Experiences with

Besremi

There’s a side effect of Besremi that we now found. I remember having a bit of Incontinence and my pee stunk as long as I was on Besremi. My newest US shows that I now have 2 cysts on my left kidney which I haven’t had before the Besremi.

SURPASS-ET trial compared effectiveness of anagrelide with Besremi for ET patients. Besremi was more effective in reducing allele burden and controlling blood counts. Hopefully Besremi will be approved soon as a first-line treatment for ET.

Due to declining hgb and very part spleen, I decided to try Besremi. I just completed my 6th dose of Besremi, last dose was 150 q 2 weeks. I have had symptoms of long bone pain and bone pain in toes and fingers.

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My MPN specialist has talked to me about switching to Besremi. I also have JAK2 and ASXL1 mutations. I understand the benefits of switching to Besremi.

A few times a year it suits me (PV) better to take my bi-weekly besremi-shot (200mg) (also 3 days a week 1 capsule HU 500) one day earlier or later then the fixed rhythm. Anyone knowledge or opinion if this has a (big) impact on the overall working-process of besremi? Thanks!

I have been on besremi for almost 2 years. I have PV and ET. My AB at its highest was 58 it is now 25. I am wondering if others are able to reduce besremi or if anyone has reduced their AB to zero. Does that mean you no longer have PV?

WHAT IS THE MW OF THE PEG USED IN BESREMI?

Finally got my first script for Besremi. It took a while and a lot of hoops for my MPN specialist to jump through to get temp approval to move from Peg to Besremi given the global shortage of Peg.

My concern is that Crohn’s is usually an autoimmune problem and I really don’t want to stop Besremi as this is controlling my PV. Does anyone have Crohn’s but been able to continue with Pegasys/Besremi? Thanks Paul

Mam pytanie do osób stosujących besremi w postaci pena. Jak używacie igły? Wciskacie ja na pena czy nakręcacie ? message from Maz, I have translated this question (using Google): I have a question for those using besremi in pen form. How do you use the needle?

due to the global shortage of Pegasus I have been moved temporarily onto besremi . The side effects of fatigue have hit me like a train . I had no fatigue in Pegasus . Has any one else experienced this and if they have was it temporary .

s office told me they are switching me to Jakofi because Besremi was making my liver enzymes too high and not controling my red blood cell numbers at a lower dose. I knew Besremi was known to cause liver enzymes to increase, but it looks like Jakofi can cause liver enzyme increases as well.

I have been on Besremi since May 2023, but only on the full 500 mcg dose of Besremi since June 2024. My platelets responded very quickly from 1.1M to between 200 and 300k within 6 months of starting the Besremi. However, my HCT has been very stubborn.

Hi I have been on besremi for 18 months and my hematocrit is finally becoming controlled. Has anyone gone down to monthly shots? Has anyone been able to track their mutation frequency?

Since started Besremi in early 2023 my JAK2 has gone from 51.89% to 13.17% I hadn’t realized that drops in hematocrit and WBC could potentially indicate progression to myelofibrosis. I’m hopeful that these numbers will start to climb after reducing my Besremi dose.

Hi all, I started off with Besremi 2 weeks ago. My inital dose was 50mcg and from now on for the time being I am supposed to take 100 mcg every two weeks. I was wondering now if its ok to take the 3rd dose from my first pen.

Hallo zusammen Wie sind eure Erfahrungen mit Besremi? Bitte eure Erfahrungen mit mir teilen! Danke vielmals☺️

My question is, has anyone gone through BESREMI to the 500mcg and still had symptoms? Did you switch to JAKAFI? Did it help?

) and was 21.59 with no venesections in this period so I was really pleased with the result Fingers crossed improvements will continue with Besremi