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A study record is now available on the Clinical Trials website for the big (N=330) Ambroxol Phase 3 trial (NCT05778617)
Recruitment Status: Not yet recruiting Estimated Study Start Date: September 2023 Estimated Study Completion Date: September 2028 Each participant will be taking ambroxol [or placebo] for two years, and it is estimated that it will take two years to recruit 330 PwPs. Ambroxol to Slow Progression
Recruitment Status: Not yet recruiting Estimated Study Start Date: September 2023 Estimated Study Completion Date: September 2028 Each participant will be taking ambroxol [or placebo] for two years, and it is estimated that it will take two years to recruit 330 PwPs. Ambroxol to Slow Progression
jeffreyn
in
Cure Parkinson's
1 year ago
Pregnant and just had 2nd pyschosis
Dear All, Firstly I want to say how sorry I am for some of my posts a few weeks ago, I had another psychotic episode in which I found out I was pregnant and thought the baby was from God and I was helping save the world. Anyway, I feel like I am living in a nightmare. I have three children and I now
Dear All, Firstly I want to say how sorry I am for some of my posts a few weeks ago, I had another psychotic episode in which I found out I was pregnant and thought the baby was from God and I was helping save the world. Anyway, I feel like I am living in a nightmare. I have three children and I now
Control1234
in
Action on Postpartum Psychosis
1 year ago
rant to feel better?
I have been thinking a lot lately about the different path my life could have taken. I’m 32 and I have a 16 year old son. A 21 year old adult man got me pregnant when I was 15. My religious parents never spoke a single word to me about safe sex, and decided without me that I would have this baby.
I have been thinking a lot lately about the different path my life could have taken. I’m 32 and I have a 16 year old son. A 21 year old adult man got me pregnant when I was 15. My religious parents never spoke a single word to me about safe sex, and decided without me that I would have this baby.
Cuprea
in
Anxiety and Depression Support
1 year ago
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Am I alone? I don't feel like doctors understand how serious I am.
For a year now. Literally a year, I jave been struggling with extreme anxiety and depression. I am just curious if others have these things non stop. And for so long. It starts when I wake up, and doesn't end until I have taken seroquel at night for sleep. So I get about 45 minutes to an hour before
For a year now. Literally a year, I jave been struggling with extreme anxiety and depression. I am just curious if others have these things non stop. And for so long. It starts when I wake up, and doesn't end until I have taken seroquel at night for sleep. So I get about 45 minutes to an hour before
Twistedopher
in
Anxiety and Depression Support
1 year ago
first time here-First post
Hi everyone. I have been on my health journey for many years through counseling for things like anger and depression. I have been fairly successful in my life and have overcome much. I raised a family and was able to cope with anxiety. But after my divorce, anxiety took root and intensified. It’s been
Hi everyone. I have been on my health journey for many years through counseling for things like anger and depression. I have been fairly successful in my life and have overcome much. I raised a family and was able to cope with anxiety. But after my divorce, anxiety took root and intensified. It’s been
JustRide
in
Anxiety and Depression Support
1 year ago
Bowel irrigation (Not "colonic irrigation")
I have obstructed defecation (anismus) which has not responded to biofeedback etc. The next step is at home bowel irrigation and I am just waiting for an appointment with the bowel nurse to issue me with the equipment. It would be helpful to hear of anyone`s experience with this. I don`t know which
I have obstructed defecation (anismus) which has not responded to biofeedback etc. The next step is at home bowel irrigation and I am just waiting for an appointment with the bowel nurse to issue me with the equipment. It would be helpful to hear of anyone`s experience with this. I don`t know which
janke
in
IBS Network
1 year ago
Does Buspirone take time to work
I moved the actual question to the front. Lol. Too much rant. My question is: If any of you take buspirone, what were You told, please, as far as how it works? This is kind of a "poll" for my arsenal, not something I intend to use as medical advice. ***Were you told it takes awhile to work, and
