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Abiraterone
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Ipatasertib+abiraterone effective in men with PTEN-loss
A large Phase 3 trial found that ipatasertib combined with
abiraterone
significantly increased radiographic progression-free survival by 2 months in men who were previously untreated, metastatic and castration-resistant with PTEN loss.
A large Phase 3 trial found that ipatasertib combined with
abiraterone
significantly increased radiographic progression-free survival by 2 months in men who were previously untreated, metastatic and castration-resistant with PTEN loss.
Tall_Allen
in
Advanced Prostate Cancer
3 years ago
Latest PSA
I know a fast drop isn't always good news, but he started Casodex in December, Lupron (4 month) January, and
Abiraterone
March. So hoping a six month to 0.1 is actually good news. I'm happy for the time being. Should start Prostate Radiation soon, as his CT scan was June 25th.
I know a fast drop isn't always good news, but he started Casodex in December, Lupron (4 month) January, and
Abiraterone
March. So hoping a six month to 0.1 is actually good news. I'm happy for the time being. Should start Prostate Radiation soon, as his CT scan was June 25th.
JWPMP
in
Advanced Prostate Cancer
3 years ago
Advice needed on bone trauma
My skeleton is riddled with bone cancer, but since diagnosis December ’17 docetaxel,
abiraterone
and last Christmas, targeted radiotherapy on my prostate have kept things in check. However, two months ago I fell and badly bruised my left ribs, still twinging even now.
My skeleton is riddled with bone cancer, but since diagnosis December ’17 docetaxel,
abiraterone
and last Christmas, targeted radiotherapy on my prostate have kept things in check. However, two months ago I fell and badly bruised my left ribs, still twinging even now.
Tonyliv
in
Advanced Prostate Cancer
3 years ago
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And the superiority of Abiraterone before switching to Enalutamide (vs. the opposite sequence) Revisited.
dgcid=raven_sd_recommender_email Optimal sequencing of enzalutamide and
abiraterone
acetate plus prednisone in metastatic castration-resistant prostate cancer: a multicentre, randomised, open-label, phase 2, crossover trial Summary Background
Abiraterone
acetate plus prednisone and enzalutamide are both
dgcid=raven_sd_recommender_email Optimal sequencing of enzalutamide and
abiraterone
acetate plus prednisone in metastatic castration-resistant prostate cancer: a multicentre, randomised, open-label, phase 2, crossover trial Summary Background
Abiraterone
acetate plus prednisone and enzalutamide are both
MateoBeach
in
Advanced Prostate Cancer
3 years ago
Uva Ursi
I am less concerned about whether it will help, more concerned if there might be any interactions with Firmagon
abiraterone
and prednesone. So far I have found nothing online.
I am less concerned about whether it will help, more concerned if there might be any interactions with Firmagon
abiraterone
and prednesone. So far I have found nothing online.
spencoid2
in
Advanced Prostate Cancer
3 years ago
It’s NOT neuroendocrine or small cell!!!
Jeff was put on the oral medication
Abiraterone
(Zytiga) and Prednisone. In lieu of killing the cancer, they plan on starving it. Jeff’s hemoglobin is still dropping and is currently at 7.4. We’re nearing transfusion levels again. Jeff has “medium” fluid retention in his legs/ankles/feet.
Jeff was put on the oral medication
Abiraterone
(Zytiga) and Prednisone. In lieu of killing the cancer, they plan on starving it. Jeff’s hemoglobin is still dropping and is currently at 7.4. We’re nearing transfusion levels again. Jeff has “medium” fluid retention in his legs/ankles/feet.
Pancake_Lefse
in
Advanced Prostate Cancer
3 years ago
Repeat Please?
I am on firmagon,
abiraterone
and prednesone. My next shot is tomorrow. Today I feel great. I took my usual 3 mile bike ride to the mailbox.
I am on firmagon,
abiraterone
and prednesone. My next shot is tomorrow. Today I feel great. I took my usual 3 mile bike ride to the mailbox.
spencoid2
in
Advanced Prostate Cancer
3 years ago
Enzalutamide - Side Effects
He never had these side effects on other hormone blockade therapies over the years and on
Abiraterone
previously as well. Nervousness is listed as a common side effect with Enza. Does anybody have any insight into this? and any tips on how to mitigate it?
He never had these side effects on other hormone blockade therapies over the years and on
Abiraterone
previously as well. Nervousness is listed as a common side effect with Enza. Does anybody have any insight into this? and any tips on how to mitigate it?
taylor123
in
Advanced Prostate Cancer
3 years ago
Effect of ADT on Bicycling Speed and Power
Since I went on ADT (Orgovyx and
abiraterone
) my biking speed and power has substantially diminished. No surprise due to T=7. Hills I used to breeze right up are now challenging, and riding into any wind is very difficult.
Since I went on ADT (Orgovyx and
abiraterone
) my biking speed and power has substantially diminished. No surprise due to T=7. Hills I used to breeze right up are now challenging, and riding into any wind is very difficult.
rmarkley
in
Prostate Cancer Network
3 years ago
Input?
Bo says I am M1 CRPC (I am not really sure if this is really the case), and he suggested either
Abiraterone
, Enzalutamide, or Radium-233. Will also see Ohio State Dr. Min Yin July 21 to see what he thinks. Any thoughts? Thanks
Bo says I am M1 CRPC (I am not really sure if this is really the case), and he suggested either
Abiraterone
, Enzalutamide, or Radium-233. Will also see Ohio State Dr. Min Yin July 21 to see what he thinks. Any thoughts? Thanks
RunThru
in
Advanced Prostate Cancer
3 years ago
What could cause this rash?
