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Janssen tables prostate cancer study due to enrollment troubles
After a fruitless search for patients with a specific type of prostate cancer, Janssen is suspending a phase 1 clinical trial that was being conducted with ESSA Pharma’s experimental small-molecule inhibitor. Janssen tables prostate cancer study due to enrollment troubles https://www.fiercebiotech.com
After a fruitless search for patients with a specific type of prostate cancer, Janssen is suspending a phase 1 clinical trial that was being conducted with ESSA Pharma’s experimental small-molecule inhibitor. Janssen tables prostate cancer study due to enrollment troubles https://www.fiercebiotech.com
cesces
in
Advanced Prostate Cancer
2 years ago
Prostate Cancer-Thoughts
My husband was diagnosed in January 2020 with prostate cancer that had metastasized to his bones. His PSA was 30 and after the biopsy it was 130. He has had radiation three different times, Firmagon, Zytiga and Prednisone. His testosterone is low and his PSA did get as low as 2 but then started rising
My husband was diagnosed in January 2020 with prostate cancer that had metastasized to his bones. His PSA was 30 and after the biopsy it was 130. He has had radiation three different times, Firmagon, Zytiga and Prednisone. His testosterone is low and his PSA did get as low as 2 but then started rising
margretrburns
in
Advanced Prostate Cancer
2 years ago
ADAA Blog: "Your “Strong” Friends Need Checking in on Too: Despair and High Functioning Depression"
Many people believe that if someone seems to have "their life together" then they must be doing fine. But those people who seem "strong" emotionally may actually be suffering from something not seen, like depression. Maybe someone came to your mind when reading this. Check on them, and see how they're
Many people believe that if someone seems to have "their life together" then they must be doing fine. But those people who seem "strong" emotionally may actually be suffering from something not seen, like depression. Maybe someone came to your mind when reading this. Check on them, and see how they're
ADAATeamRachel
Administrator
in
Anxiety and Depression Support
2 years ago
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All good things must come to an end
I just had my 3 month checkup and it looks like my Ibrutinib is starting to stop keeping my counts in check. They have not gone crazy but have been slowing rising this past year and actually doubled over a 6 month period. My Doctor thinks it's probably good to look at another treatment while I am still
I just had my 3 month checkup and it looks like my Ibrutinib is starting to stop keeping my counts in check. They have not gone crazy but have been slowing rising this past year and actually doubled over a 6 month period. My Doctor thinks it's probably good to look at another treatment while I am still
rcusher
in
CLL Support
2 years ago
Effects of cocoa extract and a multivitamin on cognitive function: A randomized clinical trial
Abstract Introduction Dietary supplements are touted for cognitive protection, but supporting evidence is mixed. COSMOS-Mind tested whether daily administration of cocoa extract (containing 500 mg/day flavanols) versus placebo and a commercial multivitamin-mineral (MVM) versus placebo improved cognition
Abstract Introduction Dietary supplements are touted for cognitive protection, but supporting evidence is mixed. COSMOS-Mind tested whether daily administration of cocoa extract (containing 500 mg/day flavanols) versus placebo and a commercial multivitamin-mineral (MVM) versus placebo improved cognition
RedApple
Administrator
in
Thyroid UK
2 years ago
Getting a rhinoplasty (nose job) in 5 days. Anything I can do to tell myself I’ll be OK?