I moved the actual question to the front. Lol. Too much rant. My question is: If any of you take buspirone, what were You told, please, as far as how it works? This is kind of a "poll" for my arsenal, not something I intend to use as medical advice. ***Were you told it takes awhile to work, and
Hidden
in
Anxiety and Depression Support
1 year ago
Need help please to manage one more sympton
Thank you collogues, for your sharings, that have helped me physically, emotionally and mentally. I am a 70-year-old male diagnosed with PD last Nov 22. After trial and error with some medicines, I settled, from early Jan 23, on Sifrol with 6 tablets per day (0.18mg). This produced the magic I was praying
Thank you collogues, for your sharings, that have helped me physically, emotionally and mentally. I am a 70-year-old male diagnosed with PD last Nov 22. After trial and error with some medicines, I settled, from early Jan 23, on Sifrol with 6 tablets per day (0.18mg). This produced the magic I was praying
michelbekhazi
in
Cure Parkinson's
1 year ago
Subacute thyroiditis and sub clinical hypothyroidism
Hello, just asking for your opinion on whether I should start treatment or not for sub clinical hypothyroidism after subacute thyroiditis. I'm now it seems in the hypothyroid phase of this horrible illness ( subacute thyroiditis is like the gift that keeps on giving!) after becoming ill in October with
Hello, just asking for your opinion on whether I should start treatment or not for sub clinical hypothyroidism after subacute thyroiditis. I'm now it seems in the hypothyroid phase of this horrible illness ( subacute thyroiditis is like the gift that keeps on giving!) after becoming ill in October with
Julietilly22
in
Thyroid UK
1 year ago
Low Dose Ketamine
Has anyone tried treating your depression and anxiety with low dose Ketamine through a telehealth company? I have tried just about every antidepresant there is with only moderate success. I have been wanting to give Ketamine a try but I was uncomfortable with the psychedelic experiences and high cost
Has anyone tried treating your depression and anxiety with low dose Ketamine through a telehealth company? I have tried just about every antidepresant there is with only moderate success. I have been wanting to give Ketamine a try but I was uncomfortable with the psychedelic experiences and high cost
Scott1951
in
Anxiety and Depression Support
1 year ago
Really getting tired of this
I have very recently started having panic attacks. I have been on Buspirone 15mg 2x daily for about 6 weeks and feel like I need to increase. I have now realize that I’m afraid of everything. I used to be a strong independent person, now I can’t stand to be alone, I’m fearful about doing things I once
I have very recently started having panic attacks. I have been on Buspirone 15mg 2x daily for about 6 weeks and feel like I need to increase. I have now realize that I’m afraid of everything. I used to be a strong independent person, now I can’t stand to be alone, I’m fearful about doing things I once
Frogeyes
in
Anxiety and Depression Support
1 year ago
Graduated, celebrated, but now back to reality
So yesterday was the exam. Took it with A, prof even said my paper was best, saw friends, was ecstatic, went to the club because apparently we don't have a prom or anything. But the morning i got back, took a shower, tried to sleep, my hair still wet, worried if i got myself sick, a lot of anxiety. Couldn't
So yesterday was the exam. Took it with A, prof even said my paper was best, saw friends, was ecstatic, went to the club because apparently we don't have a prom or anything. But the morning i got back, took a shower, tried to sleep, my hair still wet, worried if i got myself sick, a lot of anxiety. Couldn't
Against_the_current
in
Anxiety and Depression Support
1 year ago
My Current Stack (What is in Yours?)
Fabnusasked me what my current stack was so I am sharing it here. Please remember I have not been diagnosed with PD. I have RBD and some other symptoms.
Also remember I have a HS degree, poor impulse control, and I am prone to bad decisions. Please do your own research.
The best place
Fabnusasked me what my current stack was so I am sharing it here. Please remember I have not been diagnosed with PD. I have RBD and some other symptoms.
Also remember I have a HS degree, poor impulse control, and I am prone to bad decisions. Please do your own research.
The best place
Bolt_Upright
in
Cure Parkinson's
1 year ago
cure parkinsons
I HAVE BEEN DIAGNOSED WITH PARKINSONS IN 2018. I LOOKING TO GAIN KNOWLEDGE OF NEW TREATMENTS. CURRENTLY EVALUATING WHITE LIGHT AND RED LIGHT THERAPIES. ANYONE USING THESE THERAPIES PLEASE SHARE YOUR EXPERIENCES.
