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Another BiTE gets spit out
As we are all painfully aware, prostate cancer is immunologically "cold." This means the immune system cannot be coaxed into attacking it. The one exception is Provenge. BiTEs (Bispecific T-cell Engagers) are in clinical trials. BiTEs are medicines that have one "hook" that connects to a cancer cell
As we are all painfully aware, prostate cancer is immunologically "cold." This means the immune system cannot be coaxed into attacking it. The one exception is Provenge. BiTEs (Bispecific T-cell Engagers) are in clinical trials. BiTEs are medicines that have one "hook" that connects to a cancer cell
Tall_Allen
in
Advanced Prostate Cancer
9 months ago
Can 4 minutes a day save your life? New study touts benefits of even brief exercise
Hebrew University researcher says study showing short-burst intense physical activity can lower risk of cancer by up to 32% is proof ‘doing something is better than doing nothing’ By RENEE GHERT-ZAND 3 August 2023 According to a new study, you don’t need to run, swim, bike or go to the gym to significantly
Hebrew University researcher says study showing short-burst intense physical activity can lower risk of cancer by up to 32% is proof ‘doing something is better than doing nothing’ By RENEE GHERT-ZAND 3 August 2023 According to a new study, you don’t need to run, swim, bike or go to the gym to significantly
lupus-support1
Administrator
in
LUpus Patients Understanding and Support
9 months ago
Duloxetine
I am also predisposed to familial
clinical
depression
and have had that on and off since I was a teenager. I've tried many SSRIs over the years but whilst they were okay, I never felt like myself. I'm usually a glass half full person. Fast forward to my third week on 30mg of Duloxetine.
I am also predisposed to familial
clinical
depression
and have had that on and off since I was a teenager. I've tried many SSRIs over the years but whilst they were okay, I never felt like myself. I'm usually a glass half full person. Fast forward to my third week on 30mg of Duloxetine.
Hoffgrad
in
Fibromyalgia Action UK
7 months ago
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Tamarack Clinical Trial
Has anyone enrolled in this latest targeted (non PSMA) treatmentt?
Has anyone enrolled in this latest targeted (non PSMA) treatmentt?
u302000
in
Advanced Prostate Cancer
9 months ago
HISTORIC FIRST! Microchips implanted into paralyzed man allows him to move hand and arm!
[i]It's still about the[/i][i]
BRAIN
[/i][i], right?[/i] [i]Have confidence! Science will SAVE us![/i] [i]
------------------------------------------------
[/i] [u]
Summary:
[/u] In a historic clinical trial, researchers successfully implanted microchips into the brain of a paralyzed
[i]It's still about the[/i][i]
BRAIN
[/i][i], right?[/i] [i]Have confidence! Science will SAVE us![/i] [i]
------------------------------------------------
[/i] [u]
Summary:
[/u] In a historic clinical trial, researchers successfully implanted microchips into the brain of a paralyzed
PDWarrior1900
in
Cure Parkinson's
9 months ago
New technique modifies T-Cells to cure cancer
From a publicly available site Scientists have stumbled upon an extraordinary 'living drug' in the bloodwork of a late-stage cancer survivor. A year after receiving "the biggest development in cancer therapy" in over 50 years, this patient's body was still protected by a fleet of souped-up killer
From a publicly available site Scientists have stumbled upon an extraordinary 'living drug' in the bloodwork of a late-stage cancer survivor. A year after receiving "the biggest development in cancer therapy" in over 50 years, this patient's body was still protected by a fleet of souped-up killer
Derf4223
in
Advanced Prostate Cancer
9 months ago
Micro-robots could deliver drugs to brain and organs
[i]A Bionaut robot compared to a penny. Photo by Bionaut Labs[/i] Bionaut Labs CEO says in the future illnesses that now seem incurable will be treated by medication delivered straight to the affected organ. Robotics entrepreneurs Michael Shpigelmacher, Aviad Maizels and Alex Shpunt were not looking
[i]A Bionaut robot compared to a penny. Photo by Bionaut Labs[/i] Bionaut Labs CEO says in the future illnesses that now seem incurable will be treated by medication delivered straight to the affected organ. Robotics entrepreneurs Michael Shpigelmacher, Aviad Maizels and Alex Shpunt were not looking
