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I was diagnosed with major depressive disorder over 5 years ago. It started with speech therapy but didn’t seem to help. I’ve been medicated since then but it doesn’t feel like it’s doing its job anymore. The last couple years have been a rollercoaster with changing meds multiple times, worsening depression
I was diagnosed with major depressive disorder over 5 years ago. It started with speech therapy but didn’t seem to help. I’ve been medicated since then but it doesn’t feel like it’s doing its job anymore. The last couple years have been a rollercoaster with changing meds multiple times, worsening depression
RottieFlood37
in
Major Depressive Disorder (MDD) Support
10 months ago
thyroid results
Could someone please help me understand my blood results which I had done by Medichecks (home testing kit) I have had underactive thyroid for the past 25years The doctors are always changing the brands I take I hadn’t had my thyroid levels tested for nearly 5 years with my GP, it’s as if they’d
Could someone please help me understand my blood results which I had done by Medichecks (home testing kit) I have had underactive thyroid for the past 25years The doctors are always changing the brands I take I hadn’t had my thyroid levels tested for nearly 5 years with my GP, it’s as if they’d
Horsemadlindy21
in
Thyroid UK
6 months ago
non hormonal suggestions
hi! I was diagnosed with endo in 2019, avoided any hormonal treatment until last year due to past experiences of the pill. March last yr I went for a private fertility check and they said my endo looked worse and was now also adenomyosis. Suggestion was a mirena coil to stop periods. I went for
hi! I was diagnosed with endo in 2019, avoided any hormonal treatment until last year due to past experiences of the pill. March last yr I went for a private fertility check and they said my endo looked worse and was now also adenomyosis. Suggestion was a mirena coil to stop periods. I went for
Sophiealice_
in
Endometriosis UK
6 months ago
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Did you use Orgovyx with radiation, and did your Medicare Part D or Advantage plan cover it ?
I'm hoping to learn what roadblocks anyone encountered in asking to use Orgovyx instead of Lupron, etc as part of radiation treatment. Resistance from prescribing ROs? Problems with Part D drug coverage ? Advantage plans...Kaiser , etc............that would and wouldn't cover at least some of the
I'm hoping to learn what roadblocks anyone encountered in asking to use Orgovyx instead of Lupron, etc as part of radiation treatment. Resistance from prescribing ROs? Problems with Part D drug coverage ? Advantage plans...Kaiser , etc............that would and wouldn't cover at least some of the
maley2711
in
Advanced Prostate Cancer
6 months ago
Saliva Cortisol results, the investigation continues...
Hi everyone 😊, Me again! My investigations continue and this is my most recent test to try to piece together what's going on. Any input most welcome please 🙏 Backstory since joining HU last November - Iron deficiency anaemia now corrected and ferritin getting close to optimal. All other vitamins
Hi everyone 😊, Me again! My investigations continue and this is my most recent test to try to piece together what's going on. Any input most welcome please 🙏 Backstory since joining HU last November - Iron deficiency anaemia now corrected and ferritin getting close to optimal. All other vitamins
Bertiepuss
in
Thyroid UK
6 months ago
Addition of an ARSI to standard ADT significantly increases the risk of fractures and falls in men with prostate cancer
Jones C, Gray S, Brown M, et al. Risk of fractures and falls in men with advanced or metastatic prostate cancer receiving androgen deprivation therapy and treated with novel androgen receptor signalling inhibitors: a systematic review and meta-analysis of randomised controlled trials. Eur Urol Oncol.
Jones C, Gray S, Brown M, et al. Risk of fractures and falls in men with advanced or metastatic prostate cancer receiving androgen deprivation therapy and treated with novel androgen receptor signalling inhibitors: a systematic review and meta-analysis of randomised controlled trials. Eur Urol Oncol.
