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Trying to make sense of things
Can anyone explain why some people have Gleason 8 PC, high PSA and have metastatic disease, yet some with Gleason 9 and 10 have low-ish PSA (as far as PC goes) and no obvious metastatic disease (confirmed by PSMA)? I am trying to understand this damn disease and sometimes there doesn’t seem to be any
Can anyone explain why some people have Gleason 8 PC, high PSA and have metastatic disease, yet some with Gleason 9 and 10 have low-ish PSA (as far as PC goes) and no obvious metastatic disease (confirmed by PSMA)? I am trying to understand this damn disease and sometimes there doesn’t seem to be any
EvFC
in
Advanced Prostate Cancer
2 months ago
Olaparib time to lower PSA
Hello all, Anyone know how long it take for Olaparib ro lower PSA? All I can find is that it takes 90 days to start working. Thanks
Hello all, Anyone know how long it take for Olaparib ro lower PSA? All I can find is that it takes 90 days to start working. Thanks
Seebs9
in
Advanced Prostate Cancer
2 months ago
Rigidity Dominant Parkinson's Disease (Rigid PD)
Dear All, After 9 years of Parkinson's Disease diagnosis, and 4 years of HU, and trying supplements of every 'improvement' story, I think I have it all wrong. I have Rigid PD, no tremors. Cogwheel rigidity and extreme speech impairment. Now after 9 years I have some trembling in the knees if unmedicated
Dear All, After 9 years of Parkinson's Disease diagnosis, and 4 years of HU, and trying supplements of every 'improvement' story, I think I have it all wrong. I have Rigid PD, no tremors. Cogwheel rigidity and extreme speech impairment. Now after 9 years I have some trembling in the knees if unmedicated
JayPwP
in
Cure Parkinson's
2 months ago
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Is pluvicto helping?
I started pluvicto on Jan 24, 2024. I’m on zoladex quarterly as well. I currently feel good compared to when i began pluvicto. My labwork are all normal, no abnormalities. My last scans show reduced mets in lymph nodes but still in bones and no progression. Would you say things are looking good with
I started pluvicto on Jan 24, 2024. I’m on zoladex quarterly as well. I currently feel good compared to when i began pluvicto. My labwork are all normal, no abnormalities. My last scans show reduced mets in lymph nodes but still in bones and no progression. Would you say things are looking good with
setho
in
Advanced Prostate Cancer
2 months ago
My PCa history
After rising PSA from 6.92 in March 2012 to 9.98 in April 2013 Uro performed Prostate Biopsy in April 2013. 12 samples were taken: worst sample 4+3 (30% involvement) and four samples 3+4 (5% involvement). Scheduled for robotic prostatectomy, but before it Uro gave me four shots of Fermagon. Uro
After rising PSA from 6.92 in March 2012 to 9.98 in April 2013 Uro performed Prostate Biopsy in April 2013. 12 samples were taken: worst sample 4+3 (30% involvement) and four samples 3+4 (5% involvement). Scheduled for robotic prostatectomy, but before it Uro gave me four shots of Fermagon. Uro
Maxi54
in
Advanced Prostate Cancer
2 months ago
Just diagnosed with autoimmune atrophic gastritis with intestinal metaplasia
I assume this is the root cause of my pernicious anemia? I have an appointment this week to discuss with GI, but want to go into the appointment educated. Does anyone else have this? Any treatment for this? I’m already on EOD (for last two weeks) B12 shots and multivitamins. Thanks in advance for your
I assume this is the root cause of my pernicious anemia? I have an appointment this week to discuss with GI, but want to go into the appointment educated. Does anyone else have this? Any treatment for this? I’m already on EOD (for last two weeks) B12 shots and multivitamins. Thanks in advance for your
ReallyWondering
in
Pernicious Anaemia Society
6 months ago
Kidney gfr
So last time my mam was told her kidneys were at 6% and yesterday while we were at a&e she's been told her kidneys are at 30% is this normal my mam has been on dialysis for 10 months.
