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Next NoSilverBullet webinar on 17th of June: Sackner-Bernstein, MD, on "Why I am optimistic that we might now have a Silver Bullet for PD".
I am delighted to announce that our next NoSilverBullet Zoom webinar will be taking place at 7.30pm London time on Monday, the 17th of June. Jonathan Sackner-Bernstein, MD, will be talking to us about "Why I am optimistic that we might now have a Silver Bullet for PD". Please use the Eventbrite link
I am delighted to announce that our next NoSilverBullet Zoom webinar will be taking place at 7.30pm London time on Monday, the 17th of June. Jonathan Sackner-Bernstein, MD, will be talking to us about "Why I am optimistic that we might now have a Silver Bullet for PD". Please use the Eventbrite link
Michel0220
in
Cure Parkinson's
2 months ago
The 40 Hz flickering light restores synaptic plasticity and mitochondrial phenotype in experimental model of Alzheimer's disease May 2024
The 40 Hz flickering light restores synaptic plasticity and mitochondrial phenotype in experimental model of Alzheimer's disease May 2024
- https://www.researchgate.net/publication/380600451_The_40_Hz_flickering_light_restores_synaptic_plasticity_and_mitochondrial_phenotype_in_experimental_model_of_Alzheimer
The 40 Hz flickering light restores synaptic plasticity and mitochondrial phenotype in experimental model of Alzheimer's disease May 2024
- https://www.researchgate.net/publication/380600451_The_40_Hz_flickering_light_restores_synaptic_plasticity_and_mitochondrial_phenotype_in_experimental_model_of_Alzheimer
Bolt_Upright
in
Cure Parkinson's
2 months ago
The Stimulation-Happiness Link: Your Experiences?
Do any of you recognize this: I want to explore the issue of lack of stimulation and my low mood. It's shocking how much one really leads to the other.
When I have stimulation, I feel alive, alert, happy, and content.
Even if (or perhaps because) there's pressure. But
when I have nothing engaging
Do any of you recognize this: I want to explore the issue of lack of stimulation and my low mood. It's shocking how much one really leads to the other.
When I have stimulation, I feel alive, alert, happy, and content.
Even if (or perhaps because) there's pressure. But
when I have nothing engaging
dopamin
in
CHADD's Adult ADHD Support
2 months ago
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Medscape article on RLS
Restless legs Medscape Medscape is the leading online global destination for physicians and healthcare professionals worldwide, offering the latest medical news and expert perspectives; essential point-of-care drug and disease information; and relevant professional education and CME. This is
Restless legs Medscape Medscape is the leading online global destination for physicians and healthcare professionals worldwide, offering the latest medical news and expert perspectives; essential point-of-care drug and disease information; and relevant professional education and CME. This is
thorp
in
Restless Legs Syndrome
2 months ago
Don’t Light the Fuse of Restless Legs Syndrome with Dopamine Agonists - Excellent Article
https://sleepreviewmag.com/sleep-treatments/pharmaceuticals/prescription-drugs/restless-legs-syndrome-dopamine-agonists/ This is now a Pinned Post
https://sleepreviewmag.com/sleep-treatments/pharmaceuticals/prescription-drugs/restless-legs-syndrome-dopamine-agonists/ This is now a Pinned Post
Kaarina
Administrator
in
Restless Legs Syndrome
2 months ago
I don’t know if I want to get better
In my heart, I know I really do want to live a better life. I’m miserable and sad and wasting my precious time here. But at the same time, I don’t want to put in the work to get better. I’m pissed that it doesn’t come naturally like it does for others. I also don’t know what makes me feel joy. Nothing
In my heart, I know I really do want to live a better life. I’m miserable and sad and wasting my precious time here. But at the same time, I don’t want to put in the work to get better. I’m pissed that it doesn’t come naturally like it does for others. I also don’t know what makes me feel joy. Nothing
Strugglingblonde13
in
Major Depressive Disorder (MDD) Support
2 months ago
I don’t care which supplement is working.