lupus-support1
Administrator
in
LUpus Patients Understanding and Support
9 months ago
lithium
hi I have started in lithium and get my first blood test in 3 days. Should I have been given a pack containing blood record book, leaflet and alert card or so they not do this anymore. Thanks
hi I have started in lithium and get my first blood test in 3 days. Should I have been given a pack containing blood record book, leaflet and alert card or so they not do this anymore. Thanks
onicha
in
NRAS
1 year ago
AOH1996 - CPNA inhibitor
»Everybody» has seen the news where City of Hope Dr Malkas claims very good results from preclinical tests - all 70 cell lines cancer cells annihilated, patients in the clinical trial 1 doing well. The information is vague, has anybody in here more information or will try to participate in the trial
»Everybody» has seen the news where City of Hope Dr Malkas claims very good results from preclinical tests - all 70 cell lines cancer cells annihilated, patients in the clinical trial 1 doing well. The information is vague, has anybody in here more information or will try to participate in the trial
Hidden
in
Fight Prostate Cancer
9 months ago
Bomedemstat trials
Hi everyone, I haven’t posted for a while as I’ve been trying to ignore this condition! Calr positive ET. I’m terrified of going back on Hydrea due to intolerable side effects and my very understanding MPN specialist nurse has been monitoring me. Sadly, my platelets are creeping up , lately to 845
Hi everyone, I haven’t posted for a while as I’ve been trying to ignore this condition! Calr positive ET. I’m terrified of going back on Hydrea due to intolerable side effects and my very understanding MPN specialist nurse has been monitoring me. Sadly, my platelets are creeping up , lately to 845
myllo
in
MPN Voice
9 months ago
Bomedemstat trials
Hi everyone, I haven’t posted for a while as I’ve been trying to ignore this condition! Calr positive ET. I’m terrified of going back on Hydrea due to intolerable side effects and my very understanding MPN specialist nurse has been monitoring me. Sadly, my platelets are creeping up , lately to 845
Hi everyone, I haven’t posted for a while as I’ve been trying to ignore this condition! Calr positive ET. I’m terrified of going back on Hydrea due to intolerable side effects and my very understanding MPN specialist nurse has been monitoring me. Sadly, my platelets are creeping up , lately to 845
myllo
in
MPN Voice
9 months ago
PCNA gene attack -- for solid tumors
Pasted from a publicly avaiilable website A "holy grail" molecule that kills all solid cancer tumors, leaving other cells unaffected, has been developed by scientists. The team at the City of Hope, one of the largest cancer research and treatment organizations in the United States, made the breakthrough
Pasted from a publicly avaiilable website A "holy grail" molecule that kills all solid cancer tumors, leaving other cells unaffected, has been developed by scientists. The team at the City of Hope, one of the largest cancer research and treatment organizations in the United States, made the breakthrough
Derf4223
in
Advanced Prostate Cancer
9 months ago
New Pancreatitis Therapies: Current Clinical Trials! | Webinar Registration is now OPEN
August 15, 2023 | 10 AM PT | 1 PM EST
Join our informative webinar, “New Pancreatitis Therapies: Current Clinical Trials!” where we aim to educate and empower you, our pancreatitis community, about the latest research and therapies available for pancreatitis. This session will provide information
August 15, 2023 | 10 AM PT | 1 PM EST
Join our informative webinar, “New Pancreatitis Therapies: Current Clinical Trials!” where we aim to educate and empower you, our pancreatitis community, about the latest research and therapies available for pancreatitis. This session will provide information
Skye_MC
Administrator
in
Chronic Pancreatitis Support
9 months ago
Mirtazapine 15mg
I was wondering if people could share their views taking Mirtazapine here. I’m 14 nights in taking it and was wondering what experiences of others were like. I was diagnosed with Anxiety, depression and stress. When do you feel the full benefits and what were your experiences. Thanks
