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palliative radiation treatment questions
In my prior (first) post, I shared about my 82 year old father’s condition. Thanks for all the helpful and thoughtful responses from this community. He has gone off Goserelin (ADT) injection and now just on bicalutamide pills. As his testosterone seems to have returned, he’s now having more energy
In my prior (first) post, I shared about my 82 year old father’s condition. Thanks for all the helpful and thoughtful responses from this community. He has gone off Goserelin (ADT) injection and now just on bicalutamide pills. As his testosterone seems to have returned, he’s now having more energy
running_kiwi
in
Advanced Prostate Cancer
2 months ago
PSA rockets up to 344
Hello - I received quite shocking news during my visit to the Mayo Clinic last week. My PSA has jumped to 344 from a low of 3.6 last November, when I completed chemo with cabazitaxel. PSA did start to rise quite soon, into double digits, but this is by far my highest PSA ever. Dr. Kwon recommended
Hello - I received quite shocking news during my visit to the Mayo Clinic last week. My PSA has jumped to 344 from a low of 3.6 last November, when I completed chemo with cabazitaxel. PSA did start to rise quite soon, into double digits, but this is by far my highest PSA ever. Dr. Kwon recommended
Arcticfox44
in
Advanced Prostate Cancer
4 months ago
Kishan's 6 month Androgen Annihilation Therapy Study for metastatic PCa
https://x.com/prostatecell/status/1770206641813696808?s=46 https://bit.ly/43rr68x seems to be a promising tactic for oligometastatic PCa, that combines SBRT with an ADT mix . The Abstract starts off by noting that with metastatic hormone sensitive PCa, recurrence almost always happens within six months
https://x.com/prostatecell/status/1770206641813696808?s=46 https://bit.ly/43rr68x seems to be a promising tactic for oligometastatic PCa, that combines SBRT with an ADT mix . The Abstract starts off by noting that with metastatic hormone sensitive PCa, recurrence almost always happens within six months
Xavier10
in
Advanced Prostate Cancer
4 months ago
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Xtandi and Intermittent
I started Xtandi 2 months ago and got PSA undetectable. <.001. Now, my doctor suggest me to reduce from 4 tablets per say to 3 tablets per day. A month ago, I say "no", reasoning that reduction of the amount may create an early resistance to Xtandi. But he is persistent. He said no necessarily.
I started Xtandi 2 months ago and got PSA undetectable. <.001. Now, my doctor suggest me to reduce from 4 tablets per say to 3 tablets per day. A month ago, I say "no", reasoning that reduction of the amount may create an early resistance to Xtandi. But he is persistent. He said no necessarily.
Domas
in
Advanced Prostate Cancer
2 months ago
Information on extandi or enzalutamide
Hello fellow warriors I've been on extandi for about a year and a half to two years I had to go off of it this year because I was having stomach's problems from it but if my PSA goes back up I'll end up getting back on it again there is some side effects from a extandi but drinking lots of water seems
Hello fellow warriors I've been on extandi for about a year and a half to two years I had to go off of it this year because I was having stomach's problems from it but if my PSA goes back up I'll end up getting back on it again there is some side effects from a extandi but drinking lots of water seems
Startanew
in
Advanced Prostate Cancer
2 months ago
Deescalated 225Ac-PSMA-617 Versus 177Lu/225Ac-PSMA-617 Cocktail Therapy: A Single-Center Retrospective Analysis of 233 Patients, July 2024
Here is a summary article on the research from the Society of Nuclear Medicine & Molecular Imaging the July Issue of The Journal of Nuclear Medicine. (The full research paper is also linked below.) From the paper abstract: [i]The aim of this work is to evaluate our clinical real-world data obtained
Here is a summary article on the research from the Society of Nuclear Medicine & Molecular Imaging the July Issue of The Journal of Nuclear Medicine. (The full research paper is also linked below.) From the paper abstract: [i]The aim of this work is to evaluate our clinical real-world data obtained
cujoe
in
Fight Prostate Cancer
2 months ago
Zytiga vs Nubeqa for Triple Therapy
Hi, I've recently received a diagnosis of Stage 4 prostate cancer, which is high volume and hormone-sensitive. I've consulted with 3 oncologist and all recommend triple therapy: Lupron alongside 6 rounds of Docetaxel, plus an ARPI. While two oncologists recommend Nubeqa, one strongly advocates for Zytiga
Hi, I've recently received a diagnosis of Stage 4 prostate cancer, which is high volume and hormone-sensitive. I've consulted with 3 oncologist and all recommend triple therapy: Lupron alongside 6 rounds of Docetaxel, plus an ARPI. While two oncologists recommend Nubeqa, one strongly advocates for Zytiga
littleCar
in
Advanced Prostate Cancer
6 months ago
Very low psa with new bone mets
Hello I'm looking for some answers and information for a member of my family. He was diagnosed 4 years ago with oligometastatic pca,went through radiation, adt+abirateron and chemo. In some point abirateron has failed so went for chemo,one year later when psa is still low as 0.014 new bone metastases
Hello I'm looking for some answers and information for a member of my family. He was diagnosed 4 years ago with oligometastatic pca,went through radiation, adt+abirateron and chemo. In some point abirateron has failed so went for chemo,one year later when psa is still low as 0.014 new bone metastases
Niso
in
Advanced Prostate Cancer
2 months ago
Could This Alternative Regiment Be Decelerating My PSA?
