anybody late stage here that has been approved for sub-Q apomorphine (not opiates) self injections for dystonic storms? hang tough , cheers!
Any late stage PDer's.....: anybody late... - Cure Parkinson's
Any late stage PDer's.....
sorry double post ...yeeesh....just looking for fellow apo folks.......Apomorphine, sold under the brand name Apokyn among others, is a type of aporphine having activity as a non-selective dopamine agonist which activates both D2-like and, to a much lesser extent, D1-like receptors.[1] It also acts as an antagonist of 5-HT2 and α-adrenergic receptors with high affinity. The compound is historically a morphine decomposition product made by boiling morphine with concentrated acid, hence the -morphine suffix. Contrary to its name, apomorphine does not actually contain morphine or its skeleton, nor does it bind to opioid receptors. The apo- prefix relates to it being a morphine derivative ("[comes] from morphine").
Hubby used apomorphine for about a year and a half. He never had side effects. He just got tired of the injections. It helped him move better and speak clearly for 40 minutes or so about 10-15 minutes after injection. Because it worked so well, next week we are trying the new sublingual version, but it’s expensive.
I don’t know much about dystonia.