Hello everyone I haven’t posted to the forums in a while. I’m now seeing a therapist and have noticed a significant improvement in most of my anxiety issues, including the physical symptoms that I mentioned months ago. In a little under a week I’ll be getting a nose job (something I’ve wanted since middle
Hello everyone I haven’t posted to the forums in a while. I’m now seeing a therapist and have noticed a significant improvement in most of my anxiety issues, including the physical symptoms that I mentioned months ago. In a little under a week I’ll be getting a nose job (something I’ve wanted since middle
Mimi1114
in
Anxiety and Depression Support
2 years ago
Am I being irresponsible asking this question
I'm currently 4 months into a clinical trial and have chemo 3 weeks on, 1 week off, plus the the trial drug. I've really struggled with the regime as I was unwell before I started chemo and I've been plagued with lots of other problems as well. I can have a maximum of 6 months of chemo which takes
I'm currently 4 months into a clinical trial and have chemo 3 weeks on, 1 week off, plus the the trial drug. I've really struggled with the regime as I was unwell before I started chemo and I've been plagued with lots of other problems as well. I can have a maximum of 6 months of chemo which takes
doodoolatrice
in
My Ovacome
2 years ago
Olaparib combined with cediranib improved radiographic progression-free survival (rPFS) in phase 2 clinical
From Renal and Urology news. Olaparib combined with cediranib improves radiographic progression-free survival (rPFS) compared with olaparib alone in men with metastatic castration-resistant prostate cancer (mCRPC), results from a recent randomized phase 2 clinical trial suggest. In an analysis of
From Renal and Urology news. Olaparib combined with cediranib improves radiographic progression-free survival (rPFS) compared with olaparib alone in men with metastatic castration-resistant prostate cancer (mCRPC), results from a recent randomized phase 2 clinical trial suggest. In an analysis of
Graham49
in
Advanced Prostate Cancer
2 years ago
InSightec has registered a trial of intracerebral delivery of GCase (via MR-guided focused ultrasound)
https://clinicaltrials.gov/ct2/show/NCT05565443 New clinical trial registered: InSightec has registered a two-arm, open-label study to establish safety & feasibility of intracerebral delivery of GCase (via MR-guided focused ultrasound) in 14 individuals with Parkinsons (7 GBA-PD & 7 iPD)
https://clinicaltrials.gov/ct2/show/NCT05565443 New clinical trial registered: InSightec has registered a two-arm, open-label study to establish safety & feasibility of intracerebral delivery of GCase (via MR-guided focused ultrasound) in 14 individuals with Parkinsons (7 GBA-PD & 7 iPD)
Hidden
in
Cure Parkinson's
2 years ago
weekly taxol
hi all, Firstly just want to say to everyone — good luck in your treatments and I hope you are all doing well and keeping positive ! is anyone on weekly taxol ? If so , how are you doing —- and has anyone finished weekly taxol and moved on to another treatment ???? my next option is weekly taxol although
hi all, Firstly just want to say to everyone — good luck in your treatments and I hope you are all doing well and keeping positive ! is anyone on weekly taxol ? If so , how are you doing —- and has anyone finished weekly taxol and moved on to another treatment ???? my next option is weekly taxol although
Lookingahead
in
My Ovacome
2 years ago
Clinical trial for new stem cell-based treatment for Parkinson’s disease given go ahead
The Swedish Medical Products Agency has granted approval for the trial to proceed; ethical approval has already been obtained from the Swedish Ethics Review Authority. The team, led from Lund University in Sweden, is poised to begin recruitment. STEM-PD uses human embryonic stem cells, a type of cell
The Swedish Medical Products Agency has granted approval for the trial to proceed; ethical approval has already been obtained from the Swedish Ethics Review Authority. The team, led from Lund University in Sweden, is poised to begin recruitment. STEM-PD uses human embryonic stem cells, a type of cell
Farooqji
in
Cure Parkinson's
2 years ago
video: Low-dose ketamine produces long-term reduction in levodopa-induced dyskinesia
https://youtu.be/4sygods1Txk Preclinical data has previously suggested that low-dose ketamine treatment has short-term antiparkinsonian activity and can reduce levodopa-induced dyskinesia in the long term after an initial 10-hour total treatment. Torsten Falk, PhD, University of Arizona, Tuscon, AZ
https://youtu.be/4sygods1Txk Preclinical data has previously suggested that low-dose ketamine treatment has short-term antiparkinsonian activity and can reduce levodopa-induced dyskinesia in the long term after an initial 10-hour total treatment. Torsten Falk, PhD, University of Arizona, Tuscon, AZ
Hidden
in
Cure Parkinson's
2 years ago
Daughter Supporting Father
Hi everyone, I feel very grateful to have found this resource. I am new here, and I am a 31 y/o daughter who (along with my mom) has been supporting my (almost) 78 year-old father battle Stage IV prostate cancer since January 2017. He has been in and out of remission over the course of time. Some context
Hi everyone, I feel very grateful to have found this resource. I am new here, and I am a 31 y/o daughter who (along with my mom) has been supporting my (almost) 78 year-old father battle Stage IV prostate cancer since January 2017. He has been in and out of remission over the course of time. Some context
Sunnyday1122
in
Advanced Prostate Cancer
2 years ago
Nitric Oxide -- slows prostate cancer progression and PSA doubling time.
