A study record is now available on the Cl... - Cure Parkinson's

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A study record is now available on the Clinical Trials website for the big (N=330) Ambroxol Phase 3 trial (NCT05778617)

jeffreyn profile image
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Recruitment Status: Not yet recruiting

Estimated Study Start Date: September 2023

Estimated Study Completion Date: September 2028

Each participant will be taking ambroxol [or placebo] for two years, and it is estimated that it will take two years to recruit 330 PwPs.

Ambroxol to Slow Progression in Parkinson Disease (ASPro-PD):

clinicaltrials.gov/ct2/show...

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jeffreyn
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limcheeese22 profile image
limcheeese22

why would they take so long to complete?? 2028??

jeffreyn profile image
jeffreyn in reply tolimcheeese22

"Each participant will be taking ambroxol [or placebo] for two years, and it is estimated that it will take two years to recruit 330 PwPs."

Plus maybe one year to analyze the data and publish the results?

I'm going to register for this one if I can. I have faith in the team, its got a 6 month open label phase so even the placebo group gets to try it, and big pharma is out of the loop so if it proves to be a usable modality the price will not be hiked up. For those that haven't seen the update, I've attached below. Dare we hope?

youtu.be/xdYmaJ-yQy8

Nickcc profile image
Nickcc

bloody ridiculous that we have to wait 3 years for a drug that has been available over the counter for years and which phase 2 trials have confirmed have no side effects and help slow PD.

Stillstandingstill profile image
Stillstandingstill in reply toNickcc

It is frustrating, but the doses are much bigger than the previous prescribed use. Hopefully things will move faster if they can recruit quickly. I feel your pain though. Time is brain for those of us waiting and trying to keep in a holding pattern.

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