I HAVE BEEN DIAGNOSED WITH PARKINSONS IN 2018. I LOOKING TO GAIN KNOWLEDGE OF NEW TREATMENTS. CURRENTLY EVALUATING WHITE LIGHT AND RED LIGHT THERAPIES. ANYONE USING THESE THERAPIES PLEASE SHARE YOUR EXPERIENCES.
Alan1949
in
Cure Parkinson's
1 year ago
Citalapram versa escitalopram
I am still trying to find which of about have theLeast side effects. I don't want emotional blunting or horrible numbing of important feelings. Weight gain Citalapram seem to have least on here HU But I've read studies escitalopram has less side effects. Are either hard to come off . Ladies in 60's
I am still trying to find which of about have theLeast side effects. I don't want emotional blunting or horrible numbing of important feelings. Weight gain Citalapram seem to have least on here HU But I've read studies escitalopram has less side effects. Are either hard to come off . Ladies in 60's
Chi1504
in
Anxiety and Depression Support
1 year ago
Prednislone and Anxiety
I've been reducing from 20mg pred since November 2022, currently on 11mg. Since Christmas I have had episodes of extreme anxiety, depression, mood swings and tearfulness. My Rheumy this morning suggested swapping to Betamethasone which does not cross the blood/brain barrier. However, when I researched
I've been reducing from 20mg pred since November 2022, currently on 11mg. Since Christmas I have had episodes of extreme anxiety, depression, mood swings and tearfulness. My Rheumy this morning suggested swapping to Betamethasone which does not cross the blood/brain barrier. However, when I researched
FleetRose
in
PMRGCAuk
1 year ago
Rasagiline: The Neuroprotective Activities of the Novel Multi-Target Iron-Chelators in Models of Alzheimer’s Disease, ALS and Aging
https://www.mdpi.com/2073-4409/12/5/763/html However, accumulating evidence has shown that iron-dependent oxidative stress (OS), increased iron levels, and monoamine oxidase (MAO)-B activity, as well as reduced antioxidant levels and activities in the brain, maybe major pathogenic factors in neurodegenerative
https://www.mdpi.com/2073-4409/12/5/763/html However, accumulating evidence has shown that iron-dependent oxidative stress (OS), increased iron levels, and monoamine oxidase (MAO)-B activity, as well as reduced antioxidant levels and activities in the brain, maybe major pathogenic factors in neurodegenerative
Hidden
in
Cure Parkinson's
1 year ago
???s @ dalfampridine/Ampyra
saw Neuro yesterday. She’s prescribing Ampyra. I’m hopeful 🤞 but wondered what others experiences were? What benefits, side effects? Insomnia? Thanks! 😊
saw Neuro yesterday. She’s prescribing Ampyra. I’m hopeful 🤞 but wondered what others experiences were? What benefits, side effects? Insomnia? Thanks! 😊
erash
in
My MSAA Community
1 year ago
Exercise
Hiam in a sensitized nervouse system and some say excercising makes them worse as excercise is still stress on the body do some I know if u have normal anxiety excercise is great but what if u are highly sensitized can anyone share
Hiam in a sensitized nervouse system and some say excercising makes them worse as excercise is still stress on the body do some I know if u have normal anxiety excercise is great but what if u are highly sensitized can anyone share
moggie8
in
Anxiety Support
1 year ago
Do I really hate my degree or is it just mental health?
Hi all. For some background: anxiety and depression diagnosis and suspected Bipolar Type 2. Currently not medicated while getting access to mood stabilisers. I used to be an active student (STEM major) with excellent grades, but the past few months I can see a steady decline in my performance and generally
Hi all. For some background: anxiety and depression diagnosis and suspected Bipolar Type 2. Currently not medicated while getting access to mood stabilisers. I used to be an active student (STEM major) with excellent grades, but the past few months I can see a steady decline in my performance and generally
fatiguei
in
Anxiety and Depression Support
1 year ago
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