Between Summer of 2021 and Summer of 2023--two solid years--my PSA went from 11.5 to 15.3, roughly two points per year. Having concern about my PSA, I ventured into a more "aggressive anti-prostate cancer diet," centered around legumes/black, purple, wild rices/walnuts/flaxseed/tomato paste
Between Summer of 2021 and Summer of 2023--two solid years--my PSA went from 11.5 to 15.3, roughly two points per year. Having concern about my PSA, I ventured into a more "aggressive anti-prostate cancer diet," centered around legumes/black, purple, wild rices/walnuts/flaxseed/tomato paste
back2health
in
Advanced Prostate Cancer
4 months ago
Dad’s 6 weekly psa shows a little rise compared to the one at 3 weeks - grateful for any thoughts.
Dad , 83 , was diagnosed in May with PSA 18 and bone mets as per PSMA scan. Initially the plan was to do lupron and he was started on bicalutamide 100 mg daily , which he took for 3 weeks uptil 7th June. But then we decided to go with relugolix and not lupron and the bicalutamide was stopped.
Dad , 83 , was diagnosed in May with PSA 18 and bone mets as per PSMA scan. Initially the plan was to do lupron and he was started on bicalutamide 100 mg daily , which he took for 3 weeks uptil 7th June. But then we decided to go with relugolix and not lupron and the bicalutamide was stopped.
Tinkudi
in
Advanced Prostate Cancer
2 months ago
Prostate cancer cases worldwide likely to double by 2040, analysis finds
Hopefully this report leads to more investment in treatment . "The number of men diagnosed with prostate cancer worldwide is projected to double to 2.9 million a year by 2040, with annual deaths predicted to rise by 85%, according to the largest study of its kind. " "Prostate cancer is already a
Hopefully this report leads to more investment in treatment . "The number of men diagnosed with prostate cancer worldwide is projected to double to 2.9 million a year by 2040, with annual deaths predicted to rise by 85%, according to the largest study of its kind. " "Prostate cancer is already a
PSAed
in
Advanced Prostate Cancer
6 months ago
Does taking chemo upfront reduce chances of the cancer morphing into more aggressive variants in the future ?
My PSA at diagnosis was relatively low at 21 and scans showed multiple bone mets. My oncologist said that puts me at a greater risk of the cancer morphing Into a more aggressive one in the future compared to someone who had come with a psa of 400-500. Is this correct ? Would doing chemotherapy
My PSA at diagnosis was relatively low at 21 and scans showed multiple bone mets. My oncologist said that puts me at a greater risk of the cancer morphing Into a more aggressive one in the future compared to someone who had come with a psa of 400-500. Is this correct ? Would doing chemotherapy
Simpson80
in
Advanced Prostate Cancer
2 months ago
new member
Hello, I am here because my husband just got diagnosed with prostate cancer with metastasis to lymph nodes. Gleason 9, PSA 56, he is 54 years old. We are both in shock still and real scared. Did not expect to hear stage 4. Trying to get as much info as possible how to deal with this new reality. He was
Hello, I am here because my husband just got diagnosed with prostate cancer with metastasis to lymph nodes. Gleason 9, PSA 56, he is 54 years old. We are both in shock still and real scared. Did not expect to hear stage 4. Trying to get as much info as possible how to deal with this new reality. He was
Orange95
in
Advanced Prostate Cancer
2 months ago
Why don't doctors prescribe Dutasteride more often?
