Experiences with

Apomorphine

Has anyone taken apomorphine sublingual and is it expensive. Thanks

His blood pressure is normal and I understand if we were to consider it he will have to undertake a Apomorphine Challenge to estimate his tolerance but otherwise I am much in the dark as to what it entails. Any experience good or bad would be greatly appreciated.

I see it's apomorphine. I've used apomorphine in my veterinary practice for nearly 40 years. It's my drug of choice for poisoning cases. I get it in 5mg tabs. For a dog who ate a large bag of Halloween chocolate kisses I'd press one tab under the upper eyelid.

., washed down with hot water. it seems to get into my system within 30/40 mins after taking but then within a hour it has worn off. it doesn't matter if i take 50mg 100mg or 150mg it just wears off the same. my neurologist has had me on all sorts even the apomorphine pump im only 39 diagnosed 4yrs

Has anyone tried Kybmnobi (Apomorphine) and what is he cost. Thank you

https://www.apdaparkinson.org/article/new-medication-approved-by-fda-for-off-symptoms/

I am trying to find someone currently using apomorphine pump 20+/- hours a day. I started using my on low dosage about 8/10 hours a day, after 2.5 months told to increase 9am to 5am. Between midnight it is set to half dosage until 5am then I can remove it until 9am when it starts up again.

My neuro/motion specialist introduced me last week. It's specifically for off time, especially for those on heavy duty C/L products. I must say it's better than the C/L pill for off time he had me on all this time!

Apomorphine is a somewhat strange Dopamine Agonist (non-egoline DA Parky B!) that required subcutaneous injections. It certainly hasn't been a mainline DA prescription in the USA.

I recently had a hosptial trial with apomorphine - with out success. I had the first classic PD symptoms a year ago after falling off a ladder. Now 80% of the time i'm a stooped, shuffling, juddering wreck and for much of that 80% i can't move at all.

(pasted that portion of the paper) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5516582/ Subcutaneous apomorphine injection and infusion Modern clinical experience of using apomorphine subcutaneous injection for treating PD can be traced back to 1951 when the drug was shown to have a major potential

hi, everyone, Today one M/s Vijaya Group of hospitals ( www.vijayahospital.org) is starting to market for the benefit of Chenaites NON ORAL treatment for Parkinsons to be administered through APO-PEN & APO-PUMP manufactured by research team King's College LONDON. made by one BRITANNIA PHARMACEUTICALS

The benefits of the dopamine agonist apomorphine in Parkinson's disease have finally been confirmed in a randomized controlled trial, although the drug has been used in the condition for many years https://www.medscape.com/viewarticle/901709

has anyone tried it?

I look after someone who has just been fitted with apomorphine pump. Has anyone had experience of one of these. Do they help the Parkinson’s?

https://parkinsonsnewstoday.com/2018/06/27/sunovions-under-the-tongue-apomorphine-eases-parkinsons-off-periods-phase-3-trial-shows/?utm_source=PAR+E-mail+List&utm_campaign=0af5c78b09-RSS_WEEKLY_EMAIL_CAMPAIGN_DAILY_NON-US&utm_medium=email&utm_term=0_62dd4fb5e3-0af5c78b09-72859793

https://parkinsonsnewstoday.com/2018/04/04/sunovion-asks-fda-to-ok-below-the-tongue-apomorphine-for-parkinsons-off-periods/

https://www.michaeljfox.org/foundation/news-detail.php?drug-reverses-off-periods-in-phase-iii-trial

"Apomorphine, also known as APL-130277, works by mimicking dopamine’s activity in the brain. "Between 40 and 60 percent of Parkinson’s patients have ups and downs in their ability to control their movement.

- "The apomorphine test using a rotameter has proved to be a popular test for screening the behavioral effects of a wide variety of lesions, drugs, and other experimental manipulations on the brain of rodents.