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More Evidence Linking ADT for PCa to Adverse Neurocognitive Effects -Meta-analysis shows increased risk of dementia, Parkinson's, depression
[i]As if we needed more reasons to dislike or avoid ADT, here is additional evidence of negative neurocognitive effects. This MedPage Today article will expecially be of special interest to those of us well into our "Golden Years" and on or considering ADT. [/i]
More Evidence Linking ADT for Prostate
[i]As if we needed more reasons to dislike or avoid ADT, here is additional evidence of negative neurocognitive effects. This MedPage Today article will expecially be of special interest to those of us well into our "Golden Years" and on or considering ADT. [/i]
More Evidence Linking ADT for Prostate
cujoe
in
Fight Prostate Cancer
6 months ago
Almost ready for phase 1: JHU083 (or JHU-083) a selective glutamine metabolism blocker
"The drug, JHU083, is a type of molecule called a prodrug that cells inside the body convert into an active drug. Specifically, JHU083 can only be turned into its active, glutamine-blocking form inside the tumor, preventing it from causing harmful side effects elsewhere in the body. " We all know that
"The drug, JHU083, is a type of molecule called a prodrug that cells inside the body convert into an active drug. Specifically, JHU083 can only be turned into its active, glutamine-blocking form inside the tumor, preventing it from causing harmful side effects elsewhere in the body. " We all know that
Maxone73
in
Advanced Prostate Cancer
1 month ago
Struggling with disimpaction regime
Hello, really hoping someone has some advice as I’m at the end of my tether! My son is 5, he has struggled with constipation since he was 6 months old. He went onto Movicol (just x1 sachet a day) which was working fine to keep his stools soft and passable however when he began potty training at 3y/o
Hello, really hoping someone has some advice as I’m at the end of my tether! My son is 5, he has struggled with constipation since he was 6 months old. He went onto Movicol (just x1 sachet a day) which was working fine to keep his stools soft and passable however when he began potty training at 3y/o
Lem14
in
ERIC
1 month ago
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Vitamin B12 Sublingual - Why do I feel sleepy?
Hello Everyone Just took a tablet of Vitamin B12 Sublingual today morning just after breakfast and felt v sleepy and took a short nap after noon. Is this expected? Has anyone experienced this? This is the brand that I bought: https://www.cytoplan.co.uk/vitamin-b12-sublingual-as-methylcobalamin-adenosylcobalamin
Hello Everyone Just took a tablet of Vitamin B12 Sublingual today morning just after breakfast and felt v sleepy and took a short nap after noon. Is this expected? Has anyone experienced this? This is the brand that I bought: https://www.cytoplan.co.uk/vitamin-b12-sublingual-as-methylcobalamin-adenosylcobalamin
BookLover2020
in
Thyroid UK
1 month ago
Newly diagnosed. Looking for advice
Good morning. I've sadly recently been diagnosed with ulcerative colitis. I was suffering 5 years ago with calprotectin score 450 and had a urgent colonoscopy that found polyps and piles which were removed biopsied/ banded. Continued to have on off blood in stools for a few years each time I was blaming
Good morning. I've sadly recently been diagnosed with ulcerative colitis. I was suffering 5 years ago with calprotectin score 450 and had a urgent colonoscopy that found polyps and piles which were removed biopsied/ banded. Continued to have on off blood in stools for a few years each time I was blaming
Raerae2781
in
Crohn's and Colitis Support
1 month ago
Please Help Me.
Hello all! I'm a 29 year old guy from the UK. I've had diarrearh for nearly 6 weeks. I have severe bloating. I was admitted to Hospital last week, they've asked me to do a Bowel cancer sample test (which I've done) During the blood tests they've found my Liver Enzymes are elevated. They've ordered
Hello all! I'm a 29 year old guy from the UK. I've had diarrearh for nearly 6 weeks. I have severe bloating. I was admitted to Hospital last week, they've asked me to do a Bowel cancer sample test (which I've done) During the blood tests they've found my Liver Enzymes are elevated. They've ordered
Lmm4
in
British Liver Trust
1 month ago
PLUVICTO.................
