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Wack a Mole and itching
Does anyone else who is on dialysis feel like they are the mole in the game called Wack-a-mole. It is the game where the mole pops out of a hole and you are supposed to bop him on the head and then he disappears only to pop up in another hole. That's dialysis to me. I am doing HHD. I am having terrible
Does anyone else who is on dialysis feel like they are the mole in the game called Wack-a-mole. It is the game where the mole pops out of a hole and you are supposed to bop him on the head and then he disappears only to pop up in another hole. That's dialysis to me. I am doing HHD. I am having terrible
Bassetmommer
in
Kidney Dialysis
18 days ago
Interesting Alzheimer's paper provides alternative explanation regarding the mode of action of monoclonal antibodies such as lecanemab.
"For decades, the prevailing theory in the field has stated that a protein made up of 42 amino acids called amyloid-beta 42 (Aβ42) hardens into clumps called amyloid plaques, and those plaques damage the brain, causing Alzheimer's disease." "Led by UC's Alberto Espay, MD, the team have hypothesized
"For decades, the prevailing theory in the field has stated that a protein made up of 42 amino acids called amyloid-beta 42 (Aβ42) hardens into clumps called amyloid plaques, and those plaques damage the brain, causing Alzheimer's disease." "Led by UC's Alberto Espay, MD, the team have hypothesized
jeffreyn
in
Cure Parkinson's
18 days ago
PA and the Dentist
I have found someone who understand PA ! My new dentist. I have had PA since 2015 and this is only the second person. The other was a physiotherapist whose sister had it. I broke a tooth and had to see a different partner in the practice and told her I had PA and she said " oh dear, that is difficult
I have found someone who understand PA ! My new dentist. I have had PA since 2015 and this is only the second person. The other was a physiotherapist whose sister had it. I broke a tooth and had to see a different partner in the practice and told her I had PA and she said " oh dear, that is difficult
purpleabc
in
Pernicious Anaemia Society
18 days ago
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PSA rising
I had spot radiation in June for olio metastatic (2 spots), PSA was .036. In Aug PSA went down to .028. Now it’s .031. Does this mean the radiation of the 2 spots did not work? How long should I wait before ADT?
I had spot radiation in June for olio metastatic (2 spots), PSA was .036. In Aug PSA went down to .028. Now it’s .031. Does this mean the radiation of the 2 spots did not work? How long should I wait before ADT?
Howard53545
in
Advanced Prostate Cancer
18 days ago
Fibroscan and Biopsy Showing Wildly Different Results
Really could use some help! So I've had yet another Fibroscan with the results showing the same as before, basically Level 0-1 fibrosis. Can someone please help reconcile those results with my recent liver biopsy showing Stage 3-4 advanced liver disease transitioning to cirrhosis? My hepatologist theorizes
Really could use some help! So I've had yet another Fibroscan with the results showing the same as before, basically Level 0-1 fibrosis. Can someone please help reconcile those results with my recent liver biopsy showing Stage 3-4 advanced liver disease transitioning to cirrhosis? My hepatologist theorizes
lakewoodliver
in
British Liver Trust
19 days ago
GPT PD Coach - Enhancing Neuroplasticity in Parkinson's Disease
GPT PD Coach - Enhancing Neuroplasticity in Parkinson's Disease (Developed by Manu Férriz in a totally disinterested way) Current status: testing the first prototype without metrics or protocols. Whoever wants to test it can report its progress through the following email mferriz@gmail.com. I will be
GPT PD Coach - Enhancing Neuroplasticity in Parkinson's Disease (Developed by Manu Férriz in a totally disinterested way) Current status: testing the first prototype without metrics or protocols. Whoever wants to test it can report its progress through the following email mferriz@gmail.com. I will be
ManuCalma
in
Cure Parkinson's
19 days ago
SECuRE trial (Cu 67) advances: No dose limiting toxicities and strong preliminary efficacy data
It keeps being promising, but keep an eye also on Pb 212, which on paper should be even better for prostate cancer. After 2 cycles: "Early preliminary efficacy assessment shows a reduction in PSA levels following treatment in both participants who have completed the DLT period. In the weeks following
It keeps being promising, but keep an eye also on Pb 212, which on paper should be even better for prostate cancer. After 2 cycles: "Early preliminary efficacy assessment shows a reduction in PSA levels following treatment in both participants who have completed the DLT period. In the weeks following
Maxone73
in
Advanced Prostate Cancer
19 days ago
C15- could it be helpful?
