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FDA Investigating 'Serious Risk' of Malignancy After CAR-T Therapy - Applies to all approved therapies, but benefits still outweigh risks
"Finally, we know that cancer immunotherapy such as checkpoint blockade for solid tumors, which does not rely on
gene
therapy
, can very rarely result in T-cell lymphomas."
"Finally, we know that cancer immunotherapy such as checkpoint blockade for solid tumors, which does not rely on
gene
therapy
, can very rarely result in T-cell lymphomas."
cujoe
in
CLL Support
8 months ago
Not PCa related but sounds like a very promising approach
https://ascopost.com/news/april-2024/advanced-pancreatic-cancer-oncolytic-virus-based-immunostimulatory-
gene
-
therapy
-plus-chemotherapy/
https://ascopost.com/news/april-2024/advanced-pancreatic-cancer-oncolytic-virus-based-immunostimulatory-
gene
-
therapy
-plus-chemotherapy/
Maxone73
in
Advanced Prostate Cancer
3 months ago
BBB opening with focused ultrasound in nonhuman primates and Parkinson’s disease patients:
They can now briefly open select spots in the brain barrier using focused ultrasound and deliver larger particles like
gene
therapy
(in microbubbles). So it would allow for minimally invasive, early treatment of neurological disorders. https://www.science.org/doi/10.1126/sciadv.adf4888?
They can now briefly open select spots in the brain barrier using focused ultrasound and deliver larger particles like
gene
therapy
(in microbubbles). So it would allow for minimally invasive, early treatment of neurological disorders. https://www.science.org/doi/10.1126/sciadv.adf4888?
LeharLover62
in
Cure Parkinson's
1 year ago
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Megan's Update from Mission: Cure
⚠️ Acrigen Update You may be aware of our collaboration with Acrigen Biosciences, a biotech company pioneering the first
gene
therapy
for PRSS1 hereditary pancreatitis. Acrigen demonstrated in the lab that its technology could successfully edit the PRSS1 gene.
⚠️ Acrigen Update You may be aware of our collaboration with Acrigen Biosciences, a biotech company pioneering the first
gene
therapy
for PRSS1 hereditary pancreatitis. Acrigen demonstrated in the lab that its technology could successfully edit the PRSS1 gene.
Skye_MC
Administrator
in
Chronic Pancreatitis Support
10 months ago
Genetic therapy: for solid malignancy hopefully soon
ok, I post them also because they are fellow Italians! But the platform is very promising even if clinical use has been approved only for glioma and glioblastoma at the moment. But there are clinical trials going on for solid tumors, prostate included. https://www.genenta.com/wp-content/uploads/2021
ok, I post them also because they are fellow Italians! But the platform is very promising even if clinical use has been approved only for glioma and glioblastoma at the moment. But there are clinical trials going on for solid tumors, prostate included. https://www.genenta.com/wp-content/uploads/2021
Maxone73
in
Advanced Prostate Cancer
8 months ago
Novel brain penetrant capsids for Parkinson’s disease gene therapy
https://www.youtube.com/watch?v=7f-TBoq0TLo
https://www.youtube.com/watch?v=7f-TBoq0TLo
Hidden
in
Cure Parkinson's
1 year ago
TCR Gene Therapy
the science to cure us is coming https://www.youtube.com/watch?v=LIvVMIcRTew
the science to cure us is coming https://www.youtube.com/watch?v=LIvVMIcRTew
Scout4answers
in
Advanced Prostate Cancer
1 year ago
RGA 314 gene therapy
my doctor asked me to participate in phase 3 RGA 314
gene
therapy
for macular degeneration. I received the reading material to decide if I want to enter the clinical trials.
my doctor asked me to participate in phase 3 RGA 314
gene
therapy
for macular degeneration. I received the reading material to decide if I want to enter the clinical trials.
Slattery
in
Macular Society
1 year ago
clinical trial for gene therapy
my doctor ask me if I would be interested in going into phase 3 clinical trials for macular degeneration
gene
therapy
. Has anyone on this forum been in a clinical trial or what is your opinion?
my doctor ask me if I would be interested in going into phase 3 clinical trials for macular degeneration
gene
therapy
. Has anyone on this forum been in a clinical trial or what is your opinion?
Slattery
in
Macular Society
1 year ago
Anything related with gene therapy??
I wonder.Relating with SCA.
I wonder.Relating with SCA.
Eunseoc
in
Ataxia UK
1 year ago
PV & Gene Editing for Sickle cell anemia
"The F.D.A. approved the first
gene
editing
therapy
ever, for sickle cell disease, a debilitating blood disorder caused by a single mutated gene. This breakthrough offers hope, but also comes with obstacles."
"The F.D.A. approved the first
gene
editing
therapy
ever, for sickle cell disease, a debilitating blood disorder caused by a single mutated gene. This breakthrough offers hope, but also comes with obstacles."
