Niraparib

[Berryporridgr]

I was diagnosed with Stage 3c high grade serous ovarian cancer in June 2023 which had spread to omentum and peritoneal lining. I had ascites which was drained twice and have developed a pleural effusion.

I had the 3xchemo and debulking surgery then 3 more chemo. Finished treatment on Dec 23.

ca-125 34. I have been put on Niraparib as brca and hrd neg. I had a NED scan in Jan.

But after 1 month of being on Niraparib my ca125 is at 86. I have burning pains in my sides and abdomen. I apparently still have a slight pleural effusion.

I am being sent for a ct-scan. Has anyone else had this quick rise in ca125 and it not be a recurrence? And is there any long term survivors with the same type of scenario as mine? Feeling petrified that all has returned so soon.

Thanks

[Cheka123]

i ha..ve the same thing after one month on nirparib i was so sick and discovered recurrance ...i am on chemo again for 9 rounds i just not sure about anything ...they said no to maintance drug for me...and have given me little hope i am feeling much better tho...after two rounds of chemo i been told it has advance