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Depression and PA
HelloI started the PA journey in 2021, positive intrinsic factor and gastric parietal cell antibodies. I am hypothyroid. I thought my low mood would resolve after starting injections and at first it seemed to. I was taking B1 and B2, but stopped. I'm not sure that stopping the extra Bs has caused the
HelloI started the PA journey in 2021, positive intrinsic factor and gastric parietal cell antibodies. I am hypothyroid. I thought my low mood would resolve after starting injections and at first it seemed to. I was taking B1 and B2, but stopped. I'm not sure that stopping the extra Bs has caused the
Aumshantii
in
Pernicious Anaemia Society
8 months ago
Intrinsic Factor
It occurred to me that it must be possible to synthesise Intrinsic Factor as a supplement to replace what PA people have lost. Does anyone of a scientific bent have any thoughts on this idea?
It occurred to me that it must be possible to synthesise Intrinsic Factor as a supplement to replace what PA people have lost. Does anyone of a scientific bent have any thoughts on this idea?
Orchard33
in
Pernicious Anaemia Society
8 months ago
A helpful video for me.
https://www.youtube.com/watch?v=q5cyMLt6N7Q This was posted by someone else on this site 6+- months ago and resonated with me. I do not know who the creator is or their credentials. I am more than fine that it is not blessed/authenticated and find it valuable. It differentiates between Intrinsic
https://www.youtube.com/watch?v=q5cyMLt6N7Q This was posted by someone else on this site 6+- months ago and resonated with me. I do not know who the creator is or their credentials. I am more than fine that it is not blessed/authenticated and find it valuable. It differentiates between Intrinsic
WIZARD6787
in
Pernicious Anaemia Society
8 months ago
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help please
Bloods for B12 showed 2,000 high I only got diagnosed because
I
asked for an intrinsic
factor
antibodies gastric parietal cell blood
test
cos
I
was advised to do so not by my dr tho ??
Bloods for B12 showed 2,000 high I only got diagnosed because
I
asked for an intrinsic
factor
antibodies gastric parietal cell blood
test
cos
I
was advised to do so not by my dr tho ??
Windyway
in
Pernicious Anaemia Society
2 months ago
symptoms with treated PA
Hello forum Autoimmune Metaplastic Atrophic Gastritis (AMAG) results in the loss of parietal cells which causes a loss of production of stomach acid and intrinsic factor (IF). The loss of IF results in low B12. My general query is; are there consequences and symptoms connected to a lack of stomach
Hello forum Autoimmune Metaplastic Atrophic Gastritis (AMAG) results in the loss of parietal cells which causes a loss of production of stomach acid and intrinsic factor (IF). The loss of IF results in low B12. My general query is; are there consequences and symptoms connected to a lack of stomach
Laundretta
in
Pernicious Anaemia Society
8 months ago
Intrinsic factor antibody
I've just been back to my GP because
I
had a blood
test
done the other week for intrinsic
factor
antibody.
I
had a result of 3.66 which I thought was positive but my GP just said it's negative ? I had the test done because my vitamins b12 is 211.
I've just been back to my GP because
I
had a blood
test
done the other week for intrinsic
factor
antibody.
I
had a result of 3.66 which I thought was positive but my GP just said it's negative ? I had the test done because my vitamins b12 is 211.
suzybear
in
Pernicious Anaemia Society
7 months ago
Newbie and confused. Functional B12 deficiency?
Anti nuclear antibodies
test
was negative. Intrinsic
factor
antibodies
test
was negative.
I
am aware that false negatives are common. Whenever I have had to have a full blood count at the surgery, my MCV has always been just above the top of the range, as has my lymphocyte count.
Anti nuclear antibodies
test
was negative. Intrinsic
factor
antibodies
test
was negative.
