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Radiation
I had the standard IMRT for my pca back in 2013. I was told it was a lifetime dose. Is that true with the newer forms of radiation treatment? I am faced with starting a six dose regimen of taxotere now since ADT does not seem to be working according to PSMA scans. My psa remains at 1.8 even though the
I had the standard IMRT for my pca back in 2013. I was told it was a lifetime dose. Is that true with the newer forms of radiation treatment? I am faced with starting a six dose regimen of taxotere now since ADT does not seem to be working according to PSMA scans. My psa remains at 1.8 even though the
sillyoyster
in
Advanced Prostate Cancer
10 months ago
Advice - supplement and diagnosis
Hi, I'm hoping for some advice on whether to pursue b12 def with my GP.... Some history for me (currently not diagnosed with a B12 deficiency) 2021 - GP - exhausted, burning pain in lower leg, pins and needles in feet, restless legs at night. All blood tests done (inc b12), told all normal, referred
Hi, I'm hoping for some advice on whether to pursue b12 def with my GP.... Some history for me (currently not diagnosed with a B12 deficiency) 2021 - GP - exhausted, burning pain in lower leg, pins and needles in feet, restless legs at night. All blood tests done (inc b12), told all normal, referred
Balloonbbb
in
Pernicious Anaemia Society
11 months ago
HRT and diarrhoea
I started HRT at 49 a few months back, not due to menopausal symptoms, but because I found my testosterone to be at the very bottom of range. The very good private hormone doctor I saw said HRT should balance my hormones and is a better way to increase testosterone than by giving testosterone (it did
I started HRT at 49 a few months back, not due to menopausal symptoms, but because I found my testosterone to be at the very bottom of range. The very good private hormone doctor I saw said HRT should balance my hormones and is a better way to increase testosterone than by giving testosterone (it did
CornishChick
in
Thyroid UK
11 months ago
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Perimenopausal and should I take hrt?
Hello, I am trying to assess whether I am perimenopausal or if I just have the usual under active thyroid symptoms. I'm 42 and struggle with the following symptoms...no sex drive and loss of ongoing dryness, headaches on one side of my head with constant tinnitus on this same side, tiredness and mood
Hello, I am trying to assess whether I am perimenopausal or if I just have the usual under active thyroid symptoms. I'm 42 and struggle with the following symptoms...no sex drive and loss of ongoing dryness, headaches on one side of my head with constant tinnitus on this same side, tiredness and mood
Auntbessy
in
Thyroid UK
11 months ago
Supraphysiological Androgens [SPA] Promote Tumor Suppressive Activity of the AR Through cMYC Repression and Recruitment of the DREAM Complex
New study [1]. I have struggled to understand how Denmeade’s BAT (Bipolar Androgen Therapy) depends on supraphysiological levels of androgen (testosterone = ~2,000 ng/dL), considering that Morgentaler’s saturation model has it that androgen receptors [ARs] have all the testosterone they can use at
New study [1]. I have struggled to understand how Denmeade’s BAT (Bipolar Androgen Therapy) depends on supraphysiological levels of androgen (testosterone = ~2,000 ng/dL), considering that Morgentaler’s saturation model has it that androgen receptors [ARs] have all the testosterone they can use at
pca2004
in
Fight Prostate Cancer
1 year ago
Hi All back again
Hope everyone is doing as well as can be expected
Hubby just had psa and testosterone test after being on Zoladex again this past nine months, this is his second round after having 6 weeks radiation and 2 years zoladex in 2013 inbetween 2015 and 2023 under control with watch and wait until
Hope everyone is doing as well as can be expected
Hubby just had psa and testosterone test after being on Zoladex again this past nine months, this is his second round after having 6 weeks radiation and 2 years zoladex in 2013 inbetween 2015 and 2023 under control with watch and wait until
Knittingque
in
Advanced Prostate Cancer
11 months ago
bowel endo issues
Hi all, I have deep infiltrated endo on my bowel (diagnosed via scan and mri 3 years ago) and superficial on my uterus but my bowel issues have been getting worse lately probably after all the pain medications and hormone treatment i’ve been trialling to avoid surgery! It’s to the point now I can
Hi all, I have deep infiltrated endo on my bowel (diagnosed via scan and mri 3 years ago) and superficial on my uterus but my bowel issues have been getting worse lately probably after all the pain medications and hormone treatment i’ve been trialling to avoid surgery! It’s to the point now I can
Karen_92
in
Endometriosis UK
11 months ago
I had a novasure 9 years ago. Very successful results. Now I’m on HRT and utrogestan isn’t agreeing with me. Can I have the mirena coil?
