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Glycerol phenylbutyrate
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First experiences with Pegasys for Polythycemia Vera
I've had PV for about 10 years, managing it with phlebotomies and aspirin but I've been eager to try Pegasys and avoid HU. HU is a really old, pharmacokinetically poorly characterised drug which causes DNA damage (https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5126785/, https://www.researchgate.net
I've had PV for about 10 years, managing it with phlebotomies and aspirin but I've been eager to try Pegasys and avoid HU. HU is a really old, pharmacokinetically poorly characterised drug which causes DNA damage (https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5126785/, https://www.researchgate.net
pnArt
in
MPN Voice
5 years ago
Angina
Hi Following on from a previous post regarding my broken nose following a blackout(coughing fit) I have now seen heart consultant after a few months of delay by hospital. I was sent for ECG stress test and Echocardiogram. At the stress test after 6 minutes I had some readings which indicated a problem
Hi Following on from a previous post regarding my broken nose following a blackout(coughing fit) I have now seen heart consultant after a few months of delay by hospital. I was sent for ECG stress test and Echocardiogram. At the stress test after 6 minutes I had some readings which indicated a problem
Leythersrus1
in
British Heart Foundation
5 years ago
Meds gastritis and heart nerves 😩
Hello all, hope all are well! Back at hospital yesterday 8weeks after STEMI with odd sort of chest sharp pain that lasts seconds but horrendous indigestion like pains. ECG showing nothing other than historic STEMI and bloods troponin at 8! Docs think I maybe reacting to prasugrel and it’s causing gastritis
Hello all, hope all are well! Back at hospital yesterday 8weeks after STEMI with odd sort of chest sharp pain that lasts seconds but horrendous indigestion like pains. ECG showing nothing other than historic STEMI and bloods troponin at 8! Docs think I maybe reacting to prasugrel and it’s causing gastritis
DaveyG71
in
British Heart Foundation
5 years ago
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Palpitations, ectopic and fibrillations
Hi all, I am 54 years old and I had a HA 11 weeks ago. Stent fitted and put on usual meds, which included ticagrelor. Shortly after discharge I started to get palpitations, ectopic beats and fibrillations. I now get them on a daily basis and I can have up to 15 plus palpitations during a day. I am
Hi all, I am 54 years old and I had a HA 11 weeks ago. Stent fitted and put on usual meds, which included ticagrelor. Shortly after discharge I started to get palpitations, ectopic beats and fibrillations. I now get them on a daily basis and I can have up to 15 plus palpitations during a day. I am
Russ65
in
British Heart Foundation
5 years ago
Couple of questions please :)
Firstly, does anyone know if any of the heart meds cause ringing in the ears? I’ve just started an extra one this week, Trangina XL, kind of a slow release constant GTN, am wondering if it’s that? Also, does anyone have experience of ‘complicated angioplasty’ I have 2 narrowings on the LAD, one which
Firstly, does anyone know if any of the heart meds cause ringing in the ears? I’ve just started an extra one this week, Trangina XL, kind of a slow release constant GTN, am wondering if it’s that? Also, does anyone have experience of ‘complicated angioplasty’ I have 2 narrowings on the LAD, one which
Sillyfroggy
in
British Heart Foundation
5 years ago
New running shoes
So I bought some new running shoes (brooks glycerin 16. About 5-10 into using them I’m getting pain on my left foot only on the Outside for 10-15 mins then it seems to go. Is this just a case of breaking them in or is it A foot issue? I’ve never had it Before with other trainers but these are my first
So I bought some new running shoes (brooks glycerin 16. About 5-10 into using them I’m getting pain on my left foot only on the Outside for 10-15 mins then it seems to go. Is this just a case of breaking them in or is it A foot issue? I’ve never had it Before with other trainers but these are my first
