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US FDA declines to approve Supernus' Parkinson's combination again
The company plans to address the FDA's concerns and resubmit its application for the product, which aims to treat so-called "off episodes", which affects nearly all patients of Parkinson's, heightening symptoms such as tremors and difficulty in walking, as medication wears off. https://www.reuters.com
The company plans to address the FDA's concerns and resubmit its application for the product, which aims to treat so-called "off episodes", which affects nearly all patients of Parkinson's, heightening symptoms such as tremors and difficulty in walking, as medication wears off. https://www.reuters.com
Farooqji
in
Cure Parkinson's
3 months ago
Protein discovery could help solve prostate cancer drug resistance Date:January 22, 2024 Source:Washington State University
I found this information while researching my husband's PSA rising issues. Found it interesting and want to share. Click on link to read the entire article https://www.sciencedaily.com/ Protein discovery could help solve prostate cancer drug resistance Date: January 22, 2024 Source: Washington
I found this information while researching my husband's PSA rising issues. Found it interesting and want to share. Click on link to read the entire article https://www.sciencedaily.com/ Protein discovery could help solve prostate cancer drug resistance Date: January 22, 2024 Source: Washington
MsHope
in
Advanced Prostate Cancer
3 months ago
child low cortisol
Hi, I would be very grateful for any advice etc on the following. My 9 year old daughter has had a blood test come back with borderline low cortisone ( that’s what the doctor has described it as). She is waiting for a test but apparently it can take months. The doctor has mentioned Addisons and under
Hi, I would be very grateful for any advice etc on the following. My 9 year old daughter has had a blood test come back with borderline low cortisone ( that’s what the doctor has described it as). She is waiting for a test but apparently it can take months. The doctor has mentioned Addisons and under
Karatesarah
in
Thyroid UK
3 months ago
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Fibroscan result waiting time?
Please can somebody tell me how long it takes to receive results for a fibroscan? I started this journey in November 2023 after asking for a general check-up at my GP surgery because of some non-liver related issues. I had no awareness at all that my liver could be damaged. After a few rounds of blood
Please can somebody tell me how long it takes to receive results for a fibroscan? I started this journey in November 2023 after asking for a general check-up at my GP surgery because of some non-liver related issues. I had no awareness at all that my liver could be damaged. After a few rounds of blood
Trotter2024
in
British Liver Trust
3 months ago
Help with Cortisol test
Hello all, I had a saliva cortisol test done last week. Ive got the results back but with no comments from the clinic. They look okay/normal to me? Apart from the 3rd one? I was expecting them to be low as I thought I was suffering from adrenal fatigue. Could anyone advise me on these levels?
Hello all, I had a saliva cortisol test done last week. Ive got the results back but with no comments from the clinic. They look okay/normal to me? Apart from the 3rd one? I was expecting them to be low as I thought I was suffering from adrenal fatigue. Could anyone advise me on these levels?
Dahliasanddaisies
in
Thyroid UK
3 months ago
Urolithin A (UA) – To anybody taking, what’s your experience?
