Dopamine Expert: Doing This Once A Day Fixes Your Dopamine! What Alcohol Is Doing To Your Brain!!

[LAJ12345]

This is a must watch.

youtube.com/watch?v=R6xbXOp...(Not working as expected?)

Dr Anna Lembke is Professor of Psychiatry at Stanford University School of Medicine and chief of the Stanford Addiction Medicine Dual Diagnosis Clinic. She is the author of bestselling books such as, ‘Dopamine Nation: Finding Balance in the Age of Indulgence’.

00:00 Intro

03:44 Why Does Dopamine Matter?

04:08 What Is Dopamine?

05:35 How Understanding Dopamine Can Improve Your Life

06:09 Biggest Misconceptions About Dopamine

07:30 Everyday Activities That Impact Dopamine

09:36 Dopamine and Its Relationship to Pleasure and Pain

18:26 Why Do Our Brains Overshoot?

20:31 How Our Brains Are Wired for Addiction

25:22 Finding Ways to Deal With Pain

31:51 Stories of Addiction

34:52 How Many People Have Addiction Disorders?

40:14 Hiding Away From Friends and Family

41:21 Distinguishing Between Good and Bad Behaviors

45:50 How Addiction Makes You Feel

47:50 Is Work an Addiction?

54:18 What Activities Provide the Biggest Dopamine Hits?

58:59 Can We Inject or Drink Dopamine?

01:01:00 Why We Must Do Hard Things

01:02:37 Can You Get an Exercise Comedown?

01:04:19 How to Optimize for a Better Life

01:05:17 How Should We Be Living?

01:09:29 Being Comfortable With the Uncomfortable

01:10:34 Causes of Anxiety Throughout Life

01:12:43 Living in a World Where It's Easy to Outrun Pain

01:13:09 Where Are You Now in Your Grieving Journey?

01:14:43 Youngest Child Seen With Addictions

01:15:37 Youngest Age When Addiction Can Have an Effect

01:16:50 Youngest Patient With Addiction

01:18:40 Has Society Gone Soft?

01:21:05 Victimhood and Responsibility

01:25:02 How to Help Someone Overcome a Victimhood Mentality

01:28:36 Connection Between Responsibility and Self-Esteem

01:30:13 Importance of Our Self-Narrative

01:37:24 Ads

01:38:22 How Helping a Loved One Too Much Can Hurt Them

01:44:49 Overcoming Pornography Addiction

01:48:35 Harms of Watching Porn

01:51:04 Is Dopamine Responsible for Sugar Cravings?

01:53:05 Turning Addictions Around

01:58:25 Why We Bounce Back to Cravings After Relapsing

02:02:49 Effects of Early Exposure to Addictive Substances on Children

02:04:43 Final Thoughts on Overcoming Addiction

02:05:39 Closing Remarks

02:07:38 What Information Changed Your Life?

[JayPwP]

Thank you 🙏

[LAJ12345 in reply to JayPwP]

Did you listen to it? She has such an interesting view point.

[JayPwP in reply to LAJ12345]

I saw some and saved the rest for later.

[JayPwP]

At 59:15 they touch on PD, but I was unable to understand her.

[LAJ12345 in reply to JayPwP]

Her accent or what she was saying?

[JayPwP in reply to LAJ12345]

What she was saying... The last 2 timelines in the screenshot

Screenshot

[park_bear in reply to JayPwP]

Impulse control disorders are mainly a problem for dopamine agonist users:

pubmed.ncbi.nlm.nih.gov/299...

"In 306 patients without ICDs at baseline, the 5-year cumulative incidence of ICDs was 46.1% (95% confidence interval [CI] 37.4–55.7, DA [dopamine agonist] ever users 51.5% [95% CI 41.8–62.1], DA never users 12.4% [95% CI 4.8–30.0])."

[JayPwP in reply to park_bear]

She says when L-Dopa is given exogenously, the body compensates by down regulating dopamine transmission???

This part I didn't understand...

[park_bear in reply to JayPwP]

That may apply to healthy people with normal dopamine levels. I doubt that it is the case in Parkinson's.

[JayPwP in reply to park_bear]

I agree with you but she seems to say that

[park_bear in reply to JayPwP]

Someone's comment is not the same as a study published in a peer reviewed journal, even if that person really is an expert.

