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Colorectal Cancer Biomarkers and Treatment Impact - If you are ever diagnosed with colon cancer ....
Do you know how your biomarker testing results can impact your colorectal cancer treatment? There are many biomarkers that are important in colorectal cancer and its treatment. We have created an overview of the most important information about each biomarker to help you. This chart has a short description
Do you know how your biomarker testing results can impact your colorectal cancer treatment? There are many biomarkers that are important in colorectal cancer and its treatment. We have created an overview of the most important information about each biomarker to help you. This chart has a short description
GCCA-Survivor
Administrator
in
Colon Cancer Connected
2 months ago
At the crossroads (again)
My profile is up to date, but, briefly, have failed chemo, ADT (am castrate resistant), failed Keytruda and now Pluvicto. Scans yest. & today show progression along with PSA rise. All my mets are in bone. So, my SOC choices are cabazataxel or radium 223. Other options are trial, which are a crapshoot
My profile is up to date, but, briefly, have failed chemo, ADT (am castrate resistant), failed Keytruda and now Pluvicto. Scans yest. & today show progression along with PSA rise. All my mets are in bone. So, my SOC choices are cabazataxel or radium 223. Other options are trial, which are a crapshoot
rsgdmd
in
Advanced Prostate Cancer
5 months ago
Plant Virus Fights Breast Cancer (similar to Prostate Cancer) in Mice With 'Widespread Effectiveness
Plant Virus Fights Breast Cancer (similar to Prostate Cancer) in Mice With 'Widespread Effectiveness Https://www.sciencealert.com/plant-virus-fights-cancers-in-mice-with-widespread-effectiveness Nanoparticles harvested from the cowpea mosaic virus boosted survival rates and systemically suppressed
Plant Virus Fights Breast Cancer (similar to Prostate Cancer) in Mice With 'Widespread Effectiveness Https://www.sciencealert.com/plant-virus-fights-cancers-in-mice-with-widespread-effectiveness Nanoparticles harvested from the cowpea mosaic virus boosted survival rates and systemically suppressed
cesanon
in
Advanced Prostate Cancer
2 months ago
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New technique modifies T-Cells to cure cancer
"Importantly, we have seen large numbers of multi-pronged T-cells in the
blood
of
cancer
survivors," says Sewell. "To date, we have not found such multi-pronged T-cells in people where cancer progresses."
"Importantly, we have seen large numbers of multi-pronged T-cells in the
blood
of
cancer
survivors," says Sewell. "To date, we have not found such multi-pronged T-cells in people where cancer progresses."
Derf4223
in
Advanced Prostate Cancer
1 year ago
Niraparib
I was diagnosed with Stage 3c high grade serous ovarian cancer in June 2023 which had spread to omentum and peritoneal lining. I had ascites which was drained twice and have developed a pleural effusion. I had the 3xchemo and debulking surgery then 3 more chemo. Finished treatment on Dec 23. ca-125
I was diagnosed with Stage 3c high grade serous ovarian cancer in June 2023 which had spread to omentum and peritoneal lining. I had ascites which was drained twice and have developed a pleural effusion. I had the 3xchemo and debulking surgery then 3 more chemo. Finished treatment on Dec 23. ca-125
Berryporridgr
in
My Ovacome
5 months ago
My Cancer Journey Repost
It's time for a repost of my two-part cancer journey diary. Some "starting the journey readers" might find it helpful. Originally posted as two Health Unlocked "replies" - maybe I should make them an actual full "post". So I am pleased to report that
other than fatigue, I feel sort of normal right
It's time for a repost of my two-part cancer journey diary. Some "starting the journey readers" might find it helpful. Originally posted as two Health Unlocked "replies" - maybe I should make them an actual full "post". So I am pleased to report that
other than fatigue, I feel sort of normal right
JohnInTheMiddle
in
Advanced Prostate Cancer
2 months ago
Pain Management
Dear All can anyone help. Diagnosed with stage 1V advanced metastatic prostate cancer December 2022. 6 sessions of Chemo, then Firmagon and Nubeqa PSA was 349 now about 1 but has been increasing. Cancer was in most bones but no organs - primarily pelvis and hips - have had radiation treatment but still
Dear All can anyone help. Diagnosed with stage 1V advanced metastatic prostate cancer December 2022. 6 sessions of Chemo, then Firmagon and Nubeqa PSA was 349 now about 1 but has been increasing. Cancer was in most bones but no organs - primarily pelvis and hips - have had radiation treatment but still
Nyon
in
Advanced Prostate Cancer
5 months ago
Treatment stopped
We thought Erlotinib was working for my dad, his tumour had reduced significantly on October scan ( started on drug Aug 23) but Jan scan showed growth, cough back and has been getting steadily worse with weight down to 7 stone ,diarrhoea and debilitating fatigue. Although Oncologist thought a standard
We thought Erlotinib was working for my dad, his tumour had reduced significantly on October scan ( started on drug Aug 23) but Jan scan showed growth, cough back and has been getting steadily worse with weight down to 7 stone ,diarrhoea and debilitating fatigue. Although Oncologist thought a standard
Adaughter
in
The Roy Castle Lung Cancer Foundation
5 months ago
Beaconthecat
Diagnosed last April thru a lymph node biopsy....results SLL...currently on W&W...a few more nodes have emerged but feel good, no symptoms, exercise hard and just living life...
