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Benign prostatic hyperplasia
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Studies help explain why some prostate cancers become resistant to hormone therapy
https://www.sciencedaily.com/releases/2023/12/231204135037.htm
https://www.sciencedaily.com/releases/2023/12/231204135037.htm
zeitgeistxx
in
Advanced Prostate Cancer
5 months ago
Avodart and Flomax
Hello brothers. Is it safe to use Avodart and Flomax with advanced prostate cáncer? I am tired of getting up to pee 7 or 8 times a night.
Hello brothers. Is it safe to use Avodart and Flomax with advanced prostate cáncer? I am tired of getting up to pee 7 or 8 times a night.
CountryJoe
in
Advanced Prostate Cancer
5 months ago
updated scans post chemo
My dad has done 2 rounds of chemo, the third was delayed by hospitalization for sepsis. He has also had 10 rounds of radiation. His third round will be near Christmas and they completed scans to compare to his pre chemo scans. His full body bone scans state the following “Diffuse skeletal metastatic
My dad has done 2 rounds of chemo, the third was delayed by hospitalization for sepsis. He has also had 10 rounds of radiation. His third round will be near Christmas and they completed scans to compare to his pre chemo scans. His full body bone scans state the following “Diffuse skeletal metastatic
StayingSTRNG
in
Advanced Prostate Cancer
5 months ago
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Lupron and prostate cancer
hi everyone. im a 67 year old man taking Lupron hormone deprivation for prostate cancer. i finished receiving 20 external beam radiation treatments in August 2023. the Lupron injections are quarterly and will continue for 18-24 months. my interest in sex has completely dropped off. i assume this is normal
hi everyone. im a 67 year old man taking Lupron hormone deprivation for prostate cancer. i finished receiving 20 external beam radiation treatments in August 2023. the Lupron injections are quarterly and will continue for 18-24 months. my interest in sex has completely dropped off. i assume this is normal
rolex1951
in
Advanced Prostate Cancer
5 months ago
IS THIS A PATTERN???? Thoughts and helpful ideas to guide a path
Diagnosed Gleason 9 advanced, PSA 19, mets in pelvis(maybe more???)Had 6 x chemo ,5 X radio to prostate, ADT through out.PSA was down to 0.08 at one point.1 MARCH23 0.29 25 MAY23 0.08 NOV23 0.12 05 DEC23 0.25 12 FEB24 0.44 started feeling bouts of unreasonable tiredness, think maybe active cancer???
Diagnosed Gleason 9 advanced, PSA 19, mets in pelvis(maybe more???)Had 6 x chemo ,5 X radio to prostate, ADT through out.PSA was down to 0.08 at one point.1 MARCH23 0.29 25 MAY23 0.08 NOV23 0.12 05 DEC23 0.25 12 FEB24 0.44 started feeling bouts of unreasonable tiredness, think maybe active cancer???
Mrtroxely
in
Advanced Prostate Cancer
3 months ago
Is there seasonality to testosterone levels?
My ADT treatments (Lupron/Abiraterone/Prednisone) ended on May 02 2023 at which point both my PSA and Testosterone were flat lined. Here are the results of the four times I have been tested since the end of the ADT. * Aug 18 2023: PSA is 0.09, Testosterone is 3.3 nmol/l (95.2 ng/dL), Testosterone
My ADT treatments (Lupron/Abiraterone/Prednisone) ended on May 02 2023 at which point both my PSA and Testosterone were flat lined. Here are the results of the four times I have been tested since the end of the ADT. * Aug 18 2023: PSA is 0.09, Testosterone is 3.3 nmol/l (95.2 ng/dL), Testosterone
Mascouche
in
Advanced Prostate Cancer
3 months ago
18F-flotufolastat PET alters treatment approach for nearly 90% of patients with recurrent prostate cancer
"18F-flotufolastat is approved by the FDA for use in patients with suspected prostate cancer metastasis who are potentially curable by definitive surgery or radiation, and patients with suspected prostate cancer recurrence based on elevated PSA levels." https://www.urologytimes.com/view/18f-flotufolastat-pet-alters-treatment-approach-for-nearly
"18F-flotufolastat is approved by the FDA for use in patients with suspected prostate cancer metastasis who are potentially curable by definitive surgery or radiation, and patients with suspected prostate cancer recurrence based on elevated PSA levels." https://www.urologytimes.com/view/18f-flotufolastat-pet-alters-treatment-approach-for-nearly
