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is this what CR looks like?
Starting Nov 20 last year, I began a relugolix on-cycle. Here’s the PSA readings from that point: Nov 20 : 3.10 Jan 8: 0.31 Feb 27: 0.13 Apr 15: 0.08 So up to this point, the PSA is dropping nicely, as it always has with on-cycles; and as I would expect, since I’ve been a strong responder
Starting Nov 20 last year, I began a relugolix on-cycle. Here’s the PSA readings from that point: Nov 20 : 3.10 Jan 8: 0.31 Feb 27: 0.13 Apr 15: 0.08 So up to this point, the PSA is dropping nicely, as it always has with on-cycles; and as I would expect, since I’ve been a strong responder
lokibear0803
in
Advanced Prostate Cancer
26 days ago
Egg Donor Transfer
Hi We have selected our egg donor!! We are using frozen eggs currently in the bank at our clinic. Well, they are in their UK branch and we are using a clinic in Dublin, so the the eggs need to be transported over. Prior to transferring, our clinic has recommended me having an Endo Trio test, which
Hi We have selected our egg donor!! We are using frozen eggs currently in the bank at our clinic. Well, they are in their UK branch and we are using a clinic in Dublin, so the the eggs need to be transported over. Prior to transferring, our clinic has recommended me having an Endo Trio test, which
Mrsjaytee
in
Fertility Network UK
5 months ago
Diuretics
I have pretty severe edema in feet and occasionally legs.Is there a diuretic that does not trigger rls? I have tried Bumex and Metolazone. Had very bad rls soon after taking each one. I am on low dose Ropinirole -.9mg . It didn't even calm it. Appreciate any input.
I have pretty severe edema in feet and occasionally legs.Is there a diuretic that does not trigger rls? I have tried Bumex and Metolazone. Had very bad rls soon after taking each one. I am on low dose Ropinirole -.9mg . It didn't even calm it. Appreciate any input.
rmbroadh
in
Restless Legs Syndrome
27 days ago
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Questions regarding dialysis and also transplant
Hi Everyone, Hope everyone is ok with all the crazy weather that has taken place all over. I recently started hemodialysis in the last week. Once again I have had to learn everything from you all or reading online/or in books which is not overly helpful at times. The dialysis center folks think my nephrologist
Hi Everyone, Hope everyone is ok with all the crazy weather that has taken place all over. I recently started hemodialysis in the last week. Once again I have had to learn everything from you all or reading online/or in books which is not overly helpful at times. The dialysis center folks think my nephrologist
Missingthesun
in
Kidney Dialysis
27 days ago
Erleada or Xtandi with Orgovyx, preference one way or the other?
Dx 2015 Gleason 7, prostatectomy 2015, seminal vessel invasion one side, fast forward 3 years recurrence and 39 sessions of radiation to prostate bed and back to PSA undetectable. Fast forward to fall of 2019 PSA back to 4.3 PSMA Pet scan shows iliac crest area met along with lymph nodes prostate bed
Dx 2015 Gleason 7, prostatectomy 2015, seminal vessel invasion one side, fast forward 3 years recurrence and 39 sessions of radiation to prostate bed and back to PSA undetectable. Fast forward to fall of 2019 PSA back to 4.3 PSMA Pet scan shows iliac crest area met along with lymph nodes prostate bed
Wynnsts
in
Advanced Prostate Cancer
28 days ago
Allopregnanolone as a Regenerative Treatment for Parkinson's Disease (Allo-PD)
I just happened upon this trial and it is something I had never heard of. It looks like a very small trial being conducted in Tucson, AZ. https://clinicaltrials.gov/study/NCT06263010?locStr=Arizona&country=United%20States&state=Arizona&cond=Parkinson%20disease&aggFilters=status:not%20rec&rank=2 Detailed
I just happened upon this trial and it is something I had never heard of. It looks like a very small trial being conducted in Tucson, AZ. https://clinicaltrials.gov/study/NCT06263010?locStr=Arizona&country=United%20States&state=Arizona&cond=Parkinson%20disease&aggFilters=status:not%20rec&rank=2 Detailed
Boscoejean
in
Cure Parkinson's
28 days ago
Rising PSA with little shown on PSMA PET
Greetings all. I've been on this forum for years. I've only commented a handful of times, and never made a post. I prefer to usually just read from the sidelines. First of all, a bit about my path thus far. I was diagnosed in May 2010 (age 49) (PSA 4.7 and Gleason 7), had radical surgery in July 2010
Greetings all. I've been on this forum for years. I've only commented a handful of times, and never made a post. I prefer to usually just read from the sidelines. First of all, a bit about my path thus far. I was diagnosed in May 2010 (age 49) (PSA 4.7 and Gleason 7), had radical surgery in July 2010
velobard
in
Advanced Prostate Cancer
28 days ago
Not PCa but related. Imuno therapies keeps getting better.
