Positive immunotherapy trial results

[Bubbles001]

Hi All, just thought I’d share some good news with you. I’m 18 weeks into a clinical trial combining Lynparza/Olaparib and Tecentriq/Atizo immunotherapy and my 18 week scan shows my largest liver met (6 cm) has shrunk 20% from 6 weeks ago. The other liver met and bone mets are stable. These are ER+/Her2-. My triple neg skin met on my chest is completely gone. The trial is for those with the BRCA mutation, but I understand that Tecentriq has been approved for triple negative MBC. Side effects are minimal and less than ibrance/faslodex that did not work for me. This is the first time any of my mets have shrunk, so needless to say, I am thrilled!

[Julie2233]

Fantastic news! Thank you for sharing.

[hopenowandtomorrow]

So happy for you you! Thank you for sharing this encouraging news! ❤️🙏❤️

[Hidden]

That is wonderful news! I'm really pleased for you.

[MacroMom]

That is great news! May I ask where your trial is based, or what doctor is behind it? I have the same cancer profile and would love more info. Ibrance didn’t work for me either. My ND oncologist is very optimistic about immunotherapy options. Enjoy this relief!

[Bubbles001 in reply to MacroMom]

It’s a trial led by Yale but many NCI organizations are participating across the country. I’m at Moffitt Cancer Center in Tampa. Its a phase 2 trial and they are still looking for participants. There are two arms and you are randomly assigned. One is Lynparza only and the other is both drugs. However, if you get Lynparza only, once it stops working, you are eligible for tecentriq. The tecentriq is paid by the trial. You pick up the standard of care for BRCA which is Lynparza. I think you can find the study online at one of the sites listing them.

[Bubbles001 in reply to MacroMom]

The trial number is NCI10020 and it’s called Testing Olaparib either alone or in combination with Atezolizumab in BRCA mutant non-HER2 positive breast cancer.

[Mindysooty]

How exciting for you. Fantastic news 💕

[Hidden]

Congratulations! As with all trials, good news for one is good news for all. I am thrilled it is working so we'll.❤️

[Francesca10]

Great news♥️♥️🙏🏻🙏🏻🙏🏻For continued success

Frances

[Wintervt]

So happy for you!

[AvidBooklover]

Fabulous news! Make time to celebrate!

[Evaf]

Fantastic news! xx

[Teddielottie]

Thrilled for you too ! x

[mariootsi]

How wonderful! Amazing! So happy for you. Thank you for sharing.

I wish you continued siccess in your healing.

Love,

Marianne

[mariootsi in reply to mariootsi]

Success.

[Maludagui]

Yeah 💃🏽💃🏽💃🏽❤️🌺🎀

[Wildcat1]

Awesome news!!!👏🏻👏🏻🎉🎉

[SeattleMom]

So happy for you, Bubbles!! Thanks for sharing such a wonderful piece of news!! You are in all of our hearts and prayers--ONWARD AND UPWARD!! XXOO Linda

[Kateds]

Your news is so exciting! Thank you for sharing your experience. 👍😎

[Kimr2081]

Awesome. Thanks for letting us know and giving us encouragement.

[BeckyinMaine]

Congratulations, may the drugs continue to work. Thanks for sharing

[Becca65]

Very excited to hear something new might be working. Thanking you for being a test subject!

[RLN-overcomer]

Thank you sister/warrior for this trial information, and your part in this trial study that is working to kill evict the cancer from your body. That's right cancer your on notice, here is your pink slip, adios. God is good. You are a she-heroe (sheroe), that will make it possible for other sister/warriors to win this war against this disease. Thank you also for the information on the drug Tecentriq for Triple negative breast cancer diagnosis', which was my MBC diagnosis in 2006. God bless you, as I pray to hear many more great results/testimonies from our sister/warriors. Amen XoXoXoX

[kduck]

Great news

[PLASEM]

Great news I am happy for you

[Mariote777]

Hi, sorry to bump this old thread, it's now Jan 1, 2020. Can you please share how's Tecentriq doing for you at this time? My dear wife is TNBC and may start Tec + Abraxane, I'm trying to find out as much as I can about that combo. Much appreciated.

[Bubbles001]

I recently ended the trial due to progression after 10 months. I had few side effects, so the trial was a positive experience. The really good news is that all of my TNC disappeared. All that is left is 100% ER + 100% PR+ tumors in my liver based on a liver biopsy I had last week. Best wishes on a successful treatment!