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Linagliptin / Metformin
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Enzalutamide NFG* for me. Clinical trials beckon.
* NFG = No good. I finished up 9 cycles of docetaxal in July in a chemo-resistant state and started on Enzalutamide. Unfortunately Enza has done absolutely nothing. No impact on disease progression at all. I remain on Zolodex of course and MO added metformin and statins to my cocktail of drugs to
* NFG = No good. I finished up 9 cycles of docetaxal in July in a chemo-resistant state and started on Enzalutamide. Unfortunately Enza has done absolutely nothing. No impact on disease progression at all. I remain on Zolodex of course and MO added metformin and statins to my cocktail of drugs to
Hazard
in
Advanced Prostate Cancer
6 years ago
Metformin mitochondria PD
Commentary: Metformin reverses TRAP1 mutation-associated alterations in mitochondrial function in Parkinson's disease. Sachchida N. Rai, Saumitra S. Singh, [...], and Surya P. Singh. 2018. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6079192/
Commentary: Metformin reverses TRAP1 mutation-associated alterations in mitochondrial function in Parkinson's disease. Sachchida N. Rai, Saumitra S. Singh, [...], and Surya P. Singh. 2018. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6079192/
aspergerian
in
Cure Parkinson's
6 years ago
TMI nut period talk!
When I first started my period when I was about 9-10 they was really heavy but had no pain, some days I would forget I’m on my period because I had no pain and never suffered from PMS after losing my virginity my period would come every month but on different days but I’ve notice for over a year how
When I first started my period when I was about 9-10 they was really heavy but had no pain, some days I would forget I’m on my period because I had no pain and never suffered from PMS after losing my virginity my period would come every month but on different days but I’ve notice for over a year how
GemGem95
in
Endometriosis UK
6 years ago
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Update: dramatic response from the chemotherapy
Here's my update at last. In August 2018 I finished Docetaxel chemotherapy (6 courses) while being on ADT. Below is a quick rundown from start till now. The initial PCa DX was done in March, 2018. Prior to it mostly unrecognized symptoms gradually increased over the course of 2-3 months included pain
Here's my update at last. In August 2018 I finished Docetaxel chemotherapy (6 courses) while being on ADT. Below is a quick rundown from start till now. The initial PCa DX was done in March, 2018. Prior to it mostly unrecognized symptoms gradually increased over the course of 2-3 months included pain
henukit
in
Advanced Prostate Cancer
6 years ago
First official meeting with oncologist!
Hello All, Today I take my father to his oncologist to discuss treatment options. He is already on Casodex and Lupron from his urologist and the oncologist mentioned chemo treatments but have yet to solidify official treatment plan. I have created a few beginner questions to go over with oncologist
Hello All, Today I take my father to his oncologist to discuss treatment options. He is already on Casodex and Lupron from his urologist and the oncologist mentioned chemo treatments but have yet to solidify official treatment plan. I have created a few beginner questions to go over with oncologist
Here4Dad
in
Advanced Prostate Cancer
6 years ago
weigh in update
bad week had a few days with really low blood sugar so was having to eat everything in site to get them up again, i shouldnt be having lows as type 2 i explained what happened to consultant and that i was expecting a gain got on scales and gained 2lb i was ok with that now im prepared for if i go low
bad week had a few days with really low blood sugar so was having to eat everything in site to get them up again, i shouldnt be having lows as type 2 i explained what happened to consultant and that i was expecting a gain got on scales and gained 2lb i was ok with that now im prepared for if i go low
mandy72
in
Thyroid UK
6 years ago
Metformin
Anyone else on Metformin for PCOS? I've just started taking it (last Saturday) so coming to the end of Week 1 and I haven't lost a single pound! I've not gained either but I thought this was meant to help lose weight? I will say that I've not had the usual side effects everyone talks about, I'm constipated
Anyone else on Metformin for PCOS? I've just started taking it (last Saturday) so coming to the end of Week 1 and I haven't lost a single pound! I've not gained either but I thought this was meant to help lose weight? I will say that I've not had the usual side effects everyone talks about, I'm constipated
Mouse87
in
PCOS UK (Verity)
6 years ago
Am I menopausal?
