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Heterogeneous Metastases?
I was first diagnosed Stage3 in Aug. 2014, ER+PR+Her2-. Found metastases in bones and lymph nodes in Dec. 2023, bioposied one node, same biomarkers. I was put on Tamoxifen which shrank many lesions, except for one. After that, I went through Tamoxifen, Letrozole + Kisqali, Faslodex + Kisqali, have scan
I was first diagnosed Stage3 in Aug. 2014, ER+PR+Her2-. Found metastases in bones and lymph nodes in Dec. 2023, bioposied one node, same biomarkers. I was put on Tamoxifen which shrank many lesions, except for one. After that, I went through Tamoxifen, Letrozole + Kisqali, Faslodex + Kisqali, have scan
Faith999
in
SHARE Metastatic Breast Cancer
7 months ago
Atelectasis?
I have seen several people refer to this here, but didn't know what it was. My PET/CT scan on Friday showed some mildly alarming things -- bone met in spine is shrinking, but a bunch of subcentimeter but metabolically active lymph nodes around the lungs (hila, paratrachea, mediastinal-pleural). Not
I have seen several people refer to this here, but didn't know what it was. My PET/CT scan on Friday showed some mildly alarming things -- bone met in spine is shrinking, but a bunch of subcentimeter but metabolically active lymph nodes around the lungs (hila, paratrachea, mediastinal-pleural). Not
TammyCross
in
SHARE Metastatic Breast Cancer
7 months ago
IBS / Diverticulosis
Does anyone suffer from a flare , UTI and diverticulitis at the same time ? This last flare started after a course of antibiotics for another infection. , but now I have felt really ill for the last few days with very tender abdomen and pain all along my left side even up under my left ribs ! I also
Does anyone suffer from a flare , UTI and diverticulitis at the same time ? This last flare started after a course of antibiotics for another infection. , but now I have felt really ill for the last few days with very tender abdomen and pain all along my left side even up under my left ribs ! I also
Mascot68
in
IBS Network
4 months ago
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stomach bloating
I have pain starting from stomach then it seems to travel down to lower abdomen. I am very bloated, only burping or passing wind, my pain can be released a bit. The bloating is so bad, I couldn’t even breathe. I am wondering if anyone who have similar symptoms and how to relief such painful bloating.
I have pain starting from stomach then it seems to travel down to lower abdomen. I am very bloated, only burping or passing wind, my pain can be released a bit. The bloating is so bad, I couldn’t even breathe. I am wondering if anyone who have similar symptoms and how to relief such painful bloating.
Stomach2024
in
IBS Network
4 months ago
Help and understanding
Hi all, let me start with how much I love this site everyone is so helpful and understanding. I'm sorry if I go on a bit just sometimes things seem better when you write it down and get anothers view. I've had ibs c for 30 ish years. It was just constant constipation in the beginning. As the years went
Hi all, let me start with how much I love this site everyone is so helpful and understanding. I'm sorry if I go on a bit just sometimes things seem better when you write it down and get anothers view. I've had ibs c for 30 ish years. It was just constant constipation in the beginning. As the years went
Gizmo6
in
IBS Network
4 months ago
what is ibs?
Hi! new here and didn’t actually know this forum was about until I started googling on the nhs site. So my question is what is ibs? I want to explain what I’m experiencing and if someone can tell me if it’s completely normal for ibs to be like this I would be really grateful. This time last year
Hi! new here and didn’t actually know this forum was about until I started googling on the nhs site. So my question is what is ibs? I want to explain what I’m experiencing and if someone can tell me if it’s completely normal for ibs to be like this I would be really grateful. This time last year
HLeamon
in
IBS Network
4 months ago
Ca125 huge rise please help
My mother 's Ca 125 had a huge Spike from 2.74 last november to 11.42 at the begininng of May. CEA went Down instead. She changed Lab and this new Lab has a different range, the previous One used 0-21 and this One use the usual 0-35. She also had a ct scan , absolutely clear. She had , 15 days prior
My mother 's Ca 125 had a huge Spike from 2.74 last november to 11.42 at the begininng of May. CEA went Down instead. She changed Lab and this new Lab has a different range, the previous One used 0-21 and this One use the usual 0-35. She also had a ct scan , absolutely clear. She had , 15 days prior
Belindajames
in
My Ovacome
4 months ago
Reaction to Taxol (Paclitaxel) and alternatives?
