Experiences with

Pernicious anaemia

https://www.justgiving.com/page/rebecca-garner-pernicious-anaemia-bath-half?utm_medium=fundraising&utm_content=page%2Frebecca-garner-pernicious-anaemia-bath-half&utm_source=copyLink&utm_campaign=pfp-share

The presence of anti intrinsic factor antibodies together with a low vitamin B12 level is diagnostic of pernicious anaemia Does this make sense to anyone and could you please explain it to me as they said I had pernicious anaemia but didn't fully explain the results. Thanks in advance

This Pernicious Anaemia Society blog was highlighted by   Sleepybunny - and almost immediately stolen and posted here by me. This was her blog: [i]This one written by PAS (Pernicious Anaemia Society) chair Katrina Burchell is definitely worth reading. I'm sure many of us can relate to these issues.

She has booked me for another gastroscopy for her to do biopsies to confirm whether I have pernicious anaemia or not. I am now wondering whether I do have true Pernicious Anaemia. I self inject twice a week and sometimes still have pins and needles and weakness, however has much improved.

We know that certain gastric operations cause Pernicious Anaemia and therefore lifelong b12 injections are required . But what I’ve never seen mentioned is the possibility of radiotherapy cancer treatment in the region of the stomach that contains the parietal cells , causing Pernicious Anaemia .

We are the only charity worldwide funding such research into Pernicious Anaemia. https://pernicious-anaemia-society.org/member/

So as well as Pernicious Anaemia it seems I may have acquired aplastic anaemia according to my bone marrow results. Does anyone else have this?

., but I know they don’t always accurately reflect the underlying condition.It also means my pernicious anaemia could be due to long term use of PPIs rather than autoimmune gastritis. (By the way stopped PPIs in December last year) .

I am at the start of this minefield of Pernicious Anaemia, after reading the struggles of PA stories and this site, I feel fortunate that I have not suffered as many members have.

And Pernicious Anaemia is not my focus.)

On the Pernicious Anaemia Society forum, there is a new thread re the newly released NICE guidelines for Pernicious Anaemia/B12 Deficiency Diagnosis and Treatment in Over 16s [i]New NICE guidelines [/i] https://healthunlocked.com/pasoc/posts/150619728/new-nice-guidelines Within that thread,

The auto-antibody is found at high frequency in association with autoimmune gastritis and a proportion of these patients will progress to develop pernicious anaemia. Gastric parietal cell antibodies are present in over 90% of patients with pernicious anaemia (Highly sensitive, but not specific).

Psychology in Wellness – Pernicious Anaemia https://pernicious-anaemia-society.org/blog/hope-and-psychology-in-wellness-pernicious-anaemia/

I was diagnosed back in Feb this year after my Intrinsic Factor blood test came back positive and I was diagnosed with Pernicious anaemia. I went to the drs with symptoms of exhaustion, pins and needles, heart palpitations and nausea as well as brain fog.

What does this mean for those with Anaemia whether formally diagnosed or not? What does it mean with those struggling to get sufficiently frequent treatment for their B12 deficiency?

, my dr didn’t even tell me it was pernicious anaemia just that I had autoimmune issues after testing positive for parietal cell antibody , intrinsic factor was ok apparently, it was the gastroenterologist who confirmed I had pernicious anaemia 6 months after the test !

I am wondering if anyone with PMR and/or GCA (both of which I've got/had) has also been diagnosed with anaemia. I notice that Pernicious Anaemia is another autoimmune condition. My GP called me in as my monthly blood tests had suggested I might have anaemia.

This was given in the context of seeking a diagnosis of my B12 deficiency which was said to be linked with the above, Pernicious Anaemia, antibodies attacking thyroid and gastric parietal cells. I have been on levothyroxin for 15yrs. He based this partly on my raised Anti-Tg (67IU/ml).

This was given in the context of seeking a diagnosis of my B12 deficiency which was said to be linked with the above, Pernicious Anaemia, antibodies attacking thyroid and gastric parietal cells. I have been on levothyroxin for 15yrs. He based this partly on my raised Anti-Tg (67IU/ml).

(I have low B12 and low vit D and am awaiting results for ceoliac and pernicious anaemia so I'm wondering if it could be related to absorption?) Thanks