Sometimes, I feel gullible for the fleeing by an over-priced, over-hyped supplement. As I understand, UA is produced by bacteria in your gut and without the right bacteria, your gut can’t produce from food. And, maybe the product is more concentrated than what’s produced by bacteria. AI Says: “Urolithin
Sometimes, I feel gullible for the fleeing by an over-priced, over-hyped supplement. As I understand, UA is produced by bacteria in your gut and without the right bacteria, your gut can’t produce from food. And, maybe the product is more concentrated than what’s produced by bacteria. AI Says: “Urolithin
Gcf51
in
Cure Parkinson's
3 months ago
How about eating a healthy snack that might help fight PCa. Lotus seeds (Nelumbo nucifera) also known as makhana contain Neferine, see below
Neferine inhibits proliferation and migration of human prostate cancer stem cells through p38 MAPK/JNK activation Suat Erdogan, Kader Turkekul First published: 11 May 2020 https://doi.org/10.1111/jfbc.13253 Abstract Cancer stem cells (CSCs) are one of the significant causes of cancer treatment failure
Neferine inhibits proliferation and migration of human prostate cancer stem cells through p38 MAPK/JNK activation Suat Erdogan, Kader Turkekul First published: 11 May 2020 https://doi.org/10.1111/jfbc.13253 Abstract Cancer stem cells (CSCs) are one of the significant causes of cancer treatment failure
Graham49
in
Advanced Prostate Cancer
3 months ago
shrinking lung syndrome
Has anyone else been diagnosed with a rare condition called shrinking lung syndrome. It’s so rare, approximately only 0.5-1.1 % people with Lupus get it. I’m real scared as at time I feel like I’m slowly suffocating! Still getting more tests done to see if diaphragm isn’t partially paralyzed. Did you
Has anyone else been diagnosed with a rare condition called shrinking lung syndrome. It’s so rare, approximately only 0.5-1.1 % people with Lupus get it. I’m real scared as at time I feel like I’m slowly suffocating! Still getting more tests done to see if diaphragm isn’t partially paralyzed. Did you
hihannula
in
LUpus Patients Understanding and Support
3 months ago
Is anyone familiar with the GUN trial?
Hello, sorry for all the questions. My 59 year old husband was recently diagnosed and we have so much information coming at us, fast and furious. Yesterday he was offered an opportunity to participate in the GUN trial. So far the information we have about his cancer: CT scan inadvertently found the
Hello, sorry for all the questions. My 59 year old husband was recently diagnosed and we have so much information coming at us, fast and furious. Yesterday he was offered an opportunity to participate in the GUN trial. So far the information we have about his cancer: CT scan inadvertently found the
EvFC
in
Advanced Prostate Cancer
3 months ago
6 months post stent
Hi Guys,It's 6 months post LAD stent and I thought I would log my progress. My life is pretty much back to normal, work full time and busy as ever Fitness wise, running, cycling and walking but still not really pushing myself to the limit as I used to when racing as I thought I would give it a year
Hi Guys,It's 6 months post LAD stent and I thought I would log my progress. My life is pretty much back to normal, work full time and busy as ever Fitness wise, running, cycling and walking but still not really pushing myself to the limit as I used to when racing as I thought I would give it a year
Hidden
in
British Heart Foundation
5 months ago
Help. Icu
Hi all I'm new here but I'm also lost and don't know what to do. My mom currently needs a liver transplant but she has pneumonia and they had her sedated now she's awake but won't listen to orders.
Hi all I'm new here but I'm also lost and don't know what to do. My mom currently needs a liver transplant but she has pneumonia and they had her sedated now she's awake but won't listen to orders.
Joccelyn
in
ICUsteps
3 months ago
Should I stop aspirin before non cardiac surgery.
I am a 62 year old male and suffered a heart attack in Feb 2020. I subsequently had one stent fitted. I have been on low dose aspirin and other meds since then. I have not needed any further treatment and was told by the cardiac doctor that he wouldn't need to see me for another 5 years. I am due to
I am a 62 year old male and suffered a heart attack in Feb 2020. I subsequently had one stent fitted. I have been on low dose aspirin and other meds since then. I have not needed any further treatment and was told by the cardiac doctor that he wouldn't need to see me for another 5 years. I am due to
Deluge
in
British Heart Foundation
5 months ago
Bad news: prostate cancers doubling by 2040
Bad news on one side, for all the guys that will join the damn club (and the trends say their age is lowering as well....I am an example actually!). On the other side we can hope for an increase of effort to solve the problem, at least for prostate, breast, lung and colorectal cancers, which are quite
Bad news on one side, for all the guys that will join the damn club (and the trends say their age is lowering as well....I am an example actually!). On the other side we can hope for an increase of effort to solve the problem, at least for prostate, breast, lung and colorectal cancers, which are quite
Maxone73
in
Advanced Prostate Cancer
3 months ago
Expanded label sought for 177Lu-PSMA-617 in prostate cancer: about time
I have already done the taxane part and I would like to see how 177Lu performs as first line...but this is also interesting, it seems more effective than a change in ARPI in castration resistant setting "Data also showed that a PSA decline of at least 50% was more than 2.5 times more frequent with 177Lu-PSMA
I have already done the taxane part and I would like to see how 177Lu performs as first line...but this is also interesting, it seems more effective than a change in ARPI in castration resistant setting "Data also showed that a PSA decline of at least 50% was more than 2.5 times more frequent with 177Lu-PSMA
Maxone73
in
Advanced Prostate Cancer
3 months ago
Spirulina and Chlorella
Hi, i was diagnosed with Rheumatoid arthritis 5 years ago and I'm on methotrexate and hydroxycloroquine. I'm was hoping to start taking spirulina and chlorella as they have so many health benefits but I not sure of any drug interactions. I've tried Google but I'm getting conflicting advice, some say
Hi, i was diagnosed with Rheumatoid arthritis 5 years ago and I'm on methotrexate and hydroxycloroquine. I'm was hoping to start taking spirulina and chlorella as they have so many health benefits but I not sure of any drug interactions. I've tried Google but I'm getting conflicting advice, some say
Maple1981
in
NRAS
3 months ago
Next NoSilverBullet webinar on 22nd of April: Dr M Sexton on “How can medical cannabis help people with Parkinson’s?”
