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Antidepressants
Hi all, Increased anxiety has become one of my worst symptoms of B12 deficiency and (possible*) PA. I’m on 4 weekly B12 injections (Hydrocobalamin 1mg) on the NHS but I’ve not noticed any improvements so far. I’ve had the 6 loading doses and 2 further injections so far. I’m taking D3/K2 (3000iu/100ug
Hi all, Increased anxiety has become one of my worst symptoms of B12 deficiency and (possible*) PA. I’m on 4 weekly B12 injections (Hydrocobalamin 1mg) on the NHS but I’ve not noticed any improvements so far. I’ve had the 6 loading doses and 2 further injections so far. I’m taking D3/K2 (3000iu/100ug
Pa234aw
in
Pernicious Anaemia Society
4 months ago
Genetic therapy: for solid malignancy hopefully soon
ok, I post them also because they are fellow Italians! But the platform is very promising even if clinical use has been approved only for glioma and glioblastoma at the moment. But there are clinical trials going on for solid tumors, prostate included. https://www.genenta.com/wp-content/uploads/2021
ok, I post them also because they are fellow Italians! But the platform is very promising even if clinical use has been approved only for glioma and glioblastoma at the moment. But there are clinical trials going on for solid tumors, prostate included. https://www.genenta.com/wp-content/uploads/2021
Maxone73
in
Advanced Prostate Cancer
7 months ago
Lupus or another Autoimmune Disease?
I’m 50 yr old female with issues, RLS, Hashimotos, Autoimmune Atrophic Chronic Gastritis, intestinal Metaplasia, Iron Deficiency Anemia w/transfusions, B12 deficiency, and now this horrible hip and joint pain. I know if you have one Autoimmune Disease you’re likely to have more. I’ve had a full work
I’m 50 yr old female with issues, RLS, Hashimotos, Autoimmune Atrophic Chronic Gastritis, intestinal Metaplasia, Iron Deficiency Anemia w/transfusions, B12 deficiency, and now this horrible hip and joint pain. I know if you have one Autoimmune Disease you’re likely to have more. I’ve had a full work
Milescircus
in
LUPUS UK
3 months ago
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blood tests
hi lovely people, I was wondering if you could give me any advice. I’m relatively new to all of this and I’ve had a very bad experience at my last hospital. I was misdiagnosed most of last year with Complex Regional Pain disease. My rheumatologist wouldn’t even consider an autoimmune disease. Anyway
hi lovely people, I was wondering if you could give me any advice. I’m relatively new to all of this and I’ve had a very bad experience at my last hospital. I was misdiagnosed most of last year with Complex Regional Pain disease. My rheumatologist wouldn’t even consider an autoimmune disease. Anyway
Tonkie
in
LUPUS UK
3 months ago
Mastectomy after 7 years of MBC
I have had MBC for 7 years still on my first line of treatment (Ibrance/Letrozole) my PET scan in September showed the tumor in my breast has increased in size and the cancer has gone into a lymph node under my armpit. Today I met with a surgeon and will have a double mastectomy in early January. My
I have had MBC for 7 years still on my first line of treatment (Ibrance/Letrozole) my PET scan in September showed the tumor in my breast has increased in size and the cancer has gone into a lymph node under my armpit. Today I met with a surgeon and will have a double mastectomy in early January. My
Gmaoftriplets
in
SHARE Metastatic Breast Cancer
7 months ago
Incomplete Evacuation and Diarrhoea
Hi there, 26yo female suffering with debilitating daily morning diarrhoea followed by incomplete evacuation, where it feels like my muscles just stop moving and there's an obstruction. I was diagnosed with IBS in 2020 when symptoms started, tried fodmap diet, mebeverine, linseeds, anitbiotics for suspected
Hi there, 26yo female suffering with debilitating daily morning diarrhoea followed by incomplete evacuation, where it feels like my muscles just stop moving and there's an obstruction. I was diagnosed with IBS in 2020 when symptoms started, tried fodmap diet, mebeverine, linseeds, anitbiotics for suspected
UnroolyGut
in
IBS Network
4 months ago
Had a 5 day transfer 14/2 boobs no longer hurt does this mean it’s failed?
hi guys I’m 3 days post transfer and my boobs have stopped hurting and I feel less bloated does this mean it’s not worked . I had a 5 day blasocyst transferred Wednesday 14th and test is due next Friday . All my back ache bloating and constipation is all fading now .
hi guys I’m 3 days post transfer and my boobs have stopped hurting and I feel less bloated does this mean it’s not worked . I had a 5 day blasocyst transferred Wednesday 14th and test is due next Friday . All my back ache bloating and constipation is all fading now .