Getting ready for my 5th infusion of Pluvicto. The side effects usually ground me for two to three weeks, and i always say that i am through, and can't stand anymore. When i started, my PSA was 42 + a point. It went down to 22+ a point and as of today it is 10.6. I have been boarding my dog,
Getting ready for my 5th infusion of Pluvicto. The side effects usually ground me for two to three weeks, and i always say that i am through, and can't stand anymore. When i started, my PSA was 42 + a point. It went down to 22+ a point and as of today it is 10.6. I have been boarding my dog,
PianoMan3048
in
Men's Health Forum
6 months ago
Peripheral neuropathy and neurology's response
Hi. I've posted a couple of times recently so I'll start with a precise and then my ask! I was diagnosed with Vitamin B12 deficiency in 2015 - I wasn't tested for PA. I have self-injected for 4 years (hydroxocobalamin) - and got my life back by injecting every other day (sometimes increasing to daily
Hi. I've posted a couple of times recently so I'll start with a precise and then my ask! I was diagnosed with Vitamin B12 deficiency in 2015 - I wasn't tested for PA. I have self-injected for 4 years (hydroxocobalamin) - and got my life back by injecting every other day (sometimes increasing to daily
LizWilsonpa
in
Pernicious Anaemia Society
1 month ago
Bloating for 2 months
Hi, does anyone suffer with bloating but all the time? For the last couple of months my stomach has felt bloated most days and more recently I have had a gurgling stomach, mucus in my poo, lower back pain, urgency and acid reflux. I am currently having bloods, stool samples etc to rule out other things
Hi, does anyone suffer with bloating but all the time? For the last couple of months my stomach has felt bloated most days and more recently I have had a gurgling stomach, mucus in my poo, lower back pain, urgency and acid reflux. I am currently having bloods, stool samples etc to rule out other things
Starshine83
in
IBS Network
1 month ago
Lloyd Austin
"Washington CNN Defense Secretary Lloyd Austin is being treated for prostate cancer and suffered complications that led to him being taken to hospital on New Year’s Day where he is still being treated, according to a statement Tuesday from Walter Reed National Military Medical Center. The statement
"Washington CNN Defense Secretary Lloyd Austin is being treated for prostate cancer and suffered complications that led to him being taken to hospital on New Year’s Day where he is still being treated, according to a statement Tuesday from Walter Reed National Military Medical Center. The statement
Justfor_
in
Fight Prostate Cancer
6 months ago
Functional Gerd/Heartburn
Good day everyone, has anyone ever researched this topic ? I was diagnosed with AIG few months back, started EOD injections and recently developed what feels like heartburn, which I have never had before. The pain is usually in bottom chest area and is accompanied with flatulence and burping. I read
Good day everyone, has anyone ever researched this topic ? I was diagnosed with AIG few months back, started EOD injections and recently developed what feels like heartburn, which I have never had before. The pain is usually in bottom chest area and is accompanied with flatulence and burping. I read
Canadian77
in
Pernicious Anaemia Society
1 month ago
Upper left pain and soreness
Hi …. Does anyone else suffer from upper left quarter / centre pain and discomfort. Side almost feels sore (almost like muscular soreness). Constant belching and flatulence, sometimes loose or constipated. Been going on for 4 months. Had colonoscopy and Abdominal and Pelvic CT scan, all clear but symptoms
Hi …. Does anyone else suffer from upper left quarter / centre pain and discomfort. Side almost feels sore (almost like muscular soreness). Constant belching and flatulence, sometimes loose or constipated. Been going on for 4 months. Had colonoscopy and Abdominal and Pelvic CT scan, all clear but symptoms
Dh19
in
IBS Network
1 month ago
Confused about potential ibs c with overflow diagnosis
So after having a constant list of other symptoms unrelated to bowels i have finally spoke to a gastro who is assuming i have ibs c with overflow. I am on the waiting list for a colonoscopy so this potential diagnosis has been made on a 5 min phone call not an in person appointment. My confusion comes
So after having a constant list of other symptoms unrelated to bowels i have finally spoke to a gastro who is assuming i have ibs c with overflow. I am on the waiting list for a colonoscopy so this potential diagnosis has been made on a 5 min phone call not an in person appointment. My confusion comes
Confused1806
in
IBS Network
1 month ago
bowel blockage
Had bowel resection 6 years ago . Iliostomy bag and then successful reversal . Had an appendectomy about a year later, because my appendix were stuck to my ileostomy scar internally. I had pain and went to the hospital, but my surgery wasn’t emergency. I was scheduled about two weeks later for the appendectomy
Had bowel resection 6 years ago . Iliostomy bag and then successful reversal . Had an appendectomy about a year later, because my appendix were stuck to my ileostomy scar internally. I had pain and went to the hospital, but my surgery wasn’t emergency. I was scheduled about two weeks later for the appendectomy
Gardeningbuff
in
Bowel Disease Support
1 month ago
History of continued low and fluctuating iron levels - advice?
