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Apomorphine

Has anyone taken apomorphine sublingual and is it expensive. Thanks
Has anyone taken apomorphine sublingual and is it expensive. Thanks
cshamb
in Parkinson's Movement

Apomorphine pump; does anyone have any experience?

His blood pressure is normal and I understand if we were to consider it he will have to undertake a Apomorphine Challenge to estimate his tolerance but otherwise I am much in the dark as to what it entails. Any experience good or bad would be greatly appreciated.
His blood pressure is normal and I understand if we were to consider it he will have to undertake a Apomorphine Challenge to estimate his tolerance but otherwise I am much in the dark as to what it entails. Any experience good or bad would be greatly appreciated.
novagayfox
in Multiple System Atrophy Trust

How does Apokyn help PD?

I see it's apomorphine. I've used apomorphine in my veterinary practice for nearly 40 years. It's my drug of choice for poisoning cases. I get it in 5mg tabs. For a dog who ate a large bag of Halloween chocolate kisses I'd press one tab under the upper eyelid.
I see it's apomorphine. I've used apomorphine in my veterinary practice for nearly 40 years. It's my drug of choice for poisoning cases. I get it in 5mg tabs. For a dog who ate a large bag of Halloween chocolate kisses I'd press one tab under the upper eyelid.
kaypeeoh
in Parkinson's Movement
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medication only works for 30/40 mins

., washed down with hot water. it seems to get into my system within 30/40 mins after taking but then within a hour it has worn off. it doesn't matter if i take 50mg 100mg or 150mg it just wears off the same. my neurologist has had me on all sorts even the apomorphine pump im only 39 diagnosed 4yrs
., washed down with hot water. it seems to get into my system within 30/40 mins after taking but then within a hour it has worn off. it doesn't matter if i take 50mg 100mg or 150mg it just wears off the same. my neurologist has had me on all sorts even the apomorphine pump im only 39 diagnosed 4yrs
Todd-pw
in Parkinson's Movement

Apomophine

Has anyone tried Kybmnobi (Apomorphine) and what is he cost. Thank you
Has anyone tried Kybmnobi (Apomorphine) and what is he cost. Thank you
cshamb
in Parkinson's Movement

Sublingual Apomorphine approved by FDA

https://www.apdaparkinson.org/article/new-medication-approved-by-fda-for-off-symptoms/
https://www.apdaparkinson.org/article/new-medication-approved-by-fda-for-off-symptoms/
pdpatient
in Parkinson's Movement

Anyone currently using apomorphine pumps "full time"?

I am trying to find someone currently using apomorphine pump 20+/- hours a day. I started using my on low dosage about 8/10 hours a day, after 2.5 months told to increase 9am to 5am. Between midnight it is set to half dosage until 5am then I can remove it until 9am when it starts up again.
I am trying to find someone currently using apomorphine pump 20+/- hours a day. I started using my on low dosage about 8/10 hours a day, after 2.5 months told to increase 9am to 5am. Between midnight it is set to half dosage until 5am then I can remove it until 9am when it starts up again.
Baalbek
in Parkinson's Movement

Is anyone familiar with a prescription drug called Kynmobi? (apomorphine HCL) Sublingual film.

My neuro/motion specialist introduced me last week. It's specifically for off time, especially for those on heavy duty C/L products. I must say it's better than the C/L pill for off time he had me on all this time!
My neuro/motion specialist introduced me last week. It's specifically for off time, especially for those on heavy duty C/L products. I must say it's better than the C/L pill for off time he had me on all this time!
mgregor6
in Parkinson's Movement

APL-130277 still without FDA Approval: Why?

Apomorphine is a somewhat strange Dopamine Agonist (non-egoline DA Parky B!) that required subcutaneous injections. It certainly hasn't been a mainline DA prescription in the USA.
Apomorphine is a somewhat strange Dopamine Agonist (non-egoline DA Parky B!) that required subcutaneous injections. It certainly hasn't been a mainline DA prescription in the USA.
sharoncrayn
in Parkinson's Movement

Losing hope

I recently had a hosptial trial with apomorphine - with out success. I had the first classic PD symptoms a year ago after falling off a ladder. Now 80% of the time i'm a stooped, shuffling, juddering wreck and for much of that 80% i can't move at all.
I recently had a hosptial trial with apomorphine - with out success. I had the first classic PD symptoms a year ago after falling off a ladder. Now 80% of the time i'm a stooped, shuffling, juddering wreck and for much of that 80% i can't move at all.
pen1
in Parkinson's Movement

