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Addition of an ARSI to standard ADT significantly increases the risk of fractures and falls in men with prostate cancer
Jones C, Gray S, Brown M, et al. Risk of fractures and falls in men with advanced or metastatic prostate cancer receiving androgen deprivation therapy and treated with novel androgen receptor signalling inhibitors: a systematic review and meta-analysis of randomised controlled trials. Eur Urol Oncol.
Jones C, Gray S, Brown M, et al. Risk of fractures and falls in men with advanced or metastatic prostate cancer receiving androgen deprivation therapy and treated with novel androgen receptor signalling inhibitors: a systematic review and meta-analysis of randomised controlled trials. Eur Urol Oncol.
Graham49
in
Advanced Prostate Cancer
3 months ago
Cortisol test result
Hi, I have just had some blood test results come back today. Currently on 5.5mg, but have been taking 6mg (Sat 30th..Sun, Mon, Tues) as have had lots going on, bit stressful but good stress not bad! the 0.5mg did help. All results are ok including PV, ESR, CRP. Also had a basal cortisol test (partially
Hi, I have just had some blood test results come back today. Currently on 5.5mg, but have been taking 6mg (Sat 30th..Sun, Mon, Tues) as have had lots going on, bit stressful but good stress not bad! the 0.5mg did help. All results are ok including PV, ESR, CRP. Also had a basal cortisol test (partially
Saffron23
in
PMRGCAuk
3 months ago
'Wednesday Word"
Since my question yesterday was concerning 'brain fog', I thought my word for today should be [u][i]
encephalopathy
[/i][/u] - here are specifics about the word This is a blanket term referring to any brain dysfunction. It can commonly be called 'brain fog'. However, [u][i]
encephalopathy
Since my question yesterday was concerning 'brain fog', I thought my word for today should be [u][i]
encephalopathy
[/i][/u] - here are specifics about the word This is a blanket term referring to any brain dysfunction. It can commonly be called 'brain fog'. However, [u][i]
encephalopathy
DonnaBoll
Administrator
in
PBC Foundation
3 months ago
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PSA after chemo # 4
Hi My husbands last chemo was # 3 and PSA was 0.14, he just got the results from Chemo # 4 and it was at 0.12. This is the slowest decline if you look in the profile Iisted all his PSA results. Should we be worried that this last one barely moved ? Or is this slower decline good news? Thanks for any
Hi My husbands last chemo was # 3 and PSA was 0.14, he just got the results from Chemo # 4 and it was at 0.12. This is the slowest decline if you look in the profile Iisted all his PSA results. Should we be worried that this last one barely moved ? Or is this slower decline good news? Thanks for any
positive-thinking
in
Advanced Prostate Cancer
3 months ago
How Much Carbidopa Levodopa After 5-10 Years? Any other meds?
I am about to "celebrate" the six year anniversary of my Parkinson's disease diagnosis. I currently take five 25/100 Carbidopa Levodopa tablets per day, usually around 9:00 a.m., noon, 3:00 p.m., 6:00 p.m., and 9:00 p.m. although timing varies slightly from day to day. Lately, I have noticed that I
I am about to "celebrate" the six year anniversary of my Parkinson's disease diagnosis. I currently take five 25/100 Carbidopa Levodopa tablets per day, usually around 9:00 a.m., noon, 3:00 p.m., 6:00 p.m., and 9:00 p.m. although timing varies slightly from day to day. Lately, I have noticed that I
jimcaster
in
Cure Parkinson's
3 months ago
clopidril
I have been on Clopidril since having 4 stents in 2015 then a by pass in my leg. I then had another stent fitted in 2022. Further investigations found narrowing of the arteries in my other leg. I believe the clopidril is causing the hot sweats I have been having for years. I am wondering whether I have
I have been on Clopidril since having 4 stents in 2015 then a by pass in my leg. I then had another stent fitted in 2022. Further investigations found narrowing of the arteries in my other leg. I believe the clopidril is causing the hot sweats I have been having for years. I am wondering whether I have
MaryBob
in
British Heart Foundation
5 months ago
Crohns/IBD
I have undiagnosed Crohns/IBD and continuous flares. I had surgery in 2011 resection of 20cm colon. What treatments are effective?
