Search
Search
About
Log in
Join
Experiences with
Depakine
Posts
Communities
1,966 public posts
Filter results
‘World's 1st' fetal brain stem cell transplant effective in Parkinson's disease: study
CHA University Bundang Medical Center (CBMC) said on Monday that its researchers proved the safety and effectiveness of dopamine neural precursor cells derived from fetal mesenchymal stem cells transplanted into patients with Parkinson's disease "for the first time in the world." Cell replacement therapy
CHA University Bundang Medical Center (CBMC) said on Monday that its researchers proved the safety and effectiveness of dopamine neural precursor cells derived from fetal mesenchymal stem cells transplanted into patients with Parkinson's disease "for the first time in the world." Cell replacement therapy
Baron1
in
Cure Parkinson's
1 year ago
Using L-Tyrosine with Fluoxetine (Prozac)?
hello new member here. I’ve recently been prescribed Fluoxetine 20mg and was just wondering if it’s fine to take with 500mg L-Tyrosine thanks? After doing a bit of research it seems Fluoxetine increases serotonin levels in the brain but does absolutely nothing for Dopamine levels which is why I would
hello new member here. I’ve recently been prescribed Fluoxetine 20mg and was just wondering if it’s fine to take with 500mg L-Tyrosine thanks? After doing a bit of research it seems Fluoxetine increases serotonin levels in the brain but does absolutely nothing for Dopamine levels which is why I would
DP199777
in
Anxiety and Depression Support
1 year ago
has anyone heard of Brillia and S100B protein?
I was reading about this in the ADHD community. Sounds interesting. I think there is some crossover with ADHD and Parkinson’s symptoms https://en.wikipedia.org/wiki/S100B https://pubmed.ncbi.nlm.nih.gov/33052436/ “The exact etiology of Parkinson's disease (PD) remains obscure, lacking effective diagnostic
I was reading about this in the ADHD community. Sounds interesting. I think there is some crossover with ADHD and Parkinson’s symptoms https://en.wikipedia.org/wiki/S100B https://pubmed.ncbi.nlm.nih.gov/33052436/ “The exact etiology of Parkinson's disease (PD) remains obscure, lacking effective diagnostic
LAJ12345
in
Cure Parkinson's
1 year ago
Want to take advantage of all our features? Just log in!
Log in
or
Join
Mayo dopamine agonists withdrawal procedure
Hi everyone, any comment on below? "Discontinuation of dopamine agonists because of severe augmentation or other adverse effects and substitution of a drug of a different class (such as an alpha2-delta ligand) can be achieved in 2 ways. The initial drug can be reduced slowly after the new agent
Hi everyone, any comment on below? "Discontinuation of dopamine agonists because of severe augmentation or other adverse effects and substitution of a drug of a different class (such as an alpha2-delta ligand) can be achieved in 2 ways. The initial drug can be reduced slowly after the new agent
rls-ottawa
in
Restless Legs Syndrome
1 year ago
ChatGPT and Restless legs
many. of us now use ChatGPT to answer any questions we might. have. I asked ChatGPT about restless leg syndrome. Below are the answers. How do you deal with a severe case of a patient with restless leg syndrome? How can you help them with the discomfort and sleepless nights? 1. Use medication
many. of us now use ChatGPT to answer any questions we might. have. I asked ChatGPT about restless leg syndrome. Below are the answers. How do you deal with a severe case of a patient with restless leg syndrome? How can you help them with the discomfort and sleepless nights? 1. Use medication
thorp
in
Restless Legs Syndrome
1 year ago
Cholesterol-lowering drug aids mitochondria in Parkinson’s models
https://parkinsonsnewstoday.com/news/cholesterol-drug-aids-mitochondria-parkinsons-models/ Probucol, no longer in wide use, may open new way of treating disease by Marisa Wexler, MS | March 7, 2023 Probucol, a cholesterol-lowering medication previously used in Western countries, improved motor function
https://parkinsonsnewstoday.com/news/cholesterol-drug-aids-mitochondria-parkinsons-models/ Probucol, no longer in wide use, may open new way of treating disease by Marisa Wexler, MS | March 7, 2023 Probucol, a cholesterol-lowering medication previously used in Western countries, improved motor function
Sun_and_flowers
in
Cure Parkinson's
1 year ago
Thought I was figuring things out...