Lemons1986
in
Fertility Network UK
4 months ago
facial pain after suro
hi all I had surgery 15th June 2022 to remove a large tumour. I have had a few problems after including facial paralysis on my right side after but it literally normal now. I had a lot of injections. My right eye is completely dry and they did a nerve transplant to try and correct this. So have been
hi all I had surgery 15th June 2022 to remove a large tumour. I have had a few problems after including facial paralysis on my right side after but it literally normal now. I had a lot of injections. My right eye is completely dry and they did a nerve transplant to try and correct this. So have been
Elephant0
in
Acoustic Neuroma Support
7 months ago
Help Needed! Have I got Pernicious Anaemia?
I hope this isn't too long and/or too boring. I suspect I have PA but as with a lot of people here, no-one seems to take B12 deficiency seriously. I also have hypothyroidism so as my symptoms got increasingly worse over the past few years, I blamed my thyroid - the two conditions have many symptoms
I hope this isn't too long and/or too boring. I suspect I have PA but as with a lot of people here, no-one seems to take B12 deficiency seriously. I also have hypothyroidism so as my symptoms got increasingly worse over the past few years, I blamed my thyroid - the two conditions have many symptoms
Grannypants
in
Pernicious Anaemia Society
4 months ago
Lynparza for bone/liver mets - success?
Hello! Unfortunately, my PET scan revealed bone progression and 4 new liver lesions. I will be switching from Enhertu (was on Enhertu for a year) to lynparza/ olaparib. Has anyone had success with a parp helping get rid of bone/ liver metastasis for stage 4 breast cancer? Or keeping things stable?
Hello! Unfortunately, my PET scan revealed bone progression and 4 new liver lesions. I will be switching from Enhertu (was on Enhertu for a year) to lynparza/ olaparib. Has anyone had success with a parp helping get rid of bone/ liver metastasis for stage 4 breast cancer? Or keeping things stable?
miconrad
in
SHARE Metastatic Breast Cancer
7 months ago
Zencor & XmAb
My MO discussed a clinical trial for me today if I qualify with the required genetic markers. My most recent PSMA scan showed further progression of metastasis in bone and lymph nodes and my PSA has increased fairly rapidly. Currently taking both Orgovyx & Nubeqa. I'm hoping some of the smart and
My MO discussed a clinical trial for me today if I qualify with the required genetic markers. My most recent PSMA scan showed further progression of metastasis in bone and lymph nodes and my PSA has increased fairly rapidly. Currently taking both Orgovyx & Nubeqa. I'm hoping some of the smart and
AllenMarco
in
Advanced Prostate Cancer
7 months ago
SIBO and antibiotics
l am now feeling so out of my depth. Having been screened and cleared for obvious causes I have seen an NHS Consultant who says I am positive for SIBO. I have tried to work with low fodmap diet previously but without much success. My test with lactose was “equivocal” but a following one with glucose
l am now feeling so out of my depth. Having been screened and cleared for obvious causes I have seen an NHS Consultant who says I am positive for SIBO. I have tried to work with low fodmap diet previously but without much success. My test with lactose was “equivocal” but a following one with glucose
Skyline4
in
IBS Network
4 months ago
is there any hope for me
I haven’t posted much about my journey. I am in the USA. I have never been in true remission. I am braca neg, her2 negative, folate on at 60 % HGS. No mutations in cancer tumor or me. Diagnosed Dec 2019 stage 3c now stage 4 metastasis Here is how much I have fought: Dec2019 full debunking surgery
I haven’t posted much about my journey. I am in the USA. I have never been in true remission. I am braca neg, her2 negative, folate on at 60 % HGS. No mutations in cancer tumor or me. Diagnosed Dec 2019 stage 3c now stage 4 metastasis Here is how much I have fought: Dec2019 full debunking surgery
Summergold2
in
My Ovacome
7 months ago
Alicia Morgans, MD, on PCa in Older Men – Determining frailty or fitness will help guide treatment decisions, MedPageToday, 11/27/2023
Those who dig deep into research methodologies know well the inherent biases that riddle much scientific and medical research. [i](See my postscript reference below) [/i]Clinical trials are not exceptions to these biases and, as drug companies look to produce the best outcomes for their clinical trials
Those who dig deep into research methodologies know well the inherent biases that riddle much scientific and medical research. [i](See my postscript reference below) [/i]Clinical trials are not exceptions to these biases and, as drug companies look to produce the best outcomes for their clinical trials
cujoe
in
Fight Prostate Cancer
7 months ago
Stay positive
Diagnosed march 2021. Debunking surgery 12 rounds chemo. Then onto Zedula . All good until November 2022 more chemo for recurrence then Avastin . My Ca125 stable but just crept up to 36 so need scan and if any signs perhaps more chemo.I have coped really well no real side effects just inally lost
Diagnosed march 2021. Debunking surgery 12 rounds chemo. Then onto Zedula . All good until November 2022 more chemo for recurrence then Avastin . My Ca125 stable but just crept up to 36 so need scan and if any signs perhaps more chemo.I have coped really well no real side effects just inally lost
Guenivere
in
My Ovacome
7 months ago
Why would Active B12 blood test not be recognised by GP when I have lots of symptoms?
