I have had leg pain for a number of years. My movement disorder specialist has insisted that this is not a symptom of Parkinson's. In any case, I had my general practitioner put me on gabapentin to see if that would help with the pain. It actually helped for a short time, but then it stopped working- quite disappointing. In any case, since it was no longer working I have been titrating down and I recently stopped taking it all together. Surprisingly, I have noticed that along with my stopping the Gabapentin, my Tremor and other Parkinson's symptoms seem to have gotten worse. I understand that Gabapentin works on dopamine in the brain. Is it possible that the Gabapentin was helping me with some of my Parkinson's symptoms? Have any of you noticed a correlation between the use of gabapentin and the relief of Parkinson's symptoms? I know it is not indicated for this use, but correlation seems quite curious. Any and all stories regarding gabapentin and Parkinson's are appreciated!
Gabapentin and Parkinson's : I have had leg... - Cure Parkinson's
Gabapentin and Parkinson's


Didn't do anything for me except cause a significant weight gain. My GP wanted to increase the dose but I decided against.
I'll be interested to see any replies to your post, Parkieperson because I've got an appointment with a neuropsychiatrist in a couple of weeks, and I was hoping to be prescribed Gabapentin (or Pregabalin) for anxiety.
If you experience anxiety at all, did the Gabapentin help with that?
I've read (somewhere!) that Gabapentinoids can ease PD symptoms so it's interesting to hear it helped with yours.
As anxiety itself can exacerbate PD symptoms - perhaps one reason it works is because it reduces anxiety?
I have been prescribed Gabapentin by my Neurologist for my restless legs at night. I only take it when I can't sleep due to that.... It does help. And I do believe it helps my aching muscles that are more noticeable at night. I was told that I can take up to 300mg if needed. I. usually on take 200mg. I am not sure the "how" behind it, but it seems to help. I never take it during the day because it seems to make me more tired.
Be careful with Gapapentin. It has dopamine inhibitory effects. Might try a TENs unit or another approved device to help with leg cramps, dystonia like this unit:
I am on Gabapentin for Parkinson’s pain. I can’t move without the Gabapentin. The pain, tingling and numbness is what I was most concerned about when I first went to my Neurologist. I know these symptoms are generally discussed as neuropathy but they were extremely irritating. The gabapentin took care of those for sure. I had only a short time with only carbadopa/levodopa. I know without the Gabapentin I would be extremely uncomfortable with pain, tingling and numbness. For me 10 years ago, the c/l only took care of the tremor.
See this study, it's a bit dated, but science is science: pubmed.ncbi.nlm.nih.gov/920....
On a personal note I take some of my wife's gabapentin for insomnia and it works wonders. She takes if for restless leg and hot flashes and it works for her for those things with no side effects. We both take it at night so the drowsiness side effect is not a problem
have you tried PEA
pmc.ncbi.nlm.nih.gov/articl...
No I haven't. I haven't even heard of it. I read the article and it looks very promising. The Gabapentin and low dose Naltrexone are working for me now, so I probably won't try anything new unless these stop working. Are you on PEA?