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Genetic therapy: for solid malignancy hopefully soon
ok, I post them also because they are fellow Italians! But the platform is very promising even if clinical use has been approved only for glioma and glioblastoma at the moment. But there are clinical trials going on for solid tumors, prostate included. https://www.genenta.com/wp-content/uploads/2021
ok, I post them also because they are fellow Italians! But the platform is very promising even if clinical use has been approved only for glioma and glioblastoma at the moment. But there are clinical trials going on for solid tumors, prostate included. https://www.genenta.com/wp-content/uploads/2021
Maxone73
in
Advanced Prostate Cancer
9 months ago
sertraline
Hi all, I’m been on Hrt about 18 months now but my anxiety is still extremely high, as it’s relentles. I’ve tried anti depressants flouxetine and Mirtazipine that haven’t really helped. I’m thinking of trying sertraline next, and was wondering if it has helped anyone with menapausal anxiety please.
Hi all, I’m been on Hrt about 18 months now but my anxiety is still extremely high, as it’s relentles. I’ve tried anti depressants flouxetine and Mirtazipine that haven’t really helped. I’m thinking of trying sertraline next, and was wondering if it has helped anyone with menapausal anxiety please.
BjAli
in
Menopause and Perimenopause Support
3 months ago
Zoladex injection
I began the zoladex injection in January of this year, I then had a laparoscopy in March which diagnosed my endometriosis. I had light bleeding for a couple of weeks after and then it completely stopped. Since then, I've had 2 episodes of heavy bleeding lasting 10 is days. No hormonal treatment has helped
I began the zoladex injection in January of this year, I then had a laparoscopy in March which diagnosed my endometriosis. I had light bleeding for a couple of weeks after and then it completely stopped. Since then, I've had 2 episodes of heavy bleeding lasting 10 is days. No hormonal treatment has helped
CornwallHenleygirl
in
Endometriosis UK
3 months ago
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Could heart pain be related to peri menopause?
Hi everyone. I’ve just recently stopped taking HRT patches as I felt nearly suicidal for two weeks every month. I have been having pains like a stitch in my heart on and off for weeks. Was wondering if any of you have ever experienced anything like this and if it was related to peri menopause
Hi everyone. I’ve just recently stopped taking HRT patches as I felt nearly suicidal for two weeks every month. I have been having pains like a stitch in my heart on and off for weeks. Was wondering if any of you have ever experienced anything like this and if it was related to peri menopause
Ktez
in
Menopause and Perimenopause Support
3 months ago
stitch pains in heart
I’ve recently been told I have Left Ventricle Non Compaction and I also have the dilated cardiomyopathy gene but no symptoms of that yet. My EF is 52 and consultant not too concerned for now. The strange thing is, almost within a day or two or learning this new information, I’ve been having small
I’ve recently been told I have Left Ventricle Non Compaction and I also have the dilated cardiomyopathy gene but no symptoms of that yet. My EF is 52 and consultant not too concerned for now. The strange thing is, almost within a day or two or learning this new information, I’ve been having small
Ktez
in
British Heart Foundation
3 months ago
Ped5i/Tadalafil etc as a benefit to SE of ADT?
Tadalafil , etc is prescribed for ED, BPH and PAH (pulmonary arterial hypertension). It is pretty much agreed upon that Tadalafil increases insulin sensitivity thus improving lean body mass, particularly around the gut, improves Testosterone/estrogen relationship and is good for heart and vascular health
Tadalafil , etc is prescribed for ED, BPH and PAH (pulmonary arterial hypertension). It is pretty much agreed upon that Tadalafil increases insulin sensitivity thus improving lean body mass, particularly around the gut, improves Testosterone/estrogen relationship and is good for heart and vascular health
pj1121
in
Advanced Prostate Cancer
3 months ago
Forgetfulness on ADT
Are there any ways to help with the side effect of forgetfulness / mild cognitive impairment while on ADT? My Dad (stage 4 PC) started on ADT 2 only months ago, but there have been a few moments of mild cognitive impairment since starting - forgetting shopping list, trying to return stuff at the wrong
Are there any ways to help with the side effect of forgetfulness / mild cognitive impairment while on ADT? My Dad (stage 4 PC) started on ADT 2 only months ago, but there have been a few moments of mild cognitive impairment since starting - forgetting shopping list, trying to return stuff at the wrong
LDC2024
in
Advanced Prostate Cancer
3 months ago
Clonazepam
looking for advice. I’ve been taking 1mg Clonazepam to help sleep but I e read quite a few horror stories about it so it’s making me nervous about taking it. I’ve not slept for six months and my tinnitus has become rea tube to virtually every sound you can think of. I believe it become my nervous system
looking for advice. I’ve been taking 1mg Clonazepam to help sleep but I e read quite a few horror stories about it so it’s making me nervous about taking it. I’ve not slept for six months and my tinnitus has become rea tube to virtually every sound you can think of. I believe it become my nervous system
Lakeshiker
in
Tinnitus UK
3 months ago
Well, three years in…..
