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Understanding the Threat of Micrometastases (also known as Minimal Residual Disease) in Prostate Cancer or Don't sweat the small stuff
Greetings followers of FPC; It is time to set things straight in regards to the oligometastatic state in prostate caner. Posters will tell you that it does not exist because of micrometastases. So let's take a look at micrometastases first. The dreaded micrometastases.....the ultimate death sentence
Greetings followers of FPC; It is time to set things straight in regards to the oligometastatic state in prostate caner. Posters will tell you that it does not exist because of micrometastases. So let's take a look at micrometastases first. The dreaded micrometastases.....the ultimate death sentence
NPfisherman
in
Fight Prostate Cancer
3 months ago
ADT failure
We saw my Dad's MO on 5/23. Over the course of 4 weeks my dad's PSA moved from 1.46 to 2.14, He said we need to be on Zytiga for three months before we can deem it a failure, but just like Xtandi, it appears my dad had limited help with it. We have talked about the next steps, chemo and pluvicto. My
We saw my Dad's MO on 5/23. Over the course of 4 weeks my dad's PSA moved from 1.46 to 2.14, He said we need to be on Zytiga for three months before we can deem it a failure, but just like Xtandi, it appears my dad had limited help with it. We have talked about the next steps, chemo and pluvicto. My
lgutman
in
Advanced Prostate Cancer
3 months ago
Need surgery
Hi I'm not new here but I thought I'd take a shot in the dark and explain the predicament that I am in. I have a prolapsed stoma which is 4 inches long and 55mm in diameter I've also herniated my bowel with it being 10cm in length. I also have 1 metre of small bowel left so not really much at all when
Hi I'm not new here but I thought I'd take a shot in the dark and explain the predicament that I am in. I have a prolapsed stoma which is 4 inches long and 55mm in diameter I've also herniated my bowel with it being 10cm in length. I also have 1 metre of small bowel left so not really much at all when
Joeyskin
in
IBS Network
3 months ago
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Side effect of Lupron
We have a quesiton about swelling foot and ankle after Lupron injection and wonder if anyone has had a similar experience. My husband was just diagnosed with PC back in April, and he is on ADT while waiting for his CK treatment this month. After three-weeks of Lupron injection, he now has a swollen
We have a quesiton about swelling foot and ankle after Lupron injection and wonder if anyone has had a similar experience. My husband was just diagnosed with PC back in April, and he is on ADT while waiting for his CK treatment this month. After three-weeks of Lupron injection, he now has a swollen
kiyo
in
Prostate Cancer Network
3 months ago
Hypogonadism, heat flushing, and testosterone replacement
Hi all, It is almost a year since I had my external beam radiation for Gleason 7 (3+4) PCa (see my profile). So far so good: 4 PSA tests were reassuringly low. I am now almost 82 and I am hoping to deal with my strange heat-flushing problem, which I have had for several years. It predates my cancer
Hi all, It is almost a year since I had my external beam radiation for Gleason 7 (3+4) PCa (see my profile). So far so good: 4 PSA tests were reassuringly low. I am now almost 82 and I am hoping to deal with my strange heat-flushing problem, which I have had for several years. It predates my cancer
Smarks42
in
Prostate Cancer Network
3 months ago
Ultrahypofractional RT and ADT for Int. Risk PC
I am a 60 year old recently diagnosed PC with a PSA of 11.3 and ultra sound biopsy grade cT1c Gleason 3+4 = 7 Right basal and 3+3 on Right medial only 2 of 12 cores contain cancer. MRI showed PI Rads 5 lesion in right basal peripheral zone and extension into right seminal vesicle. Chose to go with
I am a 60 year old recently diagnosed PC with a PSA of 11.3 and ultra sound biopsy grade cT1c Gleason 3+4 = 7 Right basal and 3+3 on Right medial only 2 of 12 cores contain cancer. MRI showed PI Rads 5 lesion in right basal peripheral zone and extension into right seminal vesicle. Chose to go with
Hidden
in
Prostate Cancer Network
3 months ago
breathless when hypothyroid?