So last time my mam was told her kidneys were at 6% and yesterday while we were at a&e she's been told her kidneys are at 30% is this normal my mam has been on dialysis for 10 months.
Jk2023
in
Kidney Dialysis
2 months ago
AUA 2024: mCRPC: Key Updates in Radioligand Therapy, PSMA Sensitive Disease
(UroToday.com) The 2024 American Urological Association (AUA) Annual Meeting held in San Antonio, TX was host to the International Prostate Forum. Dr. Jeremie Calais presented key updates in radioligand therapy for patients with PSMA-sensitive disease. The field of prostate cancer theranostics has
(UroToday.com) The 2024 American Urological Association (AUA) Annual Meeting held in San Antonio, TX was host to the International Prostate Forum. Dr. Jeremie Calais presented key updates in radioligand therapy for patients with PSMA-sensitive disease. The field of prostate cancer theranostics has
God_Loves_Me
in
Advanced Prostate Cancer
2 months ago
test results explained
just had these test results from monitor my health and wondering if I should be on some sort of medication, have had symptoms of underactive thyroid for several years but GP tests always come back normal however they don’t test for antibodies , any help appreciated
just had these test results from monitor my health and wondering if I should be on some sort of medication, have had symptoms of underactive thyroid for several years but GP tests always come back normal however they don’t test for antibodies , any help appreciated
Valerina
in
Thyroid UK
6 months ago
Info re another Auto Immune malady. Parkinson's
This info from the Michael J. Fox institute might be of interest to other followers of this site. The topic is dealing with the pain associated with Parkinson's disease (PD). Perhaps there is some advice relevant to PMR- from which I have suffered for more than a decade. In my circle of long standing
This info from the Michael J. Fox institute might be of interest to other followers of this site. The topic is dealing with the pain associated with Parkinson's disease (PD). Perhaps there is some advice relevant to PMR- from which I have suffered for more than a decade. In my circle of long standing
Canuk
in
PMRGCAuk
2 months ago
What is a Healthy, low sugar shake or supplement to gain weight with prostate cancer spread to lymph nodes?
Husband has advanced prostate cancer mets to neck, chest, back, pelvis, femur. PSA is doubling rapidly. Currently on Zytiga, Lupron, Steroid, and Lyparza. 😞 Diagnosed in 2020 with tumor base of tongue (doctors said it was not related to PC) and aggressive prostate cancer at same time. Today, four years
Husband has advanced prostate cancer mets to neck, chest, back, pelvis, femur. PSA is doubling rapidly. Currently on Zytiga, Lupron, Steroid, and Lyparza. 😞 Diagnosed in 2020 with tumor base of tongue (doctors said it was not related to PC) and aggressive prostate cancer at same time. Today, four years
Bamagrad
in
Advanced Prostate Cancer
2 months ago
PMR and Pfizer Covid Vaccine
Within 5 days of my husband and I receiving the first Pfizer Covid jab, he started getting pains in his legs and shoulders. He took paracetamol & used Bio Freeze, similar to deep heat. He got progressively worse, a GP diagnosed Frozen Shoulder over the phone, prescribed Co-Codamol & Naproxen. Within
Within 5 days of my husband and I receiving the first Pfizer Covid jab, he started getting pains in his legs and shoulders. He took paracetamol & used Bio Freeze, similar to deep heat. He got progressively worse, a GP diagnosed Frozen Shoulder over the phone, prescribed Co-Codamol & Naproxen. Within
heartsonfire
in
PMRGCAuk
7 months ago
Various questions, sorry 🥹
I hope you’re all doing as well as you can be 💜 this is going to be a long post so firstly I just want to apologise but any advice would be massively appreciated. I have also, attached a photo of my kitten to put a smile on all your faces, as she does mine on a daily basis 🥹 (scroll to the bottom for
I hope you’re all doing as well as you can be 💜 this is going to be a long post so firstly I just want to apologise but any advice would be massively appreciated. I have also, attached a photo of my kitten to put a smile on all your faces, as she does mine on a daily basis 🥹 (scroll to the bottom for
JLAR01
in
LUPUS UK
6 months ago
Hep B and mild sign of fatty liver.