Since initial DX of Gleason 4+4….. at that time was stage 4 high volume metastic disease. PSA can move up and down quickly. went up 10 points in a week went down 33 points in a month, without treatment. i went from NED of disease to PSA of 28.5 in six months. it’s a spunky little bastard. sorta like
Since initial DX of Gleason 4+4….. at that time was stage 4 high volume metastic disease. PSA can move up and down quickly. went up 10 points in a week went down 33 points in a month, without treatment. i went from NED of disease to PSA of 28.5 in six months. it’s a spunky little bastard. sorta like
FulThrotl
in
Advanced Prostate Cancer
3 months ago
Vitamins with ADT?
Hi Tall_Allen, You do not recommend vitamins when on ADT? I am on daily Casodex, has been for several years, and I am taking - Multivitamins, C-, D-, K- vitamins and magnesium daily. Should I stop this? Can you elaborate a bit on why you do not recommend taking vitamins? Thanks in advance!
Hi Tall_Allen, You do not recommend vitamins when on ADT? I am on daily Casodex, has been for several years, and I am taking - Multivitamins, C-, D-, K- vitamins and magnesium daily. Should I stop this? Can you elaborate a bit on why you do not recommend taking vitamins? Thanks in advance!
PCPatient
in
Advanced Prostate Cancer
3 months ago
Disgusted with Healthcare
I had to request my PCP to do a PSA as it wasn't standard practice. I had to call the urologist, who I originally saw, after I joined this board and knew I should be starting ADT, even though they hadn't two months after my scans showed Stage IV. I saw the surgeon even though it was Stage IV and wasn't
I had to request my PCP to do a PSA as it wasn't standard practice. I had to call the urologist, who I originally saw, after I joined this board and knew I should be starting ADT, even though they hadn't two months after my scans showed Stage IV. I saw the surgeon even though it was Stage IV and wasn't
Vangogh1961
in
Advanced Prostate Cancer
3 months ago
Low Testosterone Linked With Mortality Risk in Aging Men - by Jeff Minerd , Contributing Writer, MedPage Today May 13, 2024
No way to know if this is applicable to those on ADT, but it would seem to be relevant for consideration. The highlighted portion is a useful guide on male sex hormone targets for those testing them. These results might also add support for Morgentaler's [i]"Saturation Model"[/i] for testosterone. Full
No way to know if this is applicable to those on ADT, but it would seem to be relevant for consideration. The highlighted portion is a useful guide on male sex hormone targets for those testing them. These results might also add support for Morgentaler's [i]"Saturation Model"[/i] for testosterone. Full
cujoe
in
Fight Prostate Cancer
3 months ago
Malabsorption of drugs?
I am still awaiting a diagnosis of PA, but do suspect I do have it. My stomach pH level was recently 8.1, so very low stomach acid, which is why I am not absorbing/processing B12, iron and folate. I also did a test which showed I have very low diamine oxidase in my gut so have histamine intolerance.
I am still awaiting a diagnosis of PA, but do suspect I do have it. My stomach pH level was recently 8.1, so very low stomach acid, which is why I am not absorbing/processing B12, iron and folate. I also did a test which showed I have very low diamine oxidase in my gut so have histamine intolerance.
Chickens44
in
Pernicious Anaemia Society
3 months ago
Compression fracture or something worse?
Hello! My dad has been battling stage four prostate cancer for nearly nine years. He's done remarkably well, all things considered. He's had chemo, hormone therapy, immunotherapy, radiation, and second line hormone therapy. Along the way he has had heart issues and also CNS lymphoma (brain cancer).
Hello! My dad has been battling stage four prostate cancer for nearly nine years. He's done remarkably well, all things considered. He's had chemo, hormone therapy, immunotherapy, radiation, and second line hormone therapy. Along the way he has had heart issues and also CNS lymphoma (brain cancer).