I had to move my psychiatric care to the VA, after so much difficulty with Moda and then Kaiser. I had been diagnosed with ADHD at the age of 47 (now 48) by a MD psychiatrist. The VA set me up with a psychiatric mental health nurse practitioner over telehealth. On our first visit, the NP said to me
I had to move my psychiatric care to the VA, after so much difficulty with Moda and then Kaiser. I had been diagnosed with ADHD at the age of 47 (now 48) by a MD psychiatrist. The VA set me up with a psychiatric mental health nurse practitioner over telehealth. On our first visit, the NP said to me
HumbledByNature
in
CHADD's Adult ADHD Support
1 year ago
Phellodendron - MAO-B - Dopamine - Relora
I was thumbing through the Feb LEF mag & noticed that phellodendron tree bark was being touted as an inhibitor of monoamine oxidase B (MAO-B). MAO-B is an enzyme which breaks down dopamine. Our levels of the 'feel-good' neurotransmitter decline about 13% per decade after age 45. MAO-B is also a target
I was thumbing through the Feb LEF mag & noticed that phellodendron tree bark was being touted as an inhibitor of monoamine oxidase B (MAO-B). MAO-B is an enzyme which breaks down dopamine. Our levels of the 'feel-good' neurotransmitter decline about 13% per decade after age 45. MAO-B is also a target
pjoshea13
in
Fight Prostate Cancer
1 year ago
Insulin Resistance, Parkinson's Disease, Consequences And What To Do About It
The topic of insulin resistance (IR) in PwP is not often discussed. Has your MDS or neurologist ever tested you for IR? It is estimated that two thirds of people with PD who are not diabetic, have IR and very likely are not even aware they have IR as discussed here : https://www.parkinson.org/blog/
The topic of insulin resistance (IR) in PwP is not often discussed. Has your MDS or neurologist ever tested you for IR? It is estimated that two thirds of people with PD who are not diabetic, have IR and very likely are not even aware they have IR as discussed here : https://www.parkinson.org/blog/
chartist
in
Cure Parkinson's
1 year ago
What does GPT4 have to say about the role of inflammation in RLS?
GPT4 is the latest release of a language based artificial intelligence program and I asked it what role did systemic inflammation have in RLS. This was the answer I got: "Chronic inflammation can contribute to the dysfunction of the dopamine system by damaging the dopaminergic neurons in the brain
GPT4 is the latest release of a language based artificial intelligence program and I asked it what role did systemic inflammation have in RLS. This was the answer I got: "Chronic inflammation can contribute to the dysfunction of the dopamine system by damaging the dopaminergic neurons in the brain
Eryl
in
Restless Legs Syndrome
1 year ago
Placebo vs Nocebo
Everyone knows about placebo; You take a medication and feel better but the medication is a sugar pill. Nocebo is the opposite side of the coin; I feel worse after a trip to the doctor. I feel worse because he asks whether I have stiffness or bradykinesia or balance problems or tremor or
Everyone knows about placebo; You take a medication and feel better but the medication is a sugar pill. Nocebo is the opposite side of the coin; I feel worse after a trip to the doctor. I feel worse because he asks whether I have stiffness or bradykinesia or balance problems or tremor or
kaypeeoh
in
Cure Parkinson's
1 year ago
Parkinsons? Or not?
My husband Peter has had a cervical spinal cord injury for 11 years now. This badly affects his mobility, upper body and hand function. He suffers from spasticity and very tight muscles. He can walk with aids but uses a wheelchair outdoors. Some months ago he started getting dizziness/lightheadedness
My husband Peter has had a cervical spinal cord injury for 11 years now. This badly affects his mobility, upper body and hand function. He suffers from spasticity and very tight muscles. He can walk with aids but uses a wheelchair outdoors. Some months ago he started getting dizziness/lightheadedness
Mo51
in
Cure Parkinson's
1 year ago
Curcumin Update 2023/03/06
I'm trying to get more organized so any post on a topic will include everything relevant to that topic in one post. So, for instance, future curcumin posts will be updates of this post:
Curcumin Update 2023/03/06
Last Updated:
2023/03/06 [u]
Status: In my stack as of 2023/03/05[/b
I'm trying to get more organized so any post on a topic will include everything relevant to that topic in one post. So, for instance, future curcumin posts will be updates of this post:
Curcumin Update 2023/03/06
Last Updated:
2023/03/06 [u]
Status: In my stack as of 2023/03/05[/b
Bolt_Upright
in
Cure Parkinson's
1 year ago
Long-term treatment with transcranial pulsed electromagnetic fields improves movement speed and elevates cerebrospinal erythropoietin in PD
Long-term treatment with [u]
transcranial
[/u] pulsed electromagnetic fields improves movement speed and elevates cerebrospinal erythropoietin in Parkinson’s disease https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8081215/
Background
Parkinson’s disease is characterized by motor dysfunctions
Long-term treatment with [u]
transcranial
[/u] pulsed electromagnetic fields improves movement speed and elevates cerebrospinal erythropoietin in Parkinson’s disease https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8081215/
Background
Parkinson’s disease is characterized by motor dysfunctions
Bolt_Upright
in
Cure Parkinson's
1 year ago
First patient receives milestone stem cell-based transplant for Parkinson Disease at Lund University, Sweden.