I get this question from a lot of men that have prostate cancer. Although the black label warning is a concern to some doctors, and has been discussed here in previous posts, I think the main reason is simply that most doctors don't know about it. Here is the single best paper reviewing the three major
I get this question from a lot of men that have prostate cancer. Although the black label warning is a concern to some doctors, and has been discussed here in previous posts, I think the main reason is simply that most doctors don't know about it. Here is the single best paper reviewing the three major
janebob99
in
Prostate Cancer Network
6 months ago
4 month ADT holiday
I’ve been given 4 months ADT holiday with no treatment Then more blood tests to see how things are going. I was finding it hard to concentrate when reading as I was so tired. I’m already feeling more awake after 2 days of stopping Abiraterone and my balance seems to be improving. Doing some gym work
I’ve been given 4 months ADT holiday with no treatment Then more blood tests to see how things are going. I was finding it hard to concentrate when reading as I was so tired. I’m already feeling more awake after 2 days of stopping Abiraterone and my balance seems to be improving. Doing some gym work
Rob11111
in
Advanced Prostate Cancer
2 months ago
PSA rising after salvage RT. What next?
My PSA is low but on the rise. <.006 in January and .042 now. I'm not on ADT. See bio for history. I hate to stand on the sidelines and watch it rise. Is there something I can do, or do I have to wait until PSA rises then have a scan? What is SOC? Your comments are appreciated.
My PSA is low but on the rise. <.006 in January and .042 now. I'm not on ADT. See bio for history. I hate to stand on the sidelines and watch it rise. Is there something I can do, or do I have to wait until PSA rises then have a scan? What is SOC? Your comments are appreciated.
SCreader
in
Advanced Prostate Cancer
2 months ago
PSMA Scans and False Positives
So I saw my MO yesterday to review my ongoing treatment of Xtandi and Lupron. Been 3 months so far with no real side effects except hot flashes. My PSMA scan showed prostate and one met to sacrum. Prostate treated with 28 rounds of EBRT. MO says since sacrum is so close to prostrate it might have
So I saw my MO yesterday to review my ongoing treatment of Xtandi and Lupron. Been 3 months so far with no real side effects except hot flashes. My PSMA scan showed prostate and one met to sacrum. Prostate treated with 28 rounds of EBRT. MO says since sacrum is so close to prostrate it might have
Jeffdanger
in
Advanced Prostate Cancer
6 months ago
Best alternative PET for PSMA negative PCa
Asking for a friend. He was diagnosed 3 years ago with high risk high volume (Gleason 3+5) PCa. Treated with EBRT + LDRBT + ADT (18 months). His PSA was undetectable but is now rising (3+) but PSMA-PET was negative, even in the prostate - implying PSMA non-avid cancer. What would be the best non-PSMA
Asking for a friend. He was diagnosed 3 years ago with high risk high volume (Gleason 3+5) PCa. Treated with EBRT + LDRBT + ADT (18 months). His PSA was undetectable but is now rising (3+) but PSMA-PET was negative, even in the prostate - implying PSMA non-avid cancer. What would be the best non-PSMA
Vynbal
in
Advanced Prostate Cancer
4 months ago
Reaction to docetaxel twice now.
second cycle of docetaxel and the same reaction. Pelvic pain, flushing, muzzy head and head ache. Great response from the team again and feeling better pretty quickly. Last time they tried again and it went through okay. Had meds to mitigate but not prevented a reaction. They aren’t go to try the infusion
second cycle of docetaxel and the same reaction. Pelvic pain, flushing, muzzy head and head ache. Great response from the team again and feeling better pretty quickly. Last time they tried again and it went through okay. Had meds to mitigate but not prevented a reaction. They aren’t go to try the infusion
FortyWinks
in
Advanced Prostate Cancer
6 months ago
Lutetium at earlier stage, clinical trial is enrolling
The second trial provides men with metastatic prostate cancer access to prostate-specific membrane antigen (PSMA)-targeted therapy prior to chemotherapy. Currently, PSMA-targeted therapy is only available after chemotherapy. However, phase III clinical trials have shown that PSMA-targeted therapies are
The second trial provides men with metastatic prostate cancer access to prostate-specific membrane antigen (PSMA)-targeted therapy prior to chemotherapy. Currently, PSMA-targeted therapy is only available after chemotherapy. However, phase III clinical trials have shown that PSMA-targeted therapies are
Maxone73
in
Advanced Prostate Cancer
6 months ago
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