Diagnosed last April thru a lymph node biopsy....results SLL...currently on W&W...a few more nodes have emerged but feel good, no symptoms, exercise hard and just living life...
Beaconthecat
in
CLL Support
5 months ago
Failed Pluvicto
Hello warriors, especially Tall Allen. I'm going on 6 years since Gleason 9 advanced metastatic diagnosis. Had a good run on Zytiga and all the usual other treatments, but just failed last ditch treatment of Pluvicto (after treatment 3). Did genetic testing and no significant mutations. My PSA is
Hello warriors, especially Tall Allen. I'm going on 6 years since Gleason 9 advanced metastatic diagnosis. Had a good run on Zytiga and all the usual other treatments, but just failed last ditch treatment of Pluvicto (after treatment 3). Did genetic testing and no significant mutations. My PSA is
jersy
in
Advanced Prostate Cancer
5 months ago
BLA for Subcutaneous Nivolumab Accepted by the FDA for Advanced/Metastatic Solid Tumors
A biologics license application (BLA) has been accepted by the FDA seeking approval of nivolumab (Opdivo) co-formulated with Halozyme’s proprietary recombinant human hyaluronidase (rHuPH20; subcutaneous nivolumab) for adult patients with solid tumors eligible for previously approved nivolumab indications
A biologics license application (BLA) has been accepted by the FDA seeking approval of nivolumab (Opdivo) co-formulated with Halozyme’s proprietary recombinant human hyaluronidase (rHuPH20; subcutaneous nivolumab) for adult patients with solid tumors eligible for previously approved nivolumab indications
God_Loves_Me
in
Advanced Prostate Cancer
2 months ago
Some Reference Material - NECP/SCCP
-----
I am constantly updating this post as I come across additional relevant material.
----- Emerging Insights in Small-Cell Carcinoma of the Genitourinary Tract: From Diagnosis to Novel Therapeutic Horizons, 2024 https://ascopubs.org/doi/10.1200/EDBK_430336#:~:text=Small%2Dcell%20carcinoma
-----
I am constantly updating this post as I come across additional relevant material.
----- Emerging Insights in Small-Cell Carcinoma of the Genitourinary Tract: From Diagnosis to Novel Therapeutic Horizons, 2024 https://ascopubs.org/doi/10.1200/EDBK_430336#:~:text=Small%2Dcell%20carcinoma
skiingfiend
in
Advanced Prostate Cancer
5 months ago
PSA relapse rate vs testosterone nadir - 3
This plot shows the PSA relapse rate after RT and ADT, for Intermediate and High Risk men, comparing different levels of testosterone nadir ( 50 nd/dL). (ref: 2019) The
best
outcomes
are significantly associated with a
lower testosterone nadir ( < 20 ng/dL),
and the relationship
This plot shows the PSA relapse rate after RT and ADT, for Intermediate and High Risk men, comparing different levels of testosterone nadir ( 50 nd/dL). (ref: 2019) The
best
outcomes
are significantly associated with a
lower testosterone nadir ( < 20 ng/dL),
and the relationship
janebob99
in
Advanced Prostate Cancer
5 months ago
Testosterone back to normal
I was diagnosed with PC last April 2023 with PSA of 125. Darilutimide and Relogolix, along with HIIT, plant based diet, and various supplements brought it down to .006. My MO granted a holiday about 6-7 weeks ago, and yesterday, I had my testosterone score. It is back to 312, which is above the number
I was diagnosed with PC last April 2023 with PSA of 125. Darilutimide and Relogolix, along with HIIT, plant based diet, and various supplements brought it down to .006. My MO granted a holiday about 6-7 weeks ago, and yesterday, I had my testosterone score. It is back to 312, which is above the number
Cape1
in
Advanced Prostate Cancer
5 months ago
Triplet and now Radiation?