https://www.lunduniversity.lu.se/article/first-patient-receives-milestone-stem-cell-based-transplant-parkinsons-disease On 13th of February, a transplant of stem cell-derived nerve cells was administered to a person with Parkinson’s at Skåne University Hospital, Sweden. The product has been developed
https://www.lunduniversity.lu.se/article/first-patient-receives-milestone-stem-cell-based-transplant-parkinsons-disease On 13th of February, a transplant of stem cell-derived nerve cells was administered to a person with Parkinson’s at Skåne University Hospital, Sweden. The product has been developed
Hidden
in
Cure Parkinson's
1 year ago
Magnesium and dopamine
Maybe someone can help explain the effect of magnesium on dopamine levels.I thought a dopamine agonist was helpful in calming rls. Magnesium is an antagonist so decreases dopamine levels, yet is touted as effective in controlling rls. Don't know if I'm making any sense here. I also read that taking mg
Maybe someone can help explain the effect of magnesium on dopamine levels.I thought a dopamine agonist was helpful in calming rls. Magnesium is an antagonist so decreases dopamine levels, yet is touted as effective in controlling rls. Don't know if I'm making any sense here. I also read that taking mg
rmbroadh
in
Restless Legs Syndrome
1 year ago
THC and augmentation
In researching THC use and RLS, it is described as a dopamine agonist. Is there evidence it can also produce augmentation? . It works very well for me and does not produce the side effect that makes Gabapentin, Lyrica or opioids unacceptable options. However I can’t use it much because of my line of
In researching THC use and RLS, it is described as a dopamine agonist. Is there evidence it can also produce augmentation? . It works very well for me and does not produce the side effect that makes Gabapentin, Lyrica or opioids unacceptable options. However I can’t use it much because of my line of
Hidden
in
Restless Legs Syndrome
1 year ago
Pramipexole to Sinemet to ?
I've previously posted that I had been using pramipexole (P) for over 30 years, had only learned about augmentation recently and was in the process of transitioning off P to Sinemet (S)(recommended by my PCP). The transition went very well, however, an allergic reaction to S (a rash developed) made
I've previously posted that I had been using pramipexole (P) for over 30 years, had only learned about augmentation recently and was in the process of transitioning off P to Sinemet (S)(recommended by my PCP). The transition went very well, however, an allergic reaction to S (a rash developed) made
robertff3401
in
Restless Legs Syndrome
1 year ago
Seratonin for resting tremor : could tremor that doesn’t respond to just dopamine need more seratonin?
pharmacological treatment for tremor that acts on serotonin to recover dopamine levels. This latter result has been validated by reproducing existing data collected with human patients. PD resting tremor can be divided into various partially overlapping phenotypes that may be associated with different
pharmacological treatment for tremor that acts on serotonin to recover dopamine levels. This latter result has been validated by reproducing existing data collected with human patients. PD resting tremor can be divided into various partially overlapping phenotypes that may be associated with different
Little_apple
in
Cure Parkinson's
1 year ago
Vagal Nerve Stimulation (tVNS) Research Summary
Some definitions for clarity. Neuromodulation, stimulating nerves (usually with electricity) to change (hopefully improve) or control their function. Deep Brain Stimulation (DBS) is a form of neuromodulation. Neuromodulation can be invasive, requiring surgery (like DBS) or noninvasive which provides
Some definitions for clarity. Neuromodulation, stimulating nerves (usually with electricity) to change (hopefully improve) or control their function. Deep Brain Stimulation (DBS) is a form of neuromodulation. Neuromodulation can be invasive, requiring surgery (like DBS) or noninvasive which provides
House2
in
Cure Parkinson's
1 year ago
1
...
16
17
18
...
99
Next page
10
20
30
40
50
60
70
80
90
Filter results
Clear filters
Posted in
All communities
Cure Parkinson's
1005 results
Restless Legs Syndrome
582 results
CHADD's Adult ADHD Support
55 results
View top 10 communities
Sort by
Most Relevant
Newest