Maxone73
in
Advanced Prostate Cancer
3 months ago
PSMA PET Looks Good But PSA Rising
Hello, I am hoping someone can help us understand what we might be missing prior to meeting with MO this week. My husband was diagnosed with metastatic prostate cancer with mets to pelvic lymph node and a few spots in bones in early January 2022 at 56 years old. He was successfully treated with Triplet
Hello, I am hoping someone can help us understand what we might be missing prior to meeting with MO this week. My husband was diagnosed with metastatic prostate cancer with mets to pelvic lymph node and a few spots in bones in early January 2022 at 56 years old. He was successfully treated with Triplet
FaithOverFear104
in
Advanced Prostate Cancer
3 months ago
Failed RP & SRT; Negative PSMA PET
Greetings. I had a radical prostatectomy that failed and then salvage radiation therapy that appears to have failed as well. A recent PSMA PET scan showed no signs of recurrent prostate cancer or metastases. By way of background: NOV 2010 - Dx at age 52; positive DRE, Gleason 3+3, PSA 5.0; prostate
Greetings. I had a radical prostatectomy that failed and then salvage radiation therapy that appears to have failed as well. A recent PSMA PET scan showed no signs of recurrent prostate cancer or metastases. By way of background: NOV 2010 - Dx at age 52; positive DRE, Gleason 3+3, PSA 5.0; prostate
dans_journey
in
Advanced Prostate Cancer
3 months ago
225Ac-J591 Yields Responses in Difficult-to-Treat Metastatic Prostate Cancer
It seems to work better on visceral and bone metastatis... https://www.cancertherapyadvisor.com/home/news/conference-coverage/suo-2023/225ac-j591-yields-responses-in-difficult-to-treat-metastatic-prostate-cancer/
It seems to work better on visceral and bone metastatis... https://www.cancertherapyadvisor.com/home/news/conference-coverage/suo-2023/225ac-j591-yields-responses-in-difficult-to-treat-metastatic-prostate-cancer/
Maxone73
in
Advanced Prostate Cancer
5 months ago
Recurrence after prostatectomy
I have a relative who had surgery 6.5 years ago. Pathology was very favorable, 3+3+tertiary 4 i.e. less than 5%, no pos margins, no ECE, no nodes. He remained undetectable for 6.5 years, but now is .07 verified. What would SOC be for him? Prostate bed or wide radiation, length of ADT, just Lupron or
I have a relative who had surgery 6.5 years ago. Pathology was very favorable, 3+3+tertiary 4 i.e. less than 5%, no pos margins, no ECE, no nodes. He remained undetectable for 6.5 years, but now is .07 verified. What would SOC be for him? Prostate bed or wide radiation, length of ADT, just Lupron or
Fred312
in
Advanced Prostate Cancer
5 months ago
Proteolysis-Targeting Chimeras (PROTACs): targeting cancer by deleting deleterious proteins?
There seem to be a kind of superiority of PROTACs over conventional inhibitors in treating prostate cancer. The article examines various targets for PROTACs in prostate cancer, including the androgen receptor and other critical oncoproteins, while addressing future prospects and challenges in this
There seem to be a kind of superiority of PROTACs over conventional inhibitors in treating prostate cancer. The article examines various targets for PROTACs in prostate cancer, including the androgen receptor and other critical oncoproteins, while addressing future prospects and challenges in this
Maxone73
in
Advanced Prostate Cancer
6 months ago
Which treatment option best for recurrent oligo?
In addition to SBRT for the two mets that make me join the happy recurrent crowd, what would be my best treatment option? I have had no SOC medication for 2.5 years. My T is 4 European scale 110 US scale. 1 Only ADT for seven months. This is what MO recommends, besides SBRT, since stronger/longer
In addition to SBRT for the two mets that make me join the happy recurrent crowd, what would be my best treatment option? I have had no SOC medication for 2.5 years. My T is 4 European scale 110 US scale. 1 Only ADT for seven months. This is what MO recommends, besides SBRT, since stronger/longer
Purple-Bike
in
Advanced Prostate Cancer
3 months ago
PSA update
DX Nov 2020. PSA 960 high volume metastatic. Lowest PSA nadir 0.1 Aug 2022. Slowly rising Nov. 2023 was 0.21, Feb 2024 0.41....Doubling time 3.1 months . On Lupron and 1000 mg Abiraterone with 0.5 Dexamethasone . Darn.