I was wondering if people could share their views taking Mirtazapine here. I’m 14 nights in taking it and was wondering what experiences of others were like. I was diagnosed with Anxiety, depression and stress. When do you feel the full benefits and what were your experiences. Thanks
Hope__23
in
Anxiety and Depression Support
1 year ago
Trametinib MAPK inhibitor in ENZA-R pCA - very interesting
Many of us are ENZA resistant in the CRPC phase. In preclinical study in turns out that Trametinib + Enza has a profound effect on proliferation, especially with PTEN loss and PI3K mutations, the pCa is then very dependent on the MAPK signalling pathway. There is a clinical trial II open for new patients
Many of us are ENZA resistant in the CRPC phase. In preclinical study in turns out that Trametinib + Enza has a profound effect on proliferation, especially with PTEN loss and PI3K mutations, the pCa is then very dependent on the MAPK signalling pathway. There is a clinical trial II open for new patients
Hidden
in
Advanced Prostate Cancer
9 months ago
BMB in Two Days
I have my bmb scheduled for two days from now. My anxiety is "through the roof". I believe my hematologist originally thought I have ET. I am Calr 1 positive. However, her notes after the last visit state that the results of my bloodwork/tests are "consistent with an MPN, either ET or pre-pmf. Overt
I have my bmb scheduled for two days from now. My anxiety is "through the roof". I believe my hematologist originally thought I have ET. I am Calr 1 positive. However, her notes after the last visit state that the results of my bloodwork/tests are "consistent with an MPN, either ET or pre-pmf. Overt
Mtnlife
in
MPN Voice
1 year ago
If your doctor worries that too much B12 is toxic, show them this study on ALS & B12
ALS is the same as Lou Gehrig's disease, and is also what Stephen Hawking had. It is a neurodegenerative disease, thought to mostly affect the motor neurons. Ryosuke Oki, et al, "Efficacy and Safety of Ultrahigh-Dose Methylcobalamin in Early-Stage Amyotrophic Lateral Sclerosis" JAMA Neurol. 2022;
ALS is the same as Lou Gehrig's disease, and is also what Stephen Hawking had. It is a neurodegenerative disease, thought to mostly affect the motor neurons. Ryosuke Oki, et al, "Efficacy and Safety of Ultrahigh-Dose Methylcobalamin in Early-Stage Amyotrophic Lateral Sclerosis" JAMA Neurol. 2022;
jade_s
in
Pernicious Anaemia Society
9 months ago
😢 postpartum mental health
Evening everyone, I'm so sorry for posting. I desperately need to 'talk'. I have been in tears every night for the past few weeks. I am in tears as we speak. Has anyone had any struggles with postpartum depression? I've struggled massively with it - twice. I have been so poorly at one point several
Evening everyone, I'm so sorry for posting. I desperately need to 'talk'. I have been in tears every night for the past few weeks. I am in tears as we speak. Has anyone had any struggles with postpartum depression? I've struggled massively with it - twice. I have been so poorly at one point several
Positive2022
in
Pregnancy and Parenting Support
1 year ago
Intraductal Carcinoma & Cribiform pattern 4 treatment options?
Newly dx. PCa. with Intraductal carcinoma, IDC-P. This is the most aggressive prostate cancer type. In my case 4+3 with 70% pattern 4 with cribriform which make it even more worse. There are four types of pattern 4 (poorly formed glands, glomeruloid structures, cribriform glands, and fused glands) and
Newly dx. PCa. with Intraductal carcinoma, IDC-P. This is the most aggressive prostate cancer type. In my case 4+3 with 70% pattern 4 with cribriform which make it even more worse. There are four types of pattern 4 (poorly formed glands, glomeruloid structures, cribriform glands, and fused glands) and
FMOH_N
in
Advanced Prostate Cancer
9 months ago
Low-dose Aspirin.
I imagine that the new aspirin study [JAMA (1)] will get a lot of media play, but I will post anyway. A previous study concluded that the only people who benefit from low-dose aspirin are those who have already experienced a cardiovascular event. For everyone else, the risks obliterate any benefit
I imagine that the new aspirin study [JAMA (1)] will get a lot of media play, but I will post anyway. A previous study concluded that the only people who benefit from low-dose aspirin are those who have already experienced a cardiovascular event. For everyone else, the risks obliterate any benefit
pca2004
in
Fight Prostate Cancer
10 months ago
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