I am delighted to announce that our next NoSilverBullet Zoom webinar will be taking place at 7.30pm London time on Monday, the 22nd of April. Dr Michelle Sexton will be talking to us about “How can medical cannabis help people with Parkinson’s?” Please use the Eventbrite link below to register for
I am delighted to announce that our next NoSilverBullet Zoom webinar will be taking place at 7.30pm London time on Monday, the 22nd of April. Dr Michelle Sexton will be talking to us about “How can medical cannabis help people with Parkinson’s?” Please use the Eventbrite link below to register for
Michel0220
in
Cure Parkinson's
3 months ago
Angina at rest
I am very new to this forum so I would first like to say thank you for accepting me and to say how much I have picked up from reading some of the topics raised in my short time I have been pondering a question to the side that even my cardiologist can’t get to the bottom of but i hope someone in
I am very new to this forum so I would first like to say thank you for accepting me and to say how much I have picked up from reading some of the topics raised in my short time I have been pondering a question to the side that even my cardiologist can’t get to the bottom of but i hope someone in
Toffodog
in
British Heart Foundation
5 months ago
Severe Proximal RCA Disease and Moderate LAD Disease - NO FURTHER ACTION!
Hi - I had a call from the cardiologist this afternoon, after a team consultation they have decided they will not be performing an angiogram and hence I will not be receiving any stents. They have said a stent would not decrease my chances of having a heart attack, and therefore it's not worth the risk
Hi - I had a call from the cardiologist this afternoon, after a team consultation they have decided they will not be performing an angiogram and hence I will not be receiving any stents. They have said a stent would not decrease my chances of having a heart attack, and therefore it's not worth the risk
Segovia123
in
British Heart Foundation
5 months ago
Update May 15, 2024
Hoping all is well with others on this site. UPDATE May 15 2024 I am concerned about results of the Right frontal skull SUV 5.3 previously 0.75. I have researched and really can't find any information that I can understand. Any replies would be greatly appreciated My husband had his PSMA PET/
Hoping all is well with others on this site. UPDATE May 15 2024 I am concerned about results of the Right frontal skull SUV 5.3 previously 0.75. I have researched and really can't find any information that I can understand. Any replies would be greatly appreciated My husband had his PSMA PET/
MsHope
in
Advanced Prostate Cancer
3 months ago
poo activity post HA
I had a HA and stent operation 3 weeks ago today and my bowel movements have yet to return to any sort of normality. Embarrassing to share, but I have loose stools that are not painful but nearly every morning after taking lansoprazole or say 20 mins after my breakfast. Anyone remember if this
I had a HA and stent operation 3 weeks ago today and my bowel movements have yet to return to any sort of normality. Embarrassing to share, but I have loose stools that are not painful but nearly every morning after taking lansoprazole or say 20 mins after my breakfast. Anyone remember if this
30min-ambition
in
British Heart Foundation
5 months ago
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