I had previously had a blood test for B12 which was apparently normal if a little low. I was told that no treatment was required.I continued to have most of the symptoms of a B12 deficiency so after 4 months and some research I paid for an Active B12 test which showed I was low. I took this to my doctor
I had previously had a blood test for B12 which was apparently normal if a little low. I was told that no treatment was required.I continued to have most of the symptoms of a B12 deficiency so after 4 months and some research I paid for an Active B12 test which showed I was low. I took this to my doctor
GSDLover17
in
Pernicious Anaemia Society
4 months ago
Advice moving forward?
So I recently had blood tests that showed low b12, iron and vit D. Was prescribed tablets for the iron and vit D. And put on a course of B12 loading doses. 6 injections over 2 weeks. it's now been 2 weeks after the last b12 injection and none of my symptoms have improved. When I talked to the gp,
So I recently had blood tests that showed low b12, iron and vit D. Was prescribed tablets for the iron and vit D. And put on a course of B12 loading doses. 6 injections over 2 weeks. it's now been 2 weeks after the last b12 injection and none of my symptoms have improved. When I talked to the gp,
Dan444
in
Pernicious Anaemia Society
5 months ago
fiddle mum- adrenals???
hi- diagnosed 12/21. Currently 2mg pred. Struggled through winter 2 lots antibiotics for chest infections. Finally think chest stuff is resolving. Stopped the 10mg maintenance dose of paroxetine (ssri) 6 weeks ago. Started well but now struggling a bit with anxiety and terrible nervous stomach- leading
hi- diagnosed 12/21. Currently 2mg pred. Struggled through winter 2 lots antibiotics for chest infections. Finally think chest stuff is resolving. Stopped the 10mg maintenance dose of paroxetine (ssri) 6 weeks ago. Started well but now struggling a bit with anxiety and terrible nervous stomach- leading
Fiddlemum
in
PMRGCAuk
5 months ago
B12 deficiency v. Ferritin deficiency
Hi everyone. Some of you may have come across one of my posts this week and may have interacted, but if not, hi 😊 I’ve been going through a lot of the posts on here looking for answers to my query before I post this, but haven’t seen anything that covers it. Is there anybody here that has suffered
Hi everyone. Some of you may have come across one of my posts this week and may have interacted, but if not, hi 😊 I’ve been going through a lot of the posts on here looking for answers to my query before I post this, but haven’t seen anything that covers it. Is there anybody here that has suffered
MLJ2024
in
Pernicious Anaemia Society
5 months ago
Polyps and Abdominal Pain
Background Dec 2023, I started to experience pain when poo’ing, and some significant constipation, that was only relieved with laxatives , once every five days; January 2024 I saw blood on the toilet tissue and started to suffer from abdominal pains. I contacted my GP and after she realised I had
Background Dec 2023, I started to experience pain when poo’ing, and some significant constipation, that was only relieved with laxatives , once every five days; January 2024 I saw blood on the toilet tissue and started to suffer from abdominal pains. I contacted my GP and after she realised I had
Justdoit2015
in
Colon Cancer Connected
5 months ago
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