I doubled the dose of
abiraterone
to 1000-mg early Sunday morning and woke up to this on my right arm. Tap on photo to see full extent of the rash. Doubled prednisone to 5-mg. starting Sunday as well. By Monday it had spread to the left side of my face and the top of both legs.
I doubled the dose of
abiraterone
to 1000-mg early Sunday morning and woke up to this on my right arm. Tap on photo to see full extent of the rash. Doubled prednisone to 5-mg. starting Sunday as well. By Monday it had spread to the left side of my face and the top of both legs.
tallguy2
in
Advanced Prostate Cancer
3 years ago
Clinical Trials in France for Prostate Cancer
My husband has been on
Abiraterone
since December 2019, but his psa has been steadily rising over the past few months, with a quadrupling of the figures in the last 3 months.
My husband has been on
Abiraterone
since December 2019, but his psa has been steadily rising over the past few months, with a quadrupling of the figures in the last 3 months.
Nellienoodle
in
Advanced Prostate Cancer
3 years ago
Ipatasertib/Abiraterone Data Published in Lancet Underscore the Combo’s Frontline Potential in PTEN-Loss mCRPC
https://www.onclive.com/view/ipatasertib-
abiraterone
-data-published-in-lancet-underscore-the-combo-s-frontline-potential-in-pten-loss-mcrpc George
https://www.onclive.com/view/ipatasertib-
abiraterone
-data-published-in-lancet-underscore-the-combo-s-frontline-potential-in-pten-loss-mcrpc George
NOCanceros
in
Advanced Prostate Cancer
3 years ago
The C-reactive protein-albumin ratio [CAR]
[u]patients with CAR > 0.5 has significantly shorter CSS than those with CAR ≤ 0.5 in
abiraterone
(median of 23 vs 49 months ...) and enzalutamide (median of 23 vs 41 months[/u] ...)" Quite a big difference. What does "prognostic" mean?
[u]patients with CAR > 0.5 has significantly shorter CSS than those with CAR ≤ 0.5 in
abiraterone
(median of 23 vs 49 months ...) and enzalutamide (median of 23 vs 41 months[/u] ...)" Quite a big difference. What does "prognostic" mean?
pjoshea13
in
Advanced Prostate Cancer
3 years ago
Most likely radiation schedule
Will reevaluate after 6th chemo, but likely course is adding
abiraterone
or enzalutamide, and radiation to prostate. We are both still working and live by our calendars. We can relocate to Rochester, MN and work remotely if necessary but it would be great to plan for possible scenarios.
Will reevaluate after 6th chemo, but likely course is adding
abiraterone
or enzalutamide, and radiation to prostate. We are both still working and live by our calendars. We can relocate to Rochester, MN and work remotely if necessary but it would be great to plan for possible scenarios.
leebeth
in
Advanced Prostate Cancer
3 years ago
Abiraterone or Zytiga and Excessive Gas. I recently switched from zytiga to the geberic abiraterone. I am experiencing excessive gas.
69, on lupron, xgeva,
abiraterone
and predisone. Psa less than 1.
69, on lupron, xgeva,
abiraterone
and predisone. Psa less than 1.
Mormon1
in
Advanced Prostate Cancer
3 years ago
PROTAC: An Effective Targeted Protein Degradation Strategy for Cancer Therapy
Among them, 12 patients received ARV-110 combined with enzalutamide (ENZ)/
abiraterone
(ABI), and 14 patients received prior chemotherapy.
Among them, 12 patients received ARV-110 combined with enzalutamide (ENZ)/
abiraterone
(ABI), and 14 patients received prior chemotherapy.
Scout4answers
in
Advanced Prostate Cancer
2 years ago
Which is better regarding Cognitive and Fatigue Side Effects: Abiratirone + Pred. or Enzalutamide in mCRPC?
dgcid=raven_sd_recommender_email Impact of
abiraterone
acetate plus prednisone or enzalutamide on fatigue and cognition in patients with metastatic castration-resistant prostate cancer: initial results from the observational AQUARiUS study ABSTRACT Introduction
Abiraterone
acetate plus prednisone (AAP
dgcid=raven_sd_recommender_email Impact of
abiraterone
acetate plus prednisone or enzalutamide on fatigue and cognition in patients with metastatic castration-resistant prostate cancer: initial results from the observational AQUARiUS study ABSTRACT Introduction
Abiraterone
acetate plus prednisone (AAP
MateoBeach
in
Advanced Prostate Cancer
3 years ago
PSA Rising After RP, Radiation, ADT & Clinical Trial
Albert Chang) and UCSF Androgen Annihilation clinical trial (Apalutamide +
Abiraterone
+ Prednisone in addition to ADT, his PSA was non-detectable for 1 year. Now it is on the rise again - doubling every 2 months. It's now at .25. Dr.
Albert Chang) and UCSF Androgen Annihilation clinical trial (Apalutamide +
Abiraterone
+ Prednisone in addition to ADT, his PSA was non-detectable for 1 year. Now it is on the rise again - doubling every 2 months. It's now at .25. Dr.
Jlgjdf
in
Advanced Prostate Cancer
3 years ago
Long delay getting new therapy
I failed at
Abiraterone
, and then Xofigo which was just put on hold after 3 infusions ( PSA more than doubled twice with tumor spreading as per MRIs). I continue on Lupron and am mCRPC. Thanks for any input/shared experience.
I failed at
Abiraterone
, and then Xofigo which was just put on hold after 3 infusions ( PSA more than doubled twice with tumor spreading as per MRIs). I continue on Lupron and am mCRPC. Thanks for any input/shared experience.
baltha
in
Advanced Prostate Cancer
3 years ago
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