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Assessing the Benefit of CAR T-cell Therapies for mCRPC
A first-in-human phase 1 trial (NCT03873805) investigated the safety and bioactivity of prostate stem cell antigen-directed CAR T cells for patients with metastatic castration-resistant prostate cancer. CancerNetwork® spoke with Saul Priceman, PhD, associate professor and associate director of the
A first-in-human phase 1 trial (NCT03873805) investigated the safety and bioactivity of prostate stem cell antigen-directed CAR T cells for patients with metastatic castration-resistant prostate cancer. CancerNetwork® spoke with Saul Priceman, PhD, associate professor and associate director of the
God_Loves_Me
in
Advanced Prostate Cancer
1 month ago
NICE early value assessment on robot-assisted surgery
Good afternoon everyone, We have been contacted by the National Institute of Health and Care Excellence (NICE) as they are currently undertaking an early value assessment on robot-assisted surgery for soft tissue procedures. We have been invited to make a submission as part of this assessment. It
Good afternoon everyone, We have been contacted by the National Institute of Health and Care Excellence (NICE) as they are currently undertaking an early value assessment on robot-assisted surgery for soft tissue procedures. We have been invited to make a submission as part of this assessment. It
OvacomeSupport
My Ovacome Team
in
My Ovacome
1 month ago
What Now?
I have been out of the hospital for about 3 days after VAT surgery. I am taking a medication and I feel nausea all the time, and even the thought of food makes me want to vomit. Is this normal? I am taking paracitomol, ibuprofin, dicloxacillin and another medication for the cough. I dont feel too
I have been out of the hospital for about 3 days after VAT surgery. I am taking a medication and I feel nausea all the time, and even the thought of food makes me want to vomit. Is this normal? I am taking paracitomol, ibuprofin, dicloxacillin and another medication for the cough. I dont feel too
VATpatient
in
Lung Cancer Support
1 month ago
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My 80 year-old dad with MPCa, broke his leg and now seems to be giving up. Advice on best anti-anxiety meds desperately needed.
Dear PC family As you will see from my profile my dad in England has been on his prostate cancer journey for five years. He was doing well until March, still actively farming though fatigued, and was due to start Radium 223 in April. Sadly, he broke his leg on March 12 in a fall, was put in a full-leg
Dear PC family As you will see from my profile my dad in England has been on his prostate cancer journey for five years. He was doing well until March, still actively farming though fatigued, and was due to start Radium 223 in April. Sadly, he broke his leg on March 12 in a fall, was put in a full-leg
Lemonpower
in
Advanced Prostate Cancer
1 month ago
3mm nodule on Cardiac CT scan
On a Cardiac CT scan for my husband his internist (Not from MSK) found a nodule. This is what the impression said: "Stable 3 mm nodule in the left upper lobe, probably an impacted small airway or benign lymph node. Recommend follow-up per clinical/oncologic protocol in this patient with reported prostate
On a Cardiac CT scan for my husband his internist (Not from MSK) found a nodule. This is what the impression said: "Stable 3 mm nodule in the left upper lobe, probably an impacted small airway or benign lymph node. Recommend follow-up per clinical/oncologic protocol in this patient with reported prostate
SherryKahn
in
Advanced Prostate Cancer
2 months ago
I think we knew this - PSMA-Pet superior to MRI
PSMA PET Beats MRI in Prostate Cancer Staging Study https://www.medpagetoday.com/hematologyoncology/prostatecancer/110931 The article is basically about using PSMA-PET to plan surgical procedures more accurately, but the study has a secondary result in - that PSMA-PET found a very significant percentage
PSMA PET Beats MRI in Prostate Cancer Staging Study https://www.medpagetoday.com/hematologyoncology/prostatecancer/110931 The article is basically about using PSMA-PET to plan surgical procedures more accurately, but the study has a secondary result in - that PSMA-PET found a very significant percentage