ERei
in
MPN Voice
7 months ago
New gene therapy delivers treatment directly to brain
https://www.pbs.org/newshour/science/new-
gene
-
therapy
-delivers-treatment-directly-to-brain
https://www.pbs.org/newshour/science/new-
gene
-
therapy
-delivers-treatment-directly-to-brain
Farooqji
in
Cure Parkinson's
1 year ago
Involvement Opportunity - PRaCTicAL Research Project (UK)
The British Liver Trust are excited to be working with NHS Lothian, University of Edinburgh, Scottish National Blood Transfusion Services (SNBTS) and Cell and
Gene
Therapy
Catapult as part of a collaboration to create the first ‘Centre for Precision Cell Therapy for the Liver’ in the world.
The British Liver Trust are excited to be working with NHS Lothian, University of Edinburgh, Scottish National Blood Transfusion Services (SNBTS) and Cell and
Gene
Therapy
Catapult as part of a collaboration to create the first ‘Centre for Precision Cell Therapy for the Liver’ in the world.
BritishLiverTrust1
Partner
in
British Liver Trust
1 year ago
A Longevity Mindset is one in which you believe in the ability of science to extend your healthspan, perhaps by ten or twenty years.
Instead, health technologies are accelerating exponentially, continuing to make breakthroughs driven by AI, CRISPR,
gene
therapy
, genome reading and editing—all of which are being focused on expanded healthspan and reversing disease.
Instead, health technologies are accelerating exponentially, continuing to make breakthroughs driven by AI, CRISPR,
gene
therapy
, genome reading and editing—all of which are being focused on expanded healthspan and reversing disease.
Scout4answers
in
Advanced Prostate Cancer
1 year ago
Review of Genetic and Gene Therapy for Parkinson’s Disease
Gene
therapy
is replacing, silencing, or correcting bad DNA with good DNA.
Gene
therapy
is classified under disease-modifying targets and non-disease-modifying targets.
Gene
therapy
is replacing, silencing, or correcting bad DNA with good DNA.
Gene
therapy
is classified under disease-modifying targets and non-disease-modifying targets.
Farooqji
in
Cure Parkinson's
1 year ago
jakafi, PV and retinal tears and detachment
I wonder because a friend told me some cancer drugs /
gene
therapy
drugs can cause this complication. I’m still learning. TY
I wonder because a friend told me some cancer drugs /
gene
therapy
drugs can cause this complication. I’m still learning. TY
DDSmiley63
in
Fight MPN
1 year ago
An article on nutrition and aging.
"For example, the activation of telomerase through a
gene
therapy
strategy has shown therapeutic effects in mouse models of pulmonary fibrosis and aplastic anemia," Blasco added.
"For example, the activation of telomerase through a
gene
therapy
strategy has shown therapeutic effects in mouse models of pulmonary fibrosis and aplastic anemia," Blasco added.
WiscGuy
in
Pernicious Anaemia Society
1 year ago
Biological Therapy - too soon?
Hey All I hope everyone is well. This is my first time posting and I’m really hopeful someone will be able to advise me. I was diagnosed with lupus in Feb after just over 2 years of struggling with symptoms. Initially I was put on prednisolone and hydroxychloroquine until my bloods came back. My bloods
Hey All I hope everyone is well. This is my first time posting and I’m really hopeful someone will be able to advise me. I was diagnosed with lupus in Feb after just over 2 years of struggling with symptoms. Initially I was put on prednisolone and hydroxychloroquine until my bloods came back. My bloods
EeBeee
in
LUPUS UK
4 days ago
Colomycin nebulising
I’m wondering if there is anyone on the above drug. I have been on it now for 10 days and will stay on it for 12 weeks. I have been pretty unwell since March with re occurring psuedamonas. I am on oxygen therapy, I also have bronciectasis and past T.B. also chicken pox pneumonia, I am on steroid therapy
I’m wondering if there is anyone on the above drug. I have been on it now for 10 days and will stay on it for 12 weeks. I have been pretty unwell since March with re occurring psuedamonas. I am on oxygen therapy, I also have bronciectasis and past T.B. also chicken pox pneumonia, I am on steroid therapy
breslin
in
Lung Conditions Community Forum
5 days ago
Median PFS for FCR treated CLL patients with IGHV-M was 14.6 years vs 4.2 years for patients with IGHV-UM. V+O and I+R look to be superior
An update of the long-term follow-up results from the original 300-patient FCR (fludarabine, cyclophosphamide, and rituximab) study initiated at MD Anderson in 1999,
Sustained remissions in CLL after frontline FCR treatment with very-long-term follow-up,
reports ~47% of patients with mutated IGHV
An update of the long-term follow-up results from the original 300-patient FCR (fludarabine, cyclophosphamide, and rituximab) study initiated at MD Anderson in 1999,
Sustained remissions in CLL after frontline FCR treatment with very-long-term follow-up,
reports ~47% of patients with mutated IGHV
AussieNeil
Partner
in
CLL Support
6 days ago
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