Jmcgrath251188
in
Couch to 5K
5 years ago
Echo showed strong heartbeat, pericardial scarring and fluid, and aortic valve scarring
Backstory: I'm a 'split-personality' lady Briton - born in the USA to British expat parents who divorced shortly after I was born - Mum returned to GB, Dad brought myself, my older brother and sister up in the US (Desert South-West, family cattle ranch). I spent my childhood half-half, back and forth
Backstory: I'm a 'split-personality' lady Briton - born in the USA to British expat parents who divorced shortly after I was born - Mum returned to GB, Dad brought myself, my older brother and sister up in the US (Desert South-West, family cattle ranch). I spent my childhood half-half, back and forth
Sunnie2day
in
British Heart Foundation
5 years ago
Not sure what’s wrong
Hi all, I’m 42 female, normally healthy and fit. I had what seemed like a heart attack 4 weeks ago, I was not long awake been in shower and the chest pain hit and radiating up to my jaw, I went into a&e by ambulance they did ecg’s and bloods and chest x Ray all normal so they discharged me. Then 2 nights
Hi all, I’m 42 female, normally healthy and fit. I had what seemed like a heart attack 4 weeks ago, I was not long awake been in shower and the chest pain hit and radiating up to my jaw, I went into a&e by ambulance they did ecg’s and bloods and chest x Ray all normal so they discharged me. Then 2 nights
Madparent007
in
British Heart Foundation
5 years ago
Hello
Hello I’m a heart attack survivor from May 2019. I woke up at 430 am feeling as though I had slept on my arm and felt unwell. Nothing major just felt yuk. I tossed and turned not getting comfortable and got up to go to the bathroom and was sick. (Thought it was a dodgy egg from dinner) couldn’t sleep
Hello I’m a heart attack survivor from May 2019. I woke up at 430 am feeling as though I had slept on my arm and felt unwell. Nothing major just felt yuk. I tossed and turned not getting comfortable and got up to go to the bathroom and was sick. (Thought it was a dodgy egg from dinner) couldn’t sleep
Brokenheart19
in
British Heart Foundation
5 years ago
Heart attack 3 weeks ago and feeling confused. Need advice.
Hi everyone, I'm a 47 year old woman who had a heart attack 3 weeks ago. I was a 40 plus a day smoker, under extreme stress and overweight. I started to feel unwell in the evening so went to bed. I woke up at 2 minutes to midnight feeling dehydrated and rotten. Drinking water really stung my heart. Anyway
Hi everyone, I'm a 47 year old woman who had a heart attack 3 weeks ago. I was a 40 plus a day smoker, under extreme stress and overweight. I started to feel unwell in the evening so went to bed. I woke up at 2 minutes to midnight feeling dehydrated and rotten. Drinking water really stung my heart. Anyway
Kirsten47
in
British Heart Foundation
5 years ago
GTN - 1st use, stopped angina pain but felt unwell for hours after - Normal?
I was given NitroLingual 400mg spray with a set of verbal instructions from the GP in late April. Got it home, read the package insert leaflet over three times then pinned it to the fridge. Carry it with me everywhere but didn't need it (Bisoprolol 1.25mg seems to be doing a very good job, and I'm tolerating
I was given NitroLingual 400mg spray with a set of verbal instructions from the GP in late April. Got it home, read the package insert leaflet over three times then pinned it to the fridge. Carry it with me everywhere but didn't need it (Bisoprolol 1.25mg seems to be doing a very good job, and I'm tolerating
Sunnie2day
in
British Heart Foundation
5 years ago
Micralax
I have variable IBS C and D but am mainly having problems with constipation at the moment. I do go to the loo several times a day but have to strain and always feel there is something left behind. Glycerin suppositories help but aren`t comfortable to use so I am trying Micralax mini enemas instead.
I have variable IBS C and D but am mainly having problems with constipation at the moment. I do go to the loo several times a day but have to strain and always feel there is something left behind. Glycerin suppositories help but aren`t comfortable to use so I am trying Micralax mini enemas instead.