Hi all - just wanting your thoughts on this. In my profile you would see full details but I will summarize here. 50yr old diagnosed Aug 2nd with PCA with spread to L5 and pubic bone. Original PSA was around 9 and put on Casodex for month, then Lupron every 3 months, plus Darolutamide. Just completed
Hi all - just wanting your thoughts on this. In my profile you would see full details but I will summarize here. 50yr old diagnosed Aug 2nd with PCA with spread to L5 and pubic bone. Original PSA was around 9 and put on Casodex for month, then Lupron every 3 months, plus Darolutamide. Just completed
Yzinger
in
Advanced Prostate Cancer
5 months ago
No more enzalutamide: docetaxel next up
So enzalutamide has stopped doing its thing. PSA up to 3.9 but it’s worked for 3.5 years. Also got a new lesion in my thoracic spine so in addition to docetaxel, a single dose of radiotherapy. Hope that will all be underway within a couple of weeks. Some fear for a while about the meds not working and
So enzalutamide has stopped doing its thing. PSA up to 3.9 but it’s worked for 3.5 years. Also got a new lesion in my thoracic spine so in addition to docetaxel, a single dose of radiotherapy. Hope that will all be underway within a couple of weeks. Some fear for a while about the meds not working and
FortyWinks
in
Advanced Prostate Cancer
5 months ago
Carboplatin alternatives
I was diagnosed with Primary Peritoneal high grade serous cancer stage 3C in early 2021. I had 6 cycles of Carboplatin and Paclitaxel, radical surgery, two more chemo cycles then Niraparib for just over a year until it stopped working and my CA125 began to rise rapidly. Surgery was considered and
I was diagnosed with Primary Peritoneal high grade serous cancer stage 3C in early 2021. I had 6 cycles of Carboplatin and Paclitaxel, radical surgery, two more chemo cycles then Niraparib for just over a year until it stopped working and my CA125 began to rise rapidly. Surgery was considered and
Alice77
in
My Ovacome
5 months ago
Warren Farr
Hi, my name is warren I was diagnosed in late November 2023 with Prostrate Cancer from a MRI I then had a PSMA CT Scan and the next day Robotic removal of my prostrate RRP. The Biopsy showed staging pT3b 30% ductal after a Gleason score of 5+4=9 My PSA after removal was 0.22 then 4 weeks later 0.38
Hi, my name is warren I was diagnosed in late November 2023 with Prostrate Cancer from a MRI I then had a PSMA CT Scan and the next day Robotic removal of my prostrate RRP. The Biopsy showed staging pT3b 30% ductal after a Gleason score of 5+4=9 My PSA after removal was 0.22 then 4 weeks later 0.38
Snoopy8125
in
Advanced Prostate Cancer
5 months ago
Should go into the OMAHA2a ODM-208 (MK-5684-004): phase 3 trial?
I had my 3 monthly OC visit last week. Blood test is showing 0.3 up from 0.15 six weeks ago. MO is suggesting that I should go into the ODM-208 (MK-5684): phase 3 trial if PSA rises above 1.0. PSA of 1.0 or above is a entry requirement for the trial, presumable to be sure that my current treatment
I had my 3 monthly OC visit last week. Blood test is showing 0.3 up from 0.15 six weeks ago. MO is suggesting that I should go into the ODM-208 (MK-5684): phase 3 trial if PSA rises above 1.0. PSA of 1.0 or above is a entry requirement for the trial, presumable to be sure that my current treatment
LakeT
in
Advanced Prostate Cancer
3 months ago
Testosterone Levels and Prostate Cancer Risk - 1
This plot shows the association of baseline testosterone levels with PCa aggressiveness. For example, if you have low aggressive PCA, your testosterone is likely to be Normal. But, if you have metastatic PCa, your testosterone is likely to be very Low. This shows that having normal testosterone
This plot shows the association of baseline testosterone levels with PCa aggressiveness. For example, if you have low aggressive PCA, your testosterone is likely to be Normal. But, if you have metastatic PCa, your testosterone is likely to be very Low. This shows that having normal testosterone
janebob99
in
Advanced Prostate Cancer
5 months ago
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