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Phase 2 Clinical Trial of DopaFuse Delivery System
The DopaFuse Delivery System is a patented, intra-oral system that continuously and noninvasively delivers levodopa and carbidopa at a controlled rate for patients with PD. The DopaFuse System consists of an oral retainer, its case, and a prefilled, single-use drug container that continuously releases
The DopaFuse Delivery System is a patented, intra-oral system that continuously and noninvasively delivers levodopa and carbidopa at a controlled rate for patients with PD. The DopaFuse System consists of an oral retainer, its case, and a prefilled, single-use drug container that continuously releases
Farooqji
in
Cure Parkinson's
2 years ago
Mucuna + carbidopa = vomiting? What's going on? Help please!
As I've mentioned elsewhere, I normally take Barlowe's Brown Indian Mucuna instead of Sinemet (VERY bad reaction to Sinemet which got worse over time when I tried it for a few months in early 2021). The Barlowe's capsules are 650 mg extract with 40% L-Dopa, so approximately 260 mg L-Dopa each. I take
As I've mentioned elsewhere, I normally take Barlowe's Brown Indian Mucuna instead of Sinemet (VERY bad reaction to Sinemet which got worse over time when I tried it for a few months in early 2021). The Barlowe's capsules are 650 mg extract with 40% L-Dopa, so approximately 260 mg L-Dopa each. I take
1LittleWillow
in
Cure Parkinson's
2 years ago
Mucuna Pruriens
I would appreciate some advice on the following. I recently started giving Mucuna Pruriens to my wife hoping to start reducing her usual dopamine medication and replace this with the natural L-Dopa that Mucuna has as this should have far less side effects. However, after the third day, I stopped
I would appreciate some advice on the following. I recently started giving Mucuna Pruriens to my wife hoping to start reducing her usual dopamine medication and replace this with the natural L-Dopa that Mucuna has as this should have far less side effects. However, after the third day, I stopped
Rafiki2
in
Cure Parkinson's
2 years ago
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Medication for PSP
I would like to discuss with anyone else who has my symptoms and is taking my medication. Carbidopa and Levodopa and Amantadine
I would like to discuss with anyone else who has my symptoms and is taking my medication. Carbidopa and Levodopa and Amantadine
Zarzuela
in
PSP Association
2 years ago
Ketamine?
Levodopa, a standard Parkinson’s therapy, is a precursor molecule that is converted to dopamine in the brain. It is well-known for controlling Parkinson’s disease symptoms such as rigidity and slowness of movement. However, prolonged use of levodopa may result in spontaneous involuntary movements
Levodopa, a standard Parkinson’s therapy, is a precursor molecule that is converted to dopamine in the brain. It is well-known for controlling Parkinson’s disease symptoms such as rigidity and slowness of movement. However, prolonged use of levodopa may result in spontaneous involuntary movements
kaypeeoh
in
Cure Parkinson's
2 years ago
constipation
Hi folks Taking Levodopa Gabapentin and Tramadol for Parkinson and Restless legs and get bad constipation can you suggest any good things to take to help this .
Hi folks Taking Levodopa Gabapentin and Tramadol for Parkinson and Restless legs and get bad constipation can you suggest any good things to take to help this .
auldreekie18
in
Restless Legs Syndrome
2 years ago
Call for a more complete vitamins blood testing, especially b6.
I would have preferred to write about my coping with PD at a later stage, but in view of recent events I would like to warn you about the possible consequences of incomplete examination. After being diagnosed 1.5 years ago at 65, I found the development of the disease to be (too) fast. There is still
I would have preferred to write about my coping with PD at a later stage, but in view of recent events I would like to warn you about the possible consequences of incomplete examination. After being diagnosed 1.5 years ago at 65, I found the development of the disease to be (too) fast. There is still
Esperanto
in
Cure Parkinson's
2 years ago
Vitamin B1 Therapy
Is anyone on the high dosage of vitamin B1 therapy and for those who are, are you also taking any meds for Parkinson's like "Levodopa"?