For the past few days, I’ve been having really bad hot flashes. I have been having an issue with sweating. I’m only 23 years of age and have type 2 diabetes that is controlled by taking metformin slow release.
For the past few days, I’ve been having really bad hot flashes. I have been having an issue with sweating. I’m only 23 years of age and have type 2 diabetes that is controlled by taking metformin slow release.
GemGem95
in
Diabetes Research & Wellness Foundation
6 years ago
Fibroscan vs Fibrotest
Hello, my name is Maria I'm a 26year old female new here. I have had the pleasure of reading some posts and so forth but figured I'd post since I have quite a few questions myself and was wondering if anyone had any kind of insight. 😊 *Warning very lengthy* So on August 2nd 2018 I went to see my primary
Hello, my name is Maria I'm a 26year old female new here. I have had the pleasure of reading some posts and so forth but figured I'd post since I have quite a few questions myself and was wondering if anyone had any kind of insight. 😊 *Warning very lengthy* So on August 2nd 2018 I went to see my primary
Oscarala
in
British Liver Trust
6 years ago
Ovasitol side effects
Hi so I'm taking ovasitol which is seems to be having an effect on my bowels. I've been taking it now for around a month so I would have thought it would have settled it hasn't. sorry tmi but my poo is bile coloured and fragmented all the time now i googled about the bile bit and read metformin can cause
Hi so I'm taking ovasitol which is seems to be having an effect on my bowels. I've been taking it now for around a month so I would have thought it would have settled it hasn't. sorry tmi but my poo is bile coloured and fragmented all the time now i googled about the bile bit and read metformin can cause
nettiboo1982
in
PCOS UK (Verity)
6 years ago
More bad news
Seems like all we get is bad news. 4wks ago I posted how my dad’s PSA went from 3.5 to 10 in 4wks after being switched from Zytiga to Xtandi (Zytiga failed at 7 months). Well today we found out his PSA is at 20-it has doubled in 4wks. His alkaline phosphotase has increased and his calcium level is sky
Seems like all we get is bad news. 4wks ago I posted how my dad’s PSA went from 3.5 to 10 in 4wks after being switched from Zytiga to Xtandi (Zytiga failed at 7 months). Well today we found out his PSA is at 20-it has doubled in 4wks. His alkaline phosphotase has increased and his calcium level is sky
Hidden
in
Advanced Prostate Cancer
6 years ago
New member
Hello everyone. I was recently diagnosed as being diabetic. My doctor prescribesd Metformin 1 pill (500mg) with breakfast and 1 with dinner. Does Metformin affect the ability of a man to ejaculate? I take 2-3 20mg Viagra pills before sex. Prior to starting Metformin I could ejaculate twice per week
Hello everyone. I was recently diagnosed as being diabetic. My doctor prescribesd Metformin 1 pill (500mg) with breakfast and 1 with dinner. Does Metformin affect the ability of a man to ejaculate? I take 2-3 20mg Viagra pills before sex. Prior to starting Metformin I could ejaculate twice per week
Alphonso2018
in
Men's Health Forum
6 years ago
Hello
I’m a new member. Does Metformin effect the ability of a man to ejaculate? I’m 70 years old.
I’m a new member. Does Metformin effect the ability of a man to ejaculate? I’m 70 years old.
Alphonso2018
in
Men's Health Forum
6 years ago
Cirrhosis makes me sleep all day & night -- any remedies?