I have been on entecavir for 3 years now for long term hap b. And my last ultrasound at febuary I also have mild signs of fatty liver. I'm worried and like get some advice here my ultrasound I have no signs of liver chirrosis. Thank Pauline
I have been on entecavir for 3 years now for long term hap b. And my last ultrasound at febuary I also have mild signs of fatty liver. I'm worried and like get some advice here my ultrasound I have no signs of liver chirrosis. Thank Pauline
Paulini
in
British Liver Trust
2 months ago
Anemia on Abiraterone + Prednisone + Lupron
Since November 2023 I have been taking Abiraterone + Prednosone for castrate resistant metastatic prostate cancer. In November my PSA was 0.8. In the first three months it went down to 0.26. Yesterday, my PSA was 0.16. But my hemoglobin and hematocrit became low at 11.6 and 36% respectively.
Since November 2023 I have been taking Abiraterone + Prednosone for castrate resistant metastatic prostate cancer. In November my PSA was 0.8. In the first three months it went down to 0.26. Yesterday, my PSA was 0.16. But my hemoglobin and hematocrit became low at 11.6 and 36% respectively.
dac500
in
Advanced Prostate Cancer
2 months ago
Input on Timing of Initial ADT after RP/SRT Failed
After surgery and salvage radiation therapy (SRT) have failed, it appears I'm headed for androgen deprivation therapy. Like many things in the world of prostate cancer, the recommendations as to when to start ADT seem to be all over the place, so I'm seeking any insights folks may have based on your
After surgery and salvage radiation therapy (SRT) have failed, it appears I'm headed for androgen deprivation therapy. Like many things in the world of prostate cancer, the recommendations as to when to start ADT seem to be all over the place, so I'm seeking any insights folks may have based on your
dans_journey
in
Advanced Prostate Cancer
2 months ago
Help!
I have been unwell for about 8 months now with all the symptoms of Addison's Disease(which I only new about recently) I had blood cortisol tests done 1 week apart at 9am.1. 128 nmol/L 2. 250 nmol/L My gp says this doesn't warrant further investigation despite all of my symptoms. Most other tests were
I have been unwell for about 8 months now with all the symptoms of Addison's Disease(which I only new about recently) I had blood cortisol tests done 1 week apart at 9am.1. 128 nmol/L 2. 250 nmol/L My gp says this doesn't warrant further investigation despite all of my symptoms. Most other tests were
Adoptdontshop
in
Thyroid UK
2 months ago
Arthritis
Does everyone who has this condition end up getting arthritis or some form of it?
Does everyone who has this condition end up getting arthritis or some form of it?
Caulkhead63
in
PMRGCAuk
6 months ago
test results
I have just had my yearly thyroid test results: Serum TSH Level 3.12mu/L (0.35- 494) Serum free T4 Level 13.6pmol/L (9.0- 19ul) FT3 3.7 pmol/L (2.4-6.0) I also had a cholesterol test and it’s 8 gone up in 2 months from 7.8. Despite a healthy diet and drinking a cholesterol lowering drink every
I have just had my yearly thyroid test results: Serum TSH Level 3.12mu/L (0.35- 494) Serum free T4 Level 13.6pmol/L (9.0- 19ul) FT3 3.7 pmol/L (2.4-6.0) I also had a cholesterol test and it’s 8 gone up in 2 months from 7.8. Despite a healthy diet and drinking a cholesterol lowering drink every
Hidden
in
Thyroid UK
6 months ago
Hemosiderin staining?
Hi, Has anyone else experienced this? I’ve woken up today with rust like staining, mainly on my left hand with a little on my right. No logical cause from anything I’ve touched. Googling seems to suggest it is hemosiderin staining, though they are mainly US sites. This could make sense as I still
Hi, Has anyone else experienced this? I’ve woken up today with rust like staining, mainly on my left hand with a little on my right. No logical cause from anything I’ve touched. Googling seems to suggest it is hemosiderin staining, though they are mainly US sites. This could make sense as I still
Allotmental
in
Vasculitis UK
3 months ago
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