ADT with psa increasing.

[Teacherdude72]

Not newly diagnosed but need to post this:

I am on my 3rd round of hormone treatments - lupron 24 months, Casodex 9 months and now 9 months Eligard. Psa rising, now 1.16, doubled in 6 months.

What next I don't know. Started with Gleason 9 aggressive Cancer.

[Tall_Allen]

Any metastases detected?

[teacherdude70 in reply to Tall_Allen]

None via PET or MRI.

[Tall_Allen in reply to teacherdude70]

Then you can use any of the three medicines approved for non-metastatic castration-resistant PC: Nubeqa, Erleada or Xtandi

[teacherdude70 in reply to Tall_Allen]

Thanks! Had not considered those. Will reasearch then ask my Onco about them.

[Magnus1964]

It may betime to move on to abiratorone.

[teacherdude70 in reply to Magnus1964]

Would seem to be adding med or changing med. Mt T score rose significantly so maybe the psa relates to that?

[Longterm101 in reply to teacherdude70]

Any Mets at dx? When was your last shot ?

[teacherdude70 in reply to Longterm101]

Usually I have monthly shots but this time a 6 month shot. My testosterone was <5 but now 29. I feel the 6 month shot, December 28, 2020, is not as effective. No mets detected with PET Scan or MRI over the summer of 2020. Also no symptoms/bone pains.

[Longterm101 in reply to teacherdude70]

I had the same thing happen to me with a 6 month shot. I went back to every 30 days and T and PSA went back to undetectable

[teacherdude70 in reply to Longterm101]

Thanks for the insight/experience.

That is what I was thinking might be the case. However not due for next shot until June. So will ask for 100mg of Casodex until then and see what happens monthly.