I feel awesome; the combo could be placebo. Today I took: - 2 scoops of Inulin and a Probiotic first thing in the morning. My whole body felt tingly for 45 minutes. (Tingly may be the wrong word, it wasn’t unpleasant, more like a glow.) - Hour later: 1 Neurogan’s Urolithin A 700mg, 1 Fatty15, 1-1/
I feel awesome; the combo could be placebo. Today I took: - 2 scoops of Inulin and a Probiotic first thing in the morning. My whole body felt tingly for 45 minutes. (Tingly may be the wrong word, it wasn’t unpleasant, more like a glow.) - Hour later: 1 Neurogan’s Urolithin A 700mg, 1 Fatty15, 1-1/
Gcf51
in
Cure Parkinson's
2 months ago
Buprenorphine
I thought I would share my story . I live in Gloucestershire and have suffered with chronic rls for over 30 yrs Dopamine Agonists worked quite well until I hit augmentation last year. Getting off them was hell and was often suicidal . This forum saved my life. Last month I finally got put on Buprnorphine
I thought I would share my story . I live in Gloucestershire and have suffered with chronic rls for over 30 yrs Dopamine Agonists worked quite well until I hit augmentation last year. Getting off them was hell and was often suicidal . This forum saved my life. Last month I finally got put on Buprnorphine
Huntingleroy
in
Restless Legs Syndrome
2 months ago
Need a good psychiatrist who doesn't mind writing off-label prescriptions.
My doctor won't prescribe "off label" drugs. And I just got a dear john letter basically saying good luck. Get help elsewhere. I'm in California, but willing to do telemedicine. I have seen two psychiatrists that are basically singing the same song. No, off label drugs. They are just giving me the
My doctor won't prescribe "off label" drugs. And I just got a dear john letter basically saying good luck. Get help elsewhere. I'm in California, but willing to do telemedicine. I have seen two psychiatrists that are basically singing the same song. No, off label drugs. They are just giving me the
RanchoguyCA
in
CHADD's Adult ADHD Support
2 months ago
medication rotation
My RLS doctor, who I have found to be most knowledgeable about RLS put me on Buprenorphine,( .5 mg is my lowest effective dose). I was on Pramipexole without significant augmentation, but discontinued gradually after starting the Bup. After a year of Bup only, after the dopamine receptors have “reset
My RLS doctor, who I have found to be most knowledgeable about RLS put me on Buprenorphine,( .5 mg is my lowest effective dose). I was on Pramipexole without significant augmentation, but discontinued gradually after starting the Bup. After a year of Bup only, after the dopamine receptors have “reset
teakabeagle
in
Restless Legs Syndrome
2 months ago
methadone ? Tolerance
hi, I am wondering if I am developing a tolerance to methadone, and, if so, where too from here? Sorry about the long post but I think if anyone is able to help me, they will need details. Aafter augmenting repeatedly on dopamine agonists I finally withdrew from them cold turkey on on 2 Dec 23, not
hi, I am wondering if I am developing a tolerance to methadone, and, if so, where too from here? Sorry about the long post but I think if anyone is able to help me, they will need details. Aafter augmenting repeatedly on dopamine agonists I finally withdrew from them cold turkey on on 2 Dec 23, not
Mongolia2020
in
Restless Legs Syndrome
2 months ago
Links between TSH and RLS. Have I found my cause in sub clinical hypothyroidism due to autoimmune disease Hashimoto syndrome?