On April 4, 2024, Candel Therapeutics, Inc. (the “Company”) issued a press release announcing positive interim data from its randomized phase 2 clinical trial of CAN-2409 in non-metastatic pancreatic cancer. A copy of the full press release is attached as Exhibit 99.1 to this Current Report on Form
On April 4, 2024, Candel Therapeutics, Inc. (the “Company”) issued a press release announcing positive interim data from its randomized phase 2 clinical trial of CAN-2409 in non-metastatic pancreatic cancer. A copy of the full press release is attached as Exhibit 99.1 to this Current Report on Form
Scout4answers
in
Advanced Prostate Cancer
3 months ago
Next NoSilverBullet webinar on 17th of June: Sackner-Bernstein, MD, on "Why I am optimistic that we might now have a Silver Bullet for PD".
I am delighted to announce that our next NoSilverBullet Zoom webinar will be taking place at 7.30pm London time on Monday, the 17th of June. Jonathan Sackner-Bernstein, MD, will be talking to us about "Why I am optimistic that we might now have a Silver Bullet for PD". Please use the Eventbrite link
I am delighted to announce that our next NoSilverBullet Zoom webinar will be taking place at 7.30pm London time on Monday, the 17th of June. Jonathan Sackner-Bernstein, MD, will be talking to us about "Why I am optimistic that we might now have a Silver Bullet for PD". Please use the Eventbrite link
Michel0220
in
Cure Parkinson's
28 days ago
The 40 Hz flickering light restores synaptic plasticity and mitochondrial phenotype in experimental model of Alzheimer's disease May 2024
The 40 Hz flickering light restores synaptic plasticity and mitochondrial phenotype in experimental model of Alzheimer's disease May 2024
- https://www.researchgate.net/publication/380600451_The_40_Hz_flickering_light_restores_synaptic_plasticity_and_mitochondrial_phenotype_in_experimental_model_of_Alzheimer
The 40 Hz flickering light restores synaptic plasticity and mitochondrial phenotype in experimental model of Alzheimer's disease May 2024
- https://www.researchgate.net/publication/380600451_The_40_Hz_flickering_light_restores_synaptic_plasticity_and_mitochondrial_phenotype_in_experimental_model_of_Alzheimer
Bolt_Upright
in
Cure Parkinson's
28 days ago
what is the risk from ALA?
What is this community’s take on ALA, as found in flaxseed oil? Is there risk for prostate cancer? If there is “risk”, is that solely an association with increased PSA? i.e. do significant amounts of flaxseed oil cause a change only in one’s baseline PSA? i.e. does it promote the [i]
production[
What is this community’s take on ALA, as found in flaxseed oil? Is there risk for prostate cancer? If there is “risk”, is that solely an association with increased PSA? i.e. do significant amounts of flaxseed oil cause a change only in one’s baseline PSA? i.e. does it promote the [i]
production[
lokibear0803
in
Advanced Prostate Cancer
29 days ago
The role of PSMA PET/CT in predicting downgrading in patients with Gleason score 4+4 prostate cancer in prostate biopsy - W Jour Uro 5/21/24
[i]An interesting investigation aimed at validating the use of PSMA PET/CT in patients to adjust the Gleason score (downward) of their cancer based on conventional pre-surgery biopsy, scans (ultrasound & MRI). In this instance the focus was on downgrading from a high-risk of 8 to an intermediate-risk
[i]An interesting investigation aimed at validating the use of PSMA PET/CT in patients to adjust the Gleason score (downward) of their cancer based on conventional pre-surgery biopsy, scans (ultrasound & MRI). In this instance the focus was on downgrading from a high-risk of 8 to an intermediate-risk
cujoe
in
Fight Prostate Cancer
29 days ago
Any Carnivore dieters who are taking Parkinson’s medication?
Hello, I am a 42 year old woman, diagnosed with Parkinson’s, 17 years ago, at the age of 40. started Kinson Parkinson’s medication 4 years ago but I’m experiencing increased meds off times. I heard about the Carnivore diet and I am very interested in trying it, but I am not sure joe I can do it successfully
Hello, I am a 42 year old woman, diagnosed with Parkinson’s, 17 years ago, at the age of 40. started Kinson Parkinson’s medication 4 years ago but I’m experiencing increased meds off times. I heard about the Carnivore diet and I am very interested in trying it, but I am not sure joe I can do it successfully
Seekerofhealth
in
Cure Parkinson's
29 days ago
PCA Prognosis?