I have undiagnosed Crohns/IBD and continuous flares. I had surgery in 2011 resection of 20cm colon. What treatments are effective?
Lalande
in
Thyroid UK
3 months ago
Rising PCA - on ADT Holiday
Diagnosed Stage 4 oligometastatic (low volume) PCA in 2021. Gleason 7, 4+3 . Completed RT and 18 months on ADT (Nubeqa) paused the ADT in September after PSA non detectable and a fresh set of scans showed no “evidence of disease”. Continued to do bloodwork quarterly and PSA remained at 0. Until
Diagnosed Stage 4 oligometastatic (low volume) PCA in 2021. Gleason 7, 4+3 . Completed RT and 18 months on ADT (Nubeqa) paused the ADT in September after PSA non detectable and a fresh set of scans showed no “evidence of disease”. Continued to do bloodwork quarterly and PSA remained at 0. Until
Kkash
in
Advanced Prostate Cancer
3 months ago
Travel insurance
Hi ,I have had a blocked coronary artery and a stent fitted. I also have atrial fibrillation. Can anyone recommend reasonable travel insurance companies ?thanks in advance
Hi ,I have had a blocked coronary artery and a stent fitted. I also have atrial fibrillation. Can anyone recommend reasonable travel insurance companies ?thanks in advance
BRMBRM1970
in
British Heart Foundation
5 months ago
still getting angina
in Sept, 2023 I had a pacemaker fitted. Angiogram showed I had the start of plaque in 2 arteries, but not enough for a stent. cardiologist said that I am fine, but I am still struggling with my breathing, especially uphill. Last week I walked for an hour up a downhill and it took me 24 hours to recover
in Sept, 2023 I had a pacemaker fitted. Angiogram showed I had the start of plaque in 2 arteries, but not enough for a stent. cardiologist said that I am fine, but I am still struggling with my breathing, especially uphill. Last week I walked for an hour up a downhill and it took me 24 hours to recover
BlueTosca
in
British Heart Foundation
5 months ago
Confused
UPDATE: April 5, 2024 Yesterday was very disappointing as my husbands PSA increased again by 183 points, last month his PSA was 1546 and now it is 1730. All his other CBC results were good. His Alkaline Phosphatase increased 6 points, last month 127 and now 133 but still in range of 40-150. Questioned
UPDATE: April 5, 2024 Yesterday was very disappointing as my husbands PSA increased again by 183 points, last month his PSA was 1546 and now it is 1730. All his other CBC results were good. His Alkaline Phosphatase increased 6 points, last month 127 and now 133 but still in range of 40-150. Questioned
MsHope
in
Advanced Prostate Cancer
3 months ago
Psa level
Just came off degarlix as psa level was rising, now on xtadi apalutamide how long does it take for psa level to fall and by how much?
Just came off degarlix as psa level was rising, now on xtadi apalutamide how long does it take for psa level to fall and by how much?
