Search
Search
About
Log in
Join
Experiences with
Castration
Posts
Communities
1,150 public posts
Filter results
Testosterone.
Huggins basically got his Nobel Prize for discovering that
castration
could be used to treat PCa. Giving the impression that T is dangerous stuff. {Well, T is a pussycat compared to estradiol [E2] - women reading this, feel free to chime in.
Huggins basically got his Nobel Prize for discovering that
castration
could be used to treat PCa. Giving the impression that T is dangerous stuff. {Well, T is a pussycat compared to estradiol [E2] - women reading this, feel free to chime in.
pjoshea13
in
Advanced Prostate Cancer
5 years ago
Castration sensitive vs castate resistant
My husbands PSA became resistant to Casodex/Lupron but he is currently responding to Enzalutamide/ Lupron. Does this mean he qualifies as hormone sensitive or as hormone resistant?
My husbands PSA became resistant to Casodex/Lupron but he is currently responding to Enzalutamide/ Lupron. Does this mean he qualifies as hormone sensitive or as hormone resistant?
Blair77
in
Advanced Prostate Cancer
6 years ago
Androgen Receptor Splice Variant 7 and Hormone Therapy Resistance in High-Risk Castration-Resistant Prostate Cancer
Journal of Clinical Oncology Prospective Multicenter Validation of Androgen Receptor Splice Variant 7 and Hormone Therapy Resistance in High-Risk
Castration
-Resistant Prostate Cancer: The PROPHECY Study J. Clin.
Journal of Clinical Oncology Prospective Multicenter Validation of Androgen Receptor Splice Variant 7 and Hormone Therapy Resistance in High-Risk
Castration
-Resistant Prostate Cancer: The PROPHECY Study J. Clin.
Balsam01
in
Advanced Prostate Cancer
5 years ago
Want to take advantage of all our features? Just log in!
Log in
or
Join
LATITUDE Study - final survival analysis
[Epub ahead of print] Abiraterone acetate plus prednisone in patients with newly diagnosed high-risk metastatic
castration
-sensitive prostate cancer (LATITUDE): final overall survival analysis of a randomised, double-blind, phase 3 trial.
[Epub ahead of print] Abiraterone acetate plus prednisone in patients with newly diagnosed high-risk metastatic
castration
-sensitive prostate cancer (LATITUDE): final overall survival analysis of a randomised, double-blind, phase 3 trial.
pjoshea13
in
Advanced Prostate Cancer
5 years ago
Improved Response to Olaparib Treatment Among Men With mCRPC Harboring BRCA1/2 vs ATM Mutations
Access this abstract now BACKGROUND Poly ADP-ribose polymerase (PARP) inhibitors, such as olaparib, are being explored as a treatment option for metastatic
castration
-resistant prostate cancer (mCRPC) in men harboring mutations in homologous recombination DNA-repair genes.
Access this abstract now BACKGROUND Poly ADP-ribose polymerase (PARP) inhibitors, such as olaparib, are being explored as a treatment option for metastatic
castration
-resistant prostate cancer (mCRPC) in men harboring mutations in homologous recombination DNA-repair genes.
Balsam01
in
Advanced Prostate Cancer
5 years ago
Reaching the final destiny on my life's journey
Lived over seven years with
Castration
Resistance Prostate Cancer ( CSPC) and pain. Running out of options. Started refusing treatments. I put up a good fight, losing it now. Looking for hospice or other short ways out. No joy left to continue the fight for. Bob
Lived over seven years with
Castration
Resistance Prostate Cancer ( CSPC) and pain. Running out of options. Started refusing treatments. I put up a good fight, losing it now. Looking for hospice or other short ways out. No joy left to continue the fight for. Bob
bboby
in
Advanced Prostate Cancer
6 years ago
Patient-Reported Outcomes Following Enzalutamide or Placebo in Men With Nonmetastatic, Castration-Resistant Prostate Cancer
•Enzalutamide has clinical benefit in men with high-risk, nonmetastatic
castration
-resistant prostate cancer, and this treatment option should be discussed with patients.
•Enzalutamide has clinical benefit in men with high-risk, nonmetastatic
castration
-resistant prostate cancer, and this treatment option should be discussed with patients.
Balsam01
in
Advanced Prostate Cancer
5 years ago
Opko Health PII trial of SARM and ADT
ADT results in the reduction of testosterone to
castration
levels in men with prostate cancer. However, ADT is associated with side effects such as decreased LBM, physical function, bone quality and increases in body fat, frailty and hot flashes.
ADT results in the reduction of testosterone to
castration
levels in men with prostate cancer. However, ADT is associated with side effects such as decreased LBM, physical function, bone quality and increases in body fat, frailty and hot flashes.
AZjame
in
Advanced Prostate Cancer
6 years ago
When Is Enough Enough???
In this time he has gone through
castration
, 50 rounds of radiation (various areas), multiple chemotherapy (Taxotere, Xtandi, Radium 223, Jevtana and now back on Taxotere again.
In this time he has gone through
castration
, 50 rounds of radiation (various areas), multiple chemotherapy (Taxotere, Xtandi, Radium 223, Jevtana and now back on Taxotere again.
Jashelby
in
Advanced Prostate Cancer
6 years ago
immunotherapy combo worked in 25% of asymptomatic and minimally symptomatic patients who progressed after second-generation hormonal therapy
Really good news: The combination of nivolumab (Opdivo) plus ipilimumab (Yervoy) demonstrated activity in a biomarker-enriched population of patients with metastatic
castration
-resistant prostate cancer (mCRPC); however, researchers need to refine the toxicity profile, said Sumit K.