Hi! I'm new here. I have had NASH for many years and it has now turned into cirrhosis. I have numerous varices, and had a near-fatal episode of bleeding from my varices a few years ago. The varices have responded well to banding, but I am now astonishingly tired. Sleeping 18 to 22 hours a day is not
Hi! I'm new here. I have had NASH for many years and it has now turned into cirrhosis. I have numerous varices, and had a near-fatal episode of bleeding from my varices a few years ago. The varices have responded well to banding, but I am now astonishingly tired. Sleeping 18 to 22 hours a day is not
RosaRugosa
in
Liver4Life
6 years ago
Hello all I am type 2 for about a year now
My doctor started me on metformin 4 tabs a day and Victoza 1.8 a day. I have lost some weight and have been feeling great. So, at 6 months, they lowered the metformin dose to 2 tabs a day and kept Victoza the same. Still feeling great and a1c is great. So they just took my Victoza down to .6. Not
My doctor started me on metformin 4 tabs a day and Victoza 1.8 a day. I have lost some weight and have been feeling great. So, at 6 months, they lowered the metformin dose to 2 tabs a day and kept Victoza the same. Still feeling great and a1c is great. So they just took my Victoza down to .6. Not
Vicky68
in
Diabetes Research & Wellness Foundation
6 years ago
Concrete Solutions to Fasting Blood Sugar (Dawn Phenomena)
While i am aware of the Dawn phenomenon and have read articles regarding the same here , i have yet not been able to help myself to reduce my FBS. my BS normaly average's between 135 to 150 post meals (Breakfast, Lunch , dinner ) but my FBS invariably ranges between 145 to 165. for eg. last night my
While i am aware of the Dawn phenomenon and have read articles regarding the same here , i have yet not been able to help myself to reduce my FBS. my BS normaly average's between 135 to 150 post meals (Breakfast, Lunch , dinner ) but my FBS invariably ranges between 145 to 165. for eg. last night my
Gmore
in
Diabetes India
6 years ago
Metformin depletes Vitamin B12 and Coq10
Metformin is the first line of defence for Diabetes. It is the old workhorse and perhaps it is the only diabetic medicine which has least side effects. While going through this beautiful article on " Drug induced nutrient Depletion" which is highly relevant to all diabetes, metformin is listed as depleting
Metformin is the first line of defence for Diabetes. It is the old workhorse and perhaps it is the only diabetic medicine which has least side effects. While going through this beautiful article on " Drug induced nutrient Depletion" which is highly relevant to all diabetes, metformin is listed as depleting
namaha
Administrator
in
Diabetes India
6 years ago
lchf mixed diet
i am following lchf diet. mixing of carbohydrate say one chappathi at dinner etc may cause marked change in blood sugar.i mean our energy source is from fat and protien metabolism or glucose.metabolism will prevail?i am diebetic sincr 35 yeras aged 69 using 3 times actrapid and one time lantus with one
i am following lchf diet. mixing of carbohydrate say one chappathi at dinner etc may cause marked change in blood sugar.i mean our energy source is from fat and protien metabolism or glucose.metabolism will prevail?i am diebetic sincr 35 yeras aged 69 using 3 times actrapid and one time lantus with one
carahman2003
in
Diabetes India
6 years ago
Dad declining fast
Two weeks ago my dad found out that his PSA jumped from 3.5 to 10 in four weeks on Xtandi. He had only been on Xtandi for four weeks he was switched over from Zytiga. In this past week he has declined rapidly complaining of his back and legs hurting, severe restless leg syndrome, not sleeping at all,
Two weeks ago my dad found out that his PSA jumped from 3.5 to 10 in four weeks on Xtandi. He had only been on Xtandi for four weeks he was switched over from Zytiga. In this past week he has declined rapidly complaining of his back and legs hurting, severe restless leg syndrome, not sleeping at all,
Hidden
in
Advanced Prostate Cancer
6 years ago
WARNING ⚠️ SENSITIVE POST
Hi all you lovely ladies. I hope you are taking care of yourselves on this tough journey. I’ve thought long and hard about whether to post this and really hope that I don’t upset or offend anyone. I know when I was in a dark place with this journey there were times when certain posts would feel like
Hi all you lovely ladies. I hope you are taking care of yourselves on this tough journey. I’ve thought long and hard about whether to post this and really hope that I don’t upset or offend anyone. I know when I was in a dark place with this journey there were times when certain posts would feel like
NsKaz
in
Fertility Network UK
6 years ago
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