I
am aware that false negatives are common. Whenever I have had to have a full blood count at the surgery, my MCV has always been just above the top of the range, as has my lymphocyte count.
grumpyold
in
Pernicious Anaemia Society
2 months ago
Fundraising
I am very fortunate that I can pop down to P.A. Society Head Quarters to lend a hand. I did this morning. There are 4 volunteers helping the small amount of staff run the organisation . The person there today was inundated when I rocked up. As they are everyday. We could talk for weeks but I said, ‘No
I am very fortunate that I can pop down to P.A. Society Head Quarters to lend a hand. I did this morning. There are 4 volunteers helping the small amount of staff run the organisation . The person there today was inundated when I rocked up. As they are everyday. We could talk for weeks but I said, ‘No
Narwhal10
in
Pernicious Anaemia Society
8 months ago
Found a new way to screw up.
So I am transitioning from swimming due to water temperature to hiking up the side of a mountain at the same time I stopped injecting and went with sublingual. (Only a mile up the mountain.) My body did adjust which is not using up my B12 or reversing out. The only symptom that seemed to get worse and
So I am transitioning from swimming due to water temperature to hiking up the side of a mountain at the same time I stopped injecting and went with sublingual. (Only a mile up the mountain.) My body did adjust which is not using up my B12 or reversing out. The only symptom that seemed to get worse and
WIZARD6787
in
Pernicious Anaemia Society
9 months ago
New papers on PA
There are often new interesting papers on pernicious anemia. I will add them to this thread to keep them all in one place. I'll try to the pick the ones I think are most novel & relevant, but plenty are published every month. To see more, check Google Scholar https://scholar.google.com/scholar?start=
There are often new interesting papers on pernicious anemia. I will add them to this thread to keep them all in one place. I'll try to the pick the ones I think are most novel & relevant, but plenty are published every month. To see more, check Google Scholar https://scholar.google.com/scholar?start=
jade_s
in
Pernicious Anaemia Society
9 months ago
INSECT BITE OVERREACTION Could this trigger lupus or lupus like reaction?
She tested for Lymes Disease and Rheumatoid
factor
. Lymes Disease
test
negative so far.
I
don't recall a tick. But the initial bite looked typical of tick bite. She said inflammatory markers elevated but didnt specify which ones showed this.
She tested for Lymes Disease and Rheumatoid
factor
. Lymes Disease
test
negative so far.
I
don't recall a tick. But the initial bite looked typical of tick bite. She said inflammatory markers elevated but didnt specify which ones showed this.
Mmef1304
in
LUPUS UK
3 months ago
My B12 System
I still go with my neurological system in evaluating success. I am morphing into deciding on treatment for my B12 system which started when I abandoned the concept of adding one supplement at a time without taking into account they all work together and how and why they work together is unknown. A
I still go with my neurological system in evaluating success. I am morphing into deciding on treatment for my B12 system which started when I abandoned the concept of adding one supplement at a time without taking into account they all work together and how and why they work together is unknown. A
WIZARD6787
in
Pernicious Anaemia Society
9 months ago
Seeking reassurance on fatigue and recovery
Hi everyone, I've been managing a rollercoaster of symptoms lately and wanted to see if anyone has experienced something similar.
Onset
: Since December 2022, I had recurring, short episodes of fatigue. About once every month, I would feel it coming on (almost like a cold, but with no sinus/respiratory
Hi everyone, I've been managing a rollercoaster of symptoms lately and wanted to see if anyone has experienced something similar.