DX Nov 2020. PSA 960 high volume metastatic. Lowest PSA nadir 0.1 Aug 2022. Slowly rising Nov. 2023 was 0.21, Feb 2024 0.41....Doubling time 3.1 months . On Lupron and 1000 mg Abiraterone with 0.5 Dexamethasone . Darn.
wolverine11
in
Advanced Prostate Cancer
3 months ago
Pluvicto still working well
Am coming to my fifth injection and I see I neglected to post my results after #3 & #4 so they are here, too. So far: Aug 16: PSA
99.7
Aug 21: Pluvicto
#1
Sep 11: PSA
106
Sep 28: PSA
91.8
Oct 05: Pluvicto
#2
Oct 25: PSA
57.8
Nov
Am coming to my fifth injection and I see I neglected to post my results after #3 & #4 so they are here, too. So far: Aug 16: PSA
99.7
Aug 21: Pluvicto
#1
Sep 11: PSA
106
Sep 28: PSA
91.8
Oct 05: Pluvicto
#2
Oct 25: PSA
57.8
Nov
Miccoman
in
Advanced Prostate Cancer
3 months ago
Rising PSA
Year 7… No prostate. Clear everything in 2017 … but 6 months after surgery rising PSA. Casodex/Lupron/39 Rounds Radiation. Presently on Lupron/Nubeqa PSA rising PSMA Scan Clear CT scan with Contrast today plus Fractionated Blood Biopsy. PSA 10.8 Waiting on CT results but Dr. Aggarwal wants
Year 7… No prostate. Clear everything in 2017 … but 6 months after surgery rising PSA. Casodex/Lupron/39 Rounds Radiation. Presently on Lupron/Nubeqa PSA rising PSMA Scan Clear CT scan with Contrast today plus Fractionated Blood Biopsy. PSA 10.8 Waiting on CT results but Dr. Aggarwal wants
JolleySprings
in
Advanced Prostate Cancer
3 months ago
Rising PSA on ADT
Prostatectomy 2015, Gleason 4 + 3. 31 external radiation tx, ADT (Zoladex) 2015-17, post nadir Oct 2017 rising PSA until Jan 2022. Degarelix for 8 months. Two months after end of Degarelix PSA rising rapidly (doubling time 5 weeks). Started ADT (Zoladex) Feb 2023. By Oct PSA 0.40 ug/L, Dec 0.43 ug
Prostatectomy 2015, Gleason 4 + 3. 31 external radiation tx, ADT (Zoladex) 2015-17, post nadir Oct 2017 rising PSA until Jan 2022. Degarelix for 8 months. Two months after end of Degarelix PSA rising rapidly (doubling time 5 weeks). Started ADT (Zoladex) Feb 2023. By Oct PSA 0.40 ug/L, Dec 0.43 ug
MGBman
in
Advanced Prostate Cancer
3 months ago
Is a false-positive biopsy possible?
I have a history of prostate cancer in my family. My father had it, and my brother had it and he had his prostate removed. As a result, for the last 13 years, I've had my PSA checked every six months. I typically run a very low PSA, historically .5 or .6. About 18 months ago I noticed that my PSA was
I have a history of prostate cancer in my family. My father had it, and my brother had it and he had his prostate removed. As a result, for the last 13 years, I've had my PSA checked every six months. I typically run a very low PSA, historically .5 or .6. About 18 months ago I noticed that my PSA was
CBRD
in
Advanced Prostate Cancer
3 months ago
Casadex, on and off
I was on Casadex close to 3 years. During the last part of going on 3 years my psa started rising. They took me off Casadex and put me on Orgovyx which did not work so they put me on injections of lupron once a month. My psa again started rising on lupron injections. Now They have put me on nubeqa to
I was on Casadex close to 3 years. During the last part of going on 3 years my psa started rising. They took me off Casadex and put me on Orgovyx which did not work so they put me on injections of lupron once a month. My psa again started rising on lupron injections. Now They have put me on nubeqa to
woppaho
in
Advanced Prostate Cancer
3 months ago
Stage 4, GL 9 seeking advice
After 10 months without pain, I'm starting to have pain in my back. Orgovyx and Zytiga have appeared to keep the cancer relatively quiet until now. Next month I turn 87. I'm quite healthy, apart from Prostate cancer. I have no illusions about a cure but would like to have as many QOL days as possible
After 10 months without pain, I'm starting to have pain in my back. Orgovyx and Zytiga have appeared to keep the cancer relatively quiet until now. Next month I turn 87. I'm quite healthy, apart from Prostate cancer. I have no illusions about a cure but would like to have as many QOL days as possible
Poollover
in
Advanced Prostate Cancer
1 day ago
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