Graham49
in
Advanced Prostate Cancer
6 months ago
Starting clinical trial of AVR-766
Today I start a clinical trial for ARV-766, an AR degrader. I'm coming in at phase 2, and they are only accepting men who have one of 4 point mutations in the AR - I have two. I've been randomized to 300 mg pill, once a day. The other dose is 100mg. I've failed ADT, chemo. Keytruda & Pluvicto. Hoping
Today I start a clinical trial for ARV-766, an AR degrader. I'm coming in at phase 2, and they are only accepting men who have one of 4 point mutations in the AR - I have two. I've been randomized to 300 mg pill, once a day. The other dose is 100mg. I've failed ADT, chemo. Keytruda & Pluvicto. Hoping
rsgdmd
in
Advanced Prostate Cancer
6 months ago
Sporadically fall backwards with no warning
3 weeks into new dose of 100 levothyroxine (on waking) + 2 doses of 7.5 t3 (one on waking and one at 3pm - [built up gradually]). Back to suddenly, out of nowhere just falling backwards and fatigue beyond all comprehension. This falling symptom only started after my 15 days off levothyroxine, nearly
3 weeks into new dose of 100 levothyroxine (on waking) + 2 doses of 7.5 t3 (one on waking and one at 3pm - [built up gradually]). Back to suddenly, out of nowhere just falling backwards and fatigue beyond all comprehension. This falling symptom only started after my 15 days off levothyroxine, nearly
woofa27
in
Thyroid UK
6 months ago
Constantly bleeding / zoladex
I'm coming to to my 3rd shot of zoladex next week but for the last 5 weeks I've had 3 periods and all have been a week long. I had 5 days respite between 2 and my current period. I'm currently on day 7 and is not letting up, so don't know how much longer this 3rd will go on for. They aren't light,
I'm coming to to my 3rd shot of zoladex next week but for the last 5 weeks I've had 3 periods and all have been a week long. I had 5 days respite between 2 and my current period. I'm currently on day 7 and is not letting up, so don't know how much longer this 3rd will go on for. They aren't light,
Aino26
in
Endometriosis UK
6 months ago
Is there any evidence that ADT deteriorates the myelin insulating neuropathways?
That's the question.
That's the question.
Eadgbe
in
Advanced Prostate Cancer
6 months ago
Rising PCA - on ADT Holiday
Diagnosed Stage 4 oligometastatic (low volume) PCA in 2021. Gleason 7, 4+3 . Completed RT and 18 months on ADT (Nubeqa) paused the ADT in September after PSA non detectable and a fresh set of scans showed no “evidence of disease”. Continued to do bloodwork quarterly and PSA remained at 0. Until
Diagnosed Stage 4 oligometastatic (low volume) PCA in 2021. Gleason 7, 4+3 . Completed RT and 18 months on ADT (Nubeqa) paused the ADT in September after PSA non detectable and a fresh set of scans showed no “evidence of disease”. Continued to do bloodwork quarterly and PSA remained at 0. Until
Kkash
in
Advanced Prostate Cancer
6 months ago
Reassurance please
Hi, I have a diagnosis of an autoimmune thyroid condition. Went privately as NHS tests all within range on tests. Waiting on further bloods, which has been difficult to get done, so I can have follow up appointment with private GP for thyroid treatment. Appointment in July. In the interim I did see NHS
Hi, I have a diagnosis of an autoimmune thyroid condition. Went privately as NHS tests all within range on tests. Waiting on further bloods, which has been difficult to get done, so I can have follow up appointment with private GP for thyroid treatment. Appointment in July. In the interim I did see NHS
Fizzwhizz
in
Thyroid UK
6 months ago
Urinary urgency after treatment .. occasional
One side effect I’ve noticed is an occasional sudden need to urinate. Like when you were a young kid stuck on a school bus and had to really really go. This doesn’t happen all the time but maybe 20% of the time so several times a day. I’ve had brachytherapy (5 months ago), external radiation (3 months
One side effect I’ve noticed is an occasional sudden need to urinate. Like when you were a young kid stuck on a school bus and had to really really go. This doesn’t happen all the time but maybe 20% of the time so several times a day. I’ve had brachytherapy (5 months ago), external radiation (3 months
Yokohama2023
in
Prostate Cancer Network
6 months ago
Impact of brief CBT on chronic pain and anxiety
Hello, My name is Audrey and I am a student at Pepperdine University. I am doing a research study about the impact of brief Cognitive Behavioral Therapy on people with chronic pain and anxiety. I would appreciate it if you could take a few minutes to complete both parts. It will also expose you to a
Hello, My name is Audrey and I am a student at Pepperdine University. I am doing a research study about the impact of brief Cognitive Behavioral Therapy on people with chronic pain and anxiety. I would appreciate it if you could take a few minutes to complete both parts. It will also expose you to a
audreycosta
in
Pain Concern
6 months ago
Does this sound like Hashimoto's please?