I am currently “dysthyroid” as my gp puts it. Briefly - diagnosed with hypothyroid disease in 2016 (all antibodies negative). Since starting transdermal hrt in Jan my thyroid levels hv plummeted (result posted recently but roughly T4 7.2 (11-22) and T3 2 (3.2-6.8). These results are from when I was taking
I am currently “dysthyroid” as my gp puts it. Briefly - diagnosed with hypothyroid disease in 2016 (all antibodies negative). Since starting transdermal hrt in Jan my thyroid levels hv plummeted (result posted recently but roughly T4 7.2 (11-22) and T3 2 (3.2-6.8). These results are from when I was taking
Popscicle
in
Thyroid UK
3 months ago
Hot Flashes
Centrum is advertising a number of products that reduce hot flashes in post menopausal women. Are any of these effective for those of us on ADT ?
Centrum is advertising a number of products that reduce hot flashes in post menopausal women. Are any of these effective for those of us on ADT ?
alperk
in
Advanced Prostate Cancer
3 months ago
Binding globulins...
Anyone got a good handle on these, please? The reason I ask is that I have had 3 months of increasingly debilitating fatigue. I take T3 only and was on 100mcg, which took me 70% through the range, I have also tried 125mcg which takes me well over the top, but still tiredddddd. I have tested cortisol
Anyone got a good handle on these, please? The reason I ask is that I have had 3 months of increasingly debilitating fatigue. I take T3 only and was on 100mcg, which took me 70% through the range, I have also tried 125mcg which takes me well over the top, but still tiredddddd. I have tested cortisol
AKatieD
in
Thyroid UK
3 months ago
How is the second generation ADT like xtandi , zytiga etc decided ?
What determines which second line ADT will be given to whom ? I see there is zytiga , xtandi , nubeqa and others. Is it just left to the MO to decide ?
What determines which second line ADT will be given to whom ? I see there is zytiga , xtandi , nubeqa and others. Is it just left to the MO to decide ?
Tinkudi
in
Advanced Prostate Cancer
3 months ago
Does Decapeptyl ever just stop working?
Hello. I have an appointment in a couple of months with my gynae to review my treatment. I've been on Decapeptyl for two and a half years now, with low dose HRT to keep hot flushes etc at bay. I had a lap about 18 months ago. I do have occasional pain but nowhere near as bad as it was pre-lap and pre-injection
Hello. I have an appointment in a couple of months with my gynae to review my treatment. I've been on Decapeptyl for two and a half years now, with low dose HRT to keep hot flushes etc at bay. I had a lap about 18 months ago. I do have occasional pain but nowhere near as bad as it was pre-lap and pre-injection
atealdeer
in
Endometriosis UK
3 months ago
Pelvic pain back 3 months after Hysterectomy
I have had significant pelvic pain with bowel and bladder issues for 2.5 years. It was hard to get a diagnosis. I was told at first it was a bowel issue, then Endometriosis/Adenomyosis and was eventually diagnosed with 4 fibroids, 1 being 7cm. A year ago, I was put on Prostap and add back hrt. The Prostap
I have had significant pelvic pain with bowel and bladder issues for 2.5 years. It was hard to get a diagnosis. I was told at first it was a bowel issue, then Endometriosis/Adenomyosis and was eventually diagnosed with 4 fibroids, 1 being 7cm. A year ago, I was put on Prostap and add back hrt. The Prostap
Mindfullness4791
in
Endometriosis UK
3 months ago
Original pelvic pain back 3 months after hysterectomy
To cut a very long story short. I have had significant pelvic pain with bowel and bladder issues for 2.5 years. It was difficult to get a diagnosis. I was told at first it was a bowel issue, then Endometriosis/Adenomyosis and was eventually diagnosed with 4 fibroids, 1 being 7cm. A year ago, I was put
To cut a very long story short. I have had significant pelvic pain with bowel and bladder issues for 2.5 years. It was difficult to get a diagnosis. I was told at first it was a bowel issue, then Endometriosis/Adenomyosis and was eventually diagnosed with 4 fibroids, 1 being 7cm. A year ago, I was put
Mindfullness4791
in
Pelvic Pain Support Network
3 months ago
How do I gradually run faster, what’s best?
