Drug combination: I've been taking... - Restless Legs Syn...

Restless Legs Syndrome

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Drug combination

Believer1234 profile image
5 Replies

I've been taking 900mg of gabapentin with extremely limited success. I've not had any joy to date in getting opioids prescribed. My partner had some Codeine from a recent hospital stay and I've started taking this as a trial. To date (and it's early days) it seems to have been a game changer and I've been getting some decent sleep. I find the best combination is 600mg of Gaba and 30mg of Codeine. However I've read that you should not take these drugs together as they both work on the CNS and can cause extreme drowsiness, difficulties breathing, coma and death! 😮. However I don't feel drowsy at all - I haven't felt this good in a long time due to getting some good sleep! No breathing difficulties either and I'm still working out. Does anyone have any experience of taking the 2 drugs together? Thank you 🙂

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Believer1234
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SueJohnson profile image
SueJohnson

If you haven't had any breathing difficulties or extremely sleepiness I wouldn't worry about it.

I'm glad you have found something that works.

Believer1234 profile image
Believer1234 in reply toSueJohnson

Thanks Sue. The battle now is getting it on prescription ☹️

Joolsg profile image
Joolsg

There was a study linking gabapentin and opioids to respiratory depression. But usually only in those with pre existing respiratory issues.You should now push for codeine on prescription.

The new NICE cks guidance sets out that an opioid can be prescribed.

Are you taking gabapentin in split doses 2 hours apart?

Islay9 profile image
Islay9

I take them together.

Previously I was prescribed dihydrocodeine after an operation and they knew I was on a high dose of gabapentin. I’m now on a higher dose of dihydrocodeine plus a high dose of pregabalin.

I agree the codeine is a game changer (for some).

Believer1234 profile image
Believer1234 in reply toIslay9

Thank you 🙂

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