littlemount
in
Advanced Prostate Cancer
3 months ago
fibroscan score 7.9 f1 finrosis
I don’t understand this report as 7.9 Kos should indicate f2 fibrosis not f1 also the did not give me a cap score Not overweight very fit active no alcohol or any kind of hepatitis not hereditary conditions either So quite confused
I don’t understand this report as 7.9 Kos should indicate f2 fibrosis not f1 also the did not give me a cap score Not overweight very fit active no alcohol or any kind of hepatitis not hereditary conditions either So quite confused
TacosPizzaIcecream
in
British Liver Trust
3 months ago
My gfr is om 15 % already but I dont want dialysis
Hi everyone happy Easter, hope everyone is well so I'm already at 15 % gfr and so worried I do want to get in dialysis I want to go straight to the transplants . I when to recently get blood work at my gyno and it should my gfr 15 % but I have a cold and was a bit dehydrated since I drank k 2 bottle
Hi everyone happy Easter, hope everyone is well so I'm already at 15 % gfr and so worried I do want to get in dialysis I want to go straight to the transplants . I when to recently get blood work at my gyno and it should my gfr 15 % but I have a cold and was a bit dehydrated since I drank k 2 bottle
jennifer24
in
Early CKD Support
3 months ago
Long term Effects of radiation
I had salvage radiation in 2014 after failed RP surgery in 2013 at age 69 for Gleason 9 PCa. I’ve also had radiation of pelvic lymph nodes in 2015 , right femur in 2017, and a rib and clavicle in 2018. A few years ago incontinence developed. I tried clamp, sling and AUS. The latter caused sepsis
I had salvage radiation in 2014 after failed RP surgery in 2013 at age 69 for Gleason 9 PCa. I’ve also had radiation of pelvic lymph nodes in 2015 , right femur in 2017, and a rib and clavicle in 2018. A few years ago incontinence developed. I tried clamp, sling and AUS. The latter caused sepsis
Break60
in
Advanced Prostate Cancer
5 months ago
Prostrate Removed, PSA increasing
Hello to all, Is there anyone who had their prostrate removed but PSA is increasing? Oncologist wants to try a new hormonal drug. Radiation was administered after surgery. PSA is increasing. We appreciate your feedback. P.S. Edited profile: “Last CAT Scan was November 2023 - Showed no metastases
Hello to all, Is there anyone who had their prostrate removed but PSA is increasing? Oncologist wants to try a new hormonal drug. Radiation was administered after surgery. PSA is increasing. We appreciate your feedback. P.S. Edited profile: “Last CAT Scan was November 2023 - Showed no metastases
BlessedParchy
in
Advanced Prostate Cancer
3 months ago
Is Jevtana easier to tolerate than docetaxel?
I have noticed that some men on this site have had over 30 infusions of Jevtana. My husband has had completed 10 sessions of docetaxel. The last three were given with a second dose of Carboplatin. Jevtana is new to us. How is it tolerated? Why can it be given at such a high number of doses?
I have noticed that some men on this site have had over 30 infusions of Jevtana. My husband has had completed 10 sessions of docetaxel. The last three were given with a second dose of Carboplatin. Jevtana is new to us. How is it tolerated? Why can it be given at such a high number of doses?
roboocme
in
Advanced Prostate Cancer
3 months ago
IMRT WITHOUT THE JELL
I'm scheduled for IMRT Radistion without the jell. Doc says the jell may push cancer microscopic cells away from the prostate. He said the cancer is about to protrude through the capsule and microsopic cancer cells could be out of the capsule and did not want to take a chance of putting the jell in and
I'm scheduled for IMRT Radistion without the jell. Doc says the jell may push cancer microscopic cells away from the prostate. He said the cancer is about to protrude through the capsule and microsopic cancer cells could be out of the capsule and did not want to take a chance of putting the jell in and
woppaginny
in
Advanced Prostate Cancer
3 months ago
Husband with PSP
Hi there My husband was 80 last week also diagnosed with Psp after an initial diagnosis of Parkinson’s He is Madopar four times a day plus to Amantandine the medication has helped a lot with his tremor His mobility is very poor, he had another fall today. The lack of empathy is very common and
Hi there My husband was 80 last week also diagnosed with Psp after an initial diagnosis of Parkinson’s He is Madopar four times a day plus to Amantandine the medication has helped a lot with his tremor His mobility is very poor, he had another fall today. The lack of empathy is very common and
Poodlelady1
in
PSP Association
3 months ago
Cat's Claw
Anyone out there know of taking Cat's Claw tiincture for Parkinson's shake ( tremor)? Anyother benefit?
Anyone out there know of taking Cat's Claw tiincture for Parkinson's shake ( tremor)? Anyother benefit?
b-bobble
in
Cure Parkinson's
3 months ago
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