Don_1213
in
Prostate Cancer Network
2 months ago
radiotherapy
Hi all. My husband is scheduled to have radiotherapy on Wednesday. This will hopefully stop, or at least slow down the cancer growing in his liver. He will also have radiotherapy on a hip bone which has started to cause some pain. Hopefully he will get some relief from this. I think that for now
Hi all. My husband is scheduled to have radiotherapy on Wednesday. This will hopefully stop, or at least slow down the cancer growing in his liver. He will also have radiotherapy on a hip bone which has started to cause some pain. Hopefully he will get some relief from this. I think that for now
Believeit
in
Advanced Prostate Cancer
2 months ago
Interferon
Hi everyone im on 90mg interferon every second week since Feb this year platelets were 1110 came dwn to 916 quick enough but haven't really moved dwn much since actually they went up again and now they are 876 is this the way for any of ye as it seems fairly slow to me even though my hematologist
Hi everyone im on 90mg interferon every second week since Feb this year platelets were 1110 came dwn to 916 quick enough but haven't really moved dwn much since actually they went up again and now they are 876 is this the way for any of ye as it seems fairly slow to me even though my hematologist
VTAR24
in
MPN Voice
2 months ago
struggling after surgery
Hi I had debulking surgery 25th June, good outcome all visible cancer removed which is great news, Post surgery it’s been so tough. Really sick with green yuk , then tube up my nose into stomach to drain off , then CT scan with contrast, vein blow have way through die goes into wrist. I have clots on
Hi I had debulking surgery 25th June, good outcome all visible cancer removed which is great news, Post surgery it’s been so tough. Really sick with green yuk , then tube up my nose into stomach to drain off , then CT scan with contrast, vein blow have way through die goes into wrist. I have clots on
Sunsetime
in
My Ovacome
2 months ago
State 3 Breast Cancer
I discovered a lump in my breast early in April. Was sent for an ultrasound which was very suspicious. Biopsy revealed cancer. Oncololgist confirmed stage 3 metastic breast cancer. She put me on Anastrozole and when final tests came in started me on Ibrance 100. After two weeks my wbc was very low
I discovered a lump in my breast early in April. Was sent for an ultrasound which was very suspicious. Biopsy revealed cancer. Oncololgist confirmed stage 3 metastic breast cancer. She put me on Anastrozole and when final tests came in started me on Ibrance 100. After two weeks my wbc was very low
catfreddie
in
SHARE Metastatic Breast Cancer
2 months ago
Tough decision
I've been on AS for 5 years with Moffit had 3 biopsy's all gleason 6 except a second opinion on my first one 2 cores where changed to a 7. PSA has bounced around but highest was 6.43 this April last week 5.13. Because of my recent MRI shows growth on the lesion and possible extracasular extension. So
I've been on AS for 5 years with Moffit had 3 biopsy's all gleason 6 except a second opinion on my first one 2 cores where changed to a 7. PSA has bounced around but highest was 6.43 this April last week 5.13. Because of my recent MRI shows growth on the lesion and possible extracasular extension. So
twoodogs
in
Prostate Cancer Network
2 months ago
Has anyone had breast cancer Mets in para aortic lymph nodes?
after a solitary bone met which has been managed for a few years, I now have breast cancer Mets in my para aortic lymph nodes. I’m on Fulvestrant.
after a solitary bone met which has been managed for a few years, I now have breast cancer Mets in my para aortic lymph nodes. I’m on Fulvestrant.
Thredbo2
in
SHARE Metastatic Breast Cancer
2 months ago
Has anyone had breast cancer Mets in para aortic lymph nodes?
after a solitary bone met which has been managed for a few years, I now have breast cancer Mets in my para aortic lymph nodes. I’m on Fulvestrant.
after a solitary bone met which has been managed for a few years, I now have breast cancer Mets in my para aortic lymph nodes. I’m on Fulvestrant.
