FYI... Good news update for this drug in ongoing Phase 3 TITAN Trial. Article here:
Adding Erleada (apalutamide) to first... - Advanced Prostate...
Adding Erleada (apalutamide) to first-line ADT significantly extended survival and delayed disease progression.
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Thank you very much Moespy, great article
Thanks for posting, Moespy... let the arsenal grow.... kill the beast...
I printed it. Thanks
I have read several articles on this trial and the reported results. I have no idea where this will lead, but apalutamide added to a first line ADT may offer many of us a tremendous. I look forward to the posting of many additional comments as more information becomes available.
I believe I would try this treatment now if I could either get in a trial or convince my MO to put me on such a drug combination. It sounds superior to the multitude of different treatments many of you have been through.
Best thoughts to everyone.
Hi Twoofus,
I saw you mentioned clinical trials in your reply (this drug not yet available from doctors). The link below will take you to a list of trials involving apalutamide. Each trial has a list of criteria for inclusion. You can use the criteria and the margin check boxes to narrow down what might be of interest and pursue if desired.
Best wishes!
You have to have metastases and not be castration-resistent according to the TITAN study to use Erleada.
Thanks GP24.
Many current clinical trials utilizing apalutamide for castrate resistant also. I believe they are hoping this will be one of the drugs that can be used on both ends of castrate.
Here is a list that includes those trials (same link as my reply above to Twoofus):
Would xtandi be just as effective in in this scenario, even without the adt. Who knows? Rocco
Definitely not an expert at interpreting what I find on the subject but here is what I think I understand. Xtandi is for metastatic and apalutamide is for non-metastatic both to be used in conjunction with ADT in castrate resisitant condition. I believe that is why apalutamide is a first line defender and xtandi is a second line. Might be in over my head but I believe that is the current state of these meds.
Definitely not an expert at interpreting what I find on the subject but here is what I think I understand. Xtandi is for metastatic and apalutamide is for non-metastatic both to be used in conjunction with ADT in castrate resisitant condition. I believe that is why apalutamide is a first line defender and xtandi is a second line. Might be in over my head but I believe that is the current state of these meds.