Trying to interpret blood results? Can any of you wonderful people help.

[-missymoo]

Hello to anyone reading.

I’ve requested my most recent blood test results which gave me a Limited Systemic Sclerosis diagnosis. One thing that strikes me is the Anti dsDNA Antibodies result, my Rheumatologist has NEVER mentioned this? I’ll post a photo, if anyone is good at interpreting them, that would be great. My Antinuclear antibody ANA titre >1:100 = significant. Antinuclear antibodies POSITIVE.

Thank in advance for any response, I really appreciate any help.

[LucyJean]

Hi there, I hope I explain this ok for you. Basically what happens is you have one blood test the ANAs...the antinuclear antibody test. This is then subjected to various investigations and will come in two readings. One is the Anti ds DNA and one is ENA, which then further broken down in that list for Ro, Jo, La, Scl 70, Centromere, Sm and RNP. Each one of these is associated with a different connective tissue disease, although there can be overlap between them. The general rule is as follows. Scl 70 is diffuse scleroderma, Centromere is limited cutaneous scleroderma, Jo is myositis, Ro and La Sub acute cutaneous lupus/Sjogrens, RNP mixed connective tissue disease and Sm is specific for Lupus. The dsDNA which is listed separately is also for lupus. This is the only one that tends to change with disease activity...i.e. the bigger the number the bigger the flare. Yours says 0.3. normal is anything under 10. You don't have a positive ds DNA. The others in the ENA list tend to just mean that you are positive and regardless of how well you are they tend to stay the same.

The ANAs score is a global representative of all of the sub parts I describe above. it is positive because you have a positive score for Anti-centromere.

I really hope that makes sense. There is another lady who responds to blood test results on here as well and I am sure she will also comment if she sees your post.

All my best

Lucy xxx

[-missymoo in reply to LucyJean]

Thank you so much Lucy, you have been very helpful and you’ve explained it perfectly. You’ve helped me understand my results perfectly, I’ve a lot to learn 😃 I just read ‘consider active Lupus’ and panicked.

Thank you again. XXX

[LucyJean in reply to -missymoo]

Hey hon, I think that comment about active lupus refers to scores >50 and relates to the information to the left of it. <10 Normal, 11-50 borderline, >50 consider active lupus. But it looks like your result is the 0.3 score below. Lxxx

[-missymoo in reply to LucyJean]

You’ve been such a help 😃 xx