Onset
: Since December 2022, I had recurring, short episodes of fatigue. About once every month, I would feel it coming on (almost like a cold, but with no sinus/respiratory
chonkytonk
in
Pernicious Anaemia Society
1 month ago
MMA result
Hi allJust got medichecks result which shows high lMMA level: 34.8ug/l (less than 32) Previous medichecks active B12 was 48.1 pmol/l (37.5-150) (they advised MMA test) Intrinsic factor antibodies negative (mum had PA) Does high MMA result indicate a functional b12 deficiency as opposed to dietary deficiency
Hi allJust got medichecks result which shows high lMMA level: 34.8ug/l (less than 32) Previous medichecks active B12 was 48.1 pmol/l (37.5-150) (they advised MMA test) Intrinsic factor antibodies negative (mum had PA) Does high MMA result indicate a functional b12 deficiency as opposed to dietary deficiency
Hollybushroad
in
Pernicious Anaemia Society
10 months ago
Figuring things out - first year since diagnosis
Hi, I'm posting here as I don't know anyone in real life with lupus and have been struggling to work out what my expectations should be in terms of symptoms. I was diagnosed just over a year ago following about a year of strange symptoms - GI issues, weight loss, Raynaud's, mouth ulcers, hand and wrist
Hi, I'm posting here as I don't know anyone in real life with lupus and have been struggling to work out what my expectations should be in terms of symptoms. I was diagnosed just over a year ago following about a year of strange symptoms - GI issues, weight loss, Raynaud's, mouth ulcers, hand and wrist
CGSLE
in
LUPUS UK
2 months ago
Suspected Pernicious Anemia - what next?
Hello, I am very glad to have found this forum as I have been researching B12D and PA a lot recently. I became familiar with the society’s website and found it so helpful. I am 29F in the US and I suspect I have Pernicious Anemia. This is what I know so far (sorry in advance if this post rambles on)
Hello, I am very glad to have found this forum as I have been researching B12D and PA a lot recently. I became familiar with the society’s website and found it so helpful. I am 29F in the US and I suspect I have Pernicious Anemia. This is what I know so far (sorry in advance if this post rambles on)
Marlowekat
in
Pernicious Anaemia Society
2 months ago
Low B12 and ferritin questions
It was only when
I
asked about the intrinsic
factor
test
that they then agreed to test for it. On the one hand, I am happy I now have supplements but I'm worried that oral supplements won't be enough and injections might be better. Is there any reason the dr wouldn't prescribe me injections?
It was only when
I
asked about the intrinsic
factor
test
that they then agreed to test for it. On the one hand, I am happy I now have supplements but I'm worried that oral supplements won't be enough and injections might be better. Is there any reason the dr wouldn't prescribe me injections?
bakedbean5007
in
Pernicious Anaemia Society
2 days ago
Castor Oil Packs
Have any of you tried this? Was recommended to me by a natural therapist, she has a client who it really helped. Below are links to what they do. https://healf.com/blogs/health-journal/what-are-castor-oil-packs-how-do-they-work-and-what-do-they-do https://thewellnessjunction.com/the-benefits-of-using-castor-oil-packs-for-your-thyroid
Have any of you tried this? Was recommended to me by a natural therapist, she has a client who it really helped. Below are links to what they do. https://healf.com/blogs/health-journal/what-are-castor-oil-packs-how-do-they-work-and-what-do-they-do https://thewellnessjunction.com/the-benefits-of-using-castor-oil-packs-for-your-thyroid
Nomad12
in
Thyroid UK
3 days ago
lapararoscopy
I have a complex cyst probably 7.2-7.4cm and have been told that I will need eventual laparascopy. I am back 23rd of July again for another tvultrasound to check how it is. The gynae/surgeon has done watchful waiting with me since my diagnosis as he knows I am a carer for my mum and I have no one else
I have a complex cyst probably 7.2-7.4cm and have been told that I will need eventual laparascopy. I am back 23rd of July again for another tvultrasound to check how it is. The gynae/surgeon has done watchful waiting with me since my diagnosis as he knows I am a carer for my mum and I have no one else
Ova104
in
My Ovacome
4 days ago
Do those with thin linings have light periods?
Hello,I have unexplained infertility. Have had one failed cycle that produced 3 good quality blasts. 1 x fresh failed and 2 x FET both failed to implant. I had one cycle cancelled due to thin lining of 5.5mm. I now take additional estrogen, Viagra, Aspirin and progesterone which have given me a lining
Hello,I have unexplained infertility. Have had one failed cycle that produced 3 good quality blasts. 1 x fresh failed and 2 x FET both failed to implant. I had one cycle cancelled due to thin lining of 5.5mm. I now take additional estrogen, Viagra, Aspirin and progesterone which have given me a lining
AmyG18
in
Fertility Network UK
4 days ago
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