[LAJ12345 in reply to JayPwP]

It might be that once you start taking the l dopa your body makes less thinking it doesn’t need it. Better to exercise to make some and take minimum meds? At least in the early stages. Later on it might not work.

[00Mark in reply to JayPwP]

I've heard Robert Sapolsky talking about this down-regulating business. Basically, if there is more dopamine in the brain, the neurons which react to it dial down their sensitivity (reduce the number of dopamine receptors). This can be reversed over time if dopamine levels are reduced.But as Park Bear says, this is in healthy brains.

[Tinkerbelle55 in reply to JayPwP]

So what’s the answer?

[JayPwP in reply to Tinkerbelle55]

Good question...

[LAJ12345 in reply to Tinkerbelle55]

I’m not sure with respect to people who have had PD and been on meds for a long time.

But she seems to say stop doing any addictive behaviour as that gives dopamine hits that the body balances out with ‘pain’ in her scales analogy. Exercise does the opposite by spending the ‘pain’ up front and to balance the body produces dopamine if able. I think.

[Meg024 in reply to LAJ12345]

Excellent interview. Thanks for posting. You summed it up well. I've been following Anna's Lembke's drift with increased exercise and reduced L-dopa for the past year and I think of it in terms of releasing endorphins from the fun and pleasure of walking my dog and meditating on the goodness of God, and playing squash on my own. Maldonado also recommends this drift, only he encourages HIIT. I can't do HIIT. Bradykinesia limits my speed. So my squash is slow and steady, long rallies, not running for the ball so much as hitting it right back to me. The initial high was euphoric when I only had energy for 12 minutes. Now I keep it up for 30 minutes in a more meditative tempo. Dopamine seems to have a love of novelty embedded in its nature, hence the surprisingly good results when one FIRST makes a dosing change.

[LAJ12345 in reply to Meg024]

Interesting.

[Smittybear7]

thank you how do you subscribe?

[LAJ12345 in reply to Smittybear7]

If you hit watch on YouTube there is a subscribe button on that page

I find most of his interviews really good. Diary of a CEO. The one about body language is fascinating too.

[Salted]

Wow, I haven't had time to watch a 2 hour video yet. But what is the thing to do once a day that will "fix" dopamine?

[LAJ12345 in reply to Salted]

I actually didn’t hear her specifically say but what I got from it is stop doing addictive things like drugs alcohol sugar eating junk watching TV doom scrolling, internet games or social media, even shopping or over exercising over working, watching porn….. for her it was reading racy novels was taking her away from her kids.

Whatever it is that takes you away from being in the present with the people you are with or that you can’t seem to stop.

Then exercise (a sensible amount) mindfulness, almost emptying your mind of noise and just being present enjoying the moment. Also doing hard things and not trying to make everything easy for yourself.

She say even things that shouldn’t be addictive have been drugified (designed to give a dopamine hit) Ie fitness apps and leaderboards to make exercise addictive. Etc

[Esperanto in reply to LAJ12345]

The extent of the desired withdrawal is overlooked. While one might argue that sugar intake in youth can lead to a lifelong susceptibility to addiction, this offers little practical guidance. For Parkinson's disease, the situation is even more complex. A certain level of levodopa stimulation is sometimes necessary to help us function effectively. Each individual must find their own balance in this regard. However, understanding the mechanisms of dopamine is essential in navigating this journey. 🙏

[LAJ12345 in reply to Esperanto]

Yes. This is a general expert on dopaminenot a PD specialist so she is mostly talking to people who have addictive behaviours. Potentially they may go on to develop PD if they don’t modify their behaviour.

We are the first few generations to experience such an over load of dopamine over stimulation from many new spheres. Except for the use of alcohol and some drugs that have been available for a long time technology and junk food are quite new. However these don’t necessarily affect everyone, but she thinks for most people they have their own drug or activity of choice that creates addictive behaviour.

[LAJ12345 in reply to Salted]

Try watching on faster speed. I’m from New Zealand and I find especially people from US speak very slowly so I can usually watch on 1.5 speed. Although he is British so watch him on 1.25

[NiccNZ in reply to LAJ12345]

Ha, true.