Besremi shot earlier or later then fixed rhythm

[nemo731]

A few times a year it suits me (PV) better to take my bi-weekly besremi-shot (200mg) (also 3 days a week 1 capsule HU 500) one day earlier or later then the fixed rhythm. Anyone knowledge or opinion if this has a (big) impact on the overall working-process of besremi? Thanks!

[hunter5582]

It is best to keep on pattern to ensure the most stable level of Besremi in your system. There is some flexibility in this though, Besremi has a half life of approximately 7 days. This means that on day 14 you are down to about 25% of Besremi in your system. While it is likely not a major concern to be a day early or late, it is not the optimal dosing strategy. Suggest that you review your question with a MPN Specialist for the best case specific answer.

[nemo731 in reply to hunter5582]

thanks for clear/balanced reaction...