting - and he started
rasagiline
about 3 years ago which he continues to take.
My HwP was diagnosed 7 years ago at age 62 - mild right-sided tremor, absent arm swing, problems with handwriting - and he started
rasagiline
about 3 years ago which he continues to take.
goldengrove
in
Cure Parkinson's
8 months ago
helped needed on how to treat internal tremors in arms and legs
I was diagnosed with PD over 3 years ago and prescribed
Rasagiline
and Madopar. Sorted RLS with TruNiagen. Nicotinamide Riboside Sorted most PD symptoms with B1 sublingual. Eg balance, arm swing, smile, energy etc.
I was diagnosed with PD over 3 years ago and prescribed
Rasagiline
and Madopar. Sorted RLS with TruNiagen. Nicotinamide Riboside Sorted most PD symptoms with B1 sublingual. Eg balance, arm swing, smile, energy etc.
Windermere1
in
Cure Parkinson's
1 year ago
MAOI for depression in Parkinson’s
Recently started
Rasagiline
which I’ve been on for about a month but not feeling anything from it. Next suggestion from my neuro psychiatrist is moclobimide but I read it doesn’t increase dopamine which I believe is fundamental in my depression given that it tied into Parkinson’s.
Recently started
Rasagiline
which I’ve been on for about a month but not feeling anything from it. Next suggestion from my neuro psychiatrist is moclobimide but I read it doesn’t increase dopamine which I believe is fundamental in my depression given that it tied into Parkinson’s.
Schofield81
in
Cure Parkinson's
1 year ago
Trial if rasagiline can reduce the progression from idiopathic REM sleep behavior disorder (RBD) to Parkinsons
https://clinicaltrials.gov/ct2/show/NCT05611372 To investigate whether a year of
rasagiline
may reduce the progression from idiopathic REM sleep behavior disorder (RBD) to Parkinson's disease (PD). https://twitter.com/ScienceofPD/status/1594676840001867779
https://clinicaltrials.gov/ct2/show/NCT05611372 To investigate whether a year of
rasagiline
may reduce the progression from idiopathic REM sleep behavior disorder (RBD) to Parkinson's disease (PD). https://twitter.com/ScienceofPD/status/1594676840001867779
Hidden
in
Cure Parkinson's
2 years ago
two unrelated topics - Viraball & Mucana/Rasagiline
– Looking into starting Mucana (also for hand tremor control) and had read (link below) that one should go off
Rasagiline
first. I am not on C/L yet, but will likely at some point. My motion specialist said it was fine to be on
Rasagiline
and C/L at the same time.
– Looking into starting Mucana (also for hand tremor control) and had read (link below) that one should go off
Rasagiline
first. I am not on C/L yet, but will likely at some point. My motion specialist said it was fine to be on
Rasagiline
and C/L at the same time.
mh1214
in
Cure Parkinson's
2 years ago
Long-acting injectable in situ gel of rasagiline: a patented product development
https://pubmed.ncbi.nlm.nih.gov/36575353/
https://pubmed.ncbi.nlm.nih.gov/36575353/
Hidden
in
Cure Parkinson's
2 years ago
Vagal Nerve Stimulation (tVNS) Research Summary
treatments of FOG remain great challenges for clinicians and researchers. 19 In the risk factor section, gait disorders, PIGD phenotype, lower striatal DAT uptake were found to be independent risk factors of FOG with consistent evidence. 19 Two drugs that showed promise for FOG include istradefylline and
rasagiline
treatments of FOG remain great challenges for clinicians and researchers. 19 In the risk factor section, gait disorders, PIGD phenotype, lower striatal DAT uptake were found to be independent risk factors of FOG with consistent evidence. 19 Two drugs that showed promise for FOG include istradefylline and
rasagiline
House2
in
Cure Parkinson's
1 year ago
Does anyone on Azilect/ Rasagiline experienced slow down of progression of PD?
Does anyone benefit from this?Thanks
Does anyone benefit from this?Thanks
TL500
in
Cure Parkinson's
2 years ago
Medications, supplements and other therapies used in Parkinsons
istradefylline Exercise Estrogen Fish oil Flavanoids GABA Ginkgo Biloba Extract Glutathione GLP-1 (Victoza) Hydrogen water Ibuprofen Infrared light therapy K2 Kelp Lactoferrin Leucitine Lecithin Licorice Luteolin L-Theanine Lycopene Magnesium Mannitol MAO-B inhibitors Selegiline,
Rasagiline
istradefylline Exercise Estrogen Fish oil Flavanoids GABA Ginkgo Biloba Extract Glutathione GLP-1 (Victoza) Hydrogen water Ibuprofen Infrared light therapy K2 Kelp Lactoferrin Leucitine Lecithin Licorice Luteolin L-Theanine Lycopene Magnesium Mannitol MAO-B inhibitors Selegiline,
Rasagiline
healthyheart7
in
Cure Parkinson's
2 years ago
New Phase 3 Trial Data Back P2B001 as Therapy for Early Parkinson’s
It contains low doses of pramipexole (0.6 mg) and
rasagiline
(0.75 mg). Both compounds are approved therapies for Parkinson’s — marketed as Mirapex (pramipexole) and Azilect (
rasagiline
). The low doses used in P2B001 are not currently available on the market.
It contains low doses of pramipexole (0.6 mg) and
rasagiline
(0.75 mg). Both compounds are approved therapies for Parkinson’s — marketed as Mirapex (pramipexole) and Azilect (
rasagiline
). The low doses used in P2B001 are not currently available on the market.
Farooqji
in
Cure Parkinson's
2 years ago
Wake up dormant dopaminergic neurons to reverse Parkinson’s disease
Rasagiline
(Azilect®) Available Doses: 0.5 mg, 1 mg doses. ... Safinamide (Xadago) Available Doses: 200 mg.
Rasagiline
(Azilect®) Available Doses: 0.5 mg, 1 mg doses. ... Safinamide (Xadago) Available Doses: 200 mg.
delboy381
in
Cure Parkinson's
2 years ago
Fatigue and worsened depression following COVID-19 in a Parkinson’s patient
Hey people, I wonder if any of you can share some advice, ideas or insights here: My father, who’s 76 years old, suffers from Parkinson’s for the last 1.5 years and is treated with
Rasagiline
(Azilect). He recently had COVID-19.
Hey people, I wonder if any of you can share some advice, ideas or insights here: My father, who’s 76 years old, suffers from Parkinson’s for the last 1.5 years and is treated with
Rasagiline
(Azilect). He recently had COVID-19.
omers
in
Cure Parkinson's
2 years ago
Nausea with Azilect (rasagiline)
Hwp started Azilect a week ago and is quite nauseous from the med. Does the nausea get better with time? Have you found ways to mitigate this side effect that worked for you? Thank you in advance!
Hwp started Azilect a week ago and is quite nauseous from the med. Does the nausea get better with time? Have you found ways to mitigate this side effect that worked for you? Thank you in advance!
Snoopy5
in
Cure Parkinson's
2 years ago
Short snap in head
DH is still refusing to take
Rasagiline
and we are only 6 months into Parkinson’s DX, although it was mentioned that it could be Parkinson’s Plus. DH mentioned that he has had a short pain in his head, says it is like a rubber band snapping.
DH is still refusing to take
Rasagiline
and we are only 6 months into Parkinson’s DX, although it was mentioned that it could be Parkinson’s Plus. DH mentioned that he has had a short pain in his head, says it is like a rubber band snapping.
TigerGirl79
in
Multiple System Atrophy Trust
2 years ago
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