Thredbo2
in
SHARE Metastatic Breast Cancer
2 months ago
LVV Update
Hello, just getting back with the latest on what appears to be a huge LVV flare. Had the PET Scan on Thursday and doc called yesterday. I have the scan but can’t really read it other than to see that there is no “hyper metabolic intra cranial lesion” or “FDG avid cervical or supraclavicular lymphadenopathy
Hello, just getting back with the latest on what appears to be a huge LVV flare. Had the PET Scan on Thursday and doc called yesterday. I have the scan but can’t really read it other than to see that there is no “hyper metabolic intra cranial lesion” or “FDG avid cervical or supraclavicular lymphadenopathy
LemonZest11
in
PMRGCAuk
2 months ago
A recent MRI of the Abdomen
6/28/24- I am about to start calquence. I would appreciate your words of encouragement and advice. Follow-up mLeft upper pole 1.8 cm hypoenhancing solid renal lesion concerning for renal cell carcinoma, papillary subtype. Less likely differential of lymphomatous lesion. Innumerable additional
6/28/24- I am about to start calquence. I would appreciate your words of encouragement and advice. Follow-up mLeft upper pole 1.8 cm hypoenhancing solid renal lesion concerning for renal cell carcinoma, papillary subtype. Less likely differential of lymphomatous lesion. Innumerable additional
bagelstreet225
in
CLL Support
2 months ago
CAR T-Cell Therapy Demonstrates Promising Results for mCRPC
A total of 14 patients were treated between August 2019 and July 2022. The median patient age was 62 in dose level 1 (DL1), 70 for dose level 2 (DL2), and 69 for dose level 3 (DL3). The baseline prostate-specific antigen (PSA) ranged from 16.5 ng/mL to 235.3 ng/mL. Primary end points were safety and
A total of 14 patients were treated between August 2019 and July 2022. The median patient age was 62 in dose level 1 (DL1), 70 for dose level 2 (DL2), and 69 for dose level 3 (DL3). The baseline prostate-specific antigen (PSA) ranged from 16.5 ng/mL to 235.3 ng/mL. Primary end points were safety and
God_Loves_Me
in
Advanced Prostate Cancer
2 months ago
Xeloda neck pain
On first week xeloda and I get severe neck and face pain once a day..I take a klonpin and tylenol and relieved in half hour..I don't know if anyone else has it.ROX
On first week xeloda and I get severe neck and face pain once a day..I take a klonpin and tylenol and relieved in half hour..I don't know if anyone else has it.ROX
Mcangel11
in
SHARE Metastatic Breast Cancer
2 months ago
surgery
well it’s been a while since I posted my fellow warriors Started having hip issues a couple of months ago. Did a Ct and MRI as well as X-rays. Found that the ball was gone off my left hip , then on closer inspection found that the right hip the cancer had eaten all the way thru the upper femur ?
well it’s been a while since I posted my fellow warriors Started having hip issues a couple of months ago. Did a Ct and MRI as well as X-rays. Found that the ball was gone off my left hip , then on closer inspection found that the right hip the cancer had eaten all the way thru the upper femur ?
larry_dammit
in
Advanced Prostate Cancer
2 months ago
Wondering what to do
Hello I have not posted for a while but I wondered if any had any thoughts to help me with my dilemma. I have had 18 rounds of chemo and rucaparib all of which have been successful for a while. I also had surgery in 2020 when I was diagnosed. My last lot of single carbo chemo have me a stable few months
Hello I have not posted for a while but I wondered if any had any thoughts to help me with my dilemma. I have had 18 rounds of chemo and rucaparib all of which have been successful for a while. I also had surgery in 2020 when I was diagnosed. My last lot of single carbo chemo have me a stable few months
BadgerBright
in
My Ovacome
2 months ago
Shirley
I MBC that had spread to bones now found two small spots on lungs. I was taking ansezole for estrogen blocker and venezico .I am ER statuses positive , HER2 negative. They say I have mutation on my cancer an wants me take a treatment PIQKAY and Fulvestrant. I am very nervous taking these. ANYONE
I MBC that had spread to bones now found two small spots on lungs. I was taking ansezole for estrogen blocker and venezico .I am ER statuses positive , HER2 negative. They say I have mutation on my cancer an wants me take a treatment PIQKAY and Fulvestrant. I am very nervous taking these. ANYONE
Moonfry
in
SHARE Metastatic Breast Cancer
2 months ago
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