Hello, My thyroid has been under suspicion for many years but I cannot seem to get any answers. Postnatally, (four months after giving birth), some fifteen years ago, my TSH was tested and was 12.6. Nothing was done about this. ( I have only just seen this on my NHS app). Fast forward to eight years
Hello, My thyroid has been under suspicion for many years but I cannot seem to get any answers. Postnatally, (four months after giving birth), some fifteen years ago, my TSH was tested and was 12.6. Nothing was done about this. ( I have only just seen this on my NHS app). Fast forward to eight years
Gyrosgirl
in
Thyroid UK
6 months ago
Tibolone HRT offered for pain relief of Pudendal Nueralgia alongside 3 injections of Zoladex into the abdominal wall?
Hi everyone, I had a gynecologist offer me Tibolone HRT tablets alongside 3 injections of Zoladex into the abdominal wall 4x weekly. Looking these medications up I've seen a ton of side effects like most meds. The gynaecologist agreed I had normal hormones and no gyno problems or endometriosis but being
Hi everyone, I had a gynecologist offer me Tibolone HRT tablets alongside 3 injections of Zoladex into the abdominal wall 4x weekly. Looking these medications up I've seen a ton of side effects like most meds. The gynaecologist agreed I had normal hormones and no gyno problems or endometriosis but being
Jobie18
in
Pelvic Pain Support Network
6 months ago
Another question: did anyone have all their joints crunching, clicking, and sore when their b12 dropped into deficiency range?
Another question: did anyone have all their joints crunching, clicking, and sore when their b12 dropped into deficiency range? My joints in my spine, and hips, shoulder, especially. They click and crunch since I dipped into serious neuro symptoms when b12 likely tanked last September. I also had genitourinary
Another question: did anyone have all their joints crunching, clicking, and sore when their b12 dropped into deficiency range? My joints in my spine, and hips, shoulder, especially. They click and crunch since I dipped into serious neuro symptoms when b12 likely tanked last September. I also had genitourinary
Suffering_sunny
in
Pernicious Anaemia Society
6 months ago
Affect of Alendronic acid if needing dental work?
This aspect bothers me as well as the implications of taking Alendronic acid. At age 81 after taking AA for about 18 months, I stopped it after I was prescribed HRT patches for another problem . Whilst HRT protects bones to a certain extent , I believe it doesn't increase bone density as does AA.
This aspect bothers me as well as the implications of taking Alendronic acid. At age 81 after taking AA for about 18 months, I stopped it after I was prescribed HRT patches for another problem . Whilst HRT protects bones to a certain extent , I believe it doesn't increase bone density as does AA.
moconnolly
in
PMRGCAuk
6 months ago
Treatment Options
PSA 4.7 (over 2 years it double and then doubled again) This is the Pathology report A: Prostate gland, left lateral posterior, biopsy: Benign prostatic tissue with mild chronic inflammation, no tumor present. B: Prostate gland, left lateral mid, biopsy: Benign prostatic tissue with mild chronic
PSA 4.7 (over 2 years it double and then doubled again) This is the Pathology report A: Prostate gland, left lateral posterior, biopsy: Benign prostatic tissue with mild chronic inflammation, no tumor present. B: Prostate gland, left lateral mid, biopsy: Benign prostatic tissue with mild chronic
Vortex12
in
Prostate Cancer Network
9 months ago
High TSH and High T4
Hi all! Hoping someone can answer this for me. The last week I have been getting serious symptoms with bradycardia, PVCs, and then Tachycardia, sweating, chest pressure/tightness, severe arm and leg aches. I finally ended up going to emergency. They kept me for observation and checked my heart which
Hi all! Hoping someone can answer this for me. The last week I have been getting serious symptoms with bradycardia, PVCs, and then Tachycardia, sweating, chest pressure/tightness, severe arm and leg aches. I finally ended up going to emergency. They kept me for observation and checked my heart which
brethor9
in
Thyroid UK
6 months ago
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