I need to go to go out & do Wk 8 Run 2 this morning & prevaricating (but will do it) …. I’m an exceptionally slow runner and run 1 on Wednesday felt rubbish, so was good to read about Toxic 10 & Tomato Ten in someone else’s post as I do have these! (And in swimming too!) I want to run gradually faster
I need to go to go out & do Wk 8 Run 2 this morning & prevaricating (but will do it) …. I’m an exceptionally slow runner and run 1 on Wednesday felt rubbish, so was good to read about Toxic 10 & Tomato Ten in someone else’s post as I do have these! (And in swimming too!) I want to run gradually faster
Snippit
Graduate
in
Couch to 5K
3 months ago
Using Red Clover, Sage and Ashwagandha for the menopause, and it's safety with hypothyroidism?
Hiya. I am currently in the menopause with early onset osteoporosis, and have autoimmune related hypothyroidism. I am looking into various ways to manage this, conventional HRT being the least desirable. I much prefer natural ways to manage my health wherever possible, and I've found various herbal supplements
Hiya. I am currently in the menopause with early onset osteoporosis, and have autoimmune related hypothyroidism. I am looking into various ways to manage this, conventional HRT being the least desirable. I much prefer natural ways to manage my health wherever possible, and I've found various herbal supplements
MindfulMoments
in
Thyroid UK
3 months ago
Pick and mitch advice.
My hormones have been leveled out now for 1.5 years since I got my depo provera sorted. But my smacking head ache that comes on when the progesterone drops came back for one day before my last injection and disappeared in hours after the injection was done.My new shifts at my job mean I'm going to be
My hormones have been leveled out now for 1.5 years since I got my depo provera sorted. But my smacking head ache that comes on when the progesterone drops came back for one day before my last injection and disappeared in hours after the injection was done.My new shifts at my job mean I'm going to be
SavageGold
in
Endometriosis UK
3 months ago
Comparative Effectiveness of Levothyroxine, Desiccated Thyroid Extract, and Levothyroxine+Liothyronine in Hypothyroidism.....a study
Comparative Effectiveness of Levothyroxine, Desiccated Thyroid Extract, and Levothyroxine+Liothyronine in Hypothyroidism
https://academic.oup.com/jcem/article/106/11/e4400/6311304 [u]
The rationale behind thyroid hormone replacement therapy is to administer thyroid hormone in a way that restores
Comparative Effectiveness of Levothyroxine, Desiccated Thyroid Extract, and Levothyroxine+Liothyronine in Hypothyroidism
https://academic.oup.com/jcem/article/106/11/e4400/6311304 [u]
The rationale behind thyroid hormone replacement therapy is to administer thyroid hormone in a way that restores
DippyDame
in
Thyroid UK
3 months ago
Early breast cancer
I've just been diagnosed with early breast cancer. I've had mammogram, biopsy and mri. The lump is 3cm. I am awaiting a tests on my lymph nodes. Then have been told lumpectomy, radiotherapy and /or chemotherapy. It's oestrogen and progesterone driven. I am on hrt, I'm perimenopausal. I also had a heart
I've just been diagnosed with early breast cancer. I've had mammogram, biopsy and mri. The lump is 3cm. I am awaiting a tests on my lymph nodes. Then have been told lumpectomy, radiotherapy and /or chemotherapy. It's oestrogen and progesterone driven. I am on hrt, I'm perimenopausal. I also had a heart
Duvetdays15
in
My Breast Cancer Community
3 months ago
apalutamide vs. abiraterone
My husband has been recommended ADT + abiraterone + prednisone for two years. My friend who is an oncologist suggested apalutamide instead as it doesn't need to be supplements with prednisone and has less side effects. Wanted your opinion.
My husband has been recommended ADT + abiraterone + prednisone for two years. My friend who is an oncologist suggested apalutamide instead as it doesn't need to be supplements with prednisone and has less side effects. Wanted your opinion.
SherryKahn
in
Advanced Prostate Cancer
3 months ago
SUV-Max
Hello , Ive been on Eligard , Zytiga , predizone 26 months . Im oligo with 1 tumor in pelvic lymph node that was radiated , then 25 fractions across the pelvic region . The tumor they radiated was at SUV-MAX 24 . All labs are good , not much of side effects . I thought about stopping the meds after
Hello , Ive been on Eligard , Zytiga , predizone 26 months . Im oligo with 1 tumor in pelvic lymph node that was radiated , then 25 fractions across the pelvic region . The tumor they radiated was at SUV-MAX 24 . All labs are good , not much of side effects . I thought about stopping the meds after
reconjj
in
Advanced Prostate Cancer
3 months ago
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