Experiences with

Chorionic villus sampling (CVS)

After 5 months on Acala twice a day and having just finished my Obin infusions, my lymphocyte count is now 3.6, down from 280 before my treatment began. Obin killed my leukemia cells so fast at the beginning I got hospitalized for 36 hours with TLS as my kidneys were overwhelmed with dead cancer cells

I was just advised by my vascular surgery team that CLL greatly increases your risk of blood clots hence the need for a surgical intervention. I am just in the process of researching this further and was wondering if this community could shed further light on this for me. thanks

Following on from the interesting discussion on testing for 17p del and TP53 disruption/mutations I thought it might be worth posting this paper which sets out how this testing and analysis is done. It's published by ERIC, the European Research Initiative on CLL, and is the 2024 update of the last

Following 12 months of rising lymphocytes I’ve just had confirmation that I’ve got CLL. Not great news but genetic tests are encouraging, so I’m low risk watch and wait at this time. This comes after 21 years of living with another form of blood cancer, Essential Thrombocythaemia (ET for short). That

Did a 'deep dive' on Lymphatic Drainage. What kept cross-referencing was rebounding. So, I got in the market for a mini-trampoline, then decided to 'go full send', committed to an annual membership at a trampoline park. Forget the dogma, 'this is for kids'. Usually there when kids are in school,

Hi from Australia! i have joined this forum after searching for alternative treatments to chemo for my dad (83) CLL 8 years on. I am very open minded with a slight bias against chemo after watching my mum suffer and pass from breast cancer. So not wanting my dad to have chemo unless it’s a last resort

Could hypopharynx fullness be related to a typical progression of cll or a possible richters transformation? TIA

Hi all Diagnosed since this past June. Started on Brukinsa due to 6mm Supraclavicular node. Tolerating well on reduced dose of 240mg. I have a Notch 1 mutation and a normal FISH. No one has ever mentioned this mutation to me and was afraid to ask. Can anyone give me information on this. Also negative

Mike Peters from a Welsh music band The Alarm had CLL for 29 years but was diagnosed with a Richters transformation this year. He received treatment in the UK STELLAR trial which adds Acalabrutinib to the usual R-CHOP chemotherapy. He's had a spectacular response and his story is here http://digitaleditions.telegraph.co.uk

Hi AllI have had chemo for high grade B cell and Richters Cll. In remission for 2 years but now regressed with nodes in 3 areas. Am on Watch Wait to see how fast growth is. They say possibility of an inhibitor drug called Zanubrutamide if growth of Richters gets faster. Googled drug but says

I’ve had CLL B cell for 16 years. I had a great Oncologist but she moved 11/2 years ago so she used to do bone marrow biopsies to check my CLL. My new oncologist does pet scans but as far as I know that just checks for the Lymphoma part off CLl. If I have no tumors she says my cancer isn’t active. But

I learned that I am IGHV mutated / TP53 unmutated, then received the following additional results without much commentary. Is anybody able to help interpret them? - Chromosome Microarray Analysis (CMA) was performed on this bone marrow sample using 8x60K oligonucleotide arrays (Agilent) to screen for

Original article citation: Tedeschi, A., Frustaci, A. M., Condoluci, A., Coscia, M., Chiarle, R., Zinzani, P. L., Motta, M., Gaidano, G., Quaresmini, G., Scarfò, L., Catania, G., Deodato, M., Jones, R., Tabanelli, V., Griggio, V., Stüssi, G., Calleri, A., Pini, K., Cairoli, R., Zenz, T., … Montillo

Has anyone done preimplantation generic screening test. I'm 40 years old and my IVF journey started 2 year ago. I have been through two IVF cycles, a total 3 transfers (one fresh & two FETs). The last one was done on 4th Nov and I found a positive result on 14th. However, it turned negative the following

I am 74 and in CLL remission after a 24-month course of Venetoclax plus Rituximab completed in September 2023. In July 2023 I was diagnosed with low grade, non-muscle invasive (PTa) bladder cancer and had a 12-month treatment with Epirubicin per respective protocol. Although biopsies at 3-month intervals

hi all, I’ve just had a worrying call from the hospital following 12 week screening results. We have 1:50 chance for Down syndrome. I am 40. NT was 1.9. HCG was normal. The main abnormality was my HEPP-A was low at 0.3. We’ve been given the options of a CVS now or Amnio at 15 weeks. I don’t know

I’ve only just found out that Pregnacare conception max, that I used for ages, contains Biotin, which can affect blood hormone readings when you have tests for things like thyroid function, and even AMH! So they can make your TSH look lower and AMH look lower (and even HCG appear lower, and its in Pregnacare

Good evening I had FET on the 24th Oct and a positive pregnancy test 9 days later, however I also had some negative tests with some cheap brands. I had bloods taken 12 days post transfer and the HCG was 30. 48 hours later I had another blood test (14 days post FET) and this was 60. I’m due to

Hi, I’ve surprisingly had a positive pregnancy test following my third cycle of letrozole (first and only time I’ve responded to letrozole). Feeling very surprised, shocked and happy. I’m day 17 post trigger shot / day 16 post ovulation. I told my fertility clinic Friday of the positive test and

hi all please keep my daughter in your thoughts today as she is 6 weeks today post FET transfer. Had spotting over a few days but nothing too heavy. Strong positive with hcg of 18000. We are off to the scan today for some reassurance. Petrified for her.