Really good news: The combination of nivolumab (Opdivo) plus ipilimumab (Yervoy) demonstrated activity in a biomarker-enriched population of patients with metastatic
castration
-resistant prostate cancer (mCRPC); however, researchers need to refine the toxicity profile, said Sumit K.
George71
in
Advanced Prostate Cancer
5 years ago
Stereotactic Radiotherapy for oligoprogressive CRPC.
[Epub ahead of print] Metastasis-directed stereotactic radiotherapy for oligoprogressive
castration
-resistant prostate cancer: a multicenter study.
[Epub ahead of print] Metastasis-directed stereotactic radiotherapy for oligoprogressive
castration
-resistant prostate cancer: a multicenter study.
pjoshea13
in
Advanced Prostate Cancer
5 years ago
new systemic drugs extend overall survival for mCRPC by 6 months.
Impact of new systemic therapies on overall survival of patients with metastatic
castration
-resistant prostate cancer in a hospital-based registry. https://www.ncbi.nlm.nih.gov/pubmed/30643173
Impact of new systemic therapies on overall survival of patients with metastatic
castration
-resistant prostate cancer in a hospital-based registry. https://www.ncbi.nlm.nih.gov/pubmed/30643173
George71
in
Advanced Prostate Cancer
6 years ago
Darolutamide in Nonmetastatic, Castration-Resistant Prostate Cancer
From Practice Update. I would appreciate some feedback as to whether the members have already seen these articles that I post from Practice Update. I assume most people already subscribe to Practice Update? I don't want to unnecessarily waste bandwidth. https://www.practiceupdate.com/C/79887/56
From Practice Update. I would appreciate some feedback as to whether the members have already seen these articles that I post from Practice Update. I assume most people already subscribe to Practice Update? I don't want to unnecessarily waste bandwidth. https://www.practiceupdate.com/C/79887/56
Balsam01
in
Advanced Prostate Cancer
5 years ago
Niraparib - The GALAHAD study (NCT02854436).
“These preliminary results suggest that PARP inhibition with niraparib may play an important role in the treatment of men with metastatic
castration
-resistant prostate cancer who have mutations in DNA repair genes,” Matthew R.
“These preliminary results suggest that PARP inhibition with niraparib may play an important role in the treatment of men with metastatic
castration
-resistant prostate cancer who have mutations in DNA repair genes,” Matthew R.
pjoshea13
in
Advanced Prostate Cancer
5 years ago
Tumor Cholesterol Synthesis
"Perturbations in cholesterol homeostasis appear to be maintained even when PCa approaches the advanced, '
castration
-resistant' state. Overall, this provides a link between cholesterol accumulation and PCa cell growth.
"Perturbations in cholesterol homeostasis appear to be maintained even when PCa approaches the advanced, '
castration
-resistant' state. Overall, this provides a link between cholesterol accumulation and PCa cell growth.
pjoshea13
in
Advanced Prostate Cancer
5 years ago
Exceptional Response to 177-Lutetium PSMA in Prostate Cancer Harboring DNA Repair Defects
clinical cancer informatics Get Topic Alerts TAKE-HOME MESSAGE •This case study reports an exceptional response to 177lutetium PSMA in a patient with metastatic
castration
-resistant
clinical cancer informatics Get Topic Alerts TAKE-HOME MESSAGE •This case study reports an exceptional response to 177lutetium PSMA in a patient with metastatic
castration
-resistant
Balsam01
in
Advanced Prostate Cancer
5 years ago
Vitamin D and Testosterone Co-ordinately Modulate Intracellular Zinc Levels and Energy Metabolism in Prostate Cancer Cells.
Seven days after
castration
, the rats were treated with vehicle (control) or 1,25 D for 3 weeks and then sacrificed. ...
Seven days after
castration
, the rats were treated with vehicle (control) or 1,25 D for 3 weeks and then sacrificed. ...
pjoshea13
in
Advanced Prostate Cancer
6 years ago
Germline Testing for Men With Prostate Cancer
For example, olaparib was given Breakthrough Therapy designation by the US Food and Drug Administration for BRCA1/2- or ATM-positive metastatic
castration
-resistant prostate cancer (mCRPC) on the basis of the TOPARP-A trial demonstrating improved responses particularly in patients with DNA repair mutations
For example, olaparib was given Breakthrough Therapy designation by the US Food and Drug Administration for BRCA1/2- or ATM-positive metastatic
castration
-resistant prostate cancer (mCRPC) on the basis of the TOPARP-A trial demonstrating improved responses particularly in patients with DNA repair mutations
Balsam01
in
Advanced Prostate Cancer
5 years ago
Worried about my father
In
Castration
resistance the can PSA drop 2 points in a month? What is the treatment at
castration
stage?
In
Castration
resistance the can PSA drop 2 points in a month? What is the treatment at
castration
stage?
Hidden
in
Advanced Prostate Cancer
6 years ago
Adding Erleada (apalutamide) to first-line ADT significantly extended survival and delayed disease progression.
Article here: https://prostatecancernewstoday.com/2019/02/04/erleada-improves-survival-metastatic-
castration
-sensitive-prostate-cancer/?utm_medium=desktop-push-notification&utm_source=Notifications&utm_campaign=OneSignal
Article here: https://prostatecancernewstoday.com/2019/02/04/erleada-improves-survival-metastatic-
castration
-sensitive-prostate-cancer/?utm_medium=desktop-push-notification&utm_source=Notifications&utm_campaign=OneSignal
Moespy
in
Advanced Prostate Cancer
6 years ago
1
...
43
44
45
...
58
Next page
10
20
30
40
50
Filter results
Clear filters
Posted in
All communities
Advanced Prostate Cancer
1024 results
Fight Prostate Cancer
70 results
Prostate Cancer Network
25 results
View top 10 communities
Sort by
Most Relevant
Newest