Hi All! I am due for my 4rd Lupron treatment and follow-up next week. My bloodwork is done and my PSA is still <.01 for 9 months now. I have BRCA 1 and 2. When my Urologist gave me my initial diagnosis after my biopsies (Gleason 4+3=7 and 11 of 12 biopsies positive). nHe gave me a full report
Hi All! I am due for my 4rd Lupron treatment and follow-up next week. My bloodwork is done and my PSA is still <.01 for 9 months now. I have BRCA 1 and 2. When my Urologist gave me my initial diagnosis after my biopsies (Gleason 4+3=7 and 11 of 12 biopsies positive). nHe gave me a full report
Sagewiz
in
Advanced Prostate Cancer
29 days ago
Enter our poster competition for World Lupus Day 2024!
This year we're launching a poster competition for our 2024 World Lupus Day campaign. The theme of the poster will be centred around those who have been newly diagnosed with lupus to coincide with the launch of our new information video on World Lupus Day! For more information on what the poster needs
This year we're launching a poster competition for our 2024 World Lupus Day campaign. The theme of the poster will be centred around those who have been newly diagnosed with lupus to coincide with the launch of our new information video on World Lupus Day! For more information on what the poster needs
Debbie_kinsey
Administrator
in
LUPUS UK
6 months ago
Two updates in the Guidelines for PBC
PRACTICE GUIDANCE Primary biliary cholangitis: 2021 practice guidance update from the American Association for the Study of Liver Diseases Lindor, Keith D.*,1; Bowlus, Christopher L.2; Boyer, James3; Levy, Cynthia4; Mayo, Marlyn5 Author Information Hepatology 75(4):p 1012-1013, April 2022. | DOI
PRACTICE GUIDANCE Primary biliary cholangitis: 2021 practice guidance update from the American Association for the Study of Liver Diseases Lindor, Keith D.*,1; Bowlus, Christopher L.2; Boyer, James3; Levy, Cynthia4; Mayo, Marlyn5 Author Information Hepatology 75(4):p 1012-1013, April 2022. | DOI
DonnaBoll
Administrator
in
PBC Foundation
30 days ago
Reminder 'Off Topic'
Good morning everyone, Just a gentle reminder if your topic does not relate directly to Rheumatoid Arthritis please can I ask you to make your post 'Off Topic'. Thank you for your support on the matter. Kind Regards Tim - Head of Services NRAS
Good morning everyone, Just a gentle reminder if your topic does not relate directly to Rheumatoid Arthritis please can I ask you to make your post 'Off Topic'. Thank you for your support on the matter. Kind Regards Tim - Head of Services NRAS
Hidden
in
NRAS
6 months ago
Some good news to start the day: Complete Response in First Patient Ever Treated with 2 Doses of Cu-67 SAR-bisPSMA at 8GBq...6 months
I have already written about this, but then he approached the 6 months mark, so... "The patient remains with undetectable levels of Prostate Specific Antigen (PSA) for almost 6 months, following the administration of the second dose of 67Cu-SAR-bisPSMA. PSA is a marker used to assess clinical response
I have already written about this, but then he approached the 6 months mark, so... "The patient remains with undetectable levels of Prostate Specific Antigen (PSA) for almost 6 months, following the administration of the second dose of 67Cu-SAR-bisPSMA. PSA is a marker used to assess clinical response
Maxone73
in
Advanced Prostate Cancer
1 month ago
Lixisenatide as a treatment for early Parkinson’s disease progression
In this randomized controlled trial, lixisenatide reduced motor disability progression in Parkinson’s patients. 2. Individuals in the lixisenatide group experienced greater gastrointestinal side effects rates than individuals in the placebo group. Evidence Rating Level: 1 (Excellent) https:/
In this randomized controlled trial, lixisenatide reduced motor disability progression in Parkinson’s patients. 2. Individuals in the lixisenatide group experienced greater gastrointestinal side effects rates than individuals in the placebo group. Evidence Rating Level: 1 (Excellent) https:/
Farooqji
in
Cure Parkinson's
1 month ago
So the odds we all read about... are they true?
When my husband (age 52) was diagnosed with metastatic prostate cancer two and a half years ago, he was told the outlook was "grim." Everything we read told us once it moves to the bone (his has) then you're looking at months, not years, of life left. He had TEMPUS done, which was basically the oncologist
When my husband (age 52) was diagnosed with metastatic prostate cancer two and a half years ago, he was told the outlook was "grim." Everything we read told us once it moves to the bone (his has) then you're looking at months, not years, of life left. He had TEMPUS done, which was basically the oncologist
Anatalya
in
Advanced Prostate Cancer
1 month ago
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