I had a novasure 9 years ago. Very successful results. Now I’m on HRT and utrogestan isn’t agreeing with me. Can I have the mirena coil?
I had a novasure 9 years ago. Very successful results. Now I’m on HRT and utrogestan isn’t agreeing with me. Can I have the mirena coil?
Rubberduckling
in
BASHH
11 months ago
Natural FET possibly cancelled
I had a failed fresh transfer at the beginning of June. The plan was made to try for a natural modified FET this month as my cycles are regular and the risk of prenatal hypertension with a hormone FET was not ideal for me. I had my day 10 scan on Thurs and my dominant follicle was already 14.5mm but
I had a failed fresh transfer at the beginning of June. The plan was made to try for a natural modified FET this month as my cycles are regular and the risk of prenatal hypertension with a hormone FET was not ideal for me. I had my day 10 scan on Thurs and my dominant follicle was already 14.5mm but
SMBCnewbie
in
Fertility Network UK
11 months ago
dilemma ADT duration
apologies first for another longish verbose posting ! I am in a dilemma after my last oncology appointment - I have T2cN0M0 G9 locally contained PCa following a failed HIFU that was previously twice biopsied as G7. After a clear PSMA showing locally contained with no SV involvement I had 20x3Gy to
apologies first for another longish verbose posting ! I am in a dilemma after my last oncology appointment - I have T2cN0M0 G9 locally contained PCa following a failed HIFU that was previously twice biopsied as G7. After a clear PSMA showing locally contained with no SV involvement I had 20x3Gy to
SimMartin
in
Advanced Prostate Cancer
11 months ago
Cognitive behavioural therapy
Hi, I've posted here before so just a quick update - RLS for 47 years, tried DAs, Gabapentin, Pregabalin and on Tramadol at the moment. I've been through augmentation. Tramadol is helping a bit but my sleep pattern is all over the place and I keep falling asleep in the afternoon. My daughter has had
Hi, I've posted here before so just a quick update - RLS for 47 years, tried DAs, Gabapentin, Pregabalin and on Tramadol at the moment. I've been through augmentation. Tramadol is helping a bit but my sleep pattern is all over the place and I keep falling asleep in the afternoon. My daughter has had
restlessinlondon
in
Restless Legs Syndrome
11 months ago
Back pain
Apologies in advance for the long post After a bit of a battle with Rheumatology I had a Pet scan back in February that was suggestive of mild PMR They had previously diagnosed me with Fibromyalgia at the age of 51 as I was far to young for PMR and my blood work was unremarkable I was given 15mg of Pred
Apologies in advance for the long post After a bit of a battle with Rheumatology I had a Pet scan back in February that was suggestive of mild PMR They had previously diagnosed me with Fibromyalgia at the age of 51 as I was far to young for PMR and my blood work was unremarkable I was given 15mg of Pred
Northernnugget
in
PMRGCAuk
11 months ago
Strategies to Re-Sensitize Castration-Resistant Prostate Cancer to Antiandrogen Therapy
New paper from Spain [1]. "... we will review those strategies and drugs that are able to resensitize cancer cells to previously used treatments through the use of "hinge" treatments with the objective of obtaining an oncological benefit. "
Some examples are:
[i]
bipolar androgen therapy (
New paper from Spain [1]. "... we will review those strategies and drugs that are able to resensitize cancer cells to previously used treatments through the use of "hinge" treatments with the objective of obtaining an oncological benefit. "
Some examples are:
[i]
bipolar androgen therapy (
pca2004
in
Fight Prostate Cancer
1 year ago
Bio Feedback
Has anyone had success with biofeedback? Our son is 13 and had dyspraxia, he can't locate his pelvic floor so as to engage the sensors at the hospital. Anyone have any suggestions on what we could do? We have 5 more sessions (4 hour round trip plus appointment) so it would be good to try and make
Has anyone had success with biofeedback? Our son is 13 and had dyspraxia, he can't locate his pelvic floor so as to engage the sensors at the hospital. Anyone have any suggestions on what we could do? We have 5 more sessions (4 hour round trip plus appointment) so it would be good to try and make
MrsSquirrel
in
ERIC
1 year ago
Casodex query
About to go back on ADT this month because my PSA is doubling every 4 months My Nader was 0.02 in April 2021 but recent bloods are showing 2:6 and I’m expecting 5 plus on bloods done yesterday I was told in March this year that I had incurable cancer after a clear PSMA scan on the previous February .