Hi- I was diagnosed with primary peritoneal cancer in Jan 2024. I had my first chemo last week and reacted to the taxol (paclitaxel) so could only receive bev and carboplatin. I will be switched to taxotere for my next treatment. Wondering if anyone else has had a reaction to taxol and then received
Hi- I was diagnosed with primary peritoneal cancer in Jan 2024. I had my first chemo last week and reacted to the taxol (paclitaxel) so could only receive bev and carboplatin. I will be switched to taxotere for my next treatment. Wondering if anyone else has had a reaction to taxol and then received
ajtbq
in
SHARE Ovarian Cancer Support
7 months ago
Ranolazine (used for angina) could potentially be repurposed for PCa. Only mouse studies so far.
“Treatment of cancer patients with lipid metabolic inhibitors like ranolazine could potentially re-activate the immune cells to restore and enhance cellular-mediated antitumor immunity and tumor regression.” Targeting Fat Oxidation in Mouse Prostate Cancer Decreases Tumor Growth and Stimulates Anti-Cancer
“Treatment of cancer patients with lipid metabolic inhibitors like ranolazine could potentially re-activate the immune cells to restore and enhance cellular-mediated antitumor immunity and tumor regression.” Targeting Fat Oxidation in Mouse Prostate Cancer Decreases Tumor Growth and Stimulates Anti-Cancer
Graham49
in
Advanced Prostate Cancer
7 months ago
Esomeprazole and metoclopramide
Hello everyone I’ve been enjoying the posts on What’s in a Title and thank you to all involved. On a more mundane matter, I had a telephone consultation with I’m pleased to say, Dr Murray’s gastrointestinal/Scleroderma clinic over a week ago. It was with Kristina Clarke who I’ve met before and when
Hello everyone I’ve been enjoying the posts on What’s in a Title and thank you to all involved. On a more mundane matter, I had a telephone consultation with I’m pleased to say, Dr Murray’s gastrointestinal/Scleroderma clinic over a week ago. It was with Kristina Clarke who I’ve met before and when
Halfwayuphill
in
Scleroderma & Raynaud's UK (SRUK)
4 months ago
Happy holiday post!
Quick catch up to give a boost if you're struggling right now starting your journey 😘 Basics Stage4b hgsc hrd+ brca negative with lymph nodes next to my heart and pelvis, started carbo/taxol June 2021 had 4 rounds then paid private for operation then 2 rounds. Finished 22 infusions of avastin in April
Quick catch up to give a boost if you're struggling right now starting your journey 😘 Basics Stage4b hgsc hrd+ brca negative with lymph nodes next to my heart and pelvis, started carbo/taxol June 2021 had 4 rounds then paid private for operation then 2 rounds. Finished 22 infusions of avastin in April
Newbery3
in
My Ovacome
4 months ago
Stomach pain bam
Got diagnosed with bile acid malabsorption over a year ago terrible pain before and after bowel movements that lasts a good few hours seeing a different doctor at my surgery he said he could be the bile salts aggravating my colon so i have to up the colesevelam to 2 a day instead of 1 if that dont help
Got diagnosed with bile acid malabsorption over a year ago terrible pain before and after bowel movements that lasts a good few hours seeing a different doctor at my surgery he said he could be the bile salts aggravating my colon so i have to up the colesevelam to 2 a day instead of 1 if that dont help
Netbet22
in
IBS Network
4 months ago
Result of Liver Biopsy - Any Insights?
This is the result of my liver biposy. Any insights on the comment? ----- CLINICAL HISTORY>>:: Prostate Ca with hepatic mets ?Small cell transformation versus other. FINAL DIAGNOSIS>>:: LIVER NODULE, CORE BIOPSY: - POORLY DIFFERENTIATED PROSTATIC ADENOCARCINOMA WITH SMALL CELL TRANSFORMATION
This is the result of my liver biposy. Any insights on the comment? ----- CLINICAL HISTORY>>:: Prostate Ca with hepatic mets ?Small cell transformation versus other. FINAL DIAGNOSIS>>:: LIVER NODULE, CORE BIOPSY: - POORLY DIFFERENTIATED PROSTATIC ADENOCARCINOMA WITH SMALL CELL TRANSFORMATION
skiingfiend
in
Advanced Prostate Cancer
7 months ago
not PCa related but promising in vivo therapy for cancer metastasis
”The polymer eliminates colorectal cancer liver metastases and prolongs mice survival, after only a single-dose therapy. The findings were published in Nano Today, a leading journal in the field of nanotechnology.” https://m.jpost.com/health-and-wellness/article-795801
”The polymer eliminates colorectal cancer liver metastases and prolongs mice survival, after only a single-dose therapy. The findings were published in Nano Today, a leading journal in the field of nanotechnology.” https://m.jpost.com/health-and-wellness/article-795801
Maxone73
in
Advanced Prostate Cancer
6 months ago
High risk vs. aggressive cancer
I understand the definition of high-risk prostate cancer (Gleason, PSA and/or spread), but that doesn't necessarily seem to be the same thing as aggressive cancer. How can aggressiveness be determined for high risk, localized cancer? Thanks for any insight and information.