Note the articles title and published date on NIH.gov:
"
[u]
Current Advances
[/u]
of Nitric Oxide in Cancer and Anticancer Therapeutics"
Published online
[u]
2021 Jan 27
[/u] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7912608/ Also see malecare article below
Note the articles title and published date on NIH.gov:
"
[u]
Current Advances
[/u]
of Nitric Oxide in Cancer and Anticancer Therapeutics"
Published online
[u]
2021 Jan 27
[/u] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7912608/ Also see malecare article below
George71
in
Fight Prostate Cancer
2 years ago
High Dose Testosterone for ATM, CDK12 or CHEK2 Altered Prostate Cancers (VA-BAT) clinical trial
Apologies if this has been posted: https://clinicaltrials.gov/ct2/show/NCT05011383
Apologies if this has been posted: https://clinicaltrials.gov/ct2/show/NCT05011383
swwags
in
Advanced Prostate Cancer
2 years ago
Next treatment options
Greetings, I've completed my 13th session of cabazitaxel/carboplatin + daily prednisone which started in Jan of this year. I've tolerated it well with minimal size effects (peripheral neuropathy) and no nausea. I'm also getting Zometa every 4 weeks and Lupron twice/year. Bone mets on my last Bone (July
Greetings, I've completed my 13th session of cabazitaxel/carboplatin + daily prednisone which started in Jan of this year. I've tolerated it well with minimal size effects (peripheral neuropathy) and no nausea. I'm also getting Zometa every 4 weeks and Lupron twice/year. Bone mets on my last Bone (July
MechD
in
Advanced Prostate Cancer
2 years ago
Update of Mithradite Trial
I am now one year into the Mithradite trial and thought a good time for update. The Mithradite trial is a randomised trial of Ruxolitnib against best available therapy which is either Hydrea or Interferon. My background is diagnosed with ET three years at age 67 and prescribed Hydrea. The Hydrea
I am now one year into the Mithradite trial and thought a good time for update. The Mithradite trial is a randomised trial of Ruxolitnib against best available therapy which is either Hydrea or Interferon. My background is diagnosed with ET three years at age 67 and prescribed Hydrea. The Hydrea
JP1952
in
MPN Voice
2 years ago
Addiction drug shows promise lifting long COVID brain fog, fatigue
Addiction drug shows promise lifting long COVID brain fog, fatigue By Julie Steenhuysen CHICAGO, Oct 18 (Reuters) - Lauren Nichols, a 34-year-old logistics expert for the U.S. Department of Transportation in Boston, has been suffering from impaired thinking and focus, fatigue, seizures, headache and
Addiction drug shows promise lifting long COVID brain fog, fatigue By Julie Steenhuysen CHICAGO, Oct 18 (Reuters) - Lauren Nichols, a 34-year-old logistics expert for the U.S. Department of Transportation in Boston, has been suffering from impaired thinking and focus, fatigue, seizures, headache and
lupus-support1
Administrator
in
LUpus Patients Understanding and Support
2 years ago
Metastatic breast cancer
Hi everyone! I've been having chemo for 2 years. Doctor still trying to find me a new med. I have metastatic breast cancer IV and has gone to my bones. I seem to be going backwards since diagnosed in 2016 with just breast cancer. I get depressed more and don't like when before I had so much energy. 😔
Hi everyone! I've been having chemo for 2 years. Doctor still trying to find me a new med. I have metastatic breast cancer IV and has gone to my bones. I seem to be going backwards since diagnosed in 2016 with just breast cancer. I get depressed more and don't like when before I had so much energy. 😔
Bubba_6
in
SHARE Breast Cancer Support
2 years ago
ACCELERATED MIGRATION AND INVASION OF PROSTATE CANCER CELLS AFTER A PHOTODYNAMIC THERAPY-LIKE CHALLENGE: ROLE OF NITRIC OXIDE
I'm trying to dig deeper into whether Nitric Oxide Patches would slow APC or not. I know that the one canadian study in 2011 had 16 of 17 patients slow or stabilize their PSA growth but could that be due to the timing of the NO usage, which was very soon after their recurrence? These two studies below
I'm trying to dig deeper into whether Nitric Oxide Patches would slow APC or not. I know that the one canadian study in 2011 had 16 of 17 patients slow or stabilize their PSA growth but could that be due to the timing of the NO usage, which was very soon after their recurrence? These two studies below
GeorgeGlass
in
Advanced Prostate Cancer
2 years ago
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