Is anyone on the high dosage of vitamin B1 therapy and for those who are, are you also taking any meds for Parkinson's like "Levodopa"?
Rafyaz
in
Cure Parkinson's
2 years ago
6 Important Supplements To Fight Peripheral Neuropathy
People with Parkinson's disease (PwP) are at increased risk for getting Peripheral Neuropathy (PN). PN can have many causes. Multiple causes other than PD such as diabetes, insulin resistance or certain chemotherapy agents can also cause PN. The main consideration is that the nerves are being damaged
People with Parkinson's disease (PwP) are at increased risk for getting Peripheral Neuropathy (PN). PN can have many causes. Multiple causes other than PD such as diabetes, insulin resistance or certain chemotherapy agents can also cause PN. The main consideration is that the nerves are being damaged
chartist
in
Cure Parkinson's
2 years ago
Parkinson and narrow angle glaucoma
Hi, I have been suffering from Parkinson's and have been taking the following medications: Pacitane Tablet - SALT COMPOSITION Trihexyphenidyl (2mg) Sinemet 250mg/25mg Tablet - SALT COMPOSITION Levodopa (250mg) + Carbidopa (25mg) I have been recently diagnosed with narrow angle glaucoma in one of
Hi, I have been suffering from Parkinson's and have been taking the following medications: Pacitane Tablet - SALT COMPOSITION Trihexyphenidyl (2mg) Sinemet 250mg/25mg Tablet - SALT COMPOSITION Levodopa (250mg) + Carbidopa (25mg) I have been recently diagnosed with narrow angle glaucoma in one of
drmittal
in
Cure Parkinson's
2 years ago
My disastrous MRI guided FUS PTT
I had the surgery at Sonimodul in Switzerland in Feb 2021. Short story: Before PTT, I took 3 x Levodopa Carbidopa CR daily. Now, I take 5 and my symptoms are a lot worse. Progression rate has increased. Long story: I never had resting tremors. I have rigidity, dystonia, bradykinesia, akinesia
I had the surgery at Sonimodul in Switzerland in Feb 2021. Short story: Before PTT, I took 3 x Levodopa Carbidopa CR daily. Now, I take 5 and my symptoms are a lot worse. Progression rate has increased. Long story: I never had resting tremors. I have rigidity, dystonia, bradykinesia, akinesia
Parkie-
in
Cure Parkinson's
2 years ago
is l dopa toxic?
https://www.youtube.com/watch?v=k703Shlgkhw
https://www.youtube.com/watch?v=k703Shlgkhw
Solvang53
in
Cure Parkinson's
2 years ago
Parkinson
I now have Parkinson as well as restless legs ,am on Levodopa 100mg/5Omg at 11.OO am -3.00pm -7.OOpm -11.OOpm capsules only last 3-4 hours waken at 3.OOam in morning with restless legs on and off till getting up at 8.OOam for breakfast . Consultant phoning this week to see how I am getting on she will
I now have Parkinson as well as restless legs ,am on Levodopa 100mg/5Omg at 11.OO am -3.00pm -7.OOpm -11.OOpm capsules only last 3-4 hours waken at 3.OOam in morning with restless legs on and off till getting up at 8.OOam for breakfast . Consultant phoning this week to see how I am getting on she will
auldreekie18
in
Restless Legs Syndrome
2 years ago
Role of the adrenals in my tremor and dopamine deficiency
I am wondering if I am alone in being aware of the connection between my adrenals and my dopamine deficiency and resulting tremors. I’d appreciate all feedback, whether academic or incidental. Firstly, I definitely have a dopamine deficiency because my dexterity can return to perfect for the small windows
I am wondering if I am alone in being aware of the connection between my adrenals and my dopamine deficiency and resulting tremors. I’d appreciate all feedback, whether academic or incidental. Firstly, I definitely have a dopamine deficiency because my dexterity can return to perfect for the small windows
Meg024
in
Cure Parkinson's
2 years ago
“How Does Deep Brain Stimulation Change the Course of Parkinson's Disease?”