As my RLS was under pretty good control I decided to see how I would go if I stopped my Tramadol 50-100mg daily, and tried CBD/THC oil instead. The answer was badly. My symptoms came back to the point I barely slept for 6 nights. And of course I also had withdrawal symptoms to deal with. As most of
As my RLS was under pretty good control I decided to see how I would go if I stopped my Tramadol 50-100mg daily, and tried CBD/THC oil instead. The answer was badly. My symptoms came back to the point I barely slept for 6 nights. And of course I also had withdrawal symptoms to deal with. As most of
TheGiz
in
Restless Legs Syndrome
2 months ago
Dopamine
I just read that dopamine is made in the adrenals I had not heard this in the past so I am wondering what does this all mean? So maybe there is dopamine being made but the cells can't use it properly? "Dopamine, epinephrine and norepinephrine are the main catecholamines (a label based on having part
I just read that dopamine is made in the adrenals I had not heard this in the past so I am wondering what does this all mean? So maybe there is dopamine being made but the cells can't use it properly? "Dopamine, epinephrine and norepinephrine are the main catecholamines (a label based on having part
Boscoejean
in
Cure Parkinson's
2 months ago
Update on STEM-PD clinical trial – stem cell-based transplant for Parkinson’s disease
Higher dose cohort initiated after positive early safety evaluation in Parkinson's therapy. After a positive initial safety evaluation, the pioneering STEM-PD clinical trial has advanced to higher dose testing. STEM-PD is a first-in-human clinical trial testing a new investigational therapy for Parkinson
Higher dose cohort initiated after positive early safety evaluation in Parkinson's therapy. After a positive initial safety evaluation, the pioneering STEM-PD clinical trial has advanced to higher dose testing. STEM-PD is a first-in-human clinical trial testing a new investigational therapy for Parkinson
nednedned
in
Cure Parkinson's
2 months ago
PLMD medication
Hello I just joined because i was recently diagnosed with PLMD. The doctors don't really seem very informed about this condition. My ferritin level was fine around 200 so I decided to not supplement that even though the hospital advised me to. I then went onto take Pramipexole (didn't help) for
Hello I just joined because i was recently diagnosed with PLMD. The doctors don't really seem very informed about this condition. My ferritin level was fine around 200 so I decided to not supplement that even though the hospital advised me to. I then went onto take Pramipexole (didn't help) for
drover123
in
Restless Legs Syndrome
2 months ago
Facing thyroid surgery?
Have you been told that you're hyperthyroid, and / or been told that you need to have your thyroid removed – but you're not convinced because your symptoms don't seem to match the diagnosis? That's exactly where I was nine years ago – and I want to urge you to follow your instincts ! To put it simply
Have you been told that you're hyperthyroid, and / or been told that you need to have your thyroid removed – but you're not convinced because your symptoms don't seem to match the diagnosis? That's exactly where I was nine years ago – and I want to urge you to follow your instincts ! To put it simply
Indiethinker
in
Thyroid UK
2 months ago
Gabapentin Hell!
Hi all, thought I would share my recent experience with Gabapentin. I have had RLS since I was 18 and am now 74. I started on Pramipexole about 15 years ago 0.18mgs and as predicted it has got steadily worse so increased it to 0.36mgs 6 years ago along with co codamol. Once again it has got worse and
Hi all, thought I would share my recent experience with Gabapentin. I have had RLS since I was 18 and am now 74. I started on Pramipexole about 15 years ago 0.18mgs and as predicted it has got steadily worse so increased it to 0.36mgs 6 years ago along with co codamol. Once again it has got worse and
jeanjack
in
Restless Legs Syndrome
2 months ago
Mildly Burning After Withdrawing From Neupro
Hi All, As I have posted before, recently I withdrew from Neupro with the help of Buprenorphine. It has been 6 weeks now without any dopamine agonist and my experience has been overwhelmingly positive. Unfortunately, issues have come up recently that I thought someone might be able shine some light
Hi All, As I have posted before, recently I withdrew from Neupro with the help of Buprenorphine. It has been 6 weeks now without any dopamine agonist and my experience has been overwhelmingly positive. Unfortunately, issues have come up recently that I thought someone might be able shine some light
RiversW
in
Restless Legs Syndrome
3 months ago
Unleashing the Power of Intensive Brain Training in Parkinson's: Promising Findings
Discover the captivating effects of intensive brain training in Parkinson's disease. This study focused on a group of individuals recently diagnosed with Parkinson's and in relatively good condition. Over a six-month period, they engaged in a rigorous training program under supervision. The intensive
Discover the captivating effects of intensive brain training in Parkinson's disease. This study focused on a group of individuals recently diagnosed with Parkinson's and in relatively good condition. Over a six-month period, they engaged in a rigorous training program under supervision. The intensive
Esperanto
in
Cure Parkinson's
3 months ago
Buprenorphine transition from patch to tablets
Hey Everyone With the help of a 20 mg 7 day Buprenorphine patch, I have been free of any dopamine agonist for almost 3 months. But as we all know, the patch does not last 7 days, 5 if you are lucky. Consequently, I change it every 5 days and have had pretty good results. Initially, I would have moderate
Hey Everyone With the help of a 20 mg 7 day Buprenorphine patch, I have been free of any dopamine agonist for almost 3 months. But as we all know, the patch does not last 7 days, 5 if you are lucky. Consequently, I change it every 5 days and have had pretty good results. Initially, I would have moderate
RiversW
in
Restless Legs Syndrome
3 months ago
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