I understand the definition of high-risk prostate cancer (Gleason, PSA and/or spread), but that doesn't necessarily seem to be the same thing as aggressive cancer. How can aggressiveness be determined for high risk, localized cancer? Thanks for any insight and information.
RugbyVLS
in
Advanced Prostate Cancer
7 months ago
Is my Endo back?
Hi Everyone, Looking for some advice or anyone who's been through a similar experience. I had Endo 3 years ago some of my main symptoms where bowel issues bloating, gassy, stomach cramps and diarrhea whenever I ate to much. Initially the doctor put it down to IBS. Obviously that wasn't the case and it
Hi Everyone, Looking for some advice or anyone who's been through a similar experience. I had Endo 3 years ago some of my main symptoms where bowel issues bloating, gassy, stomach cramps and diarrhea whenever I ate to much. Initially the doctor put it down to IBS. Obviously that wasn't the case and it
mo222
in
Endometriosis UK
4 months ago
Simethicone
Been having problems due to Pelvic Floor Dysfunction. Whilst it’s improved a little bit in the last few days I’m finding that trapped gas first thing when waking is an issue. I was looking at Simethicone and whether that or Deflatine would help me. I’ve got afib and on regular medication (flec and bisoprolol
Been having problems due to Pelvic Floor Dysfunction. Whilst it’s improved a little bit in the last few days I’m finding that trapped gas first thing when waking is an issue. I was looking at Simethicone and whether that or Deflatine would help me. I’ve got afib and on regular medication (flec and bisoprolol
Profound15
in
Atrial Fibrillation Support
4 months ago
High dose Turmeric and links to low ferritin
My ferritin has dropped from 82ug/L (30-150) 4 months ago to 64ug/L (30-264) this week (both Medichecks- Inuvi lab). I’ve been scratching my head to find out why this could be, as my diet hasn’t changed. https://amzn.eu/d/bTWoF2o The only change I’ve made is to increase my usual turmeric dose (which
My ferritin has dropped from 82ug/L (30-150) 4 months ago to 64ug/L (30-264) this week (both Medichecks- Inuvi lab). I’ve been scratching my head to find out why this could be, as my diet hasn’t changed. https://amzn.eu/d/bTWoF2o The only change I’ve made is to increase my usual turmeric dose (which
Buddy195
Administrator
in
Thyroid UK
4 months ago
brachytherapy
my hubbie has just had brachytherapy for stage 3 prostate and has been in great pain since Thursday. He’s been told it’s normal and to suck it up but he’s not sleeping and is struggling to wee without great pain (tears) . Any advice as to what has worked for you to manage post op brachytherapy please
my hubbie has just had brachytherapy for stage 3 prostate and has been in great pain since Thursday. He’s been told it’s normal and to suck it up but he’s not sleeping and is struggling to wee without great pain (tears) . Any advice as to what has worked for you to manage post op brachytherapy please
bikebabe
in
Prostate Cancer Network
7 months ago
hepatic Encephalopathy
morning, can anyone advice me about hepatic Encephalopathy ? I have stage 4 liver desease and was feeling so confused last night with things like time and thinking lights were off but were on is this the start of it? Last time I was like this was last march when I had my diagnoses, I take lactose which
morning, can anyone advice me about hepatic Encephalopathy ? I have stage 4 liver desease and was feeling so confused last night with things like time and thinking lights were off but were on is this the start of it? Last time I was like this was last march when I had my diagnoses, I take lactose which
Kingbilly3
in
British Liver Trust
4 months ago
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