This very recent (May 2022) review was posted elsewhere (FB) and after reading it myself (it's open access) I thought it worth re-posting here on HU - for those interested in learning more on long-term DBS outcomes. https://movementdisorders.onlinelibrary.wiley.com/doi/10.1002/mds.29052?fbclid=IwAR3EaJVE5QUEQ165u7wKsneu2V3JHhs36YuQCiRHxjSrbhUXHTkr31qCafU
This very recent (May 2022) review was posted elsewhere (FB) and after reading it myself (it's open access) I thought it worth re-posting here on HU - for those interested in learning more on long-term DBS outcomes. https://movementdisorders.onlinelibrary.wiley.com/doi/10.1002/mds.29052?fbclid=IwAR3EaJVE5QUEQ165u7wKsneu2V3JHhs36YuQCiRHxjSrbhUXHTkr31qCafU
Kevin51
in
Cure Parkinson's
2 years ago
Can you use red yeast rice with carbadopa/levodopa to lower cholesterol? Is it safe to use?
Trying to lower cholesterol. Is it safe to use red yeast rice with Carbidopa levodopa? I don't want to take statins. Thanks for your help!
Trying to lower cholesterol. Is it safe to use red yeast rice with Carbidopa levodopa? I don't want to take statins. Thanks for your help!
Smittybear7
in
Cure Parkinson's
2 years ago
levodopa and sleep
I've been struggling with sleep for a couple of years (actually a couple of decades, but it got worse a couple of years ago. after going down the medication hole (with no lasting help) I remembered that a couple of folks had mentioned here that reducing bedtime levodopa helped with sleep. I cut back
I've been struggling with sleep for a couple of years (actually a couple of decades, but it got worse a couple of years ago. after going down the medication hole (with no lasting help) I remembered that a couple of folks had mentioned here that reducing bedtime levodopa helped with sleep. I cut back
rebtar
in
Cure Parkinson's
2 years ago
Effect of Doxycycline in Levodopa Treated Parkinson's Disease Patients
New clinical trial registered in Bangladesh: Researchers will be evaluating doxycycline (50mg 2x daily or placebo) in 60 individuals with levodopa-treated Parkinsons; 8 weeks treatment randomised, double blinded; UPDRS & C-reactive protein are endpoints https://clinicaltrials.gov/ct2/show/NCT05492019
New clinical trial registered in Bangladesh: Researchers will be evaluating doxycycline (50mg 2x daily or placebo) in 60 individuals with levodopa-treated Parkinsons; 8 weeks treatment randomised, double blinded; UPDRS & C-reactive protein are endpoints https://clinicaltrials.gov/ct2/show/NCT05492019
Farooqji
in
Cure Parkinson's
2 years ago
Mucuna Supplements’ Levodopa Levels are Not Consistent (not surprised)
https://medicalxpress.com/news/2022-08-otc-supplements-high-levodopa-paranoia.html
https://medicalxpress.com/news/2022-08-otc-supplements-high-levodopa-paranoia.html
Juliegrace
in
Cure Parkinson's
2 years ago
Levodopa Overmedication – Common, Unrecognized, Devastating
Dystonia – muscle tightness – is a common symptom of Parkinson's. It can also be a symptom of levodopa overmedication. The only study I could find of this phenomenon was done in 1999 and received very little notice from the medical community: http://bbs.neuro.or.kr/space/journal/1999/9904010.pdf As
Dystonia – muscle tightness – is a common symptom of Parkinson's. It can also be a symptom of levodopa overmedication. The only study I could find of this phenomenon was done in 1999 and received very little notice from the medical community: http://bbs.neuro.or.kr/space/journal/1999/9904010.pdf As
park_bear
in
Cure Parkinson's
2 years ago
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