Lynsi13
in
Advanced Prostate Cancer
3 months ago
Penis after metastatic prostrate cancer and hormonal treatment
HelloI was diagnosed in September 2022. Was immediately put on ADT hormonal treatment. Had radiation to the prostrate and radiation to the spine where it spread. My issue is penis shrinkage. Because of the hormonal treatment I have issues with getting with errections. Also was told by many fellow journeymen
HelloI was diagnosed in September 2022. Was immediately put on ADT hormonal treatment. Had radiation to the prostrate and radiation to the spine where it spread. My issue is penis shrinkage. Because of the hormonal treatment I have issues with getting with errections. Also was told by many fellow journeymen
RWRB
in
Men's Health Forum (Penis Health)
3 months ago
T3 only and feeling a bit desperate
I have been taking T3 only for a handful of years now and for a couple of them on a LCHF diet I was happy enough. I lost weight, and felt good. In October 2020 I restarted HRT (I still had/have) hot flushes, but within 2 months I had started to gain weight and on balance I thought that I would rather
I have been taking T3 only for a handful of years now and for a couple of them on a LCHF diet I was happy enough. I lost weight, and felt good. In October 2020 I restarted HRT (I still had/have) hot flushes, but within 2 months I had started to gain weight and on balance I thought that I would rather
Icicles
in
Thyroid UK
3 months ago
PSA is back
I was 51 yr old diagnosed with Prostate cancer state 1 with a PSA 4.7. Gleasons mixed of 3+3's and 3+4's.I had robotic prostatectomy. Psa was undetectable until January 2023 and slowly creeped back up to .19 now in April 2024 . Just started Hormonal Therapy with radiation scheduled for August.
I was 51 yr old diagnosed with Prostate cancer state 1 with a PSA 4.7. Gleasons mixed of 3+3's and 3+4's.I had robotic prostatectomy. Psa was undetectable until January 2023 and slowly creeped back up to .19 now in April 2024 . Just started Hormonal Therapy with radiation scheduled for August.
LBbeachbum
in
Prostate Cancer Network
3 months ago
Tiberlone and zoledex
I started hrt tiberlone 10 days ago same time as my 2nd injection and after i take the hrt with 2 hours ive got major flare ups that last hours then i feel great.Do i stick it out as the pain is awful, ended up in a&e and after tests told its flare ups Really getting me down as my surgery is 12-18 months
I started hrt tiberlone 10 days ago same time as my 2nd injection and after i take the hrt with 2 hours ive got major flare ups that last hours then i feel great.Do i stick it out as the pain is awful, ended up in a&e and after tests told its flare ups Really getting me down as my surgery is 12-18 months
Chartolfrey
in
Endometriosis UK
3 months ago
Help understanding recent blood test results.. next steps?
Hello, I am looking for some help interpreting my recent thyroid bloods. TSH 3.04 (range 0.40-2.50 high FT4 9.01 range 7.86-14.41 FT3 3.4 range 3.8-6.0 low RT3 0.30 range 0.14-0.54 TT4 74.10 range 78.38-157.40 low FT4:FT3 ratio 2.7 Anti TG <0.9 Anti TPO <1 How do I interpret these results
Hello, I am looking for some help interpreting my recent thyroid bloods. TSH 3.04 (range 0.40-2.50 high FT4 9.01 range 7.86-14.41 FT3 3.4 range 3.8-6.0 low RT3 0.30 range 0.14-0.54 TT4 74.10 range 78.38-157.40 low FT4:FT3 ratio 2.7 Anti TG <0.9 Anti TPO <1 How do I interpret these results
PaleoGirl
in
Thyroid UK
3 months ago
Stopping Orgovyx after six months
My brother has PCa as well. We keep it in the family... He had a PT ten years ago but his PSA rose so he got salvage radiation and went on Orgovyx. His MO said he would be on it for 18 months, as is SOC. He didn't like his MO so he switched to a GU MO. That MO said the research showed six months of ADT
My brother has PCa as well. We keep it in the family... He had a PT ten years ago but his PSA rose so he got salvage radiation and went on Orgovyx. His MO said he would be on it for 18 months, as is SOC. He didn't like his MO so he switched to a GU MO. That MO said the research showed six months of ADT
gsun
in
Advanced Prostate Cancer
3 months ago
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