Watch video - FYI

(pasted that portion of the paper) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5516582/ Subcutaneous apomorphine injection and infusion Modern clinical experience of using apomorphine subcutaneous injection for treating PD can be traced back to 1951 when the drug was shown to have a major potential
(pasted that portion of the paper) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5516582/ Subcutaneous apomorphine injection and infusion Modern clinical experience of using apomorphine subcutaneous injection for treating PD can be traced back to 1951 when the drug was shown to have a major potential
John_morris71
in Parkinson's Movement

are you aware about the drug "Apomorphine" being introduced in India by an UK based Brittannia Pharmacuticals, King's College London today?

hi, everyone, Today one M/s Vijaya Group of hospitals ( www.vijayahospital.org) is starting to market for the benefit of Chenaites NON ORAL treatment for Parkinsons to be administered through APO-PEN & APO-PUMP manufactured by research team King's College LONDON. made by one BRITANNIA PHARMACEUTICALS
hi, everyone, Today one M/s Vijaya Group of hospitals ( www.vijayahospital.org) is starting to market for the benefit of Chenaites NON ORAL treatment for Parkinsons to be administered through APO-PEN & APO-PUMP manufactured by research team King's College LONDON. made by one BRITANNIA PHARMACEUTICALS
billiards
in Parkinson's Movement

Apomorphine Benefits Finally Confirmed in Parkinson's

The benefits of the dopamine agonist apomorphine in Parkinson's disease have finally been confirmed in a randomized controlled trial, although the drug has been used in the condition for many years https://www.medscape.com/viewarticle/901709
The benefits of the dopamine agonist apomorphine in Parkinson's disease have finally been confirmed in a randomized controlled trial, although the drug has been used in the condition for many years https://www.medscape.com/viewarticle/901709
iqbaliqbal
in Parkinson's Movement

apomorphine

has anyone tried it?
has anyone tried it?
iqbaliqbal
in Parkinson's Movement

Apomorphine pump

I look after someone who has just been fitted with apomorphine pump. Has anyone had experience of one of these. Do they help the Parkinson’s?
I look after someone who has just been fitted with apomorphine pump. Has anyone had experience of one of these. Do they help the Parkinson’s?
Lindac03
in Care Community

Some good news

https://parkinsonsnewstoday.com/2018/06/27/sunovions-under-the-tongue-apomorphine-eases-parkinsons-off-periods-phase-3-trial-shows/?utm_source=PAR+E-mail+List&utm_campaign=0af5c78b09-RSS_WEEKLY_EMAIL_CAMPAIGN_DAILY_NON-US&utm_medium=email&utm_term=0_62dd4fb5e3-0af5c78b09-72859793
https://parkinsonsnewstoday.com/2018/06/27/sunovions-under-the-tongue-apomorphine-eases-parkinsons-off-periods-phase-3-trial-shows/?utm_source=PAR+E-mail+List&utm_campaign=0af5c78b09-RSS_WEEKLY_EMAIL_CAMPAIGN_DAILY_NON-US&utm_medium=email&utm_term=0_62dd4fb5e3-0af5c78b09-72859793
dadcor
in Parkinson's Movement

More good news from FDA

https://parkinsonsnewstoday.com/2018/04/04/sunovion-asks-fda-to-ok-below-the-tongue-apomorphine-for-parkinsons-off-periods/
https://parkinsonsnewstoday.com/2018/04/04/sunovion-asks-fda-to-ok-below-the-tongue-apomorphine-for-parkinsons-off-periods/
delboy381
in Parkinson's Movement

Phase 111: under tongue Apomorphine

https://www.michaeljfox.org/foundation/news-detail.php?drug-reverses-off-periods-in-phase-iii-trial
https://www.michaeljfox.org/foundation/news-detail.php?drug-reverses-off-periods-in-phase-iii-trial
Cbgs
in Parkinson's Movement

Apomorphine Sublingual Film Passes Phase lll Trial - New Option to Smooth "Off" Troughs

"Apomorphine, also known as APL-130277, works by mimicking dopamine’s activity in the brain. "Between 40 and 60 percent of Parkinson’s patients have ups and downs in their ability to control their movement.
"Apomorphine, also known as APL-130277, works by mimicking dopamine’s activity in the brain. "Between 40 and 60 percent of Parkinson’s patients have ups and downs in their ability to control their movement.
PDConscience
in Parkinson's Movement

Time for a PQQ thread (pyrroloquinoline quinone)

- "The apomorphine test using a rotameter has proved to be a popular test for screening the behavioral effects of a wide variety of lesions, drugs, and other experimental manipulations on the brain of rodents.
- "The apomorphine test using a rotameter has proved to be a popular test for screening the behavioral effects of a wide variety of lesions, drugs, and other experimental manipulations on the brain of rodents.
sunvox
in Parkinson's Movement
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