I found this interesting https://youtu.be/cnTHgRJi0mM?si=ApWx2Y0rI7PPBsMY From chatgpt Fats and oils are composed of fatty acids, which can vary in the length of their carbon chains. The length of the carbon chain influences the properties, metabolism, and health effects of the fat. Fatty acids are
I found this interesting https://youtu.be/cnTHgRJi0mM?si=ApWx2Y0rI7PPBsMY From chatgpt Fats and oils are composed of fatty acids, which can vary in the length of their carbon chains. The length of the carbon chain influences the properties, metabolism, and health effects of the fat. Fatty acids are
LAJ12345
in
Cure Parkinson's
20 days ago
Sad & Scared
My husband began Docetaxel in July. At the time he PSA was 47. After treatments began his PSA progression was 47—32—18 We were so encouraged. After his 3rd Infusion today, his PSA went up to 19.2 I know it is only slight but yet not going downward. Does this mean he has potentially reached nadir
My husband began Docetaxel in July. At the time he PSA was 47. After treatments began his PSA progression was 47—32—18 We were so encouraged. After his 3rd Infusion today, his PSA went up to 19.2 I know it is only slight but yet not going downward. Does this mean he has potentially reached nadir
JolleySprings
in
Advanced Prostate Cancer
20 days ago
Hemin may be useful as prodrug for prostate cancer. It strongly induced caspase-3 activation, PARP degradation, and apoptosis in PC-3 cells
Only an invitro study but Hemin is already used to treat acute porphyria. “Given that hemin has been safely administered as a daily infusion at doses ranging from 1 to 4 mg/kg for 3 to 14 days in the treatment of porphyria [32], it holds significant promise for drug development.” Anticancer Effect of
Only an invitro study but Hemin is already used to treat acute porphyria. “Given that hemin has been safely administered as a daily infusion at doses ranging from 1 to 4 mg/kg for 3 to 14 days in the treatment of porphyria [32], it holds significant promise for drug development.” Anticancer Effect of
Graham49
in
Fight Prostate Cancer
20 days ago
Another one of many
PSA tested in June 2023 due to a friend who had an issue and encouraged testing. PSA at 43, second test at 40. Biopsy ordered which came in at 4 +5. Moved treatment to UCLA where a PET scan was ordered. Metastatic cancer in 8 locations with 1 lymph node effected, remaining locations spread through different
PSA tested in June 2023 due to a friend who had an issue and encouraged testing. PSA at 43, second test at 40. Biopsy ordered which came in at 4 +5. Moved treatment to UCLA where a PET scan was ordered. Metastatic cancer in 8 locations with 1 lymph node effected, remaining locations spread through different
Wave-Runner
in
Advanced Prostate Cancer
20 days ago
Post-Treatment Recovery and PSA Levels: Seeking Guidance After SBRT and ADT
68-Year-Old with Localized Gleason 9 (4+5)
Diagnosis:
September 2022 Treatment Plan: 18 months of Lupron (started October 2022) and five sessions of SBRT, completed in December 2022. Current Status: Took my last Lupron shot in January 2024. Just had a blood test yesterday (PSA and testosterone
68-Year-Old with Localized Gleason 9 (4+5)
Diagnosis:
September 2022 Treatment Plan: 18 months of Lupron (started October 2022) and five sessions of SBRT, completed in December 2022. Current Status: Took my last Lupron shot in January 2024. Just had a blood test yesterday (PSA and testosterone
SierraSix
in
Advanced Prostate Cancer
20 days ago
When did you feel some hope you might pull out of this and not die next week?