hi folks. Just had my latest bloods back from helpful GP (he’s actually happy for me to sort my thyroid with Roseway! TSH barely exists) My iron is pretty abysmal tho .. Last time i had my transferrin saturation index done it was 40% so bang on mid way. January I think it was. It’s now dropped to19%
hi folks. Just had my latest bloods back from helpful GP (he’s actually happy for me to sort my thyroid with Roseway! TSH barely exists) My iron is pretty abysmal tho .. Last time i had my transferrin saturation index done it was 40% so bang on mid way. January I think it was. It’s now dropped to19%
Starseed56
in
Thyroid UK
1 month ago
pelvic pain
Has anyone tried MRI Defecography tests for rectum and anal pain? It’s a first suggested to me. Don’t know if this may help diagnose this pain.
Has anyone tried MRI Defecography tests for rectum and anal pain? It’s a first suggested to me. Don’t know if this may help diagnose this pain.
Sissy8-1-2019
in
Pelvic Pain Support Network
1 month ago
Are Lymph nodes a filter?
Do lymph nodes simply act as a temporary filter to prevent cancer from spreading too far? I was curious about this because I have 4th stage prostate cancer, and my Lymph had swelled to the size of a golfball. When I took the ADT, my PSA went from 1000, down to 6, and all evidence of cancer disappeared
Do lymph nodes simply act as a temporary filter to prevent cancer from spreading too far? I was curious about this because I have 4th stage prostate cancer, and my Lymph had swelled to the size of a golfball. When I took the ADT, my PSA went from 1000, down to 6, and all evidence of cancer disappeared
Aldo62
in
Advanced Prostate Cancer
6 months ago
Will Existing Drugs Stop Cancer's Bone Spread? I don't know but it's driving me crazy!
Just because I cannot know which are the two repurposed drugs that seem to have such great results with metastasis. The chief researcher is Neta Erez who has great reputation in research about bone metastasis. I am inclined to think about Ivermectin as one of the possible components of the cocktail,
Just because I cannot know which are the two repurposed drugs that seem to have such great results with metastasis. The chief researcher is Neta Erez who has great reputation in research about bone metastasis. I am inclined to think about Ivermectin as one of the possible components of the cocktail,
Maxone73
in
Fight Prostate Cancer
1 month ago
retroperitoneal mass
Hi,I have been diagnosed with deep infiltrative endometriosis and adenomyosis. On my MRI is also shows a sub rectal mass and a 8cm retroperitoneal mass. My ca125 blood tests have been between 72-94 but that could be caused by the endometriosis. I had a biopsy of the mass on thursday and anxiously waiting
Hi,I have been diagnosed with deep infiltrative endometriosis and adenomyosis. On my MRI is also shows a sub rectal mass and a 8cm retroperitoneal mass. My ca125 blood tests have been between 72-94 but that could be caused by the endometriosis. I had a biopsy of the mass on thursday and anxiously waiting
Eclair88
in
Endometriosis UK
1 month ago
So much stool
saw colorectal 3 days ago was told had so many hard stool pebbles and piles and anal tags just given again 15 suppositories And told needed to be admitted but wasn’t allowed this has gone on since last Oct Pain some days unbearable I take Lactulose Fibogel ducosate what can I do Also told me
saw colorectal 3 days ago was told had so many hard stool pebbles and piles and anal tags just given again 15 suppositories And told needed to be admitted but wasn’t allowed this has gone on since last Oct Pain some days unbearable I take Lactulose Fibogel ducosate what can I do Also told me
Perrie46
in
Bowel Disease Support
1 month ago
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