Treatment Update : Hello, Here is my... - SHARE Metastatic ...

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Treatment Update

Topaz_77 profile image
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Hello,

Here is my update: My sample was found to be only 10% ER-positive, which counts as being triple-negative as are most BRCA patients (I’m BRCA-1). This means I don’t benefit from hormone therapy (that explains some things!). So my next treatment will be a combo of Tecentriq (Yay! Immunotherapy!) and Abraxane. No Keytruda as has been advertised but Tecentriq specifically.

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Topaz_77
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Bubbles001 profile image
Bubbles001

I developed TNC skin mets and went on a clinical trial with Tecentriq and Lynparza (a PARP inhibitor used for ovarian cancer with much success). Skin mets cleared up. Rest of mets are stable. Side effects are minimal. The trial is still open for enrollees. You have to be BRCA positive and it works for all types of mets, but better for TNC. Anyway, it might be another option for you before adding chemo to the mix. Regardless, my experience on Tecentriq has been very positive. Best of luck to you and keep us updated with your progress.

Topaz_77 profile image
Topaz_77 in reply to Bubbles001

That’s great to read because I have definitely noticed an increase in skin mets on Ibrance. Thank you for sharing your experience. I will definitely keep the updates coming. 🙂

What do skin Mets look like? Do they itch & hurt? Since May 2019 I’ve been on IBrance/Faslodex/Xgeva for MBC. What “cures” skin METS?

Topaz_77 profile image
Topaz_77 in reply to hopenowandtomorrow

To me they look like sores or skin tags and they leak sometimes, like a sticky, clear liquid. I haven’t noticed any sensations because the skin mets are to the breast that’s still kind of numb. I believe these treatments for cancer “cure” them or at least stop them/slow down their spread.

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