Experiences with

Opioid substitution treatment

I was unable to continue on Alendronic tablets so was switched to annual infusions. The regime was one infusion per year over three years and my last one was on 20/8/21. I was unaware that this treatment comprises certain dental treatments, I know of extractions but uncertain if it applies to anything

Coming up to my 2 year anniversary on prednisolone and I seem worse than ever. On 6 mg daily atm. A lot has gone on in the last few months, a 3 week trip to Mexico in November and woke up on the day of the flight out, barely able to move, having had a few good months until then. Bunged my dose up

We will see....but if it performs well, man, it's another proof of the concept. For example, check a company called InSilico and you will see how many big pharma companies are using their AI/ML services to develop their own solutions... Anyway...a clinical trial is soon to begin evaluating Pocenbrodib

I appreciate this may be trivial in the face of other posts on here but I'd appreciate any thoughts you may have. I take statins & Clopidogrel following a slight stroke 10 years ago. My dentists have advised I should keep taking both ahead of having 2 teeth out. They will apply stitches at the removal

Hello, I purchased this white paper, but not sure I can share online. If you send me a message, I'll forward you the PDF. Here is the summary online: https://acsjournals.onlinelibrary.wiley.com/doi/10.1002/cncr.35559 After reading this paper, I'm going to take a more aggressive approach to my cardiac

I am a carer for someone on oxygen 24/7.She has not been to the dentist for some time now and has a couple of possibly broken teeth. I have tried one dentist who advises that she would have to come off oxygen for treatment. She could for a maximum of 20 minutes but if the treatment was to be longer,

Hi looking for advice. I am currently waiting on confirmed diagnosis of anca vasculitis but based on my symptoms and anti-mpo test it looks like I have it. I am on prednisolone but also rivaroxiban as I had a pulmonary embolism recently. I have had a bad reaction to iron infusion that caused calcium

If I am posting what has already been posted I do apologise I tried to search the forum but couldn't come up with anything I hope the new year is good to all of you on this forum ...I dont often post but reading what is happening out there really helps it is so informative ... keeps me sane Both myself

For anyone who missed posts by Joolsg and SueJohnson about AASM's drafting work last year, there is a new Clinical Practice Guideline from the AASM advising against the use of dopamine agonists for RLS except in some exceptional circumstances, strongly recommending iron therapy, and advising for gabapentinoids

Life long sufferer here. Currently on low dose opioids after trying everything else under the sun. I have things pretty much under control except for when I am in a situation where I cannot move about... specifically airplanes. I get massive RLS and panic attacks.. I do deep breathing, listen to

After 14 years on dopamine agonists (first ropinerole and now pramipexole) and the inevitable augmentation, I have been tapering off of pramipexole since last April. I am under the care of a neurologist who is educated about DAs and augmentation. I was taking 1 mg of pramipexole last April and am currently

Hello All, I have been living with RLS since 2018—not continuously, but in waves lasting a few weeks, followed by breaks before it returns. I haven't identified the trigger. I've tested nearly all the medications mentioned in this forum, except for strong opioids, but with no clear or definitive results

Sorry to hear so much pain for you. I can't take anything with codeine, but paracetamol has a good antiinflammatory outcome, so worth a try.I'm not sure where the Omeprazole fits in, unless it's to protect your oesophagus from any opioids. Sorry I can't help further, but wish you well. Keep posting us

Hi all, relatively new to the forum and just wondered if any might have advice on the best next step I'm 33 living in NZ I've had RLS on and off maybe once in a blue moon since I was a teenager but over the last year there was a huge escalation in symptoms. I believed this was due to amitriptyline

I’ve just come off the phone with my GP who is notorious for sticking to the guidelines. I discussed coming off pramipexole completely. He refused to help with iron infusions or even supplements, I was told to buy my own. He also refused to prescribe me anything to help with coming off them ie opioids

Sorry this is so long. I am looking for advice from you all. In 2021 I was given buprenorphine (by Dr. B in California- I am in Arizona) to come off .5 mg ropinerole. I was on 1 mg ropinerole for over 15 years. I successfully (with much difficulty) withdrew from it but after almost a month had such severe

Title: current investigational therapies in the treatment of RLS. I caught some of it in between doing the school run and getting myself to work but didn't catch it all (I'm not an RLS foundation member so can't watch the catch up version). I heard Dr Berkowski speak about mainstream treatments (gabapentinoids

So last June I had a flare-up on my knee and it has never gone away. I had gone to see the consultant who then gave me an injection so a week later it was still as bad. He said he would get me to go for an emergency scan. Also last year I was having problems with my throat. I cannot take strong painkillers

Hi guys! I recently had the mirena coil fitted 5 months ago to help with my endometriosis, I reacted to it terribly and have been suffering with acne, weight gain and mood issues (i already have pmdd!). It didnt actually effect my periods at all they are still as bad as they were, so pretty useless.

Hello I have some nerve pain from bones spurs trapping nerves in neck and back. 80% of the time the nerve pain is on the mild side with short but sometimes frequent bursts of more intense pain like being stabbed with a needle. I take opioids to manage the general axial neck pain when needed but my