janke
in
IBS Network
5 years ago
Stent fitted 2 days ago specific chest pains
I had a stent fitted after having my LAD 70% restricted, op went well and Kings in London were excellent. on my first day home I slept great and had a day of part rest and part active to slowly get back into things. I tried to put teh anxiety to one side with some non specific chest discomforts not pains
I had a stent fitted after having my LAD 70% restricted, op went well and Kings in London were excellent. on my first day home I slept great and had a day of part rest and part active to slowly get back into things. I tried to put teh anxiety to one side with some non specific chest discomforts not pains
Phil_London
in
British Heart Foundation
5 years ago
Specific Chest Pains 2 days after a Stent was fitted
I had a stent fitted after having my LAD 70% restricted, op went well and Kings in London were excellent. on my first day home I slept great and had a day of part rest and part active to slowly get back into things. I tried to put teh anxiety to one side with some non specific chest discomforts not pains
I had a stent fitted after having my LAD 70% restricted, op went well and Kings in London were excellent. on my first day home I slept great and had a day of part rest and part active to slowly get back into things. I tried to put teh anxiety to one side with some non specific chest discomforts not pains
Phil_London
in
British Heart Foundation
5 years ago
HAPPY DAYS, and rainbows
It's been 2 month's (knock on wood) since I had a really server bowel pain from my ibs c. I'm taking a multivitamin without iron, iron will just make things worse trust me. But this multivitamin has magnesium in it which seems like that top of polyethylene glycol and the low fod map diet helps with
It's been 2 month's (knock on wood) since I had a really server bowel pain from my ibs c. I'm taking a multivitamin without iron, iron will just make things worse trust me. But this multivitamin has magnesium in it which seems like that top of polyethylene glycol and the low fod map diet helps with
Alphanes
in
IBS Network
5 years ago
Back in hospital after just 4 days at home after double bypass !!!!!
WHAT IS GOING ON Discharged 17th may medication stopped Nitrolingual spray Mononitate pills Renaxa something ? Amlodopine I thought I was doing well . Gentle walks around the house. Can manage the stairs . Showers are slow but fine . Last couple of days noticed on walking up stairs I was feeling
WHAT IS GOING ON Discharged 17th may medication stopped Nitrolingual spray Mononitate pills Renaxa something ? Amlodopine I thought I was doing well . Gentle walks around the house. Can manage the stairs . Showers are slow but fine . Last couple of days noticed on walking up stairs I was feeling
jelliebean9
in
British Heart Foundation
5 years ago
BMs and shaky legs!
I`m having to use glycerin suppositories at the moment to combat constipation - they work well but after a BM (which can be quite powerful!) my legs are wobbly for an hour or 2 after. Does anyone else find this. When I am going through a diarrhoea phase I also feel wobbly each time I go to the loo.
I`m having to use glycerin suppositories at the moment to combat constipation - they work well but after a BM (which can be quite powerful!) my legs are wobbly for an hour or 2 after. Does anyone else find this. When I am going through a diarrhoea phase I also feel wobbly each time I go to the loo.
janke
in
IBS Network
5 years ago
Microvascular disease
I have had 2 stents fitted and when things didn't improve I was given a stress MRI test and the results are I have microvascular disease. I am on lots of medication but still have periods when i get chest pain, fatigue and breathlessness. The GTN spray does little to help and my GP says i should go to
I have had 2 stents fitted and when things didn't improve I was given a stress MRI test and the results are I have microvascular disease. I am on lots of medication but still have periods when i get chest pain, fatigue and breathlessness. The GTN spray does little to help and my GP says i should go to
kr29
in
British Heart Foundation
5 years ago
Anyone tried Dulcolax suppositories for constipation?
I have used glycerin suppositories to get things moving and they used to work well but now they seem to irritate my rectum so much that I end up having to go to the loo many times all day (even though the suppository seems to get expelled without dissolving much). I see that Dulcolax suppositories
I have used glycerin suppositories to get things moving and they used to work well but now they seem to irritate my rectum so much that I end up having to go to the loo many times all day (even though the suppository seems to get expelled without dissolving much). I see that Dulcolax suppositories
janke
in
IBS Network
5 years ago
Taking together
I have been taking Laxido for the past two days for constipation and this morning used a glycerol suppository. It has worked a bit, but I wanted to know if I can carry on using Laxidol at the same time. I was diagnosed with a hiatus hernia earlier in the week, but think that constipation is the main
I have been taking Laxido for the past two days for constipation and this morning used a glycerol suppository. It has worked a bit, but I wanted to know if I can carry on using Laxidol at the same time. I was diagnosed with a hiatus hernia earlier in the week, but think that constipation is the main
Ripley1
in
IBS Network
5 years ago
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