New diagnosis. What i thought was back pain just turned out to be Advanced Metastatic PROSTATE Cancer on a CT Scan with contrast and PSA of 56. I've been blessed with excellent health til now. This is all scary NEW to me and my wife, we are in shock. Oncologist/Urologist ordered a ultrasound guided
New diagnosis. What i thought was back pain just turned out to be Advanced Metastatic PROSTATE Cancer on a CT Scan with contrast and PSA of 56. I've been blessed with excellent health til now. This is all scary NEW to me and my wife, we are in shock. Oncologist/Urologist ordered a ultrasound guided
ELOfan
in
Advanced Prostate Cancer
20 days ago
Good news on memory following B12 treatment
Hi, some of the regular posters may remember me posting in absolute despair last autumn about my husband’s cognitive issues and extreme memory loss. I’m now posting an update in case it helps anyone else in his position. In summary he had experienced symptoms over a couple of decades since he was twenty
Hi, some of the regular posters may remember me posting in absolute despair last autumn about my husband’s cognitive issues and extreme memory loss. I’m now posting an update in case it helps anyone else in his position. In summary he had experienced symptoms over a couple of decades since he was twenty
Zmalp
in
Pernicious Anaemia Society
6 months ago
Post Cerebral Abscess recovery
Hi I am looking for some guidance, help or support suggestions. My father in law last May collapsed with stroke like symptoms with weakness in his right side of body in arm and leg, slurred speech and confusion. Whilst in our local hospital, after doing a CT scan, the initially changed their diagnosis
Hi I am looking for some guidance, help or support suggestions. My father in law last May collapsed with stroke like symptoms with weakness in his right side of body in arm and leg, slurred speech and confusion. Whilst in our local hospital, after doing a CT scan, the initially changed their diagnosis
Tomos0608
in
Headway
21 days ago
If PSA rises when one is on ADT does it always mean resistance or can it be only a particular met growing ?
I see some posts here mention that some people had a psa rise and then got some met radiated and psa went down again. So one is on hormone therapy and psa rises , it does not necessarily mean one is getting castrate resistant ? Just trying to educate myself 😊
I see some posts here mention that some people had a psa rise and then got some met radiated and psa went down again. So one is on hormone therapy and psa rises , it does not necessarily mean one is getting castrate resistant ? Just trying to educate myself 😊
Tinkudi
in
Advanced Prostate Cancer
21 days ago
Advice required please
Hi, hoping someone here can help/advise. I was diagnosed with PBC 18 months ago and thankfully I have responded to Urso Acid. From the start I was on Ursofalk but this month the prescription I have just collected is Cholurso. Are they all the same and it’s just a generic name from a manufacturer?
Hi, hoping someone here can help/advise. I was diagnosed with PBC 18 months ago and thankfully I have responded to Urso Acid. From the start I was on Ursofalk but this month the prescription I have just collected is Cholurso. Are they all the same and it’s just a generic name from a manufacturer?
Cascade35
in
PBC Foundation
21 days ago
Preparing for an ablation for atrial fibrillation
The procedure can be performed either under general anaesthetic, or under sedation and the time it takes may vary depending upon several factors including; the type of AF you have, the technique used, general health and how long the AF has been present, and other any other underlying health conditions
The procedure can be performed either under general anaesthetic, or under sedation and the time it takes may vary depending upon several factors including; the type of AF you have, the technique used, general health and how long the AF has been present, and other any other underlying health conditions
SamAdmin
Administrator
in
Atrial Fibrillation Support
22 days ago
PSA rise, when would one be concerned???
Stage 4 at diagnosis 2y ago with Gleason 9spread in bone in pelvice and possibly elsewhere. Had chemo and radiotherapy (to prostate) Lupron injections 3 monthly PSA results May23 0.08 Dec23 0.25 Feb24 0.44 June24 0.58 Sep24 1.1 I know they are not massive PSA values, but it's an upward trajectory. What
Stage 4 at diagnosis 2y ago with Gleason 9spread in bone in pelvice and possibly elsewhere. Had chemo and radiotherapy (to prostate) Lupron injections 3 monthly PSA results May23 0.08 Dec23 0.25 Feb24 0.44 June24 0.58 Sep24 1.1 I know they are not massive PSA values, but it's an upward trajectory. What
Mrtroxely
in
Advanced Prostate Cancer
23 days ago
Good News on NAFLD and Rezdiffra
In March 2024, my wife had two Fibroscans, 14.2 and 14.7 with CAP in high 300's. She had a biopsy in July confirming severe steatosis and F3 fibrosis verging on F4. University of Utah liver clinic recommended a new drug called Rezdiffra. It's pricy like any new drug. But, there are foundations
In March 2024, my wife had two Fibroscans, 14.2 and 14.7 with CAP in high 300's. She had a biopsy in July confirming severe steatosis and F3 fibrosis verging on F4. University of Utah liver clinic recommended a new drug called Rezdiffra. It's pricy like any new drug. But, there are foundations
TheTimer
in
British Liver Trust
23 days ago
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