About to go back on ADT this month because my PSA is doubling every 4 months My Nader was 0.02 in April 2021 but recent bloods are showing 2:6 and I’m expecting 5 plus on bloods done yesterday I was told in March this year that I had incurable cancer after a clear PSMA scan on the previous February .
Walliam
in
Advanced Prostate Cancer
11 months ago
Et triple negative platlets gone up to 1560
Hi all, Just getting back on here about platlets increasing over 1500,My hematologist will want me on hydroxyurea as he said when I go over 1500 that is his way forward. The past 2 bloods I had done have come down from 1420 to 1402 to 1300 last time 6 weeks ago. I am just wondering if it has to be this
Hi all, Just getting back on here about platlets increasing over 1500,My hematologist will want me on hydroxyurea as he said when I go over 1500 that is his way forward. The past 2 bloods I had done have come down from 1420 to 1402 to 1300 last time 6 weeks ago. I am just wondering if it has to be this
Mike1974
in
MPN Voice
1 year ago
Radiation for Salvage Treatment
I am about to start salvage treatment after a failed surgery and a rising PSA value of 0.1. However, I would like to know if weeks of external radiation with ADT, is the best treatment option here. The idea of blindly radiating pelvic area with a re-recurrence a few years later does not appeal to me.
I am about to start salvage treatment after a failed surgery and a rising PSA value of 0.1. However, I would like to know if weeks of external radiation with ADT, is the best treatment option here. The idea of blindly radiating pelvic area with a re-recurrence a few years later does not appeal to me.
Rams91
in
Prostate Cancer Network
11 months ago
Help with blood test results please
Hello I have a phone appointment on Monday to discuss these results with my GP, but in order to arm myself with the right info, can anyone help me to interpret the attached please? Background: I am 44 years old and started HRT about 5 months ago, having had symptoms for the last few years. I am on
Hello I have a phone appointment on Monday to discuss these results with my GP, but in order to arm myself with the right info, can anyone help me to interpret the attached please? Background: I am 44 years old and started HRT about 5 months ago, having had symptoms for the last few years. I am on
Jellybabyhead
in
Thyroid UK
11 months ago
Parent of Adult child refusing change
my adult daughter who is over 40, single and cannot hold a job, is constantly late, has difficulty with cleaning her spaces, delays her medical care, etc... and cannot support herself. She refuses to apply for benefits and is extremely resistant to behavioral therapy relying only on her medication
my adult daughter who is over 40, single and cannot hold a job, is constantly late, has difficulty with cleaning her spaces, delays her medical care, etc... and cannot support herself. She refuses to apply for benefits and is extremely resistant to behavioral therapy relying only on her medication
Password5
in
CHADD's Adult ADHD Support
1 year ago
Help with blood test results
Hello I am calling tomorrow to discuss these results with my GP, but in order to arm myself with the right info, can anyone help me to interpret the attached please? Background: I am 44 years old and started HRT about 5 months ago. I am on the mini pill (Detrogel) and at the time of blood draw (yesterday
Hello I am calling tomorrow to discuss these results with my GP, but in order to arm myself with the right info, can anyone help me to interpret the attached please? Background: I am 44 years old and started HRT about 5 months ago. I am on the mini pill (Detrogel) and at the time of blood draw (yesterday
